The human apurinic/apyrimidinic endonuclease-1 suppresses activation of poly(adp-ribose) polymerase-1 induced by DNA single strand breaks

Toxicology

Volumn 224, Issue 1-2, 2006, Pages 44-55

  Peddi, Srinivasa R ^a   Chattopadhyay, Ranajoy ^b   Naidu, C V ^c   Izumi, Tadahide ^a  

^a LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

^c SRI VENKATESWARA UNIVERSITY   (India)

Author keywords

AP endonuclease; DNA base excision repair; Necrosis; Oxidative stress; PARP1

Indexed keywords

ARGININE; DNA (APURINIC OR APYRIMIDINIC SITE) LYASE; DNA (APURINIC OR APYRIMIDINIC SITE) LYASE 1; HYDROGEN PEROXIDE; MUTANT PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; SINGLE STRANDED DNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL DEATH; CONTROLLED STUDY; DNA CLEAVAGE; DNA DAMAGE; DNA REPAIR; DNA STRAND BREAKAGE; ENERGY CONSUMPTION; ENZYME ACTIVATION; ENZYME INHIBITION; FEMALE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MAMMAL; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DNA BINDING; WILD TYPE;

ANIMALS; BINDING, COMPETITIVE; CELL LINE; DNA DAMAGE; DNA REPAIR; DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENZYME ACTIVATION; HELA CELLS; HUMANS; MICE; POLY(ADP-RIBOSE) POLYMERASES; PROTEINS; TRANSFECTION;

MAMMALIA;

EID: 33745198464     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2006.04.025     Document Type: Article

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