SOCS1-negative feedback of STAT1 activation is a key pathway in the dsRNA-induced innate immune response of human keratinocytes

Journal of Investigative Dermatology

Volumn 126, Issue 7, 2006, Pages 1574-1581

  Dai, Xiuju ^a   Sayama, Koji ^a   Yamasaki, Kenshi ^a   Tohyama, Mikiko ^a   Shirakata, Yuji ^a   Hanakawa, Yasushi ^a   Tokumaru, Sho ^a   Yahata, Yoko ^a   Yang, Lujun ^a   Yoshimura, Akihiko ^b   Hashimoto, Koji ^a  

^a EHIME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; DOUBLE STRANDED RNA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON REGULATORY FACTOR 3; INTERFERON REGULATORY FACTOR 7; ISOPROTEIN; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; POLYINOSINIC POLYCYTIDYLIC ACID; PROTEIN STAT1F; PROTEIN STAT3F; STAT1 PROTEIN; STAT3 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 1; TOLL LIKE RECEPTOR 3; UNCLASSIFIED DRUG;

ARTICLE; CELL NUCLEUS; CELLULAR IMMUNITY; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOGENETICS; IMMUNOREGULATION; IMMUNOSTIMULATION; INNATE IMMUNITY; KERATINOCYTE; NEGATIVE FEEDBACK; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; RNA TRANSPORT; SIGNAL TRANSDUCTION; VIRUS INFECTION;

ADENOVIRUSES, HUMAN; CELLS, CULTURED; FEEDBACK, BIOCHEMICAL; GENE EXPRESSION REGULATION; GENETIC VECTORS; HOMEOSTASIS; HUMANS; IMMUNITY, NATURAL; INTERFERON REGULATORY FACTOR-3; INTERFERON REGULATORY FACTOR-7; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; KERATINOCYTES; MACROPHAGE INFLAMMATORY PROTEIN-1; NF-KAPPA B; PHOSPHORYLATION; POLY I-C; REPRESSOR PROTEINS; RNA, DOUBLE-STRANDED; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR; STAT3 TRANSCRIPTION FACTOR; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; TOLL-LIKE RECEPTOR 3;

EID: 33745191415     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/sj.jid.5700294     Document Type: Article

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