Novel sulfhydryl-reactive compounds orazipone and OR-1958 inhibit cytokine production and histamine release in rat and human mast cells

International Immunopharmacology

Volumn 5, Issue 1, 2005, Pages 177-184

  Vendelin, Johanna ^a   Laitinen, Charlotta ^a   Vainio, Petri J ^a   Nissinen, Erkki ^b   Mäki, Tiina ^c   Eklund, Kari K ^c  

^a Institute of Biomedicine   (Finland)

^b ORION CORPORATION   (Finland)

^c HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

Author keywords

Budesonide; Mast cell; Sulfhydryl reactive compound

Indexed keywords

ANTIINFLAMMATORY AGENT; BUDESONIDE; CALCIUM IONOPHORE; MESSENGER RNA; OR 1958; ORAZIPONE; PHORBOL ESTER; THIOL DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL ACTIVATION; CELL FUNCTION; CELL LINE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HISTAMINE RELEASE; HUMAN; HUMAN CELL; IC 50; MALE; MAST CELL; NONHUMAN; PERITONEUM MAST CELL; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELL LINE; FEMALE; GENE EXPRESSION REGULATION; HISTAMINE RELEASE; HUMANS; MALE; MAST CELLS; RATS; RATS, WISTAR; RNA, MESSENGER; SULFHYDRYL COMPOUNDS; SULFHYDRYL REAGENTS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 10344247644     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.intimp.2004.07.020     Document Type: Article

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