-
3
-
-
0037015882
-
Of mice and models: Improved animal models for biomedical research
-
E Bockamp M Maringer C Spangenberg S Fees S Fraser L Eshkind F Oesch B Zabel 2002 Of mice and models: improved animal models for biomedical research Physiol Genomics 11 115 132
-
(2002)
Physiol Genomics
, vol.11
, pp. 115-132
-
-
Bockamp, E.1
Maringer, M.2
Spangenberg, C.3
Fees, S.4
Fraser, S.5
Eshkind, L.6
Oesch, F.7
Zabel, B.8
-
4
-
-
0035859929
-
Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems
-
NJ Caplen S Parrish F Imani A Fire RA Morgan 2001 Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems Proc Natl Acad Sci USA 98 9742 9747
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 9742-9747
-
-
Caplen, N.J.1
Parrish, S.2
Imani, F.3
Fire, A.4
Morgan, R.A.5
-
7
-
-
10944254152
-
Transcription and processing of human microRNA precursors
-
BR Cullen 2004 Transcription and processing of human microRNA precursors Mol Cell 16 861 865
-
(2004)
Mol Cell
, vol.16
, pp. 861-865
-
-
Cullen, B.R.1
-
9
-
-
28044455435
-
MicroPrimer: The biogenesis and function of microRNA
-
T Du PD Zamore 2005 microPrimer: the biogenesis and function of microRNA Dev 132 4645 4652
-
(2005)
Dev
, vol.132
, pp. 4645-4652
-
-
Du, T.1
Zamore, P.D.2
-
11
-
-
22744433240
-
Normal microRNA maturation and germ-line stem cell maintenance requires Loquacious, a double-stranded RNA-binding domain protein
-
K Forstemann Y Tomari T Du VV Vagin AM Denli DP Bratu C Klattenhoff WE Theurkauf PD Zamore 2005 Normal microRNA maturation and germ-line stem cell maintenance requires Loquacious, a double-stranded RNA-binding domain protein PLoS Biology 3 e236
-
(2005)
PLoS Biology
, vol.3
, pp. 236
-
-
Forstemann, K.1
Tomari, Y.2
Du, T.3
Vagin, V.V.4
Denli, A.M.5
Bratu, D.P.6
Klattenhoff, C.7
Theurkauf, W.E.8
Zamore, P.D.9
-
12
-
-
0034084338
-
Induction of apoptosis by the dsRNA-dependent protein kinase (PKR): Mechanism of action
-
J Gil M Esteban 2000 Induction of apoptosis by the dsRNA-dependent protein kinase (PKR): mechanism of action Apoptosis 5 107 114
-
(2000)
Apoptosis
, vol.5
, pp. 107-114
-
-
Gil, J.1
Esteban, M.2
-
13
-
-
0037021437
-
Small interfering RNA and gene silencing in transgenic mice and rats
-
H Hasuwa K Kaseda T Einarsdottir M Okabe 2002 Small interfering RNA and gene silencing in transgenic mice and rats FEBS Lett 532 227 230
-
(2002)
FEBS Lett
, vol.532
, pp. 227-230
-
-
Hasuwa, H.1
Kaseda, K.2
Einarsdottir, T.3
Okabe, M.4
-
15
-
-
18344369543
-
MicroRNA biogenesis: Coordinated cropping and dicing
-
VN Kim 2005 MicroRNA biogenesis: coordinated cropping and dicing Nat Rev Mol Cell Biol 6 376 385
-
(2005)
Nat Rev Mol Cell Biol
, vol.6
, pp. 376-385
-
-
Kim, V.N.1
-
16
-
-
0038708339
-
Transgenic RNA interference in ES cell-derived embryos recapitulates a genetic null phenotype
-
T Kunath G Gish H Lickert N Jones T Pawson J Rossant 2003 Transgenic RNA interference in ES cell-derived embryos recapitulates a genetic null phenotype Nat Biotechnol 21 559 561
-
(2003)
Nat Biotechnol
, vol.21
, pp. 559-561
-
-
Kunath, T.1
Gish, G.2
Lickert, H.3
Jones, N.4
Pawson, T.5
Rossant, J.6
-
17
-
-
0141843656
-
The nuclear RNase III Drosha initiates microRNA processing
-
Y Lee C Ahn J Han H Choi J Kim J Yim J Lee P Provost O Radmark S Kim VN Kim 2003 The nuclear RNase III Drosha initiates microRNA processing Nature 425 415 419
-
(2003)
Nature
, vol.425
, pp. 415-419
-
-
Lee, Y.1
Ahn, C.2
Han, J.3
Choi, H.4
Kim, J.5
Yim, J.6
Lee, J.7
Provost, P.8
Radmark, O.9
Kim, S.10
Kim, V.N.11
-
18
-
-
19944406428
-
Lowering of Pkd1 expression is sufficient to cause polycystic kidney disease
-
ISL-v Leeuwen JG Dauwerse HJ Baelde WN Leonhard A van de Wal CJ Ward S Verbeek MC DeRuiter MH Breuning E de Heer DJM Peters 2004 Lowering of Pkd1 expression is sufficient to cause polycystic kidney disease Hum Mol Genet 13 3069 3077
-
(2004)
Hum Mol Genet
, vol.13
, pp. 3069-3077
-
-
Isl-V, L.1
Dauwerse, J.G.2
Baelde, H.J.3
Leonhard, W.N.4
Van De Wal, A.5
Ward, C.J.6
Verbeek, S.7
Deruiter, M.C.8
Breuning, M.H.9
De Heer, E.10
Peters, D.J.M.11
-
19
-
-
21244490466
-
Dissecting Wnt/{beta}-catenin signaling during gastrulation using RNA interference in mouse embryos
-
H Lickert B Cox C Wehrle MM Taketo R Kemler J Rossant 2005 Dissecting Wnt/{beta}-catenin signaling during gastrulation using RNA interference in mouse embryos Dev 132 2599 2609
-
(2005)
Dev
, vol.132
, pp. 2599-2609
-
-
Lickert, H.1
Cox, B.2
Wehrle, C.3
Taketo, M.M.4
Kemler, R.5
Rossant, J.6
-
21
-
-
18144393469
-
Efficiency of RNA interference in the mouse Hematopoietic system varies between cell types and developmental stages
-
P Oberdoerffer C Kanellopoulou V Heissmeyer C Paeper C Borowski I Aifantis A Rao K Rajewsky 2005 Efficiency of RNA interference in the mouse Hematopoietic system varies between cell types and developmental stages Mol Cell Biol 25 3896 3905
-
(2005)
Mol Cell Biol
, vol.25
, pp. 3896-3905
-
-
Oberdoerffer, P.1
Kanellopoulou, C.2
Heissmeyer, V.3
Paeper, C.4
Borowski, C.5
Aifantis, I.6
Rao, A.7
Rajewsky, K.8
-
22
-
-
30944469656
-
Tissue-specific RNAi reveals that WT1 expression in nurse cells controls germ cell survival and spermatogenesis
-
MK Rao J Pham JS Imam JA [tmp] MacLean D Murali Y Furuta AP Sinha-Hikim MF Wilkinson 2006 Tissue-specific RNAi reveals that WT1 expression in nurse cells controls germ cell survival and spermatogenesis Genes Dev 20 147 152
-
(2006)
Genes Dev
, vol.20
, pp. 147-152
-
-
Rao, M.K.1
Pham, J.2
Imam, J.S.3
MacLean, J.A.4
Murali, D.5
Furuta, Y.6
Sinha-Hikim, A.P.7
Wilkinson, M.F.8
-
23
-
-
0036237154
-
Dilated cardiomyopathy: Concepts derived from gene deficient and transgenic animal models
-
J Ross Jr 2002 Dilated cardiomyopathy: concepts derived from gene deficient and transgenic animal models Circ J 66 219 224
-
(2002)
Circ J
, vol.66
, pp. 219-224
-
-
Ross Jr., J.1
-
24
-
-
0037370498
-
A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference
-
DA Rubinson CP Dillon AV Kwiatkowski C Sievers L Yang J Kopinja M Zhang MT [tmp] McManus FB Gertler ML Scott L Van Parijs 2003 A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference Nat Genet 33 401 406
-
(2003)
Nat Genet
, vol.33
, pp. 401-406
-
-
Rubinson, D.A.1
Dillon, C.P.2
Kwiatkowski, A.V.3
Sievers, C.4
Yang, L.5
Kopinja, J.6
Zhang, M.7
McManus, M.T.8
Gertler, F.B.9
Scott, M.L.10
Van Parijs, L.11
-
25
-
-
26644467465
-
Single copy shRNA configuration for ubiquitous gene knockdown in mice
-
J Seibler B Kuter-Luks H Kern S Streu L Plum J Mauer R Kuhn JC Bruning F Schwenk 2005 Single copy shRNA configuration for ubiquitous gene knockdown in mice Nucl Acids Res 33 e67
-
(2005)
Nucl Acids Res
, vol.33
, pp. 67
-
-
Seibler, J.1
Kuter-Luks, B.2
Kern, H.3
Streu, S.4
Plum, L.5
Mauer, J.6
Kuhn, R.7
Bruning, J.C.8
Schwenk, F.9
-
26
-
-
0028884714
-
Genetic knockouts in mice: An update
-
BS Shastry 1995 Genetic knockouts in mice: an update Experientia 51 1028 1039
-
(1995)
Experientia
, vol.51
, pp. 1028-1039
-
-
Shastry, B.S.1
-
27
-
-
0037213559
-
Mammalian RNAi for the masses
-
Y Shi 2003 Mammalian RNAi for the masses Trends Genet 19 9 12
-
(2003)
Trends Genet
, vol.19
, pp. 9-12
-
-
Shi, Y.1
-
28
-
-
0037452812
-
A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA
-
G Tiscornia O Singer M Ikawa IM Verma 2003 A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA Proc Natl Acad Sci USA 100 1844 1848
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 1844-1848
-
-
Tiscornia, G.1
Singer, O.2
Ikawa, M.3
Verma, I.M.4
-
29
-
-
14644393684
-
Perspective: Machines for RNAi
-
Y Tomari PD Zamore 2005 Perspective: machines for RNAi Genes Dev 19 517 529
-
(2005)
Genes Dev
, vol.19
, pp. 517-529
-
-
Tomari, Y.1
Zamore, P.D.2
-
30
-
-
9144221618
-
Genomic instability and cancer: Scanning the Caenorhabditis elegans genome for tumor suppressors
-
G van Haaften RH Plasterk M Tijsterman 2004 Genomic instability and cancer: scanning the Caenorhabditis elegans genome for tumor suppressors Oncogene 23 8366 8375
-
(2004)
Oncogene
, vol.23
, pp. 8366-8375
-
-
Van Haaften, G.1
Plasterk, R.H.2
Tijsterman, M.3
-
31
-
-
3142708570
-
Cre-lox-regulated conditional RNA interference from transgenes
-
A Ventura A Meissner CP Dillon M [tmp] McManus PA Sharp L Van Parijs R Jaenisch T Jacks 2004 Cre-lox-regulated conditional RNA interference from transgenes Proc Natl Acad Sci USA 101 10380 10385
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 10380-10385
-
-
Ventura, A.1
Meissner, A.2
Dillon, C.P.3
McManus, M.4
Sharp, P.A.5
Van Parijs, L.6
Jaenisch, R.7
Jacks, T.8
-
32
-
-
0033789992
-
Specific interference with gene function by double-stranded RNA in early mouse development
-
F Wianny M Zernicka-Goetz 2000 Specific interference with gene function by double-stranded RNA in early mouse development Nat Cell Biol 2 70 75
-
(2000)
Nat Cell Biol
, vol.2
, pp. 70-75
-
-
Wianny, F.1
Zernicka-Goetz, M.2
-
33
-
-
33744819224
-
Promises and challenges in developing RNAi as a research tool and therapy for neurodegenerative diseases
-
XG Xia H Zhou ZS Xu 2005 Promises and challenges in developing RNAi as a research tool and therapy for neurodegenerative diseases Neurodeg Dis 2 220 231
-
(2005)
Neurodeg Dis
, vol.2
, pp. 220-231
-
-
Xia, X.G.1
Zhou, H.2
Xu, Z.S.3
-
34
-
-
33645788618
-
Pol II-expressed shRNA knocks down Sod2 gene expression and causes phenotypes of the gene knockout in mice
-
XG Xia H Zhou E Samper S Melov Z Xu 2006 Pol II-expressed shRNA knocks down Sod2 gene expression and causes phenotypes of the gene knockout in mice PLoS Genet 2 e10
-
(2006)
PLoS Genet
, vol.2
, pp. 10
-
-
Xia, X.G.1
Zhou, H.2
Samper, E.3
Melov, S.4
Xu, Z.5
-
35
-
-
0035667397
-
The Ons and Offs of inducible transgenic technology: A review
-
A Yamamoto R Hen WT Dauer 2001 The Ons and Offs of inducible transgenic technology: a review Neurobiol Dis 8 923 932
-
(2001)
Neurobiol Dis
, vol.8
, pp. 923-932
-
-
Yamamoto, A.1
Hen, R.2
Dauer, W.T.3
-
36
-
-
28644450043
-
An RNA polymerase II construct synthesizes short-hairpin RNA with a quantitative indicator and mediates highly efficient RNAi
-
H Zhou XG Xia Z Xu 2005 An RNA polymerase II construct synthesizes short-hairpin RNA with a quantitative indicator and mediates highly efficient RNAi Nucl Acids Res 33 e62
-
(2005)
Nucl Acids Res
, vol.33
, pp. 62
-
-
Zhou, H.1
Xia, X.G.2
Xu, Z.3
-
37
-
-
0242666144
-
Generation of fertile cloned rats by regulating oocyte activation
-
Q Zhou J-P Renard G Le Friec V Brochard N Beaujean Y Cherifi A Fraichard J Cozzi 2003 Generation of fertile cloned rats by regulating oocyte activation Science 302 1179
-
(2003)
Science
, vol.302
, pp. 1179
-
-
Zhou, Q.1
Renard, J.-P.2
Le Friec, G.3
Brochard, V.4
Beaujean, N.5
Cherifi, Y.6
Fraichard, A.7
Cozzi, J.8
|