Enantiomers of neuroactive steroids support a specific interaction with the GABA-C receptor as the mechanism of steroid action

Molecular Pharmacology

Volumn 69, Issue 6, 2006, Pages 1779-1782

  Li, Wenjun ^a   Covey, Douglas F ^a   Alakoskela, Juha Matti ^b   Kinnunen, Paavo K J ^b   Steinbach, Joe Henry ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF HELSINKI   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID C RECEPTOR; ELTANOLONE; STEROID;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG RECEPTOR BINDING; ENANTIOMER; ENANTIOSELECTIVITY; LIPID BILAYER; MEMBRANE CHANNEL; NONHUMAN; NUCLEOTIDE SEQUENCE; OOCYTE; PRIORITY JOURNAL; XENOPUS LAEVIS;

ANIMALS; ANTIPSYCHOTIC AGENTS; OOCYTES; PREGNANOLONE; RECEPTORS, GABA; STEREOISOMERISM; STEROIDS; STRUCTURE-ACTIVITY RELATIONSHIP; XENOPUS LAEVIS;

EID: 33745140915     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.106.022863     Document Type: Article

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