Catalysis by the second class of tRNA(m1G37) methyl transferase requires a conserved proline

Biochemistry

Volumn 45, Issue 24, 2006, Pages 7463-7473

  Christian, Thomas ^a   Evilia, Caryn ^a   Hou, Ya Ming ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; ENZYME KINETICS; GENES; MUTAGENESIS; RNA; SUBSTITUTION REACTIONS;

ARCHAEA; EUKARYA; METHYL TRANSFERASE; PROLINE;

ENZYMES;

AMINO ACID; GUANINE; METHYL GROUP; MUTANT PROTEIN; PROLINE; PROTEIN; S ADENOSYLMETHIONINE; TRANSFER RNA METHYLTRANSFERASE; TRM5 PROTEIN; TRMD PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANTICODON; ARCHAEBACTERIUM; ARTICLE; BACTERIAL GENE; CATALYSIS; DNA MODIFICATION; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME KINETICS; ENZYME MECHANISM; ENZYME STABILITY; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; EUKARYOTE; GENE; GENETIC CONSERVATION; METHANOCALDOCOCCUS JANNASCHII; METHYLATION; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN MOTIF; SEQUENCE ANALYSIS; STEADY STATE; TRM5 GENE; TRMD GENE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANTICODON; ARCHAEAL PROTEINS; CATALYSIS; CONSERVED SEQUENCE; DNA MUTATIONAL ANALYSIS; ENDORIBONUCLEASES; ESCHERICHIA COLI; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROLINE; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; S-ADENOSYLMETHIONINE; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY; TRNA METHYLTRANSFERASES;

ARCHAEA; EUKARYOTA; METHANOCALDOCOCCUS JANNASCHII;

EID: 33745140839     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0602314     Document Type: Article

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