Phylogenomic analysis of 16S rRNA:(guanine-N2) methyltransferases suggests new family members and reveals highly conserved motifs and a domain structure similar to other nucleic acid amino-methyltransferases

FASEB Journal

Volumn 14, Issue 14, 2000, Pages 2365-2368

  Bujnicki, Janusz M ^a,b  

^a INTERNATIONAL INSTITUTE OF MOLECULAR AND CELL BIOLOGY   (Poland)

^b HENRY FORD HEALTH SYSTEM   (United States)

Author keywords

Molecular evolution; RNA modification; Sequence alignment; Structure prediction

Indexed keywords

AMINO ACID; GUANINE DERIVATIVE; METHYLTRANSFERASE; NUCLEIC ACID; RIBOSOME RNA;

AMINO ACID SEQUENCE; ARTICLE; ENZYME ACTIVE SITE; ESCHERICHIA COLI; HUMAN; NONHUMAN; OPEN READING FRAME; PHYLOGENY; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FAMILY; RNA ANALYSIS; SEQUENCE ANALYSIS;

ESCHERICHIA COLI; GAMMAPROTEOBACTERIA;

EID: 0033729437     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.00-0076com     Document Type: Article

References (28)

1. S-adenosylmethionine-dependent methyltransferases: Structures and functions
2. Structure-based sequence alignment of three AdoMet-dependent DNA methyltransferases
3. Structure and evolution of AdoMet-dependent MTases
4. Comparison of protein structures reveals monophyletic origin of the AdoMet-dependent methyltransferase family and mechanistic convergence rather than recent differentiation of N4-cytosine and N6-adenine DNA methylation
5. Sequence of the D-aspartyl/L-isoaspartyl protein methyltransferase from human erythrocytes. Common sequence motifs for protein, DNA, RNA, and small molecule S-adenosylmethionine-dependent methyltransferases
6. Predictive motifs derived from cytosine methyltransferases
7. Structure-guided analysis reveals nine sequence motifs conserved among DNA amino-methyltransferases, and suggests a catalytic mechanism for these enzymes
8. RNA-modifying and RNA-editing enzymes: Methods for their identification
9. Identification of new RNA modifying enzymes by iterative genome search using known modifying enzymes as probes
10. Exposition of a family of RNA m(5)C methyltransferases from searching genomic and proteomic sequences
11. Multisite-specific tRNA: m5C-methyltransferase (Trm4) in yeast Saccharomyces cerevisiae: Identification of the gene and substrate specificity of the enzyme
12. Molecular evolution of DNA-(cytosine-N4) methyltransferases: Evidence for their polyphyletic origin
13. Molecular phylogenetics of DNA 5mC-methyltransferases
14. 2G1207 methyltransferase from Escherichia coli
15. Gapped BLAST and PSI-BLAST: A new generation of protein database search programs
16. The CLUSTAL X windows interface: Flexible strategies for multiple sequence alignment aided by quality analysis tools
17. Three-dimensional structure of the adenine-specific DNA methyltransferase M.TaqI in complex with the cofactor S-adenosylmethionine
18. Structural characterization of two tandemly arranged DNA methyltransferase genes from Neisseria gonorrhoeae MS11: N4-cytosine specific M.NgoMXV and nonfunctional 5-cytosine-type M.NgoMorf2P
19. Solution structure of an rRNA methyltransferase (ErmAM) that confers macrolide-lincosamide-streptogramin antibiotic resistance
20. The complete genome sequence of Escherichia coli K-12
21. The neighbor-joining method: A new method for reconstructing phylogenetic trees
22. The rapid generation of mutation data matrices from protein sequences
23. Whole-genome random sequencing and assembly of Haemophilus influenzae Rd
24. Is the HemK family of putative S-adenosylmethionine-dependent methyltransferases a 'missing'zeta subfamily of adenine methyltransferases? A hypothesis
25. Sensitive sequence comparison as protein function predictor
26. A model for DNA binding and enzyme action derived from crystallographic studies of the TaqI N6-adenine-methyltransferase
27. M.TaqI: Possible catalysis via cation-pi interactions in N-specific DNA methyltransferases