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Volumn 6, Issue 4, 2005, Pages 249-251

Acquired resistance to imatinib in gastrointestinal stromal tumours caused by multiple KIT mutations

Author keywords

[No Author keywords available]

Indexed keywords

DNA; IMATINIB; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; PLATELET DERIVED GROWTH FACTOR RECEPTOR; STEM CELL FACTOR; SUNITINIB; UNCLASSIFIED DRUG;

EID: 20144387198     PISSN: 14702045     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1470-2045(05)70097-8     Document Type: Article
Times cited : (167)

References (9)
  • 1
    • 15644363454 scopus 로고    scopus 로고
    • Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors
    • Hirota S, Isozaki K, Moriyama Y, et al. Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors. Science 1998; 279: 577-80.
    • (1998) Science , vol.279 , pp. 577-580
    • Hirota, S.1    Isozaki, K.2    Moriyama, Y.3
  • 2
    • 0242670019 scopus 로고    scopus 로고
    • PDGFRA activating mutations in gastrointestinal stromal tumors
    • Heinrich MC, Corless CL, Duensing A, et al. PDGFRA activating mutations in gastrointestinal stromal tumors. Science 2003; 299: 708-10.
    • (2003) Science , vol.299 , pp. 708-710
    • Heinrich, M.C.1    Corless, C.L.2    Duensing, A.3
  • 3
    • 0035960428 scopus 로고    scopus 로고
    • Safety and efficacy of imatinib (STI571) in metastatic gastrointestinal stromal tumors: A phase I study
    • van Osteroom AT, Judson I, Verweij J, et al. Safety and efficacy of imatinib (STI571) in metastatic gastrointestinal stromal tumors: A phase I study. Lancet 2001; 358: 1421-23
    • (2001) Lancet , vol.358 , pp. 1421-1423
    • van Osteroom, A.T.1    Judson, I.2    Verweij, J.3
  • 4
    • 0642368571 scopus 로고    scopus 로고
    • Kinase mutations and imatinib response in patients with metastatic gastrointestinal stromal tumors
    • Heinrich MC, Corless CL, Demetri GD, et al. Kinase mutations and imatinib response in patients with metastatic gastrointestinal stromal tumors. J Clin Oncol 2003; 21: 4342-49
    • (2003) J. Clin. Oncol. , vol.21 , pp. 4342-4349
    • Heinrich, M.C.1    Corless, C.L.2    Demetri, G.D.3
  • 5
    • 3042747267 scopus 로고    scopus 로고
    • Late resistance to imatinib therapy in a metastatic gastrointestinal stromal tumour is associated with a second KIT mutation
    • Wakai T, Kanda T, Hirota S, et al. Late resistance to imatinib therapy in a metastatic gastrointestinal stromal tumour is associated with a second KIT mutation. Br J Cancer 2004; 90: 2059-61
    • (2004) Br. J. Cancer , vol.90 , pp. 2059-2061
    • Wakai, T.1    Kanda, T.2    Hirota, S.3
  • 6
    • 20844448396 scopus 로고    scopus 로고
    • A new mutation in the KIT ATP pocket causes acquired resistance to imatinib in a gastrointestinal stromal tumour patient
    • Tamborini E, Bonadiman I, Greco A, et al. A new mutation in the KIT ATP pocket causes acquired resistance to imatinib in a gastrointestinal stromal tumour patient. Gastroenterology 2004; 127: 294-99.
    • (2004) Gastroenterology , vol.127 , pp. 294-299
    • Tamborini, E.1    Bonadiman, I.2    Greco, A.3
  • 7
    • 4644222221 scopus 로고    scopus 로고
    • SU11248, a multi-targeted tyrosine kinase inhibitor, can overcome imatinib (IM) resistance caused by diverse genomic mechanisms in patients (pts) with metastatic gastrointestinal stromal tumor (GIST)
    • (abstr 3001)
    • Demetri GD, Desai J, Fletcher J, et al. SU11248, a multi-targeted tyrosine kinase inhibitor, can overcome imatinib (IM) resistance caused by diverse genomic mechanisms in patients (pts) with metastatic gastrointestinal stromal tumor (GIST). J Clin Oncol 2004; 22: S14 (abstr 3001).
    • (2004) J. Clin. Oncol. , vol.22
    • Demetri, G.D.1    Desai, J.2    Fletcher, J.3
  • 8
    • 4344611744 scopus 로고    scopus 로고
    • Association of platelet-derived growth factor receptor alpha mutations with gastric primary site and epithelioid or mixed cell morphology in gastrointestinal stromal tumors
    • Wardelmann E, Hrychyk A, Merkelbach-Bruse S, et al. Association of platelet-derived growth factor receptor alpha mutations with gastric primary site and epithelioid or mixed cell morphology in gastrointestinal stromal tumors. J Mol Diagn 2004; 6: 197-204
    • (2004) J. Mol. Diagn. , vol.6 , pp. 197-204
    • Wardelmann, E.1    Hrychyk, A.2    Merkelbach-Bruse, S.3
  • 9
    • 0036141147 scopus 로고    scopus 로고
    • The complexity of KIT gene mutations and chromosome rearrangements and their clinical correlation in gastrointestinal stromal (pacemaker cell) tumors
    • Andersson LJ, Sögren H, Meis-Kindblom JM, et al. The complexity of KIT gene mutations and chromosome rearrangements and their clinical correlation in gastrointestinal stromal (pacemaker cell) tumors. Am J Pathol 2002; 160: 15-22
    • (2002) Am. J. Pathol. , vol.160 , pp. 15-22
    • Andersson, L.J.1    Sögren, H.2    Meis-Kindblom, J.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.