Cannabinoids attenuate norepinephrine-induced melatonin biosynthesis in the rat pineal gland by reducing arylalkylamine N-acetyltransferase activity without involvement of cannabinoid receptors

Journal of Neurochemistry

Volumn 98, Issue 1, 2006, Pages 267-278

  Koch, Marco ^a   Dehghani, Faramarz ^a   Habazettl, Iris ^a   Schomerus, Christof ^a   Korf, Horst Werner ^a,b  

^a GOETHE UNIVERSITY MEDICAL SCHOOL   (Germany)

^b GOETHE UNIVERSITY   (Germany)

Author keywords

Arylalkylamine N acetyltransferase; Cannabidiol; Cannabinoid system; Cannabinol; Delta 9 tetrahydrocannabinol; Melatonin biosynthesis

Indexed keywords

2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; ACETYLSEROTONIN METHYLTRANSFERASE; ARALKYLAMINE ACETYLTRANSFERASE; CALCIUM ION; CANNABIDIOL; CANNABINOID; CANNABINOID 1 RECEPTOR; CANNABINOID 2 RECEPTOR; CANNABINOID RECEPTOR AGONIST; CANNABINOID RECEPTOR ANTAGONIST; CANNABINOL; CYCLIC AMP; MELATONIN; NORADRENALIN; TETRAHYDROCANNABINOLIC ACID;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BIOSYNTHESIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; IMMOBILIZED CELL; IMMUNOCYTOCHEMISTRY; MALE; NONHUMAN; PINEAL BODY; PINEALOCYTE; PRIORITY JOURNAL; RAT; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

ANIMALS; AREA UNDER CURVE; ARYLALKYLAMINE N-ACETYLTRANSFERASE; CANNABINOIDS; CELLS, CULTURED; CYCLIC AMP; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; ENZYME ACTIVATION; ENZYME INHIBITORS; IMMUNOHISTOCHEMISTRY; MALE; MELATONIN; NOREPINEPHRINE; ORGAN CULTURE TECHNIQUES; PINEAL GLAND; RADIOMETRY; RATS; RATS, WISTAR; RECEPTORS, CANNABINOID;

EID: 33745086856     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2006.03873.x     Document Type: Article

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