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Volumn 84, Issue 4, 2006, Pages 383-389

5,6-Dimethylxanthenone-4-acetic acid treatment of a non-immunogenic tumour does not synergize with active or passive CD8+ T-cell immunotherapy

Author keywords

5,6 dimethylxanthenone 4 acetic acid (DMXAA); CD8+ T cell; Dendritic cell (DC); Immunotherapy; TNF

Indexed keywords

5,6 DIMETHYLXANTHENONE 4 ACETIC ACID;

EID: 33745067784     PISSN: 08189641     EISSN: 14401711     Source Type: Journal    
DOI: 10.1111/j.1440-1711.2006.01448.x     Document Type: Article
Times cited : (12)

References (41)
  • 1
    • 0028793675 scopus 로고
    • Bone marrow-derived dendritic cells pulsed with synthetic tumour peptides elicit protective and therapeutic antitumour immunity
    • Mayordomo JI Zorina T Storkus WJ et al. Bone marrow-derived dendritic cells pulsed with synthetic tumour peptides elicit protective and therapeutic antitumour immunity. Nat. Med. 1995 1 : 1297 302.
    • (1995) Nat. Med. , vol.1 , pp. 1297-302
    • Mayordomo, J.I.1    Zorina, T.2    Storkus, W.J.3
  • 2
    • 0030790039 scopus 로고    scopus 로고
    • Tumor-peptide-pulsed dendritic cells isolated from spleen or cultured in vitro from bone marrow precursors can provide protection against tumor challenge
    • Hermans IF Daish A Moroni-Rawson P Ronchese F. Tumor-peptide-pulsed dendritic cells isolated from spleen or cultured in vitro from bone marrow precursors can provide protection against tumor challenge. Cancer Immunol. Immunother. 1997 44 : 341 7.
    • (1997) Cancer Immunol. Immunother. , vol.44 , pp. 341-7
    • Hermans, I.F.1    Daish, A.2    Moroni-Rawson, P.3    Ronchese, F.4
  • 3
    • 0031858141 scopus 로고    scopus 로고
    • Enhancement of the anti-tumour effects of the antivascular agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA) by combination with 5-hydroxytryptamine and bioreductive drugs
    • Lash CJ Li AE Rutland M Baguley BC Zwi LJ Wilson WR. Enhancement of the anti-tumour effects of the antivascular agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA) by combination with 5-hydroxytryptamine and bioreductive drugs. Br. J. Cancer. 1998 78 : 439 45.
    • (1998) Br. J. Cancer. , vol.78 , pp. 439-45
    • Lash, C.J.1    Li, A.E.2    Rutland, M.3    Baguley, B.C.4    Zwi, L.J.5    Wilson, W.R.6
  • 4
    • 0028124643 scopus 로고
    • Correlation between immune and vascular activities of xanthenone acetic acid antitumor agents
    • Zwi LJ Baguley BC Gavin JB Wilson WR. Correlation between immune and vascular activities of xanthenone acetic acid antitumor agents. Oncol. Res. 1994 6 : 79 85.
    • (1994) Oncol. Res. , vol.6 , pp. 79-85
    • Zwi, L.J.1    Baguley, B.C.2    Gavin, J.B.3    Wilson, W.R.4
  • 5
    • 0037341637 scopus 로고    scopus 로고
    • Antivascular therapy of cancer: DMXAA
    • Baguley BC. Antivascular therapy of cancer: DMXAA. Lancet Oncol. 2003 4 : 141 8.
    • (2003) Lancet Oncol. , vol.4 , pp. 141-8
    • Baguley, B.C.1
  • 6
    • 0037125028 scopus 로고    scopus 로고
    • Induction of endothelial cell apoptosis by the antivascular agent 5,6-dimethylxanthenone-4-acetic acid
    • Ching LM Cao Z Kieda C Zwain S Jameson MB Baguley BC. Induction of endothelial cell apoptosis by the antivascular agent 5,6-dimethylxanthenone-4- acetic acid. Br. J. Cancer 2002 86 : 1937 42.
    • (2002) Br. J. Cancer , vol.86 , pp. 1937-42
    • Ching, L.M.1    Cao, Z.2    Kieda, C.3    Zwain, S.4    Jameson, M.B.5    Baguley, B.C.6
  • 7
    • 0034662648 scopus 로고    scopus 로고
    • Scintigraphic imaging of the hypoxia marker (99m)technetium-labeled 2, 2′-(1,4-diaminobutane)bis(2-methyl-3-butanone) dioxime (99mTc-labeled HL-91; Prognox): Noninvasive detection of tumor response to the antivascular agent 5,6-dimethylxanthenone-4-acetic acid
    • Siim BG Laux WT Rutland MD Palmer BN Wilson WR. Scintigraphic imaging of the hypoxia marker (99m)technetium-labeled 2, 2′-(1,4-diaminobutane)bis(2- methyl-3-butanone) dioxime (99mTc-labeled HL-91; prognox): noninvasive detection of tumor response to the antivascular agent 5,6-dimethylxanthenone-4-acetic acid. Cancer Res. 2000 60 : 4582 8.
    • (2000) Cancer Res. , vol.60 , pp. 4582-8
    • Siim, B.G.1    Laux, W.T.2    Rutland, M.D.3    Palmer, B.N.4    Wilson, W.R.5
  • 8
    • 0033565644 scopus 로고    scopus 로고
    • Induction of intratumoral tumor necrosis factor (TNF) synthesis and hemorrhagic necrosis by 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in TNF knockout mice
    • Ching LM Goldsmith D Joseph WR Korner H Sedgwick JD Baguley BC. Induction of intratumoral tumor necrosis factor (TNF) synthesis and hemorrhagic necrosis by 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in TNF knockout mice. Cancer Res. 1999 59 : 3304 307.
    • (1999) Cancer Res. , vol.59 , pp. 3304-307
    • Ching, L.M.1    Goldsmith, D.2    Joseph, W.R.3    Korner, H.4    Sedgwick, J.D.5    Baguley, B.C.6
  • 9
    • 0033083206 scopus 로고    scopus 로고
    • Stimulation of tumors to synthesize tumor necrosis factor-alpha in situ using 5,6-dimethylxanthenone-4-acetic acid: A novel approach to cancer therapy
    • Joseph WR Cao Z Mountjoy KG Marshall ES Baguley BC Ching LM. Stimulation of tumors to synthesize tumor necrosis factor-alpha in situ using 5,6-dimethylxanthenone-4-acetic acid: a novel approach to cancer therapy. Cancer Res. 1999 59 : 633 8.
    • (1999) Cancer Res. , vol.59 , pp. 633-8
    • Joseph, W.R.1    Cao, Z.2    Mountjoy, K.G.3    Marshall, E.S.4    Baguley, B.C.5    Ching, L.M.6
  • 10
    • 0037068317 scopus 로고    scopus 로고
    • The antitumour activity of 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in TNF receptor-1 knockout mice
    • Zhao L Ching LM Kestell P Baguley BC. The antitumour activity of 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in TNF receptor-1 knockout mice. Br. J. Cancer 2002 87 : 465 70.
    • (2002) Br. J. Cancer , vol.87 , pp. 465-70
    • Zhao, L.1    Ching, L.M.2    Kestell, P.3    Baguley, B.C.4
  • 11
    • 0028063124 scopus 로고
    • Activation of LPS-inducible genes by the antitumor agent 5,6-dimethylxanthenone-4-acetic acid in primary murine macrophages. Dissection of signaling pathways leading to gene induction and tyrosine phosphorylation
    • Perera PY Barber SA Ching LM Vogel SN. Activation of LPS-inducible genes by the antitumor agent 5,6-dimethylxanthenone-4-acetic acid in primary murine macrophages. Dissection of signaling pathways leading to gene induction and tyrosine phosphorylation. J. Immunol. 1994 153 : 4684 93.
    • (1994) J. Immunol. , vol.153 , pp. 4684-93
    • Perera, P.Y.1    Barber, S.A.2    Ching, L.M.3    Vogel, S.N.4
  • 12
    • 0032126120 scopus 로고    scopus 로고
    • Antitumour activity of the novel immune modulator 5,6-dimethylxanthenone- 4-acetic acid (DMXAA) in mice lacking the interferon-gamma receptor
    • Pang JH Cao Z Joseph WR Baguley BC Ching LM. Antitumour activity of the novel immune modulator 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in mice lacking the interferon-gamma receptor. Eur. J. Cancer 1998 34 : 1282 9.
    • (1998) Eur. J. Cancer , vol.34 , pp. 1282-9
    • Pang, J.H.1    Cao, Z.2    Joseph, W.R.3    Baguley, B.C.4    Ching, L.M.5
  • 13
    • 0029896957 scopus 로고    scopus 로고
    • Decrease in cellularity and expression of adhesion molecules by anti-tumor necrosis factor alpha monoclonal antibody treatment in patients with rheumatoid arthritis
    • Tak PP Taylor PC Breedveld FC et al. Decrease in cellularity and expression of adhesion molecules by anti-tumor necrosis factor alpha monoclonal antibody treatment in patients with rheumatoid arthritis. Arthritis Rheum. 1996 39 : 1077 81.
    • (1996) Arthritis Rheum. , vol.39 , pp. 1077-81
    • Tak, P.P.1    Taylor, P.C.2    Breedveld, F.C.3
  • 14
    • 0026073847 scopus 로고
    • Tumor necrosis factor combines with IL-4 or IFN-gamma to selectively enhance endothelial cell adhesiveness for T cells. the contribution of vascular cell adhesion molecule-1-dependent and -independent binding mechanisms
    • Thornhill MH Wellicome SM Mahiouz DL Lanchbury JS Kyan-Aung U Haskard DO. Tumor necrosis factor combines with IL-4 or IFN-gamma to selectively enhance endothelial cell adhesiveness for T cells. The contribution of vascular cell adhesion molecule-1-dependent and -independent binding mechanisms. J. Immunol. 1991 146 : 592 8.
    • (1991) J. Immunol. , vol.146 , pp. 592-8
    • Thornhill, M.H.1    Wellicome, S.M.2    Mahiouz, D.L.3    Lanchbury, J.S.4    Kyan-Aung, U.5    Haskard, D.O.6
  • 15
    • 0034284228 scopus 로고    scopus 로고
    • TNF-alpha associated with extracellular matrix fibronectin provides a stop signal for chemotactically migrating T cells
    • Franitza S Hershkoviz R Kam N et al. TNF-alpha associated with extracellular matrix fibronectin provides a stop signal for chemotactically migrating T cells. J. Immunol. 2000 165 : 2738 47.
    • (2000) J. Immunol. , vol.165 , pp. 2738-47
    • Franitza, S.1    Hershkoviz, R.2    Kam, N.3
  • 16
    • 0036170945 scopus 로고    scopus 로고
    • CCL27-CCR10 interactions regulate T cell-mediated skin inflammation
    • Homey B Alenius H Muller A et al. CCL27-CCR10 interactions regulate T cell-mediated skin inflammation. Nat. Med. 2002 8 : 157 65.
    • (2002) Nat. Med. , vol.8 , pp. 157-65
    • Homey, B.1    Alenius, H.2    Muller, A.3
  • 17
    • 0027512562 scopus 로고
    • Tumor necrosis factor alpha (TNF-alpha)-induced cell adhesion to human endothelial cells is under dominant control of one TNF receptor type, TNF-R55
    • Mackay F Loetscher H Stueber D Gehr G Lesslauer W. Tumor necrosis factor alpha (TNF-alpha)-induced cell adhesion to human endothelial cells is under dominant control of one TNF receptor type, TNF-R55. J. Exp. Med. 1993 177 : 1277 86.
    • (1993) J. Exp. Med. , vol.177 , pp. 1277-86
    • MacKay, F.1    Loetscher, H.2    Stueber, D.3    Gehr, G.4    Lesslauer, W.5
  • 18
    • 0024818401 scopus 로고
    • Direct expression cloning of vascular cell adhesion molecule 1, a cytokine-induced endothelial protein that binds to lymphocytes
    • Osborn L Hession C Tizard R et al. Direct expression cloning of vascular cell adhesion molecule 1, a cytokine-induced endothelial protein that binds to lymphocytes. Cell 1989 59 : 1203 11.
    • (1989) Cell , vol.59 , pp. 1203-11
    • Osborn, L.1    Hession, C.2    Tizard, R.3
  • 19
    • 0025179082 scopus 로고
    • Vascular cell adhesion molecule-1 mediates lymphocyte adherence to cytokine-activated cultured human endothelial cells
    • Carlos TM Schwartz BR Kovach NL et al. Vascular cell adhesion molecule-1 mediates lymphocyte adherence to cytokine-activated cultured human endothelial cells. Blood 1990 76 : 965 70.
    • (1990) Blood , vol.76 , pp. 965-70
    • Carlos, T.M.1    Schwartz, B.R.2    Kovach, N.L.3
  • 20
    • 0026011266 scopus 로고
    • Anti-tumour activity of flavone acetic acid (NSC 347512) in mice-influence of immune status
    • Bibby MC Phillips RM Double JA Pratesi G. Anti-tumour activity of flavone acetic acid (NSC 347512) in mice-influence of immune status. Br. J. Cancer 1991 63 : 57 62.
    • (1991) Br. J. Cancer , vol.63 , pp. 57-62
    • Bibby, M.C.1    Phillips, R.M.2    Double, J.A.3    Pratesi, G.4
  • 21
    • 0026686247 scopus 로고
    • Antitumour responses to flavone-8-acetic acid and 5,6-dimethylxanthenone- 4-acetic acid in immune deficient mice
    • Ching LM Joseph WR Baguley BC. Antitumour responses to flavone-8-acetic acid and 5,6-dimethylxanthenone-4-acetic acid in immune deficient mice. Br. J. Cancer 1992 66 : 128 30.
    • (1992) Br. J. Cancer , vol.66 , pp. 128-30
    • Ching, L.M.1    Joseph, W.R.2    Baguley, B.C.3
  • 22
    • 0025602742 scopus 로고
    • Role of T cells and tumour necrosis factor in antitumour activity and toxicity of flavone acetic acid
    • Pratesi G Rodolfo M Rovetta G Parmiani G. Role of T cells and tumour necrosis factor in antitumour activity and toxicity of flavone acetic acid. Eur. J. Cancer 1990 26 : 1079 83.
    • (1990) Eur. J. Cancer , vol.26 , pp. 1079-83
    • Pratesi, G.1    Rodolfo, M.2    Rovetta, G.3    Parmiani, G.4
  • 23
    • 29244466134 scopus 로고    scopus 로고
    • Activation of tumor-associated macrophages by the vascular disrupting agent 5,6-dimethylxanthenone-4-acetic acid induces an effective CD8+ T-cell-mediated antitumor immune response in murine models of lung cancer and mesothelioma
    • Jassar AS Suzuki E Kapoor V et al. Activation of tumor-associated macrophages by the vascular disrupting agent 5,6-dimethylxanthenone-4-acetic acid induces an effective CD8+ T-cell-mediated antitumor immune response in murine models of lung cancer and mesothelioma. Cancer Res. 2005 65 : 11 752 61.
    • (2005) Cancer Res. , vol.65 , pp. 11752-61
    • Jassar, A.S.1    Suzuki, E.2    Kapoor, V.3
  • 24
    • 0032169984 scopus 로고    scopus 로고
    • Antigen expressed on tumor cells fails to elicit an immune response, even in the presence of increased numbers of tumor-specific cytotoxic T lymphocyte precursors
    • Hermans IF Daish A Yang J Ritchie DS Ronchese F. Antigen expressed on tumor cells fails to elicit an immune response, even in the presence of increased numbers of tumor-specific cytotoxic T lymphocyte precursors. Cancer Res. 1998 58 : 3909 17.
    • (1998) Cancer Res. , vol.58 , pp. 3909-17
    • Hermans, I.F.1    Daish, A.2    Yang, J.3    Ritchie, D.S.4    Ronchese, F.5
  • 25
    • 0024307348 scopus 로고
    • Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen
    • Pircher H Burki K Lang R Hengartner H Zinkernagel RM. Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen. Nature 1989 342 : 559 61.
    • (1989) Nature , vol.342 , pp. 559-61
    • Pircher, H.1    Burki, K.2    Lang, R.3    Hengartner, H.4    Zinkernagel, R.M.5
  • 26
    • 0029858032 scopus 로고    scopus 로고
    • Functional comparison of spleen dendritic cells and dendritic cells cultured in vitro from bone marrow precursors
    • Garrigan K Moroni-Rawson P McMurray C et al. Functional comparison of spleen dendritic cells and dendritic cells cultured in vitro from bone marrow precursors. Blood 1996 88 : 3508 12.
    • (1996) Blood , vol.88 , pp. 3508-12
    • Garrigan, K.1    Moroni-Rawson, P.2    McMurray, C.3
  • 27
    • 0035575704 scopus 로고    scopus 로고
    • Tumor-specific Tc1, but not Tc2, cells deliver protective antitumor immunity
    • Kemp RA Ronchese F. Tumor-specific Tc1, but not Tc2, cells deliver protective antitumor immunity. J. Immunol. 2001 167 : 6497 502.
    • (2001) J. Immunol. , vol.167 , pp. 6497-502
    • Kemp, R.A.1    Ronchese, F.2
  • 30
    • 0034121654 scopus 로고    scopus 로고
    • Dendritic cells in cancer immunotherapy
    • Fong L Engleman EG. Dendritic cells in cancer immunotherapy. Annu. Rev. Immunol. 2000 18 : 245 73.
    • (2000) Annu. Rev. Immunol. , vol.18 , pp. 245-73
    • Fong, L.1    Engleman, E.G.2
  • 31
    • 0029063213 scopus 로고
    • Induction of tumour necrosis factor-alpha by single and repeated doses of the antitumour agent 5,6-dimethylxanthenone-4-acetic acid
    • Philpott M Baguley BC Ching LM. Induction of tumour necrosis factor-alpha by single and repeated doses of the antitumour agent 5,6-dimethylxanthenone-4- acetic acid. Cancer Chemother. Pharmacol. 1995 36 : 143 8.
    • (1995) Cancer Chemother. Pharmacol. , vol.36 , pp. 143-8
    • Philpott, M.1    Baguley, B.C.2    Ching, L.M.3
  • 32
    • 0026507383 scopus 로고
    • Dermal tumour necrosis factor-alpha induces dendritic cell migration to draining lymph nodes, and possibly provides one stimulus for Langerhans' cell migration
    • Cumberbatch M Kimber I. Dermal tumour necrosis factor-alpha induces dendritic cell migration to draining lymph nodes, and possibly provides one stimulus for Langerhans' cell migration. Immunology 1992 75 : 257 63.
    • (1992) Immunology , vol.75 , pp. 257-63
    • Cumberbatch, M.1    Kimber, I.2
  • 33
    • 0030725852 scopus 로고    scopus 로고
    • Langerhans cells require signals from both tumour necrosis factor-alpha and interleukin-1 beta for migration
    • Cumberbatch M Dearman RJ Kimber I. Langerhans cells require signals from both tumour necrosis factor-alpha and interleukin-1 beta for migration. Immunology 1997 92 : 388 95.
    • (1997) Immunology , vol.92 , pp. 388-95
    • Cumberbatch, M.1    Dearman, R.J.2    Kimber, I.3
  • 34
    • 2542574206 scopus 로고    scopus 로고
    • CD8+ T cell cross-priming via transfer of proteasome substrates
    • Norbury CC Basta S Donohue KB et al. CD8+ T cell cross-priming via transfer of proteasome substrates. Science 2004 304 : 1318 21.
    • (2004) Science , vol.304 , pp. 1318-21
    • Norbury, C.C.1    Basta, S.2    Donohue, K.B.3
  • 37
    • 20544433550 scopus 로고    scopus 로고
    • Peptides chaperoned by heat-shock proteins are a necessary and sufficient source of antigen in the cross-priming of CD8+ T cells
    • and
    • Binder RJ and Srivastava PK. Peptides chaperoned by heat-shock proteins are a necessary and sufficient source of antigen in the cross-priming of CD8+ T cells. Nat. Immunol. 2005 6 : 593 9.
    • (2005) Nat. Immunol. , vol.6 , pp. 593-9
    • Binder, R.J.1    Srivastava, P.K.2
  • 38
    • 0033980648 scopus 로고    scopus 로고
    • Processing of some antigens by the standard proteasome but not by the immunoproteasome results in poor presentation by dendritic cells
    • Morel S Levy F Burlet-Schiltz O et al. Processing of some antigens by the standard proteasome but not by the immunoproteasome results in poor presentation by dendritic cells. Immunity 2000 12 : 107 17.
    • (2000) Immunity , vol.12 , pp. 107-17
    • Morel, S.1    Levy, F.2    Burlet-Schiltz, O.3
  • 39
    • 0023934095 scopus 로고
    • Flavone-8-acetic acid augments systemic natural killer cell activity and synergizes with IL-2 for treatment of murine renal cancer
    • Wiltrout RH Boyd MR Back TC Salup RR Arthur JA Hornung RL. Flavone-8-acetic acid augments systemic natural killer cell activity and synergizes with IL-2 for treatment of murine renal cancer. J. Immunol. 1988 140 : 3261 5.
    • (1988) J. Immunol. , vol.140 , pp. 3261-5
    • Wiltrout, R.H.1    Boyd, M.R.2    Back, T.C.3    Salup, R.R.4    Arthur, J.A.5    Hornung, R.L.6
  • 40
    • 0023685071 scopus 로고
    • Augmentation of natural killer activity, induction of IFN and development tumor immunity during the successful treatment of established murine renal cancer using flavone acetic acid and IL-2
    • Hornung RL Back TC Zaharko DS Urba WJ Longo DL Wiltrout RH. Augmentation of natural killer activity, induction of IFN and development tumor immunity during the successful treatment of established murine renal cancer using flavone acetic acid and IL-2. J. Immunol. 1988 141 : 3671 9.
    • (1988) J. Immunol. , vol.141 , pp. 3671-9
    • Hornung, R.L.1    Back, T.C.2    Zaharko, D.S.3    Urba, W.J.4    Longo, D.L.5    Wiltrout, R.H.6
  • 41
    • 0035266136 scopus 로고    scopus 로고
    • Vascular attack by 5,6-dimethylxanthenone-4-acetic acid combined with B7.1 (CD80)-mediated immunotherapy overcomes immune resistance and leads to the eradication of large tumors and multiple tumor foci
    • Kanwar JR Kanwar RK Pandey S Ching LM Krissansen GW. Vascular attack by 5,6-dimethylxanthenone-4-acetic acid combined with B7.1 (CD80)-mediated immunotherapy overcomes immune resistance and leads to the eradication of large tumors and multiple tumor foci. Cancer Res. 2001 61 : 1948 56.
    • (2001) Cancer Res. , vol.61 , pp. 1948-56
    • Kanwar, J.R.1    Kanwar, R.K.2    Pandey, S.3    Ching, L.M.4    Krissansen, G.W.5


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