-
1
-
-
0034077041
-
Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system
-
Abeliovich A. Schmitz Y. Farinas I. Choi-Lundberg D. Ho W.H. Castillo P.E. Shinsky N. Verdugo J.M. Armanini M. Ryan A. Hynes M. Phillips H. Sulzer D. Rosenthal A. ( 2000) Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system. Neuron, 25, 239 252.
-
(2000)
Neuron
, vol.25
, pp. 239-252
-
-
Abeliovich, A.1
Schmitz, Y.2
Farinas, I.3
Choi-Lundberg, D.4
Ho, W.H.5
Castillo, P.E.6
Shinsky, N.7
Verdugo, J.M.8
Armanini, M.9
Ryan, A.10
Hynes, M.11
Phillips, H.12
Sulzer, D.13
Rosenthal, A.14
-
2
-
-
0036468432
-
Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease
-
Auluck P.K. Chan H.Y. Trojanowski J.Q. Lee V.M. Bonini N.M. ( 2002) Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease. Science, 295, 865 868.
-
(2002)
Science
, vol.295
, pp. 865-868
-
-
Auluck, P.K.1
Chan, H.Y.2
Trojanowski, J.Q.3
Lee, V.M.4
Bonini, N.M.5
-
3
-
-
1542285887
-
New Drosophila transgenic reporters: Insulated P-element vectors expressing fast-maturing RFP
-
Barolo S. Castro B. Posakony J.W. ( 2004) New Drosophila transgenic reporters: insulated P-element vectors expressing fast-maturing RFP. Biotechniques, 36, 436 442.
-
(2004)
Biotechniques
, vol.36
, pp. 436-442
-
-
Barolo, S.1
Castro, B.2
Posakony, J.W.3
-
4
-
-
29444455075
-
Drosophila as a model for human neurodegenerative disease
-
Bilen J. Bonini N.M. ( 2005) Drosophila as a model for human neurodegenerative disease. Ann. Rev. Genet, 39, 153 171.
-
(2005)
Ann. Rev. Genet
, vol.39
, pp. 153-171
-
-
Bilen, J.1
Bonini, N.M.2
-
5
-
-
0028034952
-
A novel and major isoform of tyrosine hydroxylase in Drosophila is generated by alternative RNA processing
-
Birman S. Morgan B. Anzivino M. Hirsh J. ( 1994) A novel and major isoform of tyrosine hydroxylase in Drosophila is generated by alternative RNA processing. J. Biol. Chem., 269, 26559 26567.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 26559-26567
-
-
Birman, S.1
Morgan, B.2
Anzivino, M.3
Hirsh, J.4
-
6
-
-
0027160708
-
Targeted gene expression as a means of altering cell fates and generating dominant phenotypes
-
Brand A.H. Perrimon N. ( 1993) Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development, 118, 401 415.
-
(1993)
Development
, vol.118
, pp. 401-415
-
-
Brand, A.H.1
Perrimon, N.2
-
8
-
-
6944227811
-
Double-knockout mice for alpha- and beta-synucleins: Effect on synaptic functions
-
Chandra S. Fornai F. Kwon H.B. Yazdani U. Atasoy D. Liu X. Hammer R.E. Battaglia G. German D.C. Castillo P.E. Sudhof T.C. ( 2004) Double-knockout mice for alpha- and beta-synucleins: effect on synaptic functions. Proc. Natl Acad. Sci. USA, 101, 14966 14971.
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 14966-14971
-
-
Chandra, S.1
Fornai, F.2
Kwon, H.B.3
Yazdani, U.4
Atasoy, D.5
Liu, X.6
Hammer, R.E.7
Battaglia, G.8
German, D.C.9
Castillo, P.E.10
Sudhof, T.C.11
-
9
-
-
22244442489
-
The biochemistry of Parkinson's disease
-
Cookson M.R. ( 2005) The biochemistry of Parkinson's disease. Ann. Rev. Biochem., 74, 29 52.
-
(2005)
Ann. Rev. Biochem.
, vol.74
, pp. 29-52
-
-
Cookson, M.R.1
-
10
-
-
0141741347
-
Parkinson's disease: Mechanisms and models
-
Dauer W. Przedborski S. ( 2003) Parkinson's disease: mechanisms and models. Neuron, 39, 889 909.
-
(2003)
Neuron
, vol.39
, pp. 889-909
-
-
Dauer, W.1
Przedborski, S.2
-
11
-
-
0242363670
-
Molecular pathways of neurodegeneration in Parkinson's disease
-
Dawson T.M. Dawson V.L. ( 2003) Molecular pathways of neurodegeneration in Parkinson's disease. Science, 302, 819 822.
-
(2003)
Science
, vol.302
, pp. 819-822
-
-
Dawson, T.M.1
Dawson, V.L.2
-
12
-
-
0345119026
-
Caught in the act: α-synuclein is the culprit in Parkinson's disease
-
Eriksen J.L. Dawson T.M. Dickson D.W. Petrucelli L. ( 2003) Caught in the act: α-synuclein is the culprit in Parkinson's disease. Neuron, 40, 453 456.
-
(2003)
Neuron
, vol.40
, pp. 453-456
-
-
Eriksen, J.L.1
Dawson, T.M.2
Dickson, D.W.3
Petrucelli, L.4
-
13
-
-
0034704752
-
A Drosophila model of Parkinson's disease
-
Feany M.B. Bender W.W. ( 2000) A Drosophila model of Parkinson's disease. Nature, 404, 394 398.
-
(2000)
Nature
, vol.404
, pp. 394-398
-
-
Feany, M.B.1
Bender, W.W.2
-
14
-
-
0037370716
-
Targeted gene expression in Drosophila dopaminergic cells using regulatory sequences from tyrosine hydroxylase
-
Friggi-Grelin F. Coulom H. Meller M. Gomez D. Hirsh J. Birman S. ( 2003a) Targeted gene expression in Drosophila dopaminergic cells using regulatory sequences from tyrosine hydroxylase. J. Neurobiol., 54, 618 627.
-
(2003)
J. Neurobiol.
, vol.54
, pp. 618-627
-
-
Friggi-Grelin, F.1
Coulom, H.2
Meller, M.3
Gomez, D.4
Hirsh, J.5
Birman, S.6
-
15
-
-
0037350778
-
Tissue-specific developmental requirements of Drosophila tyrosine hydroxylase isoforms
-
Friggi-Grelin F. Iche M. Birman S. ( 2003b) Tissue-specific developmental requirements of Drosophila tyrosine hydroxylase isoforms. Genesis, 35, 260 269.
-
(2003)
Genesis
, vol.35
, pp. 260-269
-
-
Friggi-Grelin, F.1
Iche, M.2
Birman, S.3
-
16
-
-
0038784529
-
Are ubiquitination pathways central to Parkinson's disease?
-
Giasson B.I. Lee V.M. ( 2003) Are ubiquitination pathways central to Parkinson's disease? Cell, 114, 1 8.
-
(2003)
Cell
, vol.114
, pp. 1-8
-
-
Giasson, B.I.1
Lee, V.M.2
-
17
-
-
0035252410
-
Alternative splicing: Increasing diversity in the proteomic world
-
Graveley B.R. ( 2001) Alternative splicing: increasing diversity in the proteomic world. Trends Genet., 17, 100 107.
-
(2001)
Trends Genet.
, vol.17
, pp. 100-107
-
-
Graveley, B.R.1
-
18
-
-
0020121682
-
Antibodies to horseradish peroxidase as specific neuronal markers in Drosophila and grasshopper embryos
-
Jan L. Jan Y. ( 1982) Antibodies to horseradish peroxidase as specific neuronal markers in Drosophila and grasshopper embryos. Proc. Natl Acad. Sci. USA, 79, 2700 2704.
-
(1982)
Proc. Natl Acad. Sci. USA
, vol.79
, pp. 2700-2704
-
-
Jan, L.1
Jan, Y.2
-
19
-
-
0034721690
-
Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease
-
Kordower J.H. Emborg M.E. Bloch J. Ma S.Y. Chu Y. Leventhal L. McBride J. Chen E.Y. Palfi S. Roitberg B.Z. Brown W.D. Holden J.E. Pyzalski R. Taylor M.D. Carvey P. Ling Z. Trono D. Hantraye P. Deglon N. Aebischer P. ( 2000) Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease. Science, 290, 767 773.
-
(2000)
Science
, vol.290
, pp. 767-773
-
-
Kordower, J.H.1
Emborg, M.E.2
Bloch, J.3
Ma, S.Y.4
Chu, Y.5
Leventhal, L.6
McBride, J.7
Chen, E.Y.8
Palfi, S.9
Roitberg, B.Z.10
Brown, W.D.11
Holden, J.E.12
Pyzalski, R.13
Taylor, M.D.14
Carvey, P.15
Ling, Z.16
Trono, D.17
Hantraye, P.18
Deglon, N.19
Aebischer, P.20
more..
-
20
-
-
1942425204
-
A new culturing strategy optimises Drosophila primary cell cultures for structural and functional analyses
-
Kuppers-Munther B. Letzkus J.J. Luer K. Technau G. Schmidt H. Prokop A ( 2004) A new culturing strategy optimises Drosophila primary cell cultures for structural and functional analyses. Dev. Biol., 269, 459 478.
-
(2004)
Dev. Biol.
, vol.269
, pp. 459-478
-
-
Kuppers-Munther, B.1
Letzkus, J.J.2
Luer, K.3
Technau, G.4
Schmidt, H.5
Prokop, A.6
-
21
-
-
0033168976
-
Fast excitatory synaptic transmission mediated by nicotinic acetylcholine receptors in Drosophila neurons
-
Lee D. O'Dowd D.K. ( 1999) Fast excitatory synaptic transmission mediated by nicotinic acetylcholine receptors in Drosophila neurons. J. Neurosci., 19, 5311 5321.
-
(1999)
J. Neurosci.
, vol.19
, pp. 5311-5321
-
-
Lee, D.1
O'Dowd, D.K.2
-
22
-
-
0027943318
-
Temporal and spatial development of serotonin and dopamine neurons in the Drosophila CNS
-
Lundell M.J. Hirsh J. ( 1994) Temporal and spatial development of serotonin and dopamine neurons in the Drosophila CNS. Dev. Biol., 165, 385 396.
-
(1994)
Dev. Biol.
, vol.165
, pp. 385-396
-
-
Lundell, M.J.1
Hirsh, J.2
-
25
-
-
0036514504
-
Modelling neurodegenerative diseases in Drosophila: A fruitful approach?
-
Muqit M.M. Feany M.B. ( 2002) Modelling neurodegenerative diseases in Drosophila: a fruitful approach? Nat. Rev. Neurosci., 3, 237 243.
-
(2002)
Nat. Rev. Neurosci.
, vol.3
, pp. 237-243
-
-
Muqit, M.M.1
Feany, M.B.2
-
26
-
-
0028915784
-
Voltage-gated currents and firing properties of embryonic Drosophila neurons grown in a chemically defined medium
-
O'Dowd D.K. ( 1995) Voltage-gated currents and firing properties of embryonic Drosophila neurons grown in a chemically defined medium. J. Neurobiol., 27, 113 126.
-
(1995)
J. Neurobiol.
, vol.27
, pp. 113-126
-
-
O'Dowd, D.K.1
-
27
-
-
30444457574
-
The alpha-synuclein mutation E46K promotes aggregation in cultured cells
-
Pandey N. Schmidt R.E. Galvin J.E. ( 2006) The alpha-synuclein mutation E46K promotes aggregation in cultured cells. Exp. Neurol., 197, 515 520.
-
(2006)
Exp. Neurol.
, vol.197
, pp. 515-520
-
-
Pandey, N.1
Schmidt, R.E.2
Galvin, J.E.3
-
28
-
-
0036137083
-
Effects of pharmacological agents upon a transgenic model of Parkinson's disease in Drosophila melanogaster
-
Pendleton R.G. Parvez F. Sayed M. Hillman R. ( 2002) Effects of pharmacological agents upon a transgenic model of Parkinson's disease in Drosophila melanogaster. J. Pharmacol. Exp. Ther., 300, 91 96.
-
(2002)
J. Pharmacol. Exp. Ther.
, vol.300
, pp. 91-96
-
-
Pendleton, R.G.1
Parvez, F.2
Sayed, M.3
Hillman, R.4
-
29
-
-
18544362489
-
Whole-mount analysis reveals normal numbers of dopaminergic neurons following misexpression of alpha-Synuclein in Drosophila
-
Pesah Y. Burgess H. Middlebrooks B. Ronningen K. Prosser J. Tirunagaru V. Zysk J. Mardon G. ( 2005) Whole-mount analysis reveals normal numbers of dopaminergic neurons following misexpression of alpha-Synuclein in Drosophila. Genesis, 41, 154 159.
-
(2005)
Genesis
, vol.41
, pp. 154-159
-
-
Pesah, Y.1
Burgess, H.2
Middlebrooks, B.3
Ronningen, K.4
Prosser, J.5
Tirunagaru, V.6
Zysk, J.7
Mardon, G.8
-
30
-
-
0001951786
-
Drosophila cholinergic neurons and processes visualized with Gal4/UAS-GFP
-
Salvaterra P.M. Kitamoto T. ( 2001) Drosophila cholinergic neurons and processes visualized with Gal4/UAS-GFP. Brain Res. Gene Expr. Patterns, 1, 73 82.
-
(2001)
Brain Res. Gene Expr. Patterns
, vol.1
, pp. 73-82
-
-
Salvaterra, P.M.1
Kitamoto, T.2
-
31
-
-
20444416315
-
Alpha-synuclein phosphorylation enhances eosinophilic cytoplasmic inclusion formation in SH-SY5Y cells
-
Smith W.W. Margolis R.L. Li X. Troncoso J.C. Lee M.K. Dawson V.L. Dawson T.M. Iwatsubo T. Ross C.A. ( 2005) Alpha-synuclein phosphorylation enhances eosinophilic cytoplasmic inclusion formation in SH-SY5Y cells. J. Neurosci., 25, 5544 5552.
-
(2005)
J. Neurosci.
, vol.25
, pp. 5544-5552
-
-
Smith, W.W.1
Margolis, R.L.2
Li, X.3
Troncoso, J.C.4
Lee, M.K.5
Dawson, V.L.6
Dawson, T.M.7
Iwatsubo, T.8
Ross, C.A.9
-
32
-
-
20344369560
-
Increased glutathione S-transferase activity rescues dopaminergic neuron loss in a Drosophila model of Parkinson's disease
-
Whitworth A.J. Theodore D.A. Greene J.C. Benes H. Wes P.D. Pallanck L.J. ( 2005) Increased glutathione S-transferase activity rescues dopaminergic neuron loss in a Drosophila model of Parkinson's disease. Proc. Natl Acad. Sci. USA, 102, 8024 8029.
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 8024-8029
-
-
Whitworth, A.J.1
Theodore, D.A.2
Greene, J.C.3
Benes, H.4
Wes, P.D.5
Pallanck, L.J.6
-
33
-
-
0036278335
-
Dopamine-dependent neurotoxicity of α-synuclein: A mechanism for selective neurodegeneration in Parkinson disease
-
Xu J. Kao S.Y. Lee F.J. Song W. Jin L.W. Yankner B.A. ( 2002) Dopamine-dependent neurotoxicity of α-synuclein: a mechanism for selective neurodegeneration in Parkinson disease. Nat. Med., 8, 600 606.
-
(2002)
Nat. Med.
, vol.8
, pp. 600-606
-
-
Xu, J.1
Kao, S.Y.2
Lee, F.J.3
Song, W.4
Jin, L.W.5
Yankner, B.A.6
-
34
-
-
0037468831
-
Parkin suppresses dopaminergic neuron-selective neurotoxicity induced by Pael-R in Drosophila
-
Yang Y. Nishimura I. Imai Y. Takahashi R. Lu B. ( 2003) Parkin suppresses dopaminergic neuron-selective neurotoxicity induced by Pael-R in Drosophila. Neuron, 37, 911 924.
-
(2003)
Neuron
, vol.37
, pp. 911-924
-
-
Yang, Y.1
Nishimura, I.2
Imai, Y.3
Takahashi, R.4
Lu, B.5
-
35
-
-
0036468957
-
Overexpression of human alpha-synuclein causes dopamine neuron death in primary human mesencephalic culture
-
Zhou W. Schaack J. Zawada W.M. Freed C.R. ( 2001) Overexpression of human alpha-synuclein causes dopamine neuron death in primary human mesencephalic culture. Brain Res., 926, 42 50.
-
(2001)
Brain Res.
, vol.926
, pp. 42-50
-
-
Zhou, W.1
Schaack, J.2
Zawada, W.M.3
Freed, C.R.4
|