Resistance to HIV Infection

Journal of Urban Health

Volumn 83, Issue 1, 2006, Pages 5-17

  Marmor, M ^a   Hertzmark, K ^a   Thomas, S M ^a   Halkitis, P N ^a,b   Vogler, M ^c  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NEW YORK UNIVERSITY   (United States)

^c WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

HIV infection; Progression; Resistance; Susceptibility

Indexed keywords

CHEMOKINE; CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR4; CYTOKINE; HLA A ANTIGEN; HLA ANTIGEN; HLA B ANTIGEN; HLA C ANTIGEN; INTERLEUKIN 4; INTERLEUKIN DERIVATIVE;

CONFERENCE PAPER; DISEASE COURSE; DISEASE PREDISPOSITION; GENETIC POLYMORPHISM; HEPATITIS G VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNE RESPONSE; INFECTION RESISTANCE; MEDICAL RESEARCH; PRIORITY JOURNAL; PROSTITUTION; ATTITUDE TO HEALTH; GENETICS; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMUNOLOGY; INNATE IMMUNITY; MUTATION; PHYSIOLOGY; REVIEW; VIROLOGY; VIRUS INFECTION;

CHEMOKINES; DISEASE SUSCEPTIBILITY; FLAVIVIRIDAE INFECTIONS; GB VIRUS C; HEALTH KNOWLEDGE, ATTITUDES, PRACTICE; HIV INFECTIONS; HIV-1; HLA ANTIGENS; HUMANS; IMMUNITY, NATURAL; INTERLEUKINS; MUTATION; POLYMORPHISM, GENETIC; PROSTITUTION; RECEPTORS, CHEMOKINE;

EID: 33745054989     PISSN: 10993460     EISSN: 14682869     Source Type: Journal    
DOI: 10.1007/s11524-005-9003-8     Document Type: Conference Paper

References (69)

1. Fowke KR, Nagelkerke NJ, Kimani J, et al. Resistance to HIV-1 infection among persistently seronegative prostitutes in Nairobi, Kenya. Lancet. 1996;348(9038):1347-1351.
2. Kaul R, Dong T, Plummer FA, et al. CD8(+) lymphocytes respond to different HIV epitopes in seronegative and infected subjects. J Clin Invest. 2001;107(10):1303-1310.
3. Kaul R, Rutherford J, Rowland-Jones SL, et al. HIV-1 Env-specific cytotoxic T-lymphocyte responses in exposed, uninfected Kenyan sex workers: a prospective analysis. AIDS. 2004;18(15):2087-2089.
4. McNicholl JM, Promadej N. Insights into the role of host genetic and T-cell factors in resistance to HIV transmission from studies of highly HIV-exposed Thais. Immunol Res. 2004;29(1-3):161-174.
5. Goh WC, Markee J, Akridge RE, et al. Protection against human immunodeficiency virus type 1 infection in persons with repeated exposure: evidence for T cell immunity in the absence of inherited CCR5 coreceptor defects. J Infect Dis. 1999;179(3):548-557.
6. Hoffman R. Hematology: Basic Principles and Practice. 4th ed. Elsevier; 2005.
7. Farquhar C, Rowland-Jones S, Mbori-Ngacha D, et al. Human leukocyte antigen (HLA) B*18 and protection against mother-to-child HIV type 1 transmission. AIDS Res Hum Retrovir. 2004;20(7):692-697.
8. Kuhn L, Coutsoudis A, Moodley D, et al. T-helper cell responses to HIV envelope peptides in cord blood: protection against intrapartum and breast-feeding transmission. AIDS. 2001;15(1):1-9.
9. Clerici M, Levin JM, Kessler HA, et al. HIV-specific T-helper activity in seronegative health care workers exposed to contaminated blood. JAMA. 1994;271(1):42-46.
10. Pinto LA, Sullivan J, Berzofsky JA, et al. ENV-specific cytotoxic T lymphocyte responses in HIV seronegative health care workers occupationally exposed to HIV-contaminated body fluids. J Clin Invest. 1995;96(2):867-876.
11. Makedonas G, Bruneau J, Lin H, Sekaly RP, Lamothe F, Bernard NF. HIV-specific CD8 T-cell activity in uninfected injection drug users is associated with maintenance of seronegativity. AIDS. 2002;16(12):1595-1602.
12. Barretina J, Blanco J, Gutierrez A, et al. Evaluation of the putative role of C-C chemokines as protective factors of HIV-1 infection in seronegative hemophiliacs exposed to contaminated hemoderivatives. Transfusion. 2000;40(4):461-467.
13. Easterbrook PJ. Long-term non-progression in HIV infection: definitions and epidemiological issues. J Infect. 1999;38(2):71-73.
14. Marmor M, Sheppard HW, Donnell D, et al. Homozygous and heterozygous CCR5-Delta32 genotypes are associated with resistance to HIV infection. J Acquir Immune Defic Syndr. 2001;27(5):472-481.
15. Salkowitz JR, Bruse SE, Meyerson H, et al. CCR5 promoter polymorphism determines macrophage CCR5 density and magnitude of HIV-1 propagation in vitro. Clin Immunol. 2003;108(3):234-240.
16. O'Brien SJ, Moore JP. The effect of genetic variation in chemokines and their receptors on HIV transmission and progression to AIDS. Immunol Rev. 2000;177:99-111.
17. de Silva E, Stumpf MP. HIV and the CCR5-Delta32 resistance allele. FEMS Microbiol Lett. 2004;241(1):1-12.
18. Pokorny V, McQueen F, Yeoman S, et al. Evidence for negative association of the chemokine receptor CCR5 d32 polymorphism with rheumatoid arthritis. Ann Rheum Dis. 2005;64(3):487-490.
19. Contopoulos-Ioannidis DG, O'Brien TR, Goedert JJ, Rosenberg PS, Ioannidis JP. Effect of CCR5-delta32 heterozygosity on the risk of perinatal HIV-1 infection: a meta-analysis.[erratum appears in J Acquir Immune Defic Syndr. 2003 Apr 15;32(5):575]. J Acquir Immune Defic Syndr. 2003;32(1):70-76.
20. Philpott S, Weiser B, Tarwater P, et al. CC chemokine receptor 5 genotype and susceptibility to transmission of human immunodeficiency virus type 1 in women. J Infect Dis. 2003;187(4):569-575.
21. Hogan CM, Hammer SM. Host determinants in HIV infection and disease. Part 2: genetic factors and implications for antiretroviral therapeutics. Ann Intern Med. 2001;134(10):978-996.
22. Kostrikis LG. Impact of natural chemokine receptor polymorphisms on perinatal transmission of human immunodeficiency virus type 1. Teratology. 2000;61(5):387-390.
23. Louisirirotchanakul S, Liu H, Roongpisuthipong A, et al. Genetic analysis of HIV-1 discordant couples in Thailand: association of CCR2 64I homozygosity with HIV-1-negative status. J Acquir Immune Defic Syndr. 2002;29(3):314-315.
24. Kaslow RA, Dorak T, Tang JJ. Influence of host genetic variation on susceptibility to HIV type 1 infection. J Infect Dis. 2005;191(Suppl 1):S68-S77.
25. Ioannidis JP, Rosenberg PS, Goedert JJ, et al. Effects of CCR5-Delta32, CCR2-64I, and SDF-1 3′A alleles on HIV-1 disease progression: an international meta-analysis of individual-patient data. Ann Intern Med. 2001;135(9):782-795.
26. Valentin A, Lu W, Rosati M, et al. Dual effect of interleukin 4 on HIV-1 expression: implications for viral phenotypic switch and disease progression. Proc Natl Acad Sci USA. 1998;95(15):8886-8891.
27. Nakayama EE, Hoshino Y, Xin X, et al. Polymorphism in the interleukin-4 promoter affects acquisition of human immunodeficiency virus type 1 syncytium-inducing phenotype. J Virol. 2000;74(12):5452-5459.
28. Nakayama EE, Meyer L, Iwamoto A, et al. Protective effect of interleukin-4 -589T polymorphism on human immunodeficiency virus type 1 disease progression: relationship with virus load. J Infect Dis. 2002;185(8):1183-1186.
29. Kwa D, van Rij RP, Boeser-Nunnink B, Vingerhoed J, Schuitemaker H. Association between an interleukin-4 promoter polymorphism and the acquisition of CXCR4 using HIV-1 variants. AIDS. 2003;17(7):981-985.
30. Singh KK, Hughes MD, Chen J, Spector SA. Lack of protective effects of interleukin-4-589-C/T polymorphism against HIV-1-related disease progression and central nervous system impairment, in children. J Infect Dis. 2004;189(4):587-592.
31. Kollmann TR, Pettoello-Mantovani M, Katopodis NF, et al. Inhibition of acute in vivo human immunodeficiency virus infection by human interleukin 10 treatment of SCID mice implanted with human fetal thymus and liver. Proc Natl Acad Sci USA. 1996;93(7):3126-3131.
32. Shin HD, Winkler C, Stephens JC, et al. Genetic restriction of HIV-1 pathogenesis to AIDS by promoter alleles of IL10. Proc Natl Acad Sci USA. 2000;97(26):14467-14472.
33. Carrington M, O'Brien SJ. The influence of HLA genotype on AIDS. Annu Rev Med. 2003;54:535-551.
34. Rowland-Jones SL, Dong T, Fowke KR, et al. Cytotoxic T cell responses to multiple conserved HIV epitopes in HIV-resistant prostitutes in Nairobi. J Clin Invest. 1998;102(9):1758-1765.
35. Rowland-Jones SL, McMichael A. Immune responses in HIV-exposed seronegatives: have they repelled the virus? Curr Opin Immunol. 1995;7(4):448-455.
36. Rowland-Jones SL, Nixon DF, Aldhous MC, et al. HIV-specific cytotoxic T-cell activity in an HIV-exposed but uninfected infant. Lancet. 1993;341(8849):860-861.
37. Dorak MT, Tang J, Penman-Aguilar A, et al. Transmission of HIV-1 and HLA-B allele-sharing within serodiscordant heterosexual Zambian couples. Lancet. 2004;363(9427):f2137-2139.
38. MacDonald KS, Embree J, Njenga S, et al. Mother-child class I HLA concordance increases perinatal human immunodeficiency virus type 1 transmission. J Infect Dis. 1998;177(3):551-556.
39. MacDonald KS, Fowke KR, Kimani J, et al. Influence of HLA supertypes on susceptibility and resistance to human immunodeficiency virus type 1 infection. J Infect Dis. 2000;181(5):1581-1589.
40. MacDonald KS, Embree JE, Nagelkerke NJ, et al. The HLA A2/6802 supertype is associated with reduced risk of perinatal human immunodeficiency virus type 1 transmission. J Infect Dis. 2001;183(3):503-506.
41. Ahuja SK, Catano G. Sharing is caring, except when it comes to HLA-class-I alleles in HIV-1 transmission. Lancet. 2004;363(9427):2103-2104.
42. Yang C, Li M, Limpakarnjanarat K, et al. Polymorphisms in the CCR5 coding and noncoding regions among HIV type 1-exposed, persistently seronegative female sex-workers from Thailand. AIDS Res Human Retrovir. 2003;19(8):661-665.
43. Kaul R, Rowland-Jones SL, Kimani J, et al. New insights into HIV-1 specific cytotoxic T-lymphocyte responses in exposed, persistently seronegative Kenyan sex workers. Immunol Lett. 2001;79(1-2):3-13.
44. Rowland-Jones SL, Pinheiro S, Kaul R, et al. How important is the 'quality' of the cytotoxic T lymphocyte (CTL) response in protection against HIV infection? Immunol Lett. 2001;79:15-20.
45. Kaul R, Plummer FA, Kimani J, et al. HIV-1-specific mucosal CD8+ lymphocyte responses in the cervix of HIV-1-resistant prostitutes in Nairobi. J Immunol. 2000;164(3):1602-1611.
46. Kaul R, Rowland-Jones SL, Kimani J, et al. Late seroconversion in HIV-resistant Nairobi prostitutes despite pre-existing HIV-specific CD8+ responses.[comment]. J Clin Invest. 2001;107(3):341-349.
47. Beyrer C, Artenstein AW, Rugpao S, et al. Epidemiologiv and biologic characterization of a cohort of human immunodeficiency virus type 1 highly exposed, persistently seronegative female sex workers in Northern Thailand. J Infect Dis. 1999;179:59-67.
48. Broliden K, Hinkula J, Devito C, et al. Functional HIV-1 specific IgA antibodies in HIV-1 exposed, persistently IgG seronegative female sex workers. Immunol Lett. 2001;79:29-36.
49. Belec L, Ghys PD, Hocini H, et al. Cervicovaginal secretory antibodies to human immunodeficiency virus type 1 (HIV-1) that block viral transcytosis through tight epithelial barriers in highly exposed HIV-1-seronegative African women. J Infect Dis. 2001;184(11):1412-1422.
50. Polgreen PM, Xiang J, Chang Q, Stapleton JT. GB virus type C/hepatitis G virus: a non-pathogenic flavivirus associated with prolonged survival in HIV-infected individuals. Microbes Infect. 2003;5(13):1255-1261.
51. Williams CF, Klinzman D, Yamashita TE, et al. Persistent GB virus C infection and survival in HIV-infected men. N Engl J Med. 2004;350(10):981-990.
52. Xiang J, Wunschmann S, Diekema DJ, et al. Effect of coinfection with GB virus C on survival among patients with HIV infection. N Engl J Med. 2001;345(10):707-714.
53. Pomerantz RJ, Nunnari G. HIV and GB virus C - can two viruses be better than one? N Engl J Med 2004;350(10):963-965.
54. Canducci F, Uberti Foppa C, Boeri E, et al. Characterization of GBV-C infection in HIV-1 infected patients. J Biol Regul Homeost Agents. 2003;17(2):191-194.
55. Royce RA, Sena A, Cates W Jr., Cohen MS. Sexual transmission of HIV. N Engl J Med. 1997;336(15):1072-1078.
56. Sha BE, Zariffard MR, Wang QJ, et al. Female genital-tract HIV load correlates inversely with Lactobacillus species but positively with bacterial vaginosis and Mycoplasma hominis. J Infect Dis. 2005;191(1):25-32.
57. Celum CL, Robinson NJ, Cohen MS. Potential effect of HIV type 1 antiretroviral and herpes simplex virus type 2 antiviral therapy on transmission and acquisition of HIV type 1 infection. J Infect Dis. 2005;191(Suppl 1):S107-S114.
58. Seed J, Allen S, Mertens T, et al. Male circumcision, sexually transmitted disease, and risk of HIV. J Acquir Immune Defic Syndr Human Retrovirol. 1995;8(1):83-90.
59. Auvert B, Taljaard D, Lagarde E, Sobngwi-Tambekou J, Sitta R, Puren A. Randomized, controlled intervention trial of male circumcision for reduction of HIV infection risk: the ANRS 1265 trial. PLoS Med. 2005;2(11):e298.
60. Lowy E, Ross MW. "It'll never happen to me": gay men's beliefs, perceptions and folk constructions of sexual risk. AIDS Educ Prev. 1994;6(6):467-482.
61. Halkitis PN, Parsons JT. Oral sex and HIV risk reduction: perceived risk, behavior and strategies among young HIV negative gay men. J Psychol Human Sex. 2000;11(4):1-24.
62. Des Jarlais DC, Vanichseni S, Marmor M, et al. "Why I am not infected with HIV": implications for long-term HIV risk reduction and HIV vaccine trials. J Acquir Immune Defic Syndr Human Retrovirol. 1997;16(5):393-399.
63. Fishbein M. The role of theory in HIV prevention. AIDS Care. 2000;12(3):273-278.
64. Cochran SD, Keidan J, Kalechstein A. Sexually transmitted diseases and acquired immunodeficiency syndrome (AIDS). Changes in risk reduction behaviors among young adults. Sex Transm Dis. 1990;17(2):80-86.
65. Bartholow BN, Buchbinder S, Celum C, et al. HIV sexual risk behavior over 36 months of follow-up in the world's first HIV vaccine efficacy trial. J Acquir Immune Defic Syndr. 2005;39(1):90-101.
66. Aspinwall LG, Kemeny ME, Taylor SE, Schneider SG, Dudley JP. Psychosocial predictors of gay men's AIDS risk-reduction behavior. Health Psychol. 1991;10(6):432-444.
67. Halkitis PN, Zade DD, Shrem M, Marmor M. Beliefs about HIV non-infection and risky sexual behavior among MSM. AIDS Educ Prev. 2004;16(5):448-458.
68. Ho DD, Neumann AU, Perelson AS, Chen W, Leonard JM, Markowitz M. Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection. Nature. 1995;373(6510):123-126.
69. Wodarz D, Nowak MA. Mathematical models of HIV pathogenesis and treatment. BioEssays. 2002;24(12):1178-1187.