N-terminal proteolysis of the endothelin B receptor abolishes its ability to induce EGF receptor transactivation and contractile protein expression in vascular smooth muscle cells

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 26, Issue 6, 2006, Pages 1288-1296

  Grantcharova, Evelina ^a,b   Reusch, H Peter ^c   Grossmann, Solveig ^a   Eichhorst, Jenny ^b   Krell, Hans Willi ^d   Beyermann, Michael ^b   Rosenthal, Walter ^a,b   Oksche, Alexander ^a,b  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b LEIBNIZ INSTITUT FÜR MOLEKULARE PHARMAKOLOGIE   (Germany)

^c RUHR UNIVERSITY BOCHUM   (Germany)

^d ROCHE DIAGNOSTICS GMBH   (Germany)

Author keywords

Differentiation; EGF receptor; ERK1 2; Transactivation

Indexed keywords

ALPHA ACTIN; CONTRACTILE PROTEIN; ENDOTHELIN B RECEPTOR; ENDOTHELIN B RECEPTOR AGONIST; EPIDERMAL GROWTH FACTOR RECEPTOR; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; METALLOPROTEINASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MYOSIN I; MYOSIN II; SUCCINYLENDOTHELIN 1 [8-21][9 GLUTAMIC ACID 11,15 ALANINE]; ENDOTHELIN; GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; PEPTIDE FRAGMENT; PEPTIDE HYDROLASE;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; IMMUNOHISTOCHEMISTRY; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; RAT; SMOOTH MUSCLE FIBER; TRANSACTIVATION; VASCULAR SMOOTH MUSCLE; ANIMAL; CELL CULTURE; CHEMISTRY; CYTOLOGY; DRUG EFFECT; DRUG POTENTIATION; GENETICS; HUMAN; METABOLISM; MUTATION; PHYSIOLOGY;

ANIMALS; CELLS, CULTURED; CONTRACTILE PROTEINS; ENDOTHELINS; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GREEN FLUORESCENT PROTEINS; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; HUMANS; MUSCLE, SMOOTH, VASCULAR; MUTATION; MYOCYTES, SMOOTH MUSCLE; PEPTIDE FRAGMENTS; PEPTIDE HYDROLASES; RATS; RECEPTOR, ENDOTHELIN B; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECOMBINANT FUSION PROTEINS; TRANS-ACTIVATION (GENETICS);

EID: 33745010737     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.0000220377.51354.30     Document Type: Article

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