-
1
-
-
33745004520
-
-
Amylin Pharmaceuticals Inc. Data on file.
-
-
-
-
2
-
-
0021682554
-
Semisynthetic human insulin and purified pork insulin do not differ in their biological potency
-
Arias P., Kerner W., Navascues I., Schafauer G., and Pfieffer E.F. Semisynthetic human insulin and purified pork insulin do not differ in their biological potency. Klin Wochenschr 24 (1984) 1145-1150
-
(1984)
Klin Wochenschr
, vol.24
, pp. 1145-1150
-
-
Arias, P.1
Kerner, W.2
Navascues, I.3
Schafauer, G.4
Pfieffer, E.F.5
-
3
-
-
0025941325
-
Leeches, snakes, ticks, and vampire bats in today's cardiovascular drug development
-
Bang N.U. Leeches, snakes, ticks, and vampire bats in today's cardiovascular drug development. Circulation 84 (1991) 436-438
-
(1991)
Circulation
, vol.84
, pp. 436-438
-
-
Bang, N.U.1
-
4
-
-
4644351840
-
Pure red cell aplasia and epoetin therapy
-
Bennett C.L., Luminari S., Nissenson A.R., Tallman M.S., Klinge S.A., Mc Williams N., et al. Pure red cell aplasia and epoetin therapy. N Engl J Med 35 (2004) 1403-1408
-
(2004)
N Engl J Med
, vol.35
, pp. 1403-1408
-
-
Bennett, C.L.1
Luminari, S.2
Nissenson, A.R.3
Tallman, M.S.4
Klinge, S.A.5
Mc Williams, N.6
-
5
-
-
13544255754
-
-
Benucci M., Li Gobbi F., Fossi F., Manfredi M., and Del Rosso A. J Clin Rheumatol 1 (2005) 47-49
-
(2005)
J Clin Rheumatol
, vol.1
, pp. 47-49
-
-
Benucci, M.1
Li Gobbi, F.2
Fossi, F.3
Manfredi, M.4
Del Rosso, A.5
-
6
-
-
0000522927
-
Insulin-I-131 metabolism in human subjects: demonstration of insulin binding globulin in the circulation of insulin treated subjects
-
Berson S.A., Yalow R.S., Bauman A., Rothschild M.A., and Newerly K. Insulin-I-131 metabolism in human subjects: demonstration of insulin binding globulin in the circulation of insulin treated subjects. J Clin Invest 35 (1956) 170
-
(1956)
J Clin Invest
, vol.35
, pp. 170
-
-
Berson, S.A.1
Yalow, R.S.2
Bauman, A.3
Rothschild, M.A.4
Newerly, K.5
-
7
-
-
2642526933
-
Neutralizing antibodies to interferon beta: implications for the management of multiple sclerosis
-
Bertolotto A. Neutralizing antibodies to interferon beta: implications for the management of multiple sclerosis. Curr Opin Neurol 17 (2004) 241-246
-
(2004)
Curr Opin Neurol
, vol.17
, pp. 241-246
-
-
Bertolotto, A.1
-
8
-
-
0033856063
-
Autoimmunity against pancreatic islets and other tissues before and after interferon-alpha therapy in patients with hepatitis C virus chronic infection
-
Betterle C., Fabris P., Zanchetta R., Pedini B., Tositti G., Bosi E., et al. Autoimmunity against pancreatic islets and other tissues before and after interferon-alpha therapy in patients with hepatitis C virus chronic infection. Diabetes Care 23 (2000) 1177-1181
-
(2000)
Diabetes Care
, vol.23
, pp. 1177-1181
-
-
Betterle, C.1
Fabris, P.2
Zanchetta, R.3
Pedini, B.4
Tositti, G.5
Bosi, E.6
-
9
-
-
33745003348
-
-
Bhavsar S, Watkins J, Young A. Comparison of central and peripheral effects of exendin-4 and GLP-1 on food intake in rats. Program and Abstracts: 80th Annual Meeting of the Endocrine Society, 1988 [abstract P3-223].
-
-
-
-
10
-
-
0014431776
-
Effects of calcitonin on patients with Paget's disease, thyrotoxicosism or hypercalcemia
-
Bijvoet O.L.M., van der Sluys J., and Jansen A.P. Effects of calcitonin on patients with Paget's disease, thyrotoxicosism or hypercalcemia. Lancet 1 (1968) 876
-
(1968)
Lancet
, vol.1
, pp. 876
-
-
Bijvoet, O.L.M.1
van der Sluys, J.2
Jansen, A.P.3
-
11
-
-
84920236401
-
Autoimmunity in diabetics induced by hormonal contaminants of insulin
-
Bloom S.R., Barnes A.J., Adrian T.E., and Polak J.M. Autoimmunity in diabetics induced by hormonal contaminants of insulin. Lancet 1 (1979) 14-17
-
(1979)
Lancet
, vol.1
, pp. 14-17
-
-
Bloom, S.R.1
Barnes, A.J.2
Adrian, T.E.3
Polak, J.M.4
-
12
-
-
0034950094
-
Fulminant autoimmune type 1 diabetes during interferon-alpha therapy: a case of Th1-mediated disease?
-
Bosi E., Minelli R., Bazzigaluppi E., and Salvi M. Fulminant autoimmune type 1 diabetes during interferon-alpha therapy: a case of Th1-mediated disease?. Diabetic Med 18 (2001) 329-332
-
(2001)
Diabetic Med
, vol.18
, pp. 329-332
-
-
Bosi, E.1
Minelli, R.2
Bazzigaluppi, E.3
Salvi, M.4
-
13
-
-
7444228521
-
Effects of exenatide (exendin-4) on glycemic control over 30 weeks in sulfonylurea-treated patients with type 2 diabetes
-
Buse J.B., Henry R.R., Han J., Kim D.D., Fineman M.S., Alain D., et al. Effects of exenatide (exendin-4) on glycemic control over 30 weeks in sulfonylurea-treated patients with type 2 diabetes. Diabetes Care 27 (2004) 2628-2635
-
(2004)
Diabetes Care
, vol.27
, pp. 2628-2635
-
-
Buse, J.B.1
Henry, R.R.2
Han, J.3
Kim, D.D.4
Fineman, M.S.5
Alain, D.6
-
14
-
-
33745003808
-
-
® (exenatide) injection, Prescribing information. www.byetta.com. Byetta is a registered trademark of Amylin Pharmaceuticals Inc.
-
-
-
-
15
-
-
0037075272
-
Pure red-cell aplasia and antierythropoietin antibodies in patients treated with recombinant erythropoietin
-
Casadevall N., Nataf J., Viron B., Kolta A., Kiladjian J.J., Martin-Dupont P., et al. Pure red-cell aplasia and antierythropoietin antibodies in patients treated with recombinant erythropoietin. N Engl J Med 34 (2002) 469-475
-
(2002)
N Engl J Med
, vol.34
, pp. 469-475
-
-
Casadevall, N.1
Nataf, J.2
Viron, B.3
Kolta, A.4
Kiladjian, J.J.5
Martin-Dupont, P.6
-
16
-
-
0041804230
-
An overview of scientific and regulatory issues for the imunogenicity of biological products
-
Chamberlain P., and Mire-Sluis A.R. An overview of scientific and regulatory issues for the imunogenicity of biological products. Dev Biol 112 (2003) 3-11
-
(2003)
Dev Biol
, vol.112
, pp. 3-11
-
-
Chamberlain, P.1
Mire-Sluis, A.R.2
-
18
-
-
0031040794
-
Tissue-specific expression of unique mRNAs that encode pro-glucagon-derived peptides or exendin-4 in the lizard
-
Chen Y.E., and Drucker D. Tissue-specific expression of unique mRNAs that encode pro-glucagon-derived peptides or exendin-4 in the lizard. J Biol Chem 272 (1997) 4108-4115
-
(1997)
J Biol Chem
, vol.272
, pp. 4108-4115
-
-
Chen, Y.E.1
Drucker, D.2
-
19
-
-
0842304936
-
Minimizing the immunogenicity of protein therapeutics
-
Chirino A.J., Ary M.L., and Marshall S.A. Minimizing the immunogenicity of protein therapeutics. Drug Disc Today 9 (2004) 282-290
-
(2004)
Drug Disc Today
, vol.9
, pp. 282-290
-
-
Chirino, A.J.1
Ary, M.L.2
Marshall, S.A.3
-
20
-
-
8344224534
-
Characterizing biological products and assessing comparability following manufacturing changes
-
Chirino A.J., and Mire-Sluis A. Characterizing biological products and assessing comparability following manufacturing changes. Nat Biotech 11 (2004) 1383-1390
-
(2004)
Nat Biotech
, vol.11
, pp. 1383-1390
-
-
Chirino, A.J.1
Mire-Sluis, A.2
-
21
-
-
0030034912
-
Elimination of the action of glucagon-like peptide 1 causes an impairment of glucose tolerance after nutrient ingestion by healthy baboons
-
D'Alessio D.A., Vogel R., Prigeon R., Laschansky E., Koerker D., Eng J., et al. Elimination of the action of glucagon-like peptide 1 causes an impairment of glucose tolerance after nutrient ingestion by healthy baboons. J Clin Invest 97 (1996) 133-138
-
(1996)
J Clin Invest
, vol.97
, pp. 133-138
-
-
D'Alessio, D.A.1
Vogel, R.2
Prigeon, R.3
Laschansky, E.4
Koerker, D.5
Eng, J.6
-
22
-
-
0021811863
-
The immunogenicity of new insulins
-
Deckert T. The immunogenicity of new insulins. Diabetes 34 Suppl. 2 (1985) 94-96
-
(1985)
Diabetes
, vol.34
, Issue.SUPPL. 2
, pp. 94-96
-
-
Deckert, T.1
-
23
-
-
18144401971
-
Effects of exenatide (exendin-4) on glycemic control and weight over 30 weeks in metformin-treated patients with type 2 diabetes
-
DeFronzo R.A., Ratner R.E., Han J., Kim D.D., Fineman M.S., and Baron A.D. Effects of exenatide (exendin-4) on glycemic control and weight over 30 weeks in metformin-treated patients with type 2 diabetes. Diabetes Care 28 (2005) 1092-1100
-
(2005)
Diabetes Care
, vol.28
, pp. 1092-1100
-
-
DeFronzo, R.A.1
Ratner, R.E.2
Han, J.3
Kim, D.D.4
Fineman, M.S.5
Baron, A.D.6
-
24
-
-
4344713643
-
Effect of intravenous infusion of exenatide (synthetic exendin-4) on glucose-dependent insulin secretion and counterregulation during hypoglycemia
-
Degn K.B., Brock B., Juhl C.B., Djurhuus C.B., Grubert J., Kim D., et al. Effect of intravenous infusion of exenatide (synthetic exendin-4) on glucose-dependent insulin secretion and counterregulation during hypoglycemia. Diabetes 53 (2004) 2397-2403
-
(2004)
Diabetes
, vol.53
, pp. 2397-2403
-
-
Degn, K.B.1
Brock, B.2
Juhl, C.B.3
Djurhuus, C.B.4
Grubert, J.5
Kim, D.6
-
25
-
-
0018622334
-
Formation of antibodies to synthetic human calcitonin during treatment of Paget's disease
-
Deitrich F.M., Fischer J.A., and Bijvoet O.L.M. Formation of antibodies to synthetic human calcitonin during treatment of Paget's disease. Acta Endocrin 92 (1979) 468-476
-
(1979)
Acta Endocrin
, vol.92
, pp. 468-476
-
-
Deitrich, F.M.1
Fischer, J.A.2
Bijvoet, O.L.M.3
-
26
-
-
0016230850
-
Response of Paget's disease to porcine and salmon calcitonins
-
DeRose J., Singer F.R., Avramides A., Flores A., Dziadiw R., Baker R.K., et al. Response of Paget's disease to porcine and salmon calcitonins. Am J Med 56 (1974) 858-866
-
(1974)
Am J Med
, vol.56
, pp. 858-866
-
-
DeRose, J.1
Singer, F.R.2
Avramides, A.3
Flores, A.4
Dziadiw, R.5
Baker, R.K.6
-
27
-
-
0037737732
-
Outpatient insulin therapy in type 1 and type 2 diabetes mellitus: a scientific review
-
DeWitt D.E., and Hirsch I.B. Outpatient insulin therapy in type 1 and type 2 diabetes mellitus: a scientific review. JAMA 289 (2003) 2254-2264
-
(2003)
JAMA
, Issue.289
, pp. 2254-2264
-
-
DeWitt, D.E.1
Hirsch, I.B.2
-
28
-
-
0034814047
-
Exendin-4 reduces fasting and postprandial glucose and decreases energy intake in healthy volunteers
-
Edward C.M., Stanley S.A., Davis R., Brynes A.E., Frost G.S., Seal L.J., et al. Exendin-4 reduces fasting and postprandial glucose and decreases energy intake in healthy volunteers. Am J Physiol Endocrinol Metab 281 (2001) E155-E161
-
(2001)
Am J Physiol Endocrinol Metab
, vol.281
-
-
Edward, C.M.1
Stanley, S.A.2
Davis, R.3
Brynes, A.E.4
Frost, G.S.5
Seal, L.J.6
-
29
-
-
0036965113
-
The insulinotropic effect of acute exendin-4 administered to humans: comparison of nondiabetic state to type 2 diabetes
-
Egan J.M., Clocquet A.R., and Elahi D. The insulinotropic effect of acute exendin-4 administered to humans: comparison of nondiabetic state to type 2 diabetes. J Clin Endocrinol Metab 87 (2002) 1282-1290
-
(2002)
J Clin Endocrinol Metab
, vol.87
, pp. 1282-1290
-
-
Egan, J.M.1
Clocquet, A.R.2
Elahi, D.3
-
30
-
-
0026648961
-
Isolation and characterization of exendin-4, an exendin-3 analogue from Heloderma suspectum venom
-
Eng J., Kleinman W.A., Singh L., et al. Isolation and characterization of exendin-4, an exendin-3 analogue from Heloderma suspectum venom. J Biol Chem 267 (1992) 7402-7405
-
(1992)
J Biol Chem
, vol.267
, pp. 7402-7405
-
-
Eng, J.1
Kleinman, W.A.2
Singh, L.3
-
31
-
-
0020529811
-
Effects of species of origin, purification levels, and formulation on insulin immunogenicity
-
Fineberg S.E., Galloway J.A., Fineberg N.S., and Goldman J. Effects of species of origin, purification levels, and formulation on insulin immunogenicity. Diabetes 32 (1983) 592-599
-
(1983)
Diabetes
, vol.32
, pp. 592-599
-
-
Fineberg, S.E.1
Galloway, J.A.2
Fineberg, N.S.3
Goldman, J.4
-
32
-
-
0021073383
-
Immunogenicity of recombinant DNA human insulin
-
Fineberg S.E., Galloway J.A., Fineberg N.S., Rathbun M.J., and Hufferd S. Immunogenicity of recombinant DNA human insulin. Diabetologia 25 (1983) 465-469
-
(1983)
Diabetologia
, vol.25
, pp. 465-469
-
-
Fineberg, S.E.1
Galloway, J.A.2
Fineberg, N.S.3
Rathbun, M.J.4
Hufferd, S.5
-
33
-
-
0042189526
-
Insulin allergy and insulin resistance
-
Lebovitz H.E. (Ed), American Diabetes Association, Alexandria, Virginia
-
Fineberg S.E. Insulin allergy and insulin resistance. In: Lebovitz H.E. (Ed). Therapy for diabetes mellitus and related disorders (1994), American Diabetes Association, Alexandria, Virginia 178-184
-
(1994)
Therapy for diabetes mellitus and related disorders
, pp. 178-184
-
-
Fineberg, S.E.1
-
34
-
-
0020418338
-
Development of IgE antibodies to human (recombinant DNA) porcine, and bovine insulins in diabetic subjects
-
Fireman P., Fineberg S.E., and Galloway J.A. Development of IgE antibodies to human (recombinant DNA) porcine, and bovine insulins in diabetic subjects. Diabetes Care 5 Suppl. 2 (1982) 119-125
-
(1982)
Diabetes Care
, vol.5
, Issue.SUPPL. 2
, pp. 119-125
-
-
Fireman, P.1
Fineberg, S.E.2
Galloway, J.A.3
-
35
-
-
0014052088
-
ACTH antibodies in patients receiving depot porcine ACTH to hasten recovery from pituitary-adrenal suppression
-
Fleischer N., Abe K., Liddle G.W., Orth D.N., and Nicholson W.E. ACTH antibodies in patients receiving depot porcine ACTH to hasten recovery from pituitary-adrenal suppression. J Clin Invest 46 (1967) 196-204
-
(1967)
J Clin Invest
, vol.46
, pp. 196-204
-
-
Fleischer, N.1
Abe, K.2
Liddle, G.W.3
Orth, D.N.4
Nicholson, W.E.5
-
36
-
-
14044254868
-
2004 approvals: the demise of the blockbuster?
-
Frantz S. 2004 approvals: the demise of the blockbuster?. Nat Rev Drug Discov 4 (2005) 93-94
-
(2005)
Nat Rev Drug Discov
, vol.4
, pp. 93-94
-
-
Frantz, S.1
-
37
-
-
0025937492
-
Effective thrombolysis without marked plasminemia after bolus intravenous administration of vampire bat salivary plasminogen activator in rabbits
-
Gardell S.J., Ramjit D.R., Stabilito I.I., Fujita T., Lynch J.J., Cuca G.C., et al. Effective thrombolysis without marked plasminemia after bolus intravenous administration of vampire bat salivary plasminogen activator in rabbits. Circulation 84 (1991) 244-253
-
(1991)
Circulation
, vol.84
, pp. 244-253
-
-
Gardell, S.J.1
Ramjit, D.R.2
Stabilito, I.I.3
Fujita, T.4
Lynch, J.J.5
Cuca, G.C.6
-
39
-
-
33744978683
-
Formation of neutralizing antibodies against human calcitonin in a patients with postmenopausal osteoporosis
-
Grauer A., Reinel H.H., Ljunghall S., Lindh E., Ziegler R., and Raue F. Formation of neutralizing antibodies against human calcitonin in a patients with postmenopausal osteoporosis. Calcif Tissue Int 52 Suppl. 1 (1993) 317
-
(1993)
Calcif Tissue Int
, vol.52
, Issue.SUPPL. 1
, pp. 317
-
-
Grauer, A.1
Reinel, H.H.2
Ljunghall, S.3
Lindh, E.4
Ziegler, R.5
Raue, F.6
-
41
-
-
19944426190
-
The desmoteplase in acute ischemic stroke trial (DIAS): a phase 2 MRI-based 9-hour window acute stroke thrombolysis trial with intravenous desmoteplase
-
Hacke W., Albers G., Al-Rawi Y., Bogousslavsky J., and Davalos A. The desmoteplase in acute ischemic stroke trial (DIAS): a phase 2 MRI-based 9-hour window acute stroke thrombolysis trial with intravenous desmoteplase. Stroke 36 (2005) 66-73
-
(2005)
Stroke
, vol.36
, pp. 66-73
-
-
Hacke, W.1
Albers, G.2
Al-Rawi, Y.3
Bogousslavsky, J.4
Davalos, A.5
-
42
-
-
0015462482
-
Calcitonin resistance: clinical and immunological studies in subjects with Paget's disease of bone treated with porcine and salmon calcitonins
-
Haddad J.G., and Caldwell J.G. Calcitonin resistance: clinical and immunological studies in subjects with Paget's disease of bone treated with porcine and salmon calcitonins. J Clin Invest 51 (1972) 3133-3141
-
(1972)
J Clin Invest
, vol.51
, pp. 3133-3141
-
-
Haddad, J.G.1
Caldwell, J.G.2
-
43
-
-
0031846102
-
The biology of interferon-alpha and the clinical significance of anti-interferon antibodies
-
Hanley J.P., and Haydon G.H. The biology of interferon-alpha and the clinical significance of anti-interferon antibodies. Leuk Lymphoma 29 (1998) 257-268
-
(1998)
Leuk Lymphoma
, vol.29
, pp. 257-268
-
-
Hanley, J.P.1
Haydon, G.H.2
-
44
-
-
33744987557
-
Validation of an ELISA used to determine anti-exenatide antibody cross-reactivity to GLP-1 and glucagon in human plasma samples
-
Heintz G., Waterhouse T., Petrella E., Fischer K., and Hiles R. Validation of an ELISA used to determine anti-exenatide antibody cross-reactivity to GLP-1 and glucagon in human plasma samples. AAPS Pharm Sci. 6 October (2004)
-
(2004)
AAPS Pharm Sci.
, vol.6
, Issue.October
-
-
Heintz, G.1
Waterhouse, T.2
Petrella, E.3
Fischer, K.4
Hiles, R.5
-
46
-
-
0020698715
-
Comparison of the activity and pharmacokinetics of porcine insulin and human insulin as assessed by the glucose clamp technique in normal and diabetic man
-
Home P.D., Shepherd G.A., Noy G., Massi-Benedetti M., Hanning I., Burrin J.M., et al. Comparison of the activity and pharmacokinetics of porcine insulin and human insulin as assessed by the glucose clamp technique in normal and diabetic man. Diabetes Care 6 (1983) 23-28
-
(1983)
Diabetes Care
, vol.6
, pp. 23-28
-
-
Home, P.D.1
Shepherd, G.A.2
Noy, G.3
Massi-Benedetti, M.4
Hanning, I.5
Burrin, J.M.6
-
47
-
-
0021126701
-
A fifteen-month double-blind cross-over study of the efficacy and antigenicity of human and pork insulin
-
Home P.D., Mann N.P., Hutchison A.S., Park R., Walford S., Murphy M., et al. A fifteen-month double-blind cross-over study of the efficacy and antigenicity of human and pork insulin. Diabet Med 1 (1984) 93-98
-
(1984)
Diabet Med
, vol.1
, pp. 93-98
-
-
Home, P.D.1
Mann, N.P.2
Hutchison, A.S.3
Park, R.4
Walford, S.5
Murphy, M.6
-
48
-
-
0020454508
-
The therapeutic efficacy of human insulin (recombinant DNA) in patients with insulin-dependent diabetes mellitus: a comparative study with purified porcine insulin
-
Howley D.C., Fineberg S.E., Nolen P.A., Stone M., Gibson R.G., Fineberg N.S., et al. The therapeutic efficacy of human insulin (recombinant DNA) in patients with insulin-dependent diabetes mellitus: a comparative study with purified porcine insulin. Diabetes Care 5 (1982) 73-77
-
(1982)
Diabetes Care
, vol.5
, pp. 73-77
-
-
Howley, D.C.1
Fineberg, S.E.2
Nolen, P.A.3
Stone, M.4
Gibson, R.G.5
Fineberg, N.S.6
-
49
-
-
33744984271
-
-
http://www.iddtindia.org/about.asp; http://www.geocities.com/beefandporkinsulin/Canada_NewsPage 11.html; accessed June 2005.
-
-
-
-
50
-
-
0018418005
-
Plasma kinetics and urinary excretion of exogenous human and salmon calcitonin in man
-
Huwyler R., Born W., Ohnhaus E.E., and Fischer J.A. Plasma kinetics and urinary excretion of exogenous human and salmon calcitonin in man. Am J Physiol 236 (1979) E15-E19
-
(1979)
Am J Physiol
, vol.236
-
-
Huwyler, R.1
Born, W.2
Ohnhaus, E.E.3
Fischer, J.A.4
-
51
-
-
4344584136
-
Calcitonin: physiological actions and clinical applications
-
Inzerillo A.M., Zaidi M., and Huang C.L.-H. Calcitonin: physiological actions and clinical applications. J Ped Endocrin Metab 17 (2004) 931-940
-
(2004)
J Ped Endocrin Metab
, vol.17
, pp. 931-940
-
-
Inzerillo, A.M.1
Zaidi, M.2
Huang, C.L.-H.3
-
52
-
-
0022526816
-
Can insulin antibodies of diabetic patients distinguish human insulin from porcine insulin?
-
Ishibashi O., Kobayashi M., Maegawa H., Watanabe N., Takata Y., Okuno Y., et al. Can insulin antibodies of diabetic patients distinguish human insulin from porcine insulin?. Horm Metab Res 18 (1986) 470-472
-
(1986)
Horm Metab Res
, vol.18
, pp. 470-472
-
-
Ishibashi, O.1
Kobayashi, M.2
Maegawa, H.3
Watanabe, N.4
Takata, Y.5
Okuno, Y.6
-
54
-
-
0028956430
-
Structural and conformational requirements for human calcitonin activity: design, synthesis, and study of lactam-bridged analogues
-
Kapurniotu A., and Taylor J.W. Structural and conformational requirements for human calcitonin activity: design, synthesis, and study of lactam-bridged analogues. J Med Chem 38 (1995) 836-847
-
(1995)
J Med Chem
, vol.38
, pp. 836-847
-
-
Kapurniotu, A.1
Taylor, J.W.2
-
55
-
-
17144371646
-
Effects of exenatide (exendin-4) on glycemic control over 30 weeks in patients with type 2 diabetes treated with metformin and a sulfonylurea
-
Kendall D.M., Riddle M.C., Rosenstock J., Zhuang D., Kim D.D., Fineman M.S., et al. Effects of exenatide (exendin-4) on glycemic control over 30 weeks in patients with type 2 diabetes treated with metformin and a sulfonylurea. Diabetes Care 28 (2005) 1083-1091
-
(2005)
Diabetes Care
, vol.28
, pp. 1083-1091
-
-
Kendall, D.M.1
Riddle, M.C.2
Rosenstock, J.3
Zhuang, D.4
Kim, D.D.5
Fineman, M.S.6
-
56
-
-
0038497464
-
Synthetic exendin 4 (AC2993) significantly reduces postprandial and fasting plasma glucose in subjects with type 2 diabetes
-
Kolterman O.G., Buse J.B., Fineman M.S., Gaines E., Heintz S., Bicsak T.A., et al. Synthetic exendin 4 (AC2993) significantly reduces postprandial and fasting plasma glucose in subjects with type 2 diabetes. J Clin Endocrinol Metab 88 (2003) 3082-3089
-
(2003)
J Clin Endocrinol Metab
, vol.88
, pp. 3082-3089
-
-
Kolterman, O.G.1
Buse, J.B.2
Fineman, M.S.3
Gaines, E.4
Heintz, S.5
Bicsak, T.A.6
-
57
-
-
15444367142
-
Pharmacokinetics, pharmacodynamics, and safety of exenatide in patients with type 2 diabetes mellitus
-
Kolterman O.G., Kim D.D., Shen L., Ruggles J.A., Nielsen L.L., Fineman M.S., et al. Pharmacokinetics, pharmacodynamics, and safety of exenatide in patients with type 2 diabetes mellitus. Am J Health-Syst Pharmacy 62 (2005) 173-181
-
(2005)
Am J Health-Syst Pharmacy
, vol.62
, pp. 173-181
-
-
Kolterman, O.G.1
Kim, D.D.2
Shen, L.3
Ruggles, J.A.4
Nielsen, L.L.5
Fineman, M.S.6
-
58
-
-
0036890997
-
Immune responses to therapeutic proteins in humans-clinical significance, assessment and prediction
-
Koren E., Zuckerman L.A., and Mire-Sluis A.R. Immune responses to therapeutic proteins in humans-clinical significance, assessment and prediction. Curr Pharm Biotech 3 (2002) 349-360
-
(2002)
Curr Pharm Biotech
, vol.3
, pp. 349-360
-
-
Koren, E.1
Zuckerman, L.A.2
Mire-Sluis, A.R.3
-
59
-
-
23744481594
-
Antibodies against erythropoietin and other protein-based therapeutics
-
Kromminga A., and Schellekens H. Antibodies against erythropoietin and other protein-based therapeutics. Ann N Y Acad Sci 1050 (2005) 257-265
-
(2005)
Ann N Y Acad Sci
, vol.1050
, pp. 257-265
-
-
Kromminga, A.1
Schellekens, H.2
-
60
-
-
0014216348
-
Greenwood Antibodies to corticotrophin and their relation to adrenal function in children receiving corticotrophin therapy
-
Landon J., and Friedman M. Greenwood Antibodies to corticotrophin and their relation to adrenal function in children receiving corticotrophin therapy. Lancet 1 (1967) 652
-
(1967)
Lancet
, vol.1
, pp. 652
-
-
Landon, J.1
Friedman, M.2
-
61
-
-
0023684411
-
Formation of neutralizing antibodies during intranasal synthetic salmon calcitonin treatment of Paget's disease
-
Levy F., Muff S., Dotti-Sigrist S., Dambacher M.A., and Fischer J.A. Formation of neutralizing antibodies during intranasal synthetic salmon calcitonin treatment of Paget's disease. J Clin Endocrin Metab 67 (1988) 541-545
-
(1988)
J Clin Endocrin Metab
, vol.67
, pp. 541-545
-
-
Levy, F.1
Muff, S.2
Dotti-Sigrist, S.3
Dambacher, M.A.4
Fischer, J.A.5
-
62
-
-
0035760892
-
Thrombocytopenia caused by the development of antibodies to thrombopoietin
-
Li J., Yang C., Xia Y., Bertino A., Glaspy J., Roberts M., et al. Thrombocytopenia caused by the development of antibodies to thrombopoietin. Blood 98 (2001) 3241-3248
-
(2001)
Blood
, vol.98
, pp. 3241-3248
-
-
Li, J.1
Yang, C.2
Xia, Y.3
Bertino, A.4
Glaspy, J.5
Roberts, M.6
-
63
-
-
0021215173
-
Response of Paget's disease to human calcitonin in patients resistant to porcine calcitonin
-
Lo Cascio V., Adami S., Galvanini G., Lazzaretto R., Ferrari M., Tartarotti D., et al. Response of Paget's disease to human calcitonin in patients resistant to porcine calcitonin. J Endocrinol Invest 7 (1984) 85-88
-
(1984)
J Endocrinol Invest
, vol.7
, pp. 85-88
-
-
Lo Cascio, V.1
Adami, S.2
Galvanini, G.3
Lazzaretto, R.4
Ferrari, M.5
Tartarotti, D.6
-
64
-
-
0021351108
-
Insulin antibodies in diabetic children treated with monocomponent porcine insulin from the onset: relationship to B-cell function and partial remission
-
Ludvigsson J. Insulin antibodies in diabetic children treated with monocomponent porcine insulin from the onset: relationship to B-cell function and partial remission. Diabetologia 26 (1984) 138-141
-
(1984)
Diabetologia
, vol.26
, pp. 138-141
-
-
Ludvigsson, J.1
-
65
-
-
0024272769
-
Development of insulin antibodies, metabolic control and B-cell function in newly diagnosed insulin dependent diabetic children treated with monocomponent human insulin or monocomponent porcine insulin
-
Marshall M.O., Heding L.G., Villumsen J., Akerblom H.K., Baevre H., Dahlquist G., et al. Development of insulin antibodies, metabolic control and B-cell function in newly diagnosed insulin dependent diabetic children treated with monocomponent human insulin or monocomponent porcine insulin. Diabetes Res 9 (1988) 169-175
-
(1988)
Diabetes Res
, vol.9
, pp. 169-175
-
-
Marshall, M.O.1
Heding, L.G.2
Villumsen, J.3
Akerblom, H.K.4
Baevre, H.5
Dahlquist, G.6
-
67
-
-
0018747909
-
Treatment of Paget's disease with the calcitonins
-
Martin T.J. Treatment of Paget's disease with the calcitonins. Aust N Z J Med 9 (1979) 36-43
-
(1979)
Aust N Z J Med
, vol.9
, pp. 36-43
-
-
Martin, T.J.1
-
68
-
-
0014210689
-
Antibodies and clinical resistance to parathyroid hormone
-
Melick R.A., Gill J.R., Berson S.A., Yalow R.S., Bartter F.C., Potts J.T., et al. Antibodies and clinical resistance to parathyroid hormone. N Engl J Med 276 (1967) 144
-
(1967)
N Engl J Med
, vol.276
, pp. 144
-
-
Melick, R.A.1
Gill, J.R.2
Berson, S.A.3
Yalow, R.S.4
Bartter, F.C.5
Potts, J.T.6
-
69
-
-
0041303558
-
Standardization of antibody preparations for use in immunogenicity studies: a case study using the World Health Organization International Collaborative Study for Islet Cell Antibodies
-
Mire-Sluis A., Gaines Das R., and Lernmark A. Standardization of antibody preparations for use in immunogenicity studies: a case study using the World Health Organization International Collaborative Study for Islet Cell Antibodies. Dev Biol (Basel) 112 (2003) 153-163
-
(2003)
Dev Biol (Basel)
, vol.112
, pp. 153-163
-
-
Mire-Sluis, A.1
Gaines Das, R.2
Lernmark, A.3
-
70
-
-
0026102492
-
Formation of neutralizing antibodies during intranasal synthetic salmon calcitonin treatment of postmenopausal osteoporosis
-
Muff R., Dambacher M.A., and Fischer J.A. Formation of neutralizing antibodies during intranasal synthetic salmon calcitonin treatment of postmenopausal osteoporosis. Osteoporosis Int 1 (1991) 72-75
-
(1991)
Osteoporosis Int
, vol.1
, pp. 72-75
-
-
Muff, R.1
Dambacher, M.A.2
Fischer, J.A.3
-
72
-
-
0347360186
-
Pharmacology of exenatide (synthetic exendin-4): a potential therapeutic for improved glycemic control of type 2 diabetes
-
Nielsen L.L., Young A.A., and Parkes D. Pharmacology of exenatide (synthetic exendin-4): a potential therapeutic for improved glycemic control of type 2 diabetes. Reg Pept 117 (2004) 77-88
-
(2004)
Reg Pept
, vol.117
, pp. 77-88
-
-
Nielsen, L.L.1
Young, A.A.2
Parkes, D.3
-
73
-
-
4043052238
-
Regulatory T cells and mechanisms of immune system control
-
O'Garra A., and Vieira P. Regulatory T cells and mechanisms of immune system control. Nat Med 10 (2004) 01-805
-
(2004)
Nat Med
, vol.10
, pp. 01-805
-
-
O'Garra, A.1
Vieira, P.2
-
75
-
-
0034752734
-
Pharmacokinetic actions of exendin-4 in the rat: comparison with glucagon-like peptide 1
-
Parkes D., Jodka C., Smith P., Nayak S., Rinehart L., Gingerich R., et al. Pharmacokinetic actions of exendin-4 in the rat: comparison with glucagon-like peptide 1. Drug Dev Res 53 (2001) 260-267
-
(2001)
Drug Dev Res
, vol.53
, pp. 260-267
-
-
Parkes, D.1
Jodka, C.2
Smith, P.3
Nayak, S.4
Rinehart, L.5
Gingerich, R.6
-
76
-
-
0035340019
-
Insulinotropic actions of exendin-4 and glucagon-like peptide-1 in vivo and in vitro
-
Parkes D.G., Pittner R., Jodka C., Smith P., and Young A. Insulinotropic actions of exendin-4 and glucagon-like peptide-1 in vivo and in vitro. Metabolism 50 (2001) 583-589
-
(2001)
Metabolism
, vol.50
, pp. 583-589
-
-
Parkes, D.G.1
Pittner, R.2
Jodka, C.3
Smith, P.4
Young, A.5
-
77
-
-
33745003807
-
-
Poon T, Taylor K, Nielsen L, Boies S, Zhuang D, Varns A, et al., Effects of exenatide (synthetic exendin-4) on glucose control and safety in patients with type 2 diabetes treated with metformin, a sulfonyurea, or both: an ongoing, open-label phase 3 trial. Endocr Pract 10:7 [abstract 20].
-
-
-
-
78
-
-
0014278134
-
The amino acid sequence of porcine thyrocalcitonin
-
Potts Jr. J.T., Niall Jr. H.D., Keutmann H.T., Brewer H.B., and Deftos L.J. The amino acid sequence of porcine thyrocalcitonin. Proc Natl Acad Sci 59 (1968) 1321
-
(1968)
Proc Natl Acad Sci
, vol.59
, pp. 1321
-
-
Potts Jr., J.T.1
Niall Jr., H.D.2
Keutmann, H.T.3
Brewer, H.B.4
Deftos, L.J.5
-
80
-
-
0019986237
-
Insulin antibodies induced by bovine insulin therapy
-
Reeves W.G., and Kelly U. Insulin antibodies induced by bovine insulin therapy. Clin Exp Immunol 50 (1982) 163-170
-
(1982)
Clin Exp Immunol
, vol.50
, pp. 163-170
-
-
Reeves, W.G.1
Kelly, U.2
-
81
-
-
33744997758
-
Evidence that specific antibodies do not reduce salmon calcitonin activity in vivo
-
Reginster J.Y., Almer S., Gaspar S., Collette J., Deroisy R., and Franchimont P. Evidence that specific antibodies do not reduce salmon calcitonin activity in vivo. Antibody Immunoconj Radiopharm 2 (1989) 117-124
-
(1989)
Antibody Immunoconj Radiopharm
, vol.2
, pp. 117-124
-
-
Reginster, J.Y.1
Almer, S.2
Gaspar, S.3
Collette, J.4
Deroisy, R.5
Franchimont, P.6
-
82
-
-
0027185909
-
Prevention of osteoporosis with nasal calcitonin: effect of anti-salmon calcitonin antibody formation
-
Reginster J.Y., Gaspar S., Deroisy R., Zegels B., and Franchimont P. Prevention of osteoporosis with nasal calcitonin: effect of anti-salmon calcitonin antibody formation. Osteopor Int 3 (1993) 261-264
-
(1993)
Osteopor Int
, vol.3
, pp. 261-264
-
-
Reginster, J.Y.1
Gaspar, S.2
Deroisy, R.3
Zegels, B.4
Franchimont, P.5
-
83
-
-
0036044528
-
-
Richter B, Neises G. Human versus animal insulin in people with diabetes mellitus. Cochrane Database Sys Review, J Wiley and Sons (ed); 2004. CDO03816.
-
-
-
-
84
-
-
0016274877
-
Paget's bone disease: response to human calcitonin in patients resistant to salmon calcitonin
-
Rojanasathit S., Rosenberg E., and Haddad Jr. J.G. Paget's bone disease: response to human calcitonin in patients resistant to salmon calcitonin. Lancet 2 (1974) 1412-1415
-
(1974)
Lancet
, vol.2
, pp. 1412-1415
-
-
Rojanasathit, S.1
Rosenberg, E.2
Haddad Jr., J.G.3
-
85
-
-
0343437768
-
Antibodies to human growth hormone (HGH) in human subjects treated with HGH
-
Roth J., Glick S.M., Yalow R.S., and Berson S.A. Antibodies to human growth hormone (HGH) in human subjects treated with HGH. J Clin Invest 43 (1964) 1056-1065
-
(1964)
J Clin Invest
, vol.43
, pp. 1056-1065
-
-
Roth, J.1
Glick, S.M.2
Yalow, R.S.3
Berson, S.A.4
-
86
-
-
0013921645
-
Specific antibody to vasopressin in man
-
Roth J., Glick S.M., Klein L.A., and Petersen M.J. Specific antibody to vasopressin in man. J Clin Endocrinol Metab 26 6 (1966) 671-675
-
(1966)
J Clin Endocrinol Metab
, vol.26
, Issue.6
, pp. 671-675
-
-
Roth, J.1
Glick, S.M.2
Klein, L.A.3
Petersen, M.J.4
-
87
-
-
30844473089
-
Drug-induced autoimmunity
-
Sarzi-Puttini P., Atzeni F., Capsoni F., Lubrano E., and Doria A. Drug-induced autoimmunity. Autoimunity 38 (2005) 507-518
-
(2005)
Autoimunity
, vol.38
, pp. 507-518
-
-
Sarzi-Puttini, P.1
Atzeni, F.2
Capsoni, F.3
Lubrano, E.4
Doria, A.5
-
88
-
-
0038691600
-
Immunogenicity of therapeutic proteins
-
Schellekens H. Immunogenicity of therapeutic proteins. Nephrol Dial Transplant 28 (2003) 1257-1259
-
(2003)
Nephrol Dial Transplant
, vol.28
, pp. 1257-1259
-
-
Schellekens, H.1
-
89
-
-
0042009405
-
Relationship between biopharmaceutical immunogenicity of epoetin alpha and pure red cell aplasia
-
Schellekens H. Relationship between biopharmaceutical immunogenicity of epoetin alpha and pure red cell aplasia. Curr Med Res Opin 5 (2003) 433-434
-
(2003)
Curr Med Res Opin
, vol.5
, pp. 433-434
-
-
Schellekens, H.1
-
90
-
-
3242892400
-
Immunogenicity of recombinant human proteins: causes and consequences
-
Schellekens H., and Casadevall N. Immunogenicity of recombinant human proteins: causes and consequences. J Neurol 251 Suppl. 2 (2004) 11/4-11/9
-
(2004)
J Neurol
, vol.251
, Issue.SUPPL. 2
-
-
Schellekens, H.1
Casadevall, N.2
-
91
-
-
0036598634
-
Bioequivalence and the immunogenicity of Biopharmaceuticals
-
Schellekens H. Bioequivalence and the immunogenicity of Biopharmaceuticals. Nat Rev 1 (2002) 457-462
-
(2002)
Nat Rev
, vol.1
, pp. 457-462
-
-
Schellekens, H.1
-
92
-
-
15844367464
-
Immunologic mechanisms of EPO-associated pure red cell aplasia
-
Schellekens H. Immunologic mechanisms of EPO-associated pure red cell aplasia. Best Prac Res Clin Haem 18 (2005) 473-480
-
(2005)
Best Prac Res Clin Haem
, vol.18
, pp. 473-480
-
-
Schellekens, H.1
-
93
-
-
0027519426
-
Immunogenicity and allergenic potential of animal and human insulins
-
Schernthaner G. Immunogenicity and allergenic potential of animal and human insulins. Diabetes Care 16 (1993) 155-165
-
(1993)
Diabetes Care
, vol.16
, pp. 155-165
-
-
Schernthaner, G.1
-
94
-
-
0000385121
-
Katschinski Exendin (9-39)amide is an antagonist of glucagons-like peptide-1(7-36) amide in humans
-
Schirra J., Sturm K., Leicht P., Arnold R., and Goke B. Katschinski Exendin (9-39)amide is an antagonist of glucagons-like peptide-1(7-36) amide in humans. J Clin Invest 101 (1998) 1421-1430
-
(1998)
J Clin Invest
, vol.101
, pp. 1421-1430
-
-
Schirra, J.1
Sturm, K.2
Leicht, P.3
Arnold, R.4
Goke, B.5
-
95
-
-
0015388687
-
An evaluation of antibodies and clinical resistance to salmon calcitonin
-
Singer F.R., Aldred J.P., Neer M., Krane S.M., Potts J.T., and Bloch K.J. An evaluation of antibodies and clinical resistance to salmon calcitonin. J Clin Invest 51 (1972) 2231-2238
-
(1972)
J Clin Invest
, vol.51
, pp. 2231-2238
-
-
Singer, F.R.1
Aldred, J.P.2
Neer, M.3
Krane, S.M.4
Potts, J.T.5
Bloch, K.J.6
-
96
-
-
0018954326
-
Salmon calcitonin therapy for Paget's disease of bone. The problem of acquired clinical resistance
-
Singer F.R., Fredericks R.S., and Minkin C. Salmon calcitonin therapy for Paget's disease of bone. The problem of acquired clinical resistance. Arthritis Rheum 23 (1980) 1148-1153
-
(1980)
Arthritis Rheum
, vol.23
, pp. 1148-1153
-
-
Singer, F.R.1
Fredericks, R.S.2
Minkin, C.3
-
97
-
-
0026075840
-
Clinical efficacy of salmon calcitonin in Paget's disease of bone
-
Singer F.R. Clinical efficacy of salmon calcitonin in Paget's disease of bone. Calcif Tissue Int 49 (1991) S7-S8
-
(1991)
Calcif Tissue Int
, vol.49
-
-
Singer, F.R.1
-
98
-
-
0013910650
-
Species variation in the amino acid sequence of insulin
-
Smith L.F. Species variation in the amino acid sequence of insulin. Am J Med 40 (1966) 662-666
-
(1966)
Am J Med
, vol.40
, pp. 662-666
-
-
Smith, L.F.1
-
99
-
-
0026011528
-
Loss of interferon antibodies during prolonged continuous interferon-alpha 2a therapy in hairy cell leukemia
-
Steis R.G., Smith II J.W., Urba W.J., Venzon D.J., Longo D.L., Barney R., et al. Loss of interferon antibodies during prolonged continuous interferon-alpha 2a therapy in hairy cell leukemia. Blood 77 (1991) 792-798
-
(1991)
Blood
, vol.77
, pp. 792-798
-
-
Steis, R.G.1
Smith II, J.W.2
Urba, W.J.3
Venzon, D.J.4
Longo, D.L.5
Barney, R.6
-
100
-
-
0034456212
-
-
Szayna M, Doyle ME, Betkey JA, Holloway HW, Spencer RGS, Greig NH, et al., Exendin-4 decelerates food intake, weight gain, and fat deposition in Zucker rats. Endocrinol 200; 141: 1936-1941.
-
-
-
-
101
-
-
0024418768
-
Clinical significance of insulin antibodies in insulin-treated patients
-
Van Haeften T.W. Clinical significance of insulin antibodies in insulin-treated patients. Diabetes Care 9 (1989) 641-648
-
(1989)
Diabetes Care
, vol.9
, pp. 641-648
-
-
Van Haeften, T.W.1
-
102
-
-
0020419292
-
Insulin-specific IgG and IgE antibody response in type 1 diabetic subjects exclusively treated with human insulin (recombinant DNA)
-
Velcovsky H.G., and Federlin K.F. Insulin-specific IgG and IgE antibody response in type 1 diabetic subjects exclusively treated with human insulin (recombinant DNA). Diabetes Care 5 (1982) 126-128
-
(1982)
Diabetes Care
, vol.5
, pp. 126-128
-
-
Velcovsky, H.G.1
Federlin, K.F.2
-
103
-
-
0142039654
-
Strategies for detection, measurement and characterization of unwanted antibodies induced by therapeutic biologicals
-
Wadhwa M., Bird C., Dilger P., Gaines-Das R., and Thorpe R. Strategies for detection, measurement and characterization of unwanted antibodies induced by therapeutic biologicals. J Immunol Methods 278 (2003) 1-17
-
(2003)
J Immunol Methods
, vol.278
, pp. 1-17
-
-
Wadhwa, M.1
Bird, C.2
Dilger, P.3
Gaines-Das, R.4
Thorpe, R.5
-
104
-
-
0020070613
-
The effect of insulin antibodies on insulin dose and diabetic control
-
Walford S., Allison S.P., and Reeves W.G. The effect of insulin antibodies on insulin dose and diabetic control. Diabetologia 22 (1982) 106-110
-
(1982)
Diabetologia
, vol.22
, pp. 106-110
-
-
Walford, S.1
Allison, S.P.2
Reeves, W.G.3
-
105
-
-
0017703657
-
Development and significance of antibodies to salmon calcitonin in patients with Paget's disease on long-term administration
-
Woodhouse N.J.Y., Mohamedally S.M., Saed-Nejad F., and Martin T.J. Development and significance of antibodies to salmon calcitonin in patients with Paget's disease on long-term administration. Br Med J 2 (1977) 927-929
-
(1977)
Br Med J
, vol.2
, pp. 927-929
-
-
Woodhouse, N.J.Y.1
Mohamedally, S.M.2
Saed-Nejad, F.3
Martin, T.J.4
-
106
-
-
0032908654
-
Glucose-lowering and insulin-sensitizing actions of exendin-4: studies in obese diabetic (ob/ob, db/db) mice, diabetic fatty Zucker rats, and diabetic rhesus monkeys (Macaca mulatta)
-
Young A.A., Gedulin B.R., Bhavsar S., Bodkin N., Jodka C., Hansen B., et al. Glucose-lowering and insulin-sensitizing actions of exendin-4: studies in obese diabetic (ob/ob, db/db) mice, diabetic fatty Zucker rats, and diabetic rhesus monkeys (Macaca mulatta). Diabetes 48 (1999) 1026-1034
-
(1999)
Diabetes
, vol.48
, pp. 1026-1034
-
-
Young, A.A.1
Gedulin, B.R.2
Bhavsar, S.3
Bodkin, N.4
Jodka, C.5
Hansen, B.6
-
107
-
-
0036951194
-
Calcitonin and bone formation: a knockout full of surprises
-
Zaidi M., Moonga B.S., and Abe E. Calcitonin and bone formation: a knockout full of surprises. J Clin Invest 110 (2002) 1769-1771
-
(2002)
J Clin Invest
, vol.110
, pp. 1769-1771
-
-
Zaidi, M.1
Moonga, B.S.2
Abe, E.3
|