Bag1 is a regulator and marker of neuronal differentiation

Cell Death and Differentiation

Volumn 9, Issue 4, 2002, Pages 405-413

  Kermer, P ^a   Krajewska, M ^a   Zapata, J M ^a   Takayama, S ^a   Mai, J ^a,b   Krajewski, S ^a   Reed, J C ^a  

^a BURNHAM INSTITUTE   (United States)

^b HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

Apoptosis; Bag1; CSM 14.1 cells; Mouse brain development; Neuronal differentiation; Neuroprotection

Indexed keywords

BAG1 PROTEIN; BIOLOGICAL MARKER; CHAPERONE; HEAT SHOCK PROTEIN 70; MITOGEN ACTIVATED PROTEIN KINASE; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; CELL DEATH; CELL IMMORTALIZATION; CELL MIGRATION; CELL NUCLEUS; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; CYTOSOL; EMBRYO; GENE OVEREXPRESSION; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NERVE CELL DIFFERENTIATION; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; SERUM; STEM CELL;

ANIMALS; BIOLOGICAL MARKERS; CELL DEATH; CELL DIFFERENTIATION; CELL LINE; CULTURE MEDIA; DNA-BINDING PROTEINS; MAP KINASE SIGNALING SYSTEM; MEMBRANE PROTEINS; MICE; NERVOUS SYSTEM; NEURONS; TRANSCRIPTION FACTORS;

ANIMALIA;

EID: 0036312350     PISSN: 13509047     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cdd.4400972     Document Type: Article

References (35)

1. Cloning and functional analysis of Bag-1: A novel Bcl-2 binding protein with anti-cell death activity
2. An evolutionarily conserved family of Hsp70/Hsc70 molecular chaperone regulators
3. Molecular chaperone targeting and regulation by BAG family proteins
4. A protein that interacts with members of the nuclear hormone receptor family: Identification and cDNA cloning
5. HGF receptor associates with the anti-apoptotic protein BAG-1 and prevents cell death
6. Bcl-2 interacting protein, BAG-1, binds to and activates the kinase Raf-1
7. Role of Bag-1 in the survival and proliferation of the cytokine-dependent lympocyte lines, Ba/F3 and Nb2
8. BAG-1 inhibits p53-induced but not apoptin-induced apoptosis
9. Cooperative interception of neuronal apoptosis by BCL-2 and BAG-1 expression: Prevention of caspase activation and reduced production of reactive oxygen species
10. Anti-cell death activity promotes pulmonary metastasis of melanoma cells
11. Interaction of BAG-1 with retinoic acid receptor and its inhibition of retinoic acid-induced apoptosis in cancer cells
12. RAP46 is a negative regulator of glucocorticoid receptor action and hormone induced apoptosis
13. p53-inducible human homologue of Drosophila seven in absentia (Siah) inhibits cell growth: Suppression by BAG-1
14. BAG-1L protein enhances androgen receptor function
15. The neuropeptide potential of heat shock protein 70 (HSP70)
16. Heat-shock protein protection
17. BAG-1 modulates the chaperone activity of Hsp70/Hsc70
18. Isoform-specific expression of BAG-1 in mouse development
19. Synergistic effect of Bcl-1 and BAG-1 on the prevention of photoreceptor cell death
20. Loss of bag-1 immunoreactivity in rat brain after transient middle cerebral artery occlusion
21. Alteration of the stability of Bag-1 protein in the control of olfactory neuronal apoptosis
22. Expression and location of Hsp70/Hsc-binding anti-apoptotic protein BAG-1 and its variants in normal tissues and tumor cell lines
23. Bcl-2 inhibits death of central neural cells induced by multiple agents
24. Transgenic mice expressing beta-galactosidase in mature neurons under neuron-specific enolase promoter control
25. Bag-1 and Bcl-2 gene transfer in malignant glioma: Modulation of cell cycle regulation and apoptosis
26. The complexity of Raf-1 regulation
27. Bag1-Hsp70 mediates a physiological stress signaling pathway that regulates Raf-21/ERK and cell growth
28. Ras activation of the Raf kinase: Tyrosine kinase recruitment of the MAP kinase cascade
29. The neuronal MAP kinase cascade: A biochemical signal integration system subserving synaptic plasticity and memory
30. Isolation of 10 differentially expressed cDNAs in p53-induced apoptosis: Activation of the vertebrate homologue of the Drosphilia seven in absentia gene
31. Analysis of the p53 gene and its expression in human glioblastoma cells
32. Bag1 functions in vivo as a negative regulator of Hsp70 chaperone activity
33. Immunohistochemical determination of in vivo distribution of bax, a dominant inhibitor of Bcl-2
34. Upregulation of Bax protein levels in neurons following cerebral ischemia
35. Release of caspase-9 from mitochondria during neuronal apoptosis and cerebral ischemia