메뉴 건너뛰기




Volumn 20, Issue 3, 2006, Pages 167-179

New pharmacologic approaches to therapy for age-related macular degeneration

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ALPHA TOCOPHEROL; ANECORTAVE; ASCORBIC ACID; BETA CAROTENE; BEVACIZUMAB; COPPER; CORTICOSTEROID; DORZOLAMIDE; FLAVONOID; GENISTEIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; MATRIX METALLOPROTEINASE; METHOTREXATE; PEGAPTANIB; PIGMENT EPITHELIUM DERIVED FACTOR; POLYPHENOL; PROSTAGLANDIN SYNTHASE INHIBITOR; RANIBIZUMAB; SMALL INTERFERING RNA; SQUALAMINE; TRIAMCINOLONE; VASCULOTROPIN; XANTHOPHYLL; ZEAXANTHIN; ZINC;

EID: 33744935522     PISSN: 11738804     EISSN: 11738804     Source Type: Journal    
DOI: 10.2165/00063030-200620030-00004     Document Type: Review
Times cited : (41)

References (119)
  • 1
    • 0029691499 scopus 로고    scopus 로고
    • Age-related macular disease
    • Bird A. Age-related macular disease. Br J Ophthalmol 1996; 80 (1): 2-3
    • (1996) Br J Ophthalmol , vol.80 , Issue.1 , pp. 2-3
    • Bird, A.1
  • 2
    • 4243189709 scopus 로고    scopus 로고
    • Clinical manifestations
    • Holz FG, Pauleikhoff D, Spaide RF, et al., editors. Berlin: Springer
    • Holz FG, Pauleikhoff D. Clinical manifestations. In: Holz FG, Pauleikhoff D, Spaide RF, et al., editors. Age-related macular degeneration. Berlin: Springer, 2004: 73-90
    • (2004) Age-related Macular Degeneration , pp. 73-90
    • Holz, F.G.1    Pauleikhoff, D.2
  • 3
    • 0033795036 scopus 로고    scopus 로고
    • The role of oxidative stress in the pathogenesis of age-related macular degeneration
    • Beatty S, Koh H, Phil M, et al. The role of oxidative stress in the pathogenesis of age-related macular degeneration. Surv Ophthalmol 2000; 45 (2): 115-34
    • (2000) Surv Ophthalmol , vol.45 , Issue.2 , pp. 115-134
    • Beatty, S.1    Koh, H.2    Phil, M.3
  • 4
    • 0033499606 scopus 로고    scopus 로고
    • Characterization of peroxidized lipids in Bruch's membrane
    • Spaide RF, Ho-Spaide WC, Browne RW, et al. Characterization of peroxidized lipids in Bruch's membrane. Retina 1999; 19 (2): 141-7
    • (1999) Retina , vol.19 , Issue.2 , pp. 141-147
    • Spaide, R.F.1    Ho-Spaide, W.C.2    Browne, R.W.3
  • 5
  • 6
    • 0023244977 scopus 로고
    • Zur Therapie der degenerativen Makulopathie mit Cosaldon A + E
    • Flamm P. Zur Therapie der degenerativen Makulopathie mit Cosaldon A + E. Klin Monatsbl Augenheilkd 1987; 190 (1): 59-66
    • (1987) Klin Monatsbl Augenheilkd , vol.190 , Issue.1 , pp. 59-66
    • Flamm, P.1
  • 7
    • 0019932646 scopus 로고
    • Zinc in the eye
    • Karcioglu Z. Zinc in the eye. Surv Ophthalmol 1982; 27: 114-22
    • (1982) Surv Ophthalmol , vol.27 , pp. 114-122
    • Karcioglu, Z.1
  • 8
  • 9
    • 0027767248 scopus 로고
    • Evaluation of dietary antioxidant levels and supplementation with ICAPS-Plus and Ocuvite
    • Kaminski MS, Yolton DP, Jordan WT, et al. Evaluation of dietary antioxidant levels and supplementation with ICAPS-Plus and Ocuvite. J Am Optom Assoc 1993; 64 (12): 862-70
    • (1993) J Am Optom Assoc , vol.64 , Issue.12 , pp. 862-870
    • Kaminski, M.S.1    Yolton, D.P.2    Jordan, W.T.3
  • 10
    • 2942692492 scopus 로고
    • Oral zinc-therapy in age-related macular degeneration: A double blind study
    • Holz FG, Wolfensberger TJ, Piguet B, et al. Oral zinc-therapy in age-related macular degeneration: a double blind study. Ger J Ophthalmol 1993; 2 Suppl. 2: 391
    • (1993) Ger J Ophthalmol , vol.2 , Issue.2 SUPPL. , pp. 391
    • Holz, F.G.1    Wolfensberger, T.J.2    Piguet, B.3
  • 11
    • 0037880734 scopus 로고    scopus 로고
    • Anti-vascular endothelial growth factor therapy for subfoveal choroidal neovascularization secondary to age-related macular degeneration: Phase II study results
    • The Eyetech Study Group. Anti-vascular endothelial growth factor therapy for subfoveal choroidal neovascularization secondary to age-related macular degeneration: phase II study results. Ophthalmol 2003; 110: 979-86
    • (2003) Ophthalmol , vol.110 , pp. 979-986
  • 12
    • 0034800655 scopus 로고    scopus 로고
    • A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8
    • The AREDS Study Group. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8. Arch Ophthalmol 2001; 119 (10): 1417-36
    • (2001) Arch Ophthalmol , vol.119 , Issue.10 , pp. 1417-1436
  • 13
    • 0036527505 scopus 로고    scopus 로고
    • Vitamine und Spurenelemente bei altersabhängiger Makuladegeneration. Aktuelle Empfehlungen, basierend auf den Resultaten der AREDS-Studie
    • Schutt F, Pauleikhoff D, Holz FG. Vitamine und Spurenelemente bei altersabhängiger Makuladegeneration. Aktuelle Empfehlungen, basierend auf den Resultaten der AREDS-Studie. Ophthalmologe 2002; 99: 301-3
    • (2002) Ophthalmologe , vol.99 , pp. 301-303
    • Schutt, F.1    Pauleikhoff, D.2    Holz, F.G.3
  • 14
    • 0036295596 scopus 로고    scopus 로고
    • AREDS investigators distort findings
    • Seigel D. AREDS investigators distort findings. Arch Ophthalmol 2002; 120 (1): 100-1
    • (2002) Arch Ophthalmol , vol.120 , Issue.1 , pp. 100-101
    • Seigel, D.1
  • 15
    • 0029955507 scopus 로고    scopus 로고
    • Beta-carotene increases lung cancer incidence in cigarette smokers
    • Jun
    • De Luca LM, Ross SA. Beta-carotene increases lung cancer incidence in cigarette smokers. Nutr Rev 1996 Jun; 54 (6): 178-80
    • (1996) Nutr Rev , vol.54 , Issue.6 , pp. 178-180
    • De Luca, L.M.1    Ross, S.A.2
  • 16
    • 0036556473 scopus 로고    scopus 로고
    • Critical comments on the ARED study
    • Augustin AJ, Schmidt-Erfurth U. Critical comments on the ARED study [in German]. Ophthalmologe 2002; 99 (4): 299-300
    • (2002) Ophthalmologe , vol.99 , Issue.4 , pp. 299-300
    • Augustin, A.J.1    Schmidt-Erfurth, U.2
  • 17
    • 0034945089 scopus 로고    scopus 로고
    • Makul̈ares pigment und altersabhängige makuladegeneration
    • Pauleikhoff D, van Kuijk FJ, Bird AC. Makul̈ares pigment und altersabhängige makuladegeneration. Ophthalmologe 2001; 98: 511-9
    • (2001) Ophthalmologe , vol.98 , pp. 511-519
    • Pauleikhoff, D.1    Van Kuijk, F.J.2    Bird, A.C.3
  • 18
    • 0034098106 scopus 로고    scopus 로고
    • Macular pigment optical density in a Southwestern sample
    • Hammond B, Caruso-Avery M. Macular pigment optical density in a Southwestern sample. Invest Ophthalmol Vis Sci 2000; 41 (6): 1492-7
    • (2000) Invest Ophthalmol Vis Sci , vol.41 , Issue.6 , pp. 1492-1497
    • Hammond, B.1    Caruso-Avery, M.2
  • 19
    • 0035142770 scopus 로고    scopus 로고
    • Macular pigment and risk for age-related macular degeneration in subjects from a Northern European population
    • Beatty S, Murray IJ, Henson DB, et al. Macular pigment and risk for age-related macular degeneration in subjects from a Northern European population. Invest Ophthalmol Vis Sci 2001; 42 (2): 439-46
    • (2001) Invest Ophthalmol Vis Sci , vol.42 , Issue.2 , pp. 439-446
    • Beatty, S.1    Murray, I.J.2    Henson, D.B.3
  • 21
    • 0033775205 scopus 로고    scopus 로고
    • Influence of lutein supplementation on macular pigment, assessed with two objective techniques
    • Berendschot TT, Goldbohm RA, Klopping WA, et al. Influence of lutein supplementation on macular pigment, assessed with two objective techniques. Invest Ophthalmol Vis Sci 2000; 41 (11): 3322-6
    • (2000) Invest Ophthalmol Vis Sci , vol.41 , Issue.11 , pp. 3322-3326
    • Berendschot, T.T.1    Goldbohm, R.A.2    Klopping, W.A.3
  • 22
    • 0030752005 scopus 로고    scopus 로고
    • A one year study of the macular pigment: The effect of 140 days of a lutein supplement
    • Landrum JT, Bone RA, Joa H, et al. A one year study of the macular pigment: the effect of 140 days of a lutein supplement. Exp Eye Res 1997; 65 (1): 57-62
    • (1997) Exp Eye Res , vol.65 , Issue.1 , pp. 57-62
    • Landrum, J.T.1    Bone, R.A.2    Joa, H.3
  • 23
    • 0345269950 scopus 로고    scopus 로고
    • Lutein and zeaxanthin dietary supplements raise macular pigment density and serum concentrations of these carotenoids in humans
    • Bone RA, Landrum JT, Guerra LH, et al. Lutein and zeaxanthin dietary supplements raise macular pigment density and serum concentrations of these carotenoids in humans. J Nutr 2003; 133 (4): 992-8
    • (2003) J Nutr , vol.133 , Issue.4 , pp. 992-998
    • Bone, R.A.1    Landrum, J.T.2    Guerra, L.H.3
  • 24
    • 0037224777 scopus 로고    scopus 로고
    • Influence of short-term antioxidant supplementation on macular function in age-related maculopathy: A pilot study including electrophysiologic assessment
    • Falsini B, Piccardi M, Iarossi G, et al. Influence of short-term antioxidant supplementation on macular function in age-related maculopathy: a pilot study including electrophysiologic assessment. Ophthalmology 2003; 110 (1): 51-60
    • (2003) Ophthalmology , vol.110 , Issue.1 , pp. 51-60
    • Falsini, B.1    Piccardi, M.2    Iarossi, G.3
  • 25
    • 33744905897 scopus 로고    scopus 로고
    • Future clinical trials: AREDS II with lutein/zeaxanthin
    • E-abstract 1228
    • Ey C. Future clinical trials: AREDS II with lutein/zeaxanthin [E-abstract 1228]. Ophthalmol Vis Sci 2005; 46 Suppl.
    • (2005) Ophthalmol Vis Sci , vol.46 , Issue.SUPPL.
    • Ey, C.1
  • 26
    • 0033050396 scopus 로고    scopus 로고
    • Inhibition of choriocapillaris regeneration with genistein
    • Majji AB, Hayashi A, Kim HC, et al. Inhibition of choriocapillaris regeneration with genistein. Invest Ophthalmol Vis Sci 1999; 40 (7): 1477-86
    • (1999) Invest Ophthalmol Vis Sci , vol.40 , Issue.7 , pp. 1477-1486
    • Majji, A.B.1    Hayashi, A.2    Kim, H.C.3
  • 27
    • 0034908730 scopus 로고    scopus 로고
    • Normalization of retinal vascular permeability in experimental diabetes with genistein
    • Nakajima M, Cooney MJ, Tu AH, et al. Normalization of retinal vascular permeability in experimental diabetes with genistein. Invest Ophthalmol Vis Sci 2001; 42 (9): 2110-4
    • (2001) Invest Ophthalmol Vis Sci , vol.42 , Issue.9 , pp. 2110-2114
    • Nakajima, M.1    Cooney, M.J.2    Tu, A.H.3
  • 28
    • 0029166407 scopus 로고
    • Angiogenic factors stimulate mast-cell migration
    • Gruber BL, Marchese MJ, Kew R. Angiogenic factors stimulate mast-cell migration. Blood 1995; 86 (7): 2488-93
    • (1995) Blood , vol.86 , Issue.7 , pp. 2488-2493
    • Gruber, B.L.1    Marchese, M.J.2    Kew, R.3
  • 29
    • 0028895694 scopus 로고
    • Genistein, a dietary ingested isoflavonoid, inhibits cell proliferation and in vitro angiogenesis
    • Fotsis T, Pepper M, Adlercreutz H, et al. Genistein, a dietary ingested isoflavonoid, inhibits cell proliferation and in vitro angiogenesis. J Nutr 1995; 125 (3 Suppl.): 790-7
    • (1995) J Nutr , vol.125 , Issue.3 SUPPL. , pp. 790-797
    • Fotsis, T.1    Pepper, M.2    Adlercreutz, H.3
  • 30
    • 0033833611 scopus 로고    scopus 로고
    • The second eye of Japanese patients with unilateral exudative age related macular degeneration
    • Sep
    • Uyama M, Takahashi K, Ida N, et al. The second eye of Japanese patients with unilateral exudative age related macular degeneration. Br J Ophthalmol 2000 Sep; 84 (9): 1018-23
    • (2000) Br J Ophthalmol , vol.84 , Issue.9 , pp. 1018-1023
    • Uyama, M.1    Takahashi, K.2    Ida, N.3
  • 31
    • 0032692874 scopus 로고    scopus 로고
    • Age-related macular degeneration in Chinese-Canadians
    • Aug
    • Chang TS, Hay D, Courtright P. Age-related macular degeneration in Chinese-Canadians. Can J Ophthalmol 1999 Aug; 34 (5): 266-71
    • (1999) Can J Ophthalmol , vol.34 , Issue.5 , pp. 266-271
    • Chang, T.S.1    Hay, D.2    Courtright, P.3
  • 32
    • 1842451938 scopus 로고    scopus 로고
    • Statin and aspirin therapy are associated with decreased rates of choroidal neovascularization among patients with age-related macular degeneration
    • Wilson HL, Schwartz DM, Bhatt HR, et al. Statin and aspirin therapy are associated with decreased rates of choroidal neovascularization among patients with age-related macular degeneration. Am J Ophthalmol 2004; 137 (4): 615-24
    • (2004) Am J Ophthalmol , vol.137 , Issue.4 , pp. 615-624
    • Wilson, H.L.1    Schwartz, D.M.2    Bhatt, H.R.3
  • 33
    • 0037213039 scopus 로고    scopus 로고
    • Anti-inflammatory and immunomodulatory effects of statins
    • Blanco-Colio LM, Tunon J, Martin-Ventura JL, et al. Anti-inflammatory and immunomodulatory effects of statins. Kidney Int 2003; 63 (1): 12-23
    • (2003) Kidney Int , vol.63 , Issue.1 , pp. 12-23
    • Blanco-Colio, L.M.1    Tunon, J.2    Martin-Ventura, J.L.3
  • 34
    • 0036867764 scopus 로고    scopus 로고
    • Statins: The new aspirin?
    • Veillard N, Mach F. Statins: the new aspirin? Cell Mol Life Sci 2002; 51: 1771-86
    • (2002) Cell Mol Life Sci , vol.51 , pp. 1771-1786
    • Veillard, N.1    Mach, F.2
  • 35
    • 0026439413 scopus 로고
    • Risk factors for neovascular age-related macular degeneration
    • The Eye Disease Case-Control Study Group. Risk factors for neovascular age-related macular degeneration. Arch Ophthalmol 1992; 110 (12): 1701-8
    • (1992) Arch Ophthalmol , vol.110 , Issue.12 , pp. 1701-1708
  • 36
    • 28444468904 scopus 로고    scopus 로고
    • Esterified and unesterified cholesterol in drusen and basal deposits of eyes with age-related maculopathy
    • Dec
    • Curcio CA, Presley JB, Malek G, et al. Esterified and unesterified cholesterol in drusen and basal deposits of eyes with age-related maculopathy. Exp Eye Res 2005 Dec; 81 (6): 731-41
    • (2005) Exp Eye Res , vol.81 , Issue.6 , pp. 731-741
    • Curcio, C.A.1    Presley, J.B.2    Malek, G.3
  • 37
    • 0037332052 scopus 로고    scopus 로고
    • Apolipoprotein B in cholesterol-containing drusen and basal deposits of human eyes with age-related maculopathy
    • Feb
    • Malek G, Li CM, Guidry C, et al. Apolipoprotein B in cholesterol- containing drusen and basal deposits of human eyes with age-related maculopathy. Am J Pathol 2003 Feb; 162 (2): 413-25
    • (2003) Am J Pathol , vol.162 , Issue.2 , pp. 413-425
    • Malek, G.1    Li, C.M.2    Guidry, C.3
  • 38
    • 0035173704 scopus 로고    scopus 로고
    • Accumulation of cholesterol with age in human Bruch's membrane
    • Jan
    • Curcio CA, Millican CL, Bailey T, et al. Accumulation of cholesterol with age in human Bruch's membrane. Invest Ophthalmol Vis Sci 2001 Jan; 42 (1): 265-74
    • (2001) Invest Ophthalmol Vis Sci , vol.42 , Issue.1 , pp. 265-274
    • Curcio, C.A.1    Millican, C.L.2    Bailey, T.3
  • 39
    • 0035173704 scopus 로고    scopus 로고
    • Accumulation of cholesterol with age in human Bruch's membrane
    • Curcio CA, Millican CL, Bailey T, et al. Accumulation of cholesterol with age in human Bruch's membrane. Invest Ophthalmol Vis Sci 2001; 42 (1): 265-74
    • (2001) Invest Ophthalmol Vis Sci , vol.42 , Issue.1 , pp. 265-274
    • Curcio, C.A.1    Millican, C.L.2    Bailey, T.3
  • 40
    • 0035908795 scopus 로고    scopus 로고
    • Risk of macular degeneration in users of statins: Cross sectional study
    • Hall NF, Gale CR, Syddall H, et al. Risk of macular degeneration in users of statins: cross sectional study. BMJ 2001; 323: 375-6
    • (2001) BMJ , vol.323 , pp. 375-376
    • Hall, N.F.1    Gale, C.R.2    Syddall, H.3
  • 41
    • 32844473371 scopus 로고    scopus 로고
    • Inhibition of VEGF-induced endothelial cell proliferation and differentiation by steroidal and non-steroidal COX inhibitors with variable COX-1/COX-2 selectivity
    • E-abstract 1914
    • Yang R, McCollum G, Bingaman D, et al. Inhibition of VEGF-induced endothelial cell proliferation and differentiation by steroidal and non-steroidal COX inhibitors with variable COX-1/COX-2 selectivity [E-abstract 1914]. Invest Ophthalmol Vis Sci 2004; 45 Suppl.
    • (2004) Invest Ophthalmol Vis Sci , vol.45 , Issue.SUPPL.
    • Yang, R.1    McCollum, G.2    Bingaman, D.3
  • 42
    • 33744909210 scopus 로고    scopus 로고
    • Phase II trial of celebrex in photodynamic therapy (C-PDT) for neovascular age-related macular degeneration (AMD): Rationale and baseline characteristics
    • E-abstract 1186
    • Csaky KG. Phase II trial of celebrex in photodynamic therapy (C-PDT) for neovascular age-related macular degeneration (AMD): rationale and baseline characteristics [E-abstract 1186]. Invest Ophthalmol Vis Sci 2004; 45 Suppl.
    • (2004) Invest Ophthalmol Vis Sci , vol.45 , Issue.SUPPL.
    • Csaky, K.G.1
  • 43
    • 17144433662 scopus 로고    scopus 로고
    • Changes in choriocapillaris and retinal pigment epithelium in age-related macular degeneration
    • Lutty G, Grunwald J, Majji AB, et al. Changes in choriocapillaris and retinal pigment epithelium in age-related macular degeneration. Mol Vis 1999; 5: 35
    • (1999) Mol Vis , vol.5 , pp. 35
    • Lutty, G.1    Grunwald, J.2    Majji, A.B.3
  • 44
    • 0034908261 scopus 로고    scopus 로고
    • Age-related maculopathy in a randomized trial of low-dose aspirin among US physicians
    • Christen WG, Glynn RJ, Ajani UA, et al. Age-related maculopathy in a randomized trial of low-dose aspirin among US physicians. Arch Ophthalmol 2001; 119 (8): 1143-9
    • (2001) Arch Ophthalmol , vol.119 , Issue.8 , pp. 1143-1149
    • Christen, W.G.1    Glynn, R.J.2    Ajani, U.A.3
  • 45
    • 0023813198 scopus 로고
    • Factors associated with age-related macular degeneration: An analysis of data from the first National Health and Nutrition Examination Survey
    • Goldberg J, Flowerdew G, Smith E, et al. Factors associated with age-related macular degeneration: an analysis of data from the first National Health and Nutrition Examination Survey. Am J Epidemiol 1988; 128 (4): 700-10
    • (1988) Am J Epidemiol , vol.128 , Issue.4 , pp. 700-710
    • Goldberg, J.1    Flowerdew, G.2    Smith, E.3
  • 46
    • 0142165030 scopus 로고    scopus 로고
    • The mechanism of action of aspirin
    • Vane JR, Botting RM. The mechanism of action of aspirin. Thromb Res 2003; 110 (5-6): 255-8
    • (2003) Thromb Res , vol.110 , Issue.5-6 , pp. 255-258
    • Vane, J.R.1    Botting, R.M.2
  • 47
    • 0038694680 scopus 로고    scopus 로고
    • The effects of dorzolamide on choroidal and retinal perfusion in non-exudative age related macular degeneration
    • Harris A, Ciulla TA, Pratt LM, et al. The effects of dorzolamide on choroidal and retinal perfusion in non-exudative age related macular degeneration. Br J Ophthalmol 2003; 87 (6): 753-7
    • (2003) Br J Ophthalmol , vol.87 , Issue.6 , pp. 753-757
    • Harris, A.1    Ciulla, T.A.2    Pratt, L.M.3
  • 48
    • 0025058674 scopus 로고
    • Choroidal perfusion abnormality with age-related Bruch's membrane change
    • Pauleikhoff D, Chen JC, Chisholm IH, et al. Choroidal perfusion abnormality with age-related Bruch's membrane change. Am J Ophthalmol 1990; 109 (2): 211-7
    • (1990) Am J Ophthalmol , vol.109 , Issue.2 , pp. 211-217
    • Pauleikhoff, D.1    Chen, J.C.2    Chisholm, I.H.3
  • 49
    • 0016007951 scopus 로고
    • Tumor angiogenesis
    • Folkman J. Tumor angiogenesis. Adv Cancer Res 1974; 19: 331-58
    • (1974) Adv Cancer Res , vol.19 , pp. 331-358
    • Folkman, J.1
  • 50
    • 0344468927 scopus 로고
    • Inhibition of VEGF prevents ocular neovascularization in a monkey model
    • Miller J, Shima DT, Tolentino M, et al. Inhibition of VEGF prevents ocular neovascularization in a monkey model [abstract]. Invest Ophthalmol Vis Sci 1995; 36: 401
    • (1995) Invest Ophthalmol Vis Sci , vol.36 , pp. 401
    • Miller, J.1    Shima, D.T.2    Tolentino, M.3
  • 51
    • 0033882695 scopus 로고    scopus 로고
    • Overexpression of vascular endothelial growth factor (VEGF) in the retinal pigment epithelium leads to the development of choroidal neovascularization
    • Spilsbury K, Garrett KL, Shen WY, et al. Overexpression of vascular endothelial growth factor (VEGF) in the retinal pigment epithelium leads to the development of choroidal neovascularization. Am J Pathol 2000; 157 (1): 135-44
    • (2000) Am J Pathol , vol.157 , Issue.1 , pp. 135-144
    • Spilsbury, K.1    Garrett, K.L.2    Shen, W.Y.3
  • 52
    • 0017656488 scopus 로고
    • Aussichten und Grenzen der Behandlung seniler Makulopathien mit Phosphatiden
    • Hruby K. Aussichten und Grenzen der Behandlung seniler Makulopathien mit Phosphatiden. Wien Klin Wochenschr 1977; 89 (13): 439-42
    • (1977) Wien Klin Wochenschr , vol.89 , Issue.13 , pp. 439-442
    • Hruby, K.1
  • 53
    • 0035407426 scopus 로고    scopus 로고
    • In vivo use of oligonucleotides to inhibit choroidal neovascularization in the eye
    • Garrett K, Shen WY, Rakoczy PE. In vivo use of oligonucleotides to inhibit choroidal neovascularization in the eye. J Gene Med 2001; 3: 373-83
    • (2001) J Gene Med , vol.3 , pp. 373-383
    • Garrett, K.1    Shen, W.Y.2    Rakoczy, P.E.3
  • 54
    • 11144239923 scopus 로고    scopus 로고
    • Pegaptanib for neovascular age-related macular degeneration
    • Gragoudas ES, Adamis AP, Cunningham Jr ET, et al. Pegaptanib for neovascular age-related macular degeneration. N Engl J Med 2004; 351 (27): 2805-16
    • (2004) N Engl J Med , vol.351 , Issue.27 , pp. 2805-2816
    • Gragoudas, E.S.1    Adamis, A.P.2    Cunningham Jr., E.T.3
  • 55
    • 14344259534 scopus 로고    scopus 로고
    • VEGF Inhibition Study in Ocular Neovascularization-1 (VISION-1): Safety evaluation from the pivotal Macugen™ (pegaptanib sodium) clinical trials
    • E-abstract 2363
    • D'Amico D, Bird AC. VEGF Inhibition Study in Ocular Neovascularization-1 (VISION-1): safety evaluation from the pivotal Macugen™ (pegaptanib sodium) clinical trials [E-abstract 2363]. Invest Ophthalmol Vis Sci 2004; 45 Suppl.
    • (2004) Invest Ophthalmol Vis Sci , vol.45 , Issue.SUPPL.
    • D'Amico, D.1    Bird, A.C.2
  • 57
    • 0036129304 scopus 로고    scopus 로고
    • Prevention of experimental choroidal neovascularization with intravitreal anti-vascular endothelial growth factor antibody fragment
    • Krzystolik MG, Afshari MA, Adamis AP, et al. Prevention of experimental choroidal neovascularization with intravitreal anti-vascular endothelial growth factor antibody fragment. Arch Ophthalmol 2002; 120 (3): 338-46
    • (2002) Arch Ophthalmol , vol.120 , Issue.3 , pp. 338-346
    • Krzystolik, M.G.1    Afshari, M.A.2    Adamis, A.P.3
  • 58
    • 33645641520 scopus 로고    scopus 로고
    • Ranibizumab for treatment of neovascular age-related macular degeneration: A phase I/II multicenter, controlled, multidose study
    • Epub Feb 13
    • Heier JS, Antoszyk AN, Pavan PR, et al. Ranibizumab for treatment of neovascular age-related macular degeneration: a phase I/II multicenter, controlled, multidose study. Ophthalmology. Epub 2006 Feb 13
    • (2006) Ophthalmology
    • Heier, J.S.1    Antoszyk, A.N.2    Pavan, P.R.3
  • 59
    • 20444496677 scopus 로고    scopus 로고
    • Review of Lucentis™ (randibizumab, rhuFab V2) phase I/II trial results: 6-month treatment of exsudative AMD
    • E-abstract 1109
    • Heier JS. Review of Lucentis™ (randibizumab, rhuFab V2) phase I/II trial results: 6-month treatment of exsudative AMD [E-abstract 1109]. Invest Ophthalmol Vis Sci 2004; 45 Suppl.
    • (2004) Invest Ophthalmol Vis Sci , vol.45 , Issue.SUPPL.
    • Heier, J.S.1
  • 62
    • 20544455330 scopus 로고    scopus 로고
    • Bevacizumab (Avastin), a humanized anti-VEGF monoclonal antibody for cancer therapy
    • Jul 29
    • Ferrara N, Hillan KJ, Novotny W. Bevacizumab (Avastin), a humanized anti-VEGF monoclonal antibody for cancer therapy. Biochem Biophys Res Commun 2005 Jul 29; 333 (2): 328-35
    • (2005) Biochem Biophys Res Commun , vol.333 , Issue.2 , pp. 328-335
    • Ferrara, N.1    Hillan, K.J.2    Novotny, W.3
  • 63
    • 20144372969 scopus 로고    scopus 로고
    • Systemic bevacizumab (Avastin) therapy for neovascular age-related macular degeneration twelve-week results of an uncontrolled open-label clinical study
    • Michels S, Rosenfeld PJ, Puliafito CA, et al. Systemic bevacizumab (Avastin) therapy for neovascular age-related macular degeneration twelve-week results of an uncontrolled open-label clinical study. Ophthalmology 2005; 112 (6): 1035-47
    • (2005) Ophthalmology , vol.112 , Issue.6 , pp. 1035-1047
    • Michels, S.1    Rosenfeld, P.J.2    Puliafito, C.A.3
  • 64
    • 23044505200 scopus 로고    scopus 로고
    • Optical coherence tomography findings after an intravitreal injection of bevacizumab (Avastin) for neovascular age-related macular degeneration
    • Rosenfeld PJ, Moshfeghi AA, Puliafito CA. Optical coherence tomography findings after an intravitreal injection of bevacizumab (Avastin) for neovascular age-related macular degeneration. Ophthalmic Surg Lasers Imaging 2005; 36 (4): 331-5
    • (2005) Ophthalmic Surg Lasers Imaging , vol.36 , Issue.4 , pp. 331-335
    • Rosenfeld, P.J.1    Moshfeghi, A.A.2    Puliafito, C.A.3
  • 65
    • 23044440795 scopus 로고    scopus 로고
    • Optical coherence tomography findings after an intravitreal injection of bevacizumab (Avastin) for macular edema from central retinal vein occlusion
    • Jul-Aug
    • Rosenfeld PJ, Fung AE, Puliafito CA. Optical coherence tomography findings after an intravitreal injection of bevacizumab (Avastin) for macular edema from central retinal vein occlusion. Ophthalmic Surg Lasers Imaging 2005 Jul-Aug; 36 (4): 336-9
    • (2005) Ophthalmic Surg Lasers Imaging , vol.36 , Issue.4 , pp. 336-339
    • Rosenfeld, P.J.1    Fung, A.E.2    Puliafito, C.A.3
  • 66
    • 33646446084 scopus 로고    scopus 로고
    • Intravitreal bevacizumab (Avastin) treatment of macular edema in central retinal vein occlusion: A short-term study
    • Mar
    • Iturralde D, Spaide RF, Meyerle CB, et al. Intravitreal bevacizumab (Avastin) treatment of macular edema in central retinal vein occlusion: a short-term study. Retina 2006 Mar; 26 (3): 279-84
    • (2006) Retina , vol.26 , Issue.3 , pp. 279-284
    • Iturralde, D.1    Spaide, R.F.2    Meyerle, C.B.3
  • 67
    • 33646464279 scopus 로고    scopus 로고
    • Intravitreal bevacizumab (Avastin) treatment of proliferative diabetic retinopathy complicated by vitreous hemorrhage
    • Mar
    • Spaide RF, Fisher YL. Intravitreal bevacizumab (Avastin) treatment of proliferative diabetic retinopathy complicated by vitreous hemorrhage. Retina 2006 Mar; 26 (3): 275-8
    • (2006) Retina , vol.26 , Issue.3 , pp. 275-278
    • Spaide, R.F.1    Fisher, Y.L.2
  • 68
    • 33644502828 scopus 로고    scopus 로고
    • Intravitreal bevacizumab (Avastin) for neovascular age-related macular degeneration
    • Mar
    • Avery RL, Pieramici DJ, Rabena MD, et al. Intravitreal bevacizumab (Avastin) for neovascular age-related macular degeneration. Ophthalmology 2006 Mar; 113 (3): 363-72
    • (2006) Ophthalmology , vol.113 , Issue.3 , pp. 363-372
    • Avery, R.L.1    Pieramici, D.J.2    Rabena, M.D.3
  • 69
    • 7444261960 scopus 로고    scopus 로고
    • Use of soluble recombinant decoy receptor vascular endothelial growth factor trap (VEGF Trap) to inhibit vascular endothelial growth factor activity
    • Konner J, Dupont J. Use of soluble recombinant decoy receptor vascular endothelial growth factor trap (VEGF Trap) to inhibit vascular endothelial growth factor activity. Clin Colorectal Cancer 2004; 4 Suppl. 2: S81-5
    • (2004) Clin Colorectal Cancer , vol.4 , Issue.2 SUPPL.
    • Konner, J.1    Dupont, J.2
  • 70
    • 0037143764 scopus 로고    scopus 로고
    • VEGF-Trap: A VEGF blocker with potent antitumor effects
    • U S A
    • Holash J, Davis S, Papadopoulos N, et al. VEGF-Trap: a VEGF blocker with potent antitumor effects. Proc Natl Acad Sci U S A 2002; 99 (17): 11393-8
    • (2002) Proc Natl Acad Sci , vol.99 , Issue.17 , pp. 11393-11398
    • Holash, J.1    Davis, S.2    Papadopoulos, N.3
  • 71
    • 0037401890 scopus 로고    scopus 로고
    • VEGF-Trap (R1R2) suppresses choroidal neovascularization and VEGF-induced breakdown of the blood-retinal barrier
    • Saishin Y, Takahashi K, Lima e Silva R, et al. VEGF-Trap (R1R2) suppresses choroidal neovascularization and VEGF-induced breakdown of the blood-retinal barrier. J Cell Physiol 2003; 195 (2): 241-8
    • (2003) J Cell Physiol , vol.195 , Issue.2 , pp. 241-248
    • Saishin, Y.1    Takahashi, K.2    Lima E Silva, R.3
  • 72
    • 0347991936 scopus 로고    scopus 로고
    • Squalamine lactate reduces choroidal neovascularization in a laser-injury model in the rat
    • Ciulla TA, Criswell MH, Danis RP, et al. Squalamine lactate reduces choroidal neovascularization in a laser-injury model in the rat. Retina 2003; 23 (6): 808-14
    • (2003) Retina , vol.23 , Issue.6 , pp. 808-814
    • Ciulla, T.A.1    Criswell, M.H.2    Danis, R.P.3
  • 73
    • 0036901287 scopus 로고    scopus 로고
    • Effect of squalamine on iris neovascularization in monkeys
    • Genaidy M, Kazi AA, Peyman GA, et al. Effect of squalamine on iris neovascularization in monkeys. Retina 2002; 22 (6): 772-8
    • (2002) Retina , vol.22 , Issue.6 , pp. 772-778
    • Genaidy, M.1    Kazi, A.A.2    Peyman, G.A.3
  • 74
    • 0034098181 scopus 로고    scopus 로고
    • Squalamine improves retinal neovascularization
    • Higgins RD, Sanders RJ, Yan Y, et al. Squalamine improves retinal neovascularization. Invest Ophthalmol Vis Sci 2000; 41 (6): 1507-12
    • (2000) Invest Ophthalmol Vis Sci , vol.41 , Issue.6 , pp. 1507-1512
    • Higgins, R.D.1    Sanders, R.J.2    Yan, Y.3
  • 76
    • 0035956869 scopus 로고    scopus 로고
    • Prevention of ischemia-induced retinopathy by the natural ocular antiangiogenic agent pigment epithelium-derived factor
    • U S A
    • Stellmach V, Crawford SE, Zhou W, et al. Prevention of ischemia-induced retinopathy by the natural ocular antiangiogenic agent pigment epithelium-derived factor. Proc Natl Acad Sci U S A 2001; 98 (5): 2593-7
    • (2001) Proc Natl Acad Sci , vol.98 , Issue.5 , pp. 2593-2597
    • Stellmach, V.1    Crawford, S.E.2    Zhou, W.3
  • 77
    • 0036297886 scopus 로고    scopus 로고
    • Regression of ocular neovascularization in response to increased expression of pigment epithelium-derived factor
    • Mori K, Gehlbach P, Ando A, et al. Regression of ocular neovascularization in response to increased expression of pigment epithelium-derived factor. Invest Ophthalmol Vis Sci 2002; 43 (7): 2428-34
    • (2002) Invest Ophthalmol Vis Sci , vol.43 , Issue.7 , pp. 2428-2434
    • Mori, K.1    Gehlbach, P.2    Ando, A.3
  • 78
    • 0036271989 scopus 로고    scopus 로고
    • AAV-mediated gene transfer of pigment epithelium-derived factor inhibits choroidal neovascularization
    • Mori K, Gehlbach P, Yamamoto S, et al. AAV-mediated gene transfer of pigment epithelium-derived factor inhibits choroidal neovascularization. Invest Ophthalmol Vis Sci 2002; 43 (6): 1994-2000
    • (2002) Invest Ophthalmol Vis Sci , vol.43 , Issue.6 , pp. 1994-2000
    • Mori, K.1    Gehlbach, P.2    Yamamoto, S.3
  • 79
    • 33744923789 scopus 로고    scopus 로고
    • Deficiency of anti-angiogenic pigment epithelial-derived factor in the vitreous of patients with wet age-related macular degeneration
    • 2001 Sep 13-16; Chicago (IL). Boston (MA) The Retina Society
    • Holekamp NM. Deficiency of anti-angiogenic pigment epithelial-derived factor in the vitreous of patients with wet age-related macular degeneration. In: Proceedings of the 34th Annual Scientific Meeting of the Retina Society; 2001 Sep 13-16; Chicago (IL). Boston (MA) The Retina Society, 2001: 66
    • (2001) Proceedings of the 34th Annual Scientific Meeting of the Retina Society , pp. 66
    • Holekamp, N.M.1
  • 80
    • 0036235046 scopus 로고    scopus 로고
    • Expression of pigment epithelium-derived factor in experimental choroidal neovascularization
    • Renno RZ, Youssri AI, Michaud N, et al. Expression of pigment epithelium-derived factor in experimental choroidal neovascularization. Invest Ophthalmol Vis Sci 2002; 43 (5): 1574-80
    • (2002) Invest Ophthalmol Vis Sci , vol.43 , Issue.5 , pp. 1574-1580
    • Renno, R.Z.1    Youssri, A.I.2    Michaud, N.3
  • 81
    • 0035514256 scopus 로고    scopus 로고
    • Clinical protocol. An open-label, phase I, single administration, dose-escalation study of ADGVPEDF.11D (ADPEDF) in neovascular age-related macular degeneration (AMD)
    • Rasmussen H, Chu KW, Campochiaro P, et al. Clinical protocol. An open-label, phase I, single administration, dose-escalation study of ADGVPEDF.11D (ADPEDF) in neovascular age-related macular degeneration (AMD). Hum Gene Ther 2001; 12 (16): 2029-32
    • (2001) Hum Gene Ther , vol.12 , Issue.16 , pp. 2029-2032
    • Rasmussen, H.1    Chu, K.W.2    Campochiaro, P.3
  • 82
    • 0030454243 scopus 로고    scopus 로고
    • Effects of topical dorzolamide on retinal and retrobulbar hemodynamics
    • Harris A, Arend O, Arend S, et al. Effects of topical dorzolamide on retinal and retrobulbar hemodynamics. Acta Ophthalmol Scand 1996; 74 (6): 569-72
    • (1996) Acta Ophthalmol Scand , vol.74 , Issue.6 , pp. 569-572
    • Harris, A.1    Arend, O.2    Arend, S.3
  • 83
    • 0031719049 scopus 로고    scopus 로고
    • Matrix metalloproteinases and metalloproteinase inhibitors in choroidal neovascular membranes
    • Steen B, Sejersen S, Berglin L, et al. Matrix metalloproteinases and metalloproteinase inhibitors in choroidal neovascular membranes. Invest Ophthalmol Vis Sci 1998; 39 (11): 2194-200
    • (1998) Invest Ophthalmol Vis Sci , vol.39 , Issue.11 , pp. 2194-2200
    • Steen, B.1    Sejersen, S.2    Berglin, L.3
  • 84
    • 0032837028 scopus 로고    scopus 로고
    • Broad antitumor and antiangiogenic activities of AG3340, a potent and selective MMP inhibitor undergoing advanced oncology clinical trials
    • Shalinsky DR, Brekken J, Zou H, et al. Broad antitumor and antiangiogenic activities of AG3340, a potent and selective MMP inhibitor undergoing advanced oncology clinical trials. Ann N Y Acad Sci 1999; 878: 236-70
    • (1999) Ann N Y Acad Sci , vol.878 , pp. 236-270
    • Shalinsky, D.R.1    Brekken, J.2    Zou, H.3
  • 85
    • 0038011879 scopus 로고    scopus 로고
    • Pharmacological therapy for age-related macular degeneration: Current developments and perspectives
    • Feb
    • Holz FG, Miller DW. Pharmacological therapy for age-related macular degeneration: current developments and perspectives [in German]. Ophthalmologe 2003 Feb; 100 (2): 97-103
    • (2003) Ophthalmologe , vol.100 , Issue.2 , pp. 97-103
    • Holz, F.G.1    Miller, D.W.2
  • 86
    • 33744932535 scopus 로고    scopus 로고
    • Aeterna Zentaris [online]
    • Aeterna Zentaris. Neovastat® product sheet. Aeterna Zentaris [online]. Available from URL: http://www.aeternazentaris.com [Accessed 2006 Apr 28]
    • Neovastat® Product Sheet
  • 87
    • 0022366074 scopus 로고
    • A new class of steroids inhibits angiogenesis in the presence of heparin or a heparin fragment
    • Crum R, Szabo S, Folkman J. A new class of steroids inhibits angiogenesis in the presence of heparin or a heparin fragment. Science 1985; 230 (4732): 1375-8
    • (1985) Science , vol.230 , Issue.4732 , pp. 1375-1378
    • Crum, R.1    Szabo, S.2    Folkman, J.3
  • 88
    • 0030955337 scopus 로고    scopus 로고
    • Topical formulations of novel angiostatic steroids inhibit rabbit corneal neovascularization
    • BenEzra D, Griffin BW, Maftzir G, et al. Topical formulations of novel angiostatic steroids inhibit rabbit corneal neovascularization. Invest Ophthalmol Vis Sci 1997; 38 (10): 1954-62
    • (1997) Invest Ophthalmol Vis Sci , vol.38 , Issue.10 , pp. 1954-1962
    • BenEzra, D.1    Griffin, B.W.2    Maftzir, G.3
  • 89
    • 0035161760 scopus 로고    scopus 로고
    • The effect of an angiostatic steroid on neovascularization in a rat model of retinopathy of prematurity
    • Penn JS, Rajaratnam VS, Collier RJ, et al. The effect of an angiostatic steroid on neovascularization in a rat model of retinopathy of prematurity. Invest Ophthalmol Vis Sci 2001; 42 (1): 283-90
    • (2001) Invest Ophthalmol Vis Sci , vol.42 , Issue.1 , pp. 283-290
    • Penn, J.S.1    Rajaratnam, V.S.2    Collier, R.J.3
  • 90
    • 6544281475 scopus 로고    scopus 로고
    • Inhibition of intraocular tumor growth by topical application of the angiostatic steroid anecortave acetate
    • Clark AF, Mellon J, Li XY, et al. Inhibition of intraocular tumor growth by topical application of the angiostatic steroid anecortave acetate. Invest Ophthalmol Vis Sci 1999; 40 (9): 2158-62
    • (1999) Invest Ophthalmol Vis Sci , vol.40 , Issue.9 , pp. 2158-2162
    • Clark, A.F.1    Mellon, J.2    Li, X.Y.3
  • 91
    • 0032882397 scopus 로고    scopus 로고
    • Angiostatic activity of steroids in the chick embryo CAM and rabbit cornea models of neovascularization
    • McNatt LG, Weimer L, Yanni J, et al. Angiostatic activity of steroids in the chick embryo CAM and rabbit cornea models of neovascularization. J Ocul Pharmacol Ther 1999; 15 (5): 413-23
    • (1999) J Ocul Pharmacol Ther , vol.15 , Issue.5 , pp. 413-423
    • McNatt, L.G.1    Weimer, L.2    Yanni, J.3
  • 92
    • 0026650294 scopus 로고
    • Angiostatic activity and metabolism of cortisol in the chorioallantoic membrane (CAM) of the chick embryo
    • McNatt LG, Lane D, Clark AF. Angiostatic activity and metabolism of cortisol in the chorioallantoic membrane (CAM) of the chick embryo. J Steroid Biochem Mol Biol 1992; 42 (7): 687-93
    • (1992) J Steroid Biochem Mol Biol , vol.42 , Issue.7 , pp. 687-693
    • McNatt, L.G.1    Lane, D.2    Clark, A.F.3
  • 93
    • 0024263955 scopus 로고
    • Angiogenic activity of rat mammary carcinomas induced by 7,12-dimethylbenz[a]anthracene and its inhibition by medroxyprogesterone acetate: Possible involvement of antiangiogenic action of medroxyprogesterone acetate in its tumor growth inhibition
    • Oikawa T, Hiragun A, Yoshida Y, et al. Angiogenic activity of rat mammary carcinomas induced by 7,12-dimethylbenz[a]anthracene and its inhibition by medroxyprogesterone acetate: possible involvement of antiangiogenic action of medroxyprogesterone acetate in its tumor growth inhibition. Cancer Lett 1988; 43 (1-2): 85-92
    • (1988) Cancer Lett , vol.43 , Issue.1-2 , pp. 85-92
    • Oikawa, T.1    Hiragun, A.2    Yoshida, Y.3
  • 94
    • 0027758857 scopus 로고
    • The effect of angiostatic steroids and beta-cyclodextrin tetradecasulfate on corneal neovascularization in the rat
    • Proia AD, Hirakata A, McInnes JS, et al. The effect of angiostatic steroids and beta-cyclodextrin tetradecasulfate on corneal neovascularization in the rat. Exp Eye Res 1993; 57 (6): 693-8
    • (1993) Exp Eye Res , vol.57 , Issue.6 , pp. 693-698
    • Proia, A.D.1    Hirakata, A.2    McInnes, J.S.3
  • 95
    • 0037299842 scopus 로고    scopus 로고
    • Anecortave acetate as monotherapy for the treatment of subfoveal lesions in patients with exudative age-related macular degeneration (AMD): Interim (month 6) analysis of clinical safety and efficacy
    • Feb
    • D'Amico DJ, Goldberg MF, Hudson H, Anecortave Acetate Clinical Study Group, et al. Anecortave acetate as monotherapy for the treatment of subfoveal lesions in patients with exudative age-related macular degeneration (AMD): interim (month 6) analysis of clinical safety and efficacy. Retina 2003 Feb; 23 (1): 14-23
    • (2003) Retina , vol.23 , Issue.1 , pp. 14-23
    • D'Amico, D.J.1    Goldberg, M.F.2    Hudson, H.3
  • 96
    • 0344442766 scopus 로고    scopus 로고
    • Anecortave acetate as monotherapy for treatment of subfoveal neovascularization in age-related macular degeneration: Twelve-month clinical outcomes
    • Dec
    • D'Amico DJ, Goldberg MF, Hudson H, Anecortave Acetate Clinical Study Group, et al. Anecortave acetate as monotherapy for treatment of subfoveal neovascularization in age-related macular degeneration: twelve-month clinical outcomes. Ophthalmology 2003 Dec; 110 (12): 2372-83
    • (2003) Ophthalmology , vol.110 , Issue.12 , pp. 2372-2383
    • D'Amico, D.J.1    Goldberg, M.F.2    Hudson, H.3
  • 97
    • 23844489153 scopus 로고    scopus 로고
    • Anecortave acetate for the treatment of subfoveal choroidal neovascularization secondary to age-related macular degeneration
    • Schmidt-Erfurth U, Michels S, Michels R, et al. Anecortave acetate for the treatment of subfoveal choroidal neovascularization secondary to age-related macular degeneration. Eur J Ophthalmol 2005; 15 (4): 482-5
    • (2005) Eur J Ophthalmol , vol.15 , Issue.4 , pp. 482-485
    • Schmidt-Erfurth, U.1    Michels, S.2    Michels, R.3
  • 98
    • 0035098289 scopus 로고    scopus 로고
    • Intravitreal triamcinolone acetonide inhibits choroidal neovascularization in a laser-treated rat model
    • Ciulla TA, Criswell MH, Danis RP, et al. Intravitreal triamcinolone acetonide inhibits choroidal neovascularization in a laser-treated rat model. Arch Ophthalmol 2001; 119 (3): 399-404
    • (2001) Arch Ophthalmol , vol.119 , Issue.3 , pp. 399-404
    • Ciulla, T.A.1    Criswell, M.H.2    Danis, R.P.3
  • 99
    • 33744921200 scopus 로고    scopus 로고
    • Angiostatic effect of crystalline triamcinolone acetonide on ocular neovascularization in vivo
    • E-abstract 2497.
    • Spandau U, Sauder G, Jonas JB, et al. Angiostatic effect of crystalline triamcinolone acetonide on ocular neovascularization in vivo [E-abstract 2497]. Invest Ophthalmol Vis Sci 2002; 43 Suppl.
    • (2002) Invest Ophthalmol Vis Sci , vol.43 , Issue.SUPPL.
    • Spandau, U.1    Sauder, G.2    Jonas, J.B.3
  • 100
    • 0037653669 scopus 로고    scopus 로고
    • A randomized clinical trial of a single dose of intravitreal triamcinolone acetonide for neovascular age-related macular degeneration: One-year results
    • Gillies M, Simpson J, Luo W, et al. A randomized clinical trial of a single dose of intravitreal triamcinolone acetonide for neovascular age-related macular degeneration: one-year results. Arch Ophthalmol 2003; 121 (5): 667-73
    • (2003) Arch Ophthalmol , vol.121 , Issue.5 , pp. 667-673
    • Gillies, M.1    Simpson, J.2    Luo, W.3
  • 101
    • 33744930954 scopus 로고    scopus 로고
    • Intravitreal triamcinolone injection for the treatment of occult choroidal neovascularization associated with age-related macular degeneration
    • E-abstract 2500
    • Roth D, Spirn M, Yarian DL, et al. Intravitreal triamcinolone injection for the treatment of occult choroidal neovascularization associated with age-related macular degeneration [E-abstract 2500]. Invest Ophthalmol Vis Sci 2002; 43 Suppl.
    • (2002) Invest Ophthalmol Vis Sci , vol.43 , Issue.SUPPL.
    • Roth, D.1    Spirn, M.2    Yarian, D.L.3
  • 102
    • 33744936127 scopus 로고    scopus 로고
    • Pilot study of intravitreal injektion of triamcinolone acetonide in exsudative age-related macular degeneration
    • E-abstract 1220
    • Moon S, Mieler WF, Holz ER. Pilot study of intravitreal injektion of triamcinolone acetonide in exsudative age-related macular degeneration [E-abstract 1220]. Invest Ophthalmol Vis Sci 2002; 43 Suppl.
    • (2002) Invest Ophthalmol Vis Sci , vol.43 , Issue.SUPPL.
    • Moon, S.1    Mieler, W.F.2    Holz, E.R.3
  • 103
    • 0037383719 scopus 로고    scopus 로고
    • Intravitreal triamcinolone acetonide for exsudative age-related macular degeneration
    • Jonas J, Kreissig I, Hugger P, et al. Intravitreal triamcinolone acetonide for exsudative age-related macular degeneration. Br J Ophthalmol 2003; 87: 462-8
    • (2003) Br J Ophthalmol , vol.87 , pp. 462-468
    • Jonas, J.1    Kreissig, I.2    Hugger, P.3
  • 104
    • 17744377410 scopus 로고    scopus 로고
    • Influence of plasminogen activator inhibitor type 1 on choroidal neovascularization
    • Lambert V, Munaut C, Noel A, et al. Influence of plasminogen activator inhibitor type 1 on choroidal neovascularization. FASEB J 2001; 15 (6): 1021-7
    • (2001) FASEB J , vol.15 , Issue.6 , pp. 1021-1027
    • Lambert, V.1    Munaut, C.2    Noel, A.3
  • 105
    • 29644440836 scopus 로고    scopus 로고
    • Anecortave acetate (15 milligrams) versus photodynamic therapy for treatment of subfoveal neovascularization in age-related macular degeneration
    • Slakter JS, Bochow TW, D'Amico DJ, Anecortave Acetate Clinical Study Group, et al. Anecortave acetate (15 milligrams) versus photodynamic therapy for treatment of subfoveal neovascularization in age-related macular degeneration. Ophthalmology 2006 Jan; 113 (1): 3-13
    • (2006) Ophthalmology , vol.113 , Issue.1 , pp. 3-13
    • Slakter, J.S.1    Bochow, T.W.2    D'Amico, D.J.3
  • 106
    • 0042029477 scopus 로고    scopus 로고
    • Combined photodynamic therapy with verteporfin and intravitreal triamcinolone acetonide for choroidal neovascularization
    • Spaide RF, Sorenson J, Maranan L. Combined photodynamic therapy with verteporfin and intravitreal triamcinolone acetonide for choroidal neovascularization. Ophthalmology 2003; 110 (8): 1517-25
    • (2003) Ophthalmology , vol.110 , Issue.8 , pp. 1517-1525
    • Spaide, R.F.1    Sorenson, J.2    Maranan, L.3
  • 107
    • 0141430051 scopus 로고    scopus 로고
    • Influence of photodynamic therapy on expression of vascular endothelial growth factor (VEGF), VEGF receptor 3, and pigment epithelium-derived factor
    • Schmidt-Erfurth U, Schlotzer-Schrehard U, Cursiefen C, et al. Influence of photodynamic therapy on expression of vascular endothelial growth factor (VEGF), VEGF receptor 3, and pigment epithelium-derived factor. Invest Ophthalmol Vis Sci 2003; 44 (10): 4473-80
    • (2003) Invest Ophthalmol Vis Sci , vol.44 , Issue.10 , pp. 4473-4480
    • Schmidt-Erfurth, U.1    Schlotzer-Schrehard, U.2    Cursiefen, C.3
  • 108
    • 1542407176 scopus 로고    scopus 로고
    • Intravitreal triamcinolone with photodynamic therapy for subfoveal choroidal neovascularisation in age related macular degeneration
    • Rechtman E, Danis RP, Pratt LM, et al. Intravitreal triamcinolone with photodynamic therapy for subfoveal choroidal neovascularisation in age related macular degeneration. Br J Ophthalmol 2004; 88 (3): 344-7
    • (2004) Br J Ophthalmol , vol.88 , Issue.3 , pp. 344-347
    • Rechtman, E.1    Danis, R.P.2    Pratt, L.M.3
  • 109
    • 13444273215 scopus 로고    scopus 로고
    • Photodynamic therapy with verteporfin combined with intravitreal injection of triamcinolone acetonide for choroidal neovascularization
    • Spaide RF, Sorenson J, Maranan L. Photodynamic therapy with verteporfin combined with intravitreal injection of triamcinolone acetonide for choroidal neovascularization. Ophthalmology 2005; 112 (2): 301-4
    • (2005) Ophthalmology , vol.112 , Issue.2 , pp. 301-304
    • Spaide, R.F.1    Sorenson, J.2    Maranan, L.3
  • 110
    • 0035214416 scopus 로고    scopus 로고
    • Metronomic scheduling: The future of chemotherapy?
    • Gasparini G. Metronomic scheduling: the future of chemotherapy? Lancet Oncol 2001; 2: 733-40
    • (2001) Lancet Oncol , vol.2 , pp. 733-740
    • Gasparini, G.1
  • 111
    • 33744911215 scopus 로고    scopus 로고
    • Intravitreale methotrexat-injektionen bei choroidalen neovaskularisationen im rahmen der altersabḧangigen makuladegeneration (AMD) [poster 158] Sep 23-26; Berlin
    • Karl S, Bindewald A, Roth F, et al. Intravitreale methotrexat-injektionen bei choroidalen neovaskularisationen im rahmen der altersabḧangigen makuladegeneration (AMD) [poster 158]. Proceedings of the German Society of Ophthalmology (DOG) 2004 Annual Meeting; 2004 Sep 23-26; Berlin
    • (2004) Proceedings of the German Society of Ophthalmology (DOG) 2004 Annual Meeting
    • Karl, S.1    Bindewald, A.2    Roth, F.3
  • 112
    • 0019306152 scopus 로고
    • Inhibition of cell motility by interferon
    • Brouty-Boye D, Zetter BR. Inhibition of cell motility by interferon. Science 1980; 208 (4443): 516-8
    • (1980) Science , vol.208 , Issue.4443 , pp. 516-518
    • Brouty-Boye, D.1    Zetter, B.R.2
  • 113
    • 0027398874 scopus 로고
    • Interferon alpha-2a treatment of patients with subfoveal neovascular macular degeneration: A pilot investigation
    • Copenh
    • Engler CB, Sander B, Koefoed P, et al. Interferon alpha-2a treatment of patients with subfoveal neovascular macular degeneration: a pilot investigation. Acta Ophthalmol (Copenh) 1993; 71 (1): 27-31
    • (1993) Acta Ophthalmol , vol.71 , Issue.1 , pp. 27-31
    • Engler, C.B.1    Sander, B.2    Koefoed, P.3
  • 114
    • 0026525407 scopus 로고
    • Interferon alfa-2a therapy for life-threatening hemangiomas of infancy
    • Ezekowitz RA, Mulliken JB, Folkman J. Interferon alfa-2a therapy for life-threatening hemangiomas of infancy. N Engl J Med 1992; 326 (22): 1456-63
    • (1992) N Engl J Med , vol.326 , Issue.22 , pp. 1456-1463
    • Ezekowitz, R.A.1    Mulliken, J.B.2    Folkman, J.3
  • 115
    • 0025799511 scopus 로고
    • Interferon alpha 2a for treatment of age-related macular degeneration
    • Fung WE. Interferon alpha 2a for treatment of age-related macular degeneration. Am J Ophthalmol 1991; 112 (3): 349-50
    • (1991) Am J Ophthalmol , vol.112 , Issue.3 , pp. 349-350
    • Fung, W.E.1
  • 116
    • 8544270082 scopus 로고    scopus 로고
    • Interferon alfa-2a is ineffective for patients with choroidal neovascularization secondary to age-related macular degeneration: Results of a prospective randomized placebocontrolled clinical trial
    • Pharmacological Therapy for Macular Degeneration Study Group
    • Pharmacological Therapy for Macular Degeneration Study Group. Interferon alfa-2a is ineffective for patients with choroidal neovascularization secondary to age-related macular degeneration: results of a prospective randomized placebocontrolled clinical trial. Pharmacological Therapy for Macular Degeneration Study Group. Arch Ophthalmol 1997; 115 (7): 865-72
    • (1997) Arch Ophthalmol , vol.115 , Issue.7 , pp. 865-872
  • 117
    • 0000727887 scopus 로고    scopus 로고
    • AMDATS Research Group: Results of the age-related macular degeneration and thalidomide study (AMDATS)
    • Maguire M, Fine SL, Maguire AM, et al. AMDATS Research Group: results of the age-related macular degeneration and thalidomide study (AMDATS) [abstract]. Invest Ophthalmol Vis Sci 2001; 42: 233
    • (2001) Invest Ophthalmol Vis Sci , vol.42 , pp. 233
    • Maguire, M.1    Fine, S.L.2    Maguire, A.M.3
  • 118
    • 0038748037 scopus 로고    scopus 로고
    • Small interfering RNA (siRNA) targeting VEGF effectively inhibits ocular neovascularization in a mouse model
    • Reich S, Fosnot J, Akiko K, et al. Small interfering RNA (siRNA) targeting VEGF effectively inhibits ocular neovascularization in a mouse model. Mol Vis 2003; 9: 210-6
    • (2003) Mol Vis , vol.9 , pp. 210-216
    • Reich, S.1    Fosnot, J.2    Akiko, K.3
  • 119
    • 1242297011 scopus 로고    scopus 로고
    • Intravitreal injection of vascular endothelial growth factor small interfering RNA inhibits growth and leakage in a nonhuman primate, laser-induced model of choroidal Neovascularization
    • Tolentino MJ, Brucker AJ, Joshua F, et al. Intravitreal injection of vascular endothelial growth factor small interfering RNA inhibits growth and leakage in a nonhuman primate, laser-induced model of choroidal Neovascularization. Retina 2004; 24: 132-8
    • (2004) Retina , vol.24 , pp. 132-138
    • Tolentino, M.J.1    Brucker, A.J.2    Joshua, F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.