Influence of plasminogen activator inhibitor type 1 on choroidal neovascularization

FASEB Journal

Volumn 15, Issue 6, 2001, Pages 1021-1027

  Lambert, Vincent ^a   Munaut, Carine ^a   Noël, Agnès ^a   Frankenne, Francis ^a   Bajou, Khalid ^a   Gerard, Robert ^b   Carmeliet, Peter ^b   Defresne, Marie Paule ^a   Foidart, Jean Michel ^a   Rakic, Jean Marie ^c  

^a UNIVERSITY OF LIÈGE   (Belgium)

^b DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^c UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

Angiogenesis; Macular degeneration; Proteases; Retinal disease; Viral vector

Indexed keywords

COMPLEMENTARY DNA; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEINASE; VIRUS VECTOR;

ADENOVIRUS; ANGIOGENESIS; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FLUORESCENCE ANGIOGRAPHY; GENE TRANSFER; MOUSE; NONHUMAN; PRIORITY JOURNAL; RETINA DISEASE; RETINA MACULA DEGENERATION; SUBRETINAL NEOVASCULARIZATION;

ADENOVIRIDAE; ANIMALS; CHOROIDAL NEOVASCULARIZATION; DNA, COMPLEMENTARY; FEMALE; GENETIC VECTORS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PLASMINOGEN ACTIVATOR INHIBITOR 1; TRANSFECTION;

ADENOVIRIDAE; ANIMALIA;

EID: 17744377410     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.00-0393com     Document Type: Article

References (33)

1. Requirement of vascular integrin alpha v beta 3 for angiogenesis
2. Involvement of integrins alpha v beta 3 and alpha v beta 5 in ocular neovascular diseases
3. Antagonists of integrin alpha v beta 3 inhibit retinal neovascularization in a murine model
4. Subcutaneous injection of a cyclic peptide antagonist of vitronectin receptor-type integrins inhibits retinal neovascularization
5. Subfoveal fibrovascular membranes in age-related macular degeneration express vascular endothelial growth factor
6. Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders
7. Vascular endothelial growth factor/vascular permeability factor expression in a mouse model of retinal neovascularization
8. Transgenic mice with increased expression of vascular endothelial growth factor in the retina: A new model of intraretinal and subretinal neovascularization
9. Polarized vascular endothelial growth factor secretion by human retinal pigment epithelium and localization of vascular endothelial growth factor receptors on the inner choriocapillaris. Evidence for a trophic paracrine relation
10. Fas ligand (CD95 ligand) controls angiogenesis beneath the retina
11. Mutations in the tissue inhibitor of metalloproteinases-3 (TIMP3) in patients with Sorsby's fundus dystrophy
12. Matrix metalloproteinases and metalloproteinase inhibitors in choroidal neovascular membranes
13. The urokinase-type plasminogen activator system in cancer metastasis: A review
14. Proteolysis, cell adhesion, chemotaxis, and invasiveness are regulated by the u-PA-u-PAR-PAI-1 system
15. Absence of host plasminogen activator inhibitor 1 prevents cancer invasion and vascularization
16. Prognostic impact of urokinase, urokinase receptor, and type 1 plasminogen activator inhibitor in squamous and large cell lung cancer tissue
17. Plasminogen activator inhibitor-1 overexpression in nonproliferative diabetic retinopathy
18. Plasminogen activator inhibitor 1 in central serous chorioretinopathy
19. Targeted disruption of the FGF2 gene does not prevent choroidal neovascularization in a murine model
20. Plasminogen activator inhibitor-1 gene-deficient mice. 1. Generation by homologous recombination and characterization
21. Sequences 5′ of the homeobox of the Hox-1.4 gene direct tissue-specific expression of lacZ during mouse development
22. Inhibitory role of plasminogen activator inhibitor-1 in arterial wound healing and neointima formation: A gene targeting and gene transfer study in mice
23. Blood vessel formation: What is its molecular basis?
24. Tissue plasminogen activator activity in human aqueous humor
25. Plasminogen activator and PAI. Detection in aqueous humor of the human eye
26. TIMP-3 in Bruch's membrane: Changes during aging and in age-related macular degeneration
27. Increase in interphotoreceptor matrix gelatinase A (MMP-2) associated with age-related macular degeneration
28. ProMMP-9 (92 kDa gelatinase) in vitreous fluid of patients with proliferative diabetic retinopathy
29. Vitreous concentrations of TPA and plasminogen activator inhibitor are associated with VEGF in proliferative diabetic vitreoretinopathy
30. Evidence that AL-3789 inhibits retinal neovascularization in an animal model of ROP by inducing retinal PAI-1
31. Increased proteolytic activity is responsible for the aberrant morphogenetic behavior of endothelial cells expressing the middle T oncogene
32. Regulation of cancer invasion and vascularization by plasminogen activator inhibitor-1
33. The mechanism of cancer-mediated conversion of plasminogen to the angiogenesis inhibitor angiostatin