Erythroblast transformation by the friend spleen focus-forming virus is associated with a block in erythropoietin-induced STAT1 phosphorylation and DNA binding and correlates with high expression of the hematopoietic phosphatase SHP-1

Journal of Virology

Volumn 80, Issue 12, 2006, Pages 5678-5685

  Nishigaki, Kazuo ^a,b   Hanson, Charlotte ^a   Ohashi, Takashi ^a,c   Spadaccini, Angelo ^a,d   Ruscetti, Sandra ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^c HOKKAIDO UNIVERSITY   (Japan)

^d CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; ERYTHROPOIETIN; ERYTHROPOIETIN RECEPTOR; JANUS KINASE 2; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE PHOSPHATASE SHP 1; STAT1 PROTEIN; STAT3 PROTEIN; TRANSCRIPTION FACTOR PU 1; VIRUS ENVELOPE PROTEIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; ERYTHROBLAST; ERYTHROID CELL; ERYTHROLEUKEMIA; FRIEND LEUKEMIA VIRUS; FRIEND SPLEEN FOCUS FORMING VIRUS; HYPERPLASIA; MOUSE; NONHUMAN; PHENOTYPE; POLYCYTHEMIA; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; RETROVIRUS; SIGNAL TRANSDUCTION; VIRUS CELL TRANSFORMATION;

ANIMALS; CELL DIFFERENTIATION; CELL TRANSFORMATION, VIRAL; DNA; ERYTHROBLASTS; ERYTHROPOIETIN; GENE EXPRESSION REGULATION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; PHOSPHORYLATION; PROTEIN-TYROSINE-PHOSPHATASE; PROTO-ONCOGENE PROTEINS; SHP1 PROTEIN TYROSINE PHOSPHATASE; SPLEEN FOCUS-FORMING VIRUSES; STAT1 TRANSCRIPTION FACTOR; TRANS-ACTIVATORS;

FRIEND MURINE LEUKEMIA VIRUS; FRIEND SPLEEN FOCUS-FORMING VIRUS; MURINAE; SPLEEN FOCUS-FORMING VIRUS;

EID: 33744925408     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.02651-05     Document Type: Article

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