Germline mutations of the hMLH1 and hMSH2 mismatch repair genes in Belgian hereditary nonpolyposis colon cancer (HNPCC) patients

Familial Cancer

Volumn 5, Issue 2, 2006, Pages 179-189

  Spaepen, M ^a,b   Vankeirsbilck, B ^a   Van Opstal, S ^a   Tejpar, S ^a   Van Cutsem, E ^a   Geboes, K ^a   Legius, E ^a   Matthijs, G ^a  

^a UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^b UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Hereditary nonpolyposis colon cancer (HNPCC); hMLH1; hMSH2; Microsatellite instability (MSI); Mismatch repair (MMR)

Indexed keywords

PROTEIN MLH1; PROTEIN MSH2;

ARTICLE; CLINICAL PRACTICE; CLUSTER ANALYSIS; COLORECTAL CANCER; CONTROLLED STUDY; DENATURING GRADIENT GEL ELECTROPHORESIS; FAMILIAL CANCER; FRAMESHIFT MUTATION; GENE DELETION; GENE DUPLICATION; GENE IDENTIFICATION; GENE MUTATION; GENE SEQUENCE; GENETIC SCREENING; GENETICS; GENOMICS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MICROSATELLITE INSTABILITY; MISMATCH REPAIR; MISSENSE MUTATION; MULTIPLEX POLYMERASE CHAIN REACTION; NONSENSE MUTATION; PATHOGENICITY; POINT MUTATION; PRIORITY JOURNAL; RNA SPLICING; SCREENING;

BASE PAIR MISMATCH; CARRIER PROTEINS; CODON, NONSENSE; COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS; DNA REPAIR; FRAMESHIFT MUTATION; GENE DELETION; GERM-LINE MUTATION; HUMANS; MICROSATELLITE REPEATS; MUTATION, MISSENSE; MUTS HOMOLOG 2 PROTEIN; NUCLEAR PROTEINS;

EID: 33744723159     PISSN: 13899600     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10689-005-5958-6     Document Type: Article

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