Genomic deletions of MSH2 and MLH1 in colorectal cancer families detected by a novel mutation detection approach

British Journal of Cancer

Volumn 87, Issue 8, 2002, Pages 892-897

  Gille, J J P ^a   Hogervorst, F B L ^b   Pals, G ^a   Wijnen, J Th ^c   Van Schooten, R J ^a   Dommering, C J ^a   Meijer, G A ^a   Craanen, M E ^a   Nederlof, P M ^b   De Jong, D ^b   McElgunn, C J ^d   Schouten, J P ^d   Menko, F H ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b NETHERLANDS CANCER INSTITUTE   (Netherlands)

^c LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^d MRC HOLLAND   (Netherlands)

Author keywords

Genomic deletions; HNPCC; Mismatch repair; Muir Torre syndrome

Indexed keywords

PROTEIN MLH1; PROTEIN MSH2;

ADULT; ARTICLE; AUTOSOMAL DOMINANT DISORDER; CANCER FAMILY; CLINICAL FEATURE; COLORECTAL CANCER; FEMALE; GENE DELETION; GENOME; HUMAN; MAJOR CLINICAL STUDY; MALE; MICROSATELLITE INSTABILITY; MISMATCH REPAIR; MUIR TORRE SYNDROME; MULTIPLEX LIGATION DEPENDENT PROBE AMPLIFICATION; MUTATIONAL ANALYSIS; PATHOGENICITY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; TECHNIQUE;

BASE PAIR MISMATCH; CARRIER PROTEINS; COHORT STUDIES; COLORECTAL NEOPLASMS; COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS; DNA REPAIR; DNA-BINDING PROTEINS; FAMILY; FEMALE; GENE DELETION; GERM-LINE MUTATION; HUMANS; MALE; MUTS HOMOLOG 2 PROTEIN; NEOPLASM PROTEINS; NUCLEAR PROTEINS; PEDIGREE; POLYMERASE CHAIN REACTION; PROTO-ONCOGENE PROTEINS;

EID: 18644386133     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjc.6600565     Document Type: Article

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