Isolation and Analyses of MutY Homologs (MYH)

Methods in Enzymology

Volumn 408, Issue , 2006, Pages 64-78

  Lu Chang, A Lien ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE; BACTERIAL ENZYME; CYCLINE; DNA (APURINIC OR APYRIMIDINIC SITE) LYASE; DNA GLYCOSYLTRANSFERASE; RECOMBINANT PROTEIN;

ADENOMA; ANISOTROPY; BACTERIAL CELL; BACTERIUM CULTURE; BINDING AFFINITY; CANCER GROWTH; COLON CANCER; DNA BINDING; DNA PROTEIN COMPLEX; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME ASSAY; ENZYME ISOLATION; ENZYME PURIFICATION; ESCHERICHIA COLI; EUKARYOTE; EXCISION REPAIR; FAR WESTERN BLOTTING; FLUORESCENCE; FLUORESCENCE ANALYSIS; GEL MOBILITY SHIFT ASSAY; GENE MUTATION; GENETIC ASSOCIATION; HUMAN; IMMUNOPRECIPITATION; MAMMAL; MISMATCH REPAIR; MUTATION RATE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN INTERACTION; REVIEW; SCHIZOSACCHAROMYCES POMBE;

ANIMALS; DNA DAMAGE; DNA GLYCOSYLASES; DNA REPAIR; FUNGAL PROTEINS; HUMANS; RECOMBINANT PROTEINS;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; EUKARYOTA; SCHIZOSACCHAROMYCES POMBE;

EID: 33744483437     PISSN: 00766879     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0076-6879(06)08005-0     Document Type: Review

References (37)

1. Bai H., Jones S., Guan X., Wilson T.M., Sampson J.R., Cheadle J.P., and Lu A.L. Functional characterization of two human MutY homolog (hMYH) missense mutations (R227W and V232F) that lie within the putative hMSH6 binding domain and are associated with hMYH polyposis. Nucleic Acids Res. 33 (2005) 597-604
2. Blaisdell J.O., Hatahet Z., and Wallace S.S. A novel role for Escherichia coli endonuclease VIII in prevention of spontaneous G → T transversions. J. Bacteriol. 181 (1999) 6396-6402
3. Bradford M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72 (1976) 248-254
4. Chang D.Y., and Lu A.-L. Functional interaction of MutY homolog (MYH) with proliferating cell nuclear antigen (PCNA) in fission yeast, Schizosaccharomyces pombe. J. Biol. Chem. 277 (2002) 11853-11858
5. Chang D.Y., and Lu A.-L. Interaction of checkpoint proteins Hus1/Rad1/Rad9 with DNA base excision repair enzyme MutY homolog in fission yeast, Schizosaccharomyces pombe. J. Biol. Chem. 280 (2005) 408-417
6. Cheadle J.P., and Sampson J.R. Exposing the MYH about base excision repair and human inherited disease. Hum. Mol. Genet. 12 (2003) R159-R165 Spec. No. 2
7. Chmiel N.H., Golinelli M.P., Francis A.W., and David S.S. Efficient recognition of substrates and substrate analogs by the adenine glycosylase MutY requires the C-terminal domain. Nucleic Acids Res. 29 (2001) 553-564
8. Cupples C.G., and Miller J.H. A set of lacZ mutations in Escherichia coli that allow rapid detection of each of the six base substitutions. Proc. Natl. Acad. Sci. USA 86 (1989) 5345-5349
9. Fromme J.C., Banerjee A., Huang S.J., and Verdine G.L. Structural basis for removal of adenine mispaired with 8-oxoguanine by MutY adenine DNA glycosylase. Nature 427 (2004) 652-656
10. Gogos A., Cillo J., Clarke N.D., and Lu A.-L. Specific recognition of A/G and A/8-oxoG mismatches by Escherichia coli MutY: Removal of the C-terminal domain preferentially affects A/8-oxoG recognition. Biochemistry 35 (1996) 16665-16671
11. Gu Y., and Lu A.-L. Differential DNA recognition and glycosylase activity of the native human MutY homolog (hMYH) and recombinant hMYH expressed in bacteria. Nucleic Acids Res. 29 (2001) 2666-2674
12. Gu Y., Parker A., Wilson T.M., Bai H., Chang D.Y., and Lu A.-L. Human MutY homolog (hMYH), a DNA glycosylase involved in base excision repair, physically and functionally interacts with mismatch repair proteins hMSH2/hMSH6. J. Biol. Chem. 277 (2002) 11135-11142
13. Guan Y., Manuel R.C., Arvai A.S., Parikh S.S., Mol C.D., Miller J.H., Lloyd S., and Tainer J.A. MutY catalytic core, mutant and bound adenine structures define specificity for DNA repair enzyme superfamily. Nature Struct. Biol. 5 (1998) 1058-1064
14. Hazra T.K., Hill J.W., Izumi T., and Mitra S. Multiple DNA glycosylases for repair of 8-oxoguanine and their potential in vivo functions. Prog. Nucleic Acid Res. Mol. Biol. 68 (2001) 193-205
15. Kennedy M.C., Kent T.A., Emptage M., Merkle H., Beinert H., and Munck E. Evidence for the formation of a linear [3Fe-4S] cluster in partially unfolded aconitase. J. Biol. Chem. 259 (1984) 14463-14471
16. Leatherbarrow R.J. "Enzfitter: A Non-linear Regression Analysis Program for IBM PC." (1987), Elsevier Science, Amsterdam
17. Lee C.Y., Bai H., Houle R., Wilson G.M., and Lu A.-L. An Escherichia coli MutY mutant without the six-helix barrel domain is a dimer in solution and assembles cooperatively into multisubunit complexes with DNA. J. Biol. Chem. 279 (2004) 52653-52663
18. Li L., and Lu A.-L. The C-terminal domain of Escherichia coli MutY is involved in DNA binding and glycosylase activities. Nucleic Acids Res. 31 (2003) 3038-3049
19. Li X., Wright P.M., and Lu A.-L. The C-terminal domain of MutY glycosylase determines the 7,8-dihydro-8-oxo-guanine specificity and is crucial for mutation avoidance. J. Biol. Chem. 275 (2000) 8448-8455
20. Lu A.-L. Repair of A/G and A/8-oxoG mismatches by MutY adenine DNA glycosylase. In: Vaughan P. (Ed). "DNA Repair Protocols, Prokaryotic Systems" (2000), Humana Press, Totowa, NJ 3-16
21. Lu A.-L., and Fawcett W.P. Characterization of the recombinant MutY homolog, an adenine DNA glycosylase, from Schizosacchromyces pombe. J. Biol. Chem. 273 (1998) 25098-25105
22. Lu AL., Li X., Gu Y., Wright P.M., and Chang D.-Y. Repair of oxidative DNA damage. Cell Biochem. Biophy. 35 (2001) 141-170
23. Lu A.-L., Tsai-Wu J.-J., and Cillo J. DNA determinants and substrate specificities of Escherichia coli MutY. J. Biol. Chem. 270 (1995) 23582-23588
24. Lu A.-L., and Wright P.M. Characterization of an Escherichia coli mutant MutY with a cysteine to alanine mutation at the iron-sulfur cluster domain. Biochemistry 42 (2003) 3742-3750
25. Michaels M.L., and Miller J.H. The GO system protects organisms from the mutagenic effect of the spontaneous lesion 8-hydroxyguanine (7,8-dihydro-8-oxo-guanine). J. Bacteriol. 174 (1992) 6321-6325
26. Modrich P., and Lahue R.S. Mismatch repair in replication fidelity, genetic recombination and cancer biology. Annu. Rev. Biochem. 65 (1996) 101-133
27. Parker A., Gu Y., Mahoney W., Lee S.-H., Singh K.K., and Lu A.-L. Human homolog of the MutY protein (hMYH) physically interacts with protein involved in long-patch DNA base excision repair. J. Biol. Chem. 276 (2001) 5547-5555
28. Pope M.A., and David S.S. DNA damage recognition and repair by the murine MutY homologue. DNA Repair (Amst) 4 (2005) 91-102
29. Pope M.A., Porello S.L., and David S.S. Escherichia coli apurinic-apyrimidinic endonucleases enhance the turnover of the adenine glycosylase MutY with G:A substrates. J. Biol. Chem. 277 (2002) 22605-22615
30. Porello S.L., Leyes A.E., and David S.S. Single-turnover and pre-steady-state kinetics of the reaction of the adenine glycosylase MutY with mismatch-containing DNA substrates. Biochemistry 37 (1998) 14756-14764
31. Shiomi Y., Shinozaki A., Nakada D., Sugimoto K., Usukura J., Obuse C., and Tsurimoto T. Clamp and clamp loader structures of the human checkpoint protein complexes, Rad9-1-1 and Rad17-RFC. Genes to Cells 7 (2002) 861-868
32. Tchou J., and Grollman A.P. Repair of DNA containing the oxidatively-damaged base 8-hydroxyguanine. Mutat. Res. 299 (1993) 277-287
33. Tsai-Wu J.-J., Liu H.-F., and Lu A.-L. Escherichia coli MutY protein has both N-glycosylase and apurinic/apyrimidinic endonuclease activities on AṡC and AṡG mispairs. Proc. Natl. Acad. Sci. USA 89 (1992) 8779-8783
34. Venclovas C., and Thelen M.P. Structure-based predictions of Rad1, Rad9, Hus1 and Rad17 participation in sliding clamp and clamp-loading complexes. Nucleic Acids Res. 28 (2000) 2481-2493
35. Wright P.M., Yu J., Cillo J., and Lu A.-L. The active site of the Escherichia coli MutY DNA adenine glycosylase. J. Biol. Chem. 274 (1999) 29011-29018
36. Yang H., Clendenin W.M., Wong D., Demple B., Slupska M.M., Chiang J.H., and Miller J.H. Enhanced activity of adenine-DNA glycosylase (Myh) by apurinic/apyrimidinic endonuclease (Ape1) in mammalian base excision repair of an A/GO mismatch. Nucleic Acids Res. 29 (2001) 743-752
37. Zhou B.B., and Elledge S.J. The DNA damage response: Putting checkpoints in perspective. Nature 408 (2000) 433-439