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Volumn 94, Issue 2, 2006, Pages 263-272

Interpretation of metabolic flux maps by limitation potentials and constrained limitation sensitivities

Author keywords

Flux sensitivity; Limitation potential; Metabolic flux analysis; Metabolic network analysis

Indexed keywords

BIOCHEMISTRY; CONSTRAINT THEORY; METABOLITES; STOICHIOMETRY; SUGARS;

EID: 33744468776     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.20837     Document Type: Article
Times cited : (2)

References (21)
  • 1
    • 0025895183 scopus 로고
    • Towards a science of metabolic engineering
    • Bailey JE. 1991. Towards a science of metabolic engineering. Science 252:1668-1674.
    • (1991) Science , vol.252 , pp. 1668-1674
    • Bailey, J.E.1
  • 2
    • 0031194875 scopus 로고    scopus 로고
    • Inverse flux analysis for reduction of acetate excretion in Escherichia coli
    • Delgado J, Liao JC. 1997. Inverse flux analysis for reduction of acetate excretion in Escherichia coli. Biotechnol Progr 13(4):361-367.
    • (1997) Biotechnol Progr , vol.13 , Issue.4 , pp. 361-367
    • Delgado, J.1    Liao, J.C.2
  • 3
    • 0035125986 scopus 로고    scopus 로고
    • In silico predictions of Escherichia coli metabolic capabilities are consistent with experimental data
    • Edwards JS, Ibarra RU, Palsson BO. 2001. In silico predictions of Escherichia coli metabolic capabilities are consistent with experimental data. Nat Biotechnol 19(2):125-130.
    • (2001) Nat Biotechnol , vol.19 , Issue.2 , pp. 125-130
    • Edwards, J.S.1    Ibarra, R.U.2    Palsson, B.O.3
  • 4
    • 0036001069 scopus 로고    scopus 로고
    • Metabolic modelling of microbes: The flux-balance approach
    • Edwards JS, Covert M, Palsson BO. 2002. Metabolic modelling of microbes: The flux-balance approach. Environ Microbiol 4(3):133-140.
    • (2002) Environ Microbiol , vol.4 , Issue.3 , pp. 133-140
    • Edwards, J.S.1    Covert, M.2    Palsson, B.O.3
  • 5
    • 0038606003 scopus 로고    scopus 로고
    • Production process monitoring by serial mapping of microbial carbon flux distributions using a novel sensor reactor approach: I-Sensor reactor system
    • El Massaoudi M, Spelthahn J, Drysch A, Graaf A, de Takors R. 2003. Production process monitoring by serial mapping of microbial carbon flux distributions using a novel sensor reactor approach: I-Sensor reactor system. Metabol Eng 5(2):86-95.
    • (2003) Metabol Eng , vol.5 , Issue.2 , pp. 86-95
    • El Massaoudi, M.1    Spelthahn, J.2    Drysch, A.3    Graaf, A.4    De Takors, R.5
  • 6
    • 0026802334 scopus 로고
    • Metabolic control analysis - A survey of its theoretical and experimental development
    • Fell DA. 1992. Metabolic control analysis-a survey of its theoretical and experimental development. Biochem J 286:313-330.
    • (1992) Biochem J , vol.286 , pp. 313-330
    • Fell, D.A.1
  • 7
    • 25144492110 scopus 로고    scopus 로고
    • Approximative kinetic formats used in metabolic network modeling
    • Heijnen JJ. 2005. Approximative kinetic formats used in metabolic network modeling. Biotechnol Bioeng 91:534-545.
    • (2005) Biotechnol Bioeng , vol.91 , pp. 534-545
    • Heijnen, J.J.1
  • 8
    • 0030571222 scopus 로고    scopus 로고
    • Pathway analysis, engineering, and physiological considerations for redirecting central metabolism
    • Liao J, Hou S, Chao Y. 1996. Pathway analysis, engineering, and physiological considerations for redirecting central metabolism. Biotechnol Bioeng 52(1):129-140.
    • (1996) Biotechnol Bioeng , vol.52 , Issue.1 , pp. 129-140
    • Liao, J.1    Hou, S.2    Chao, Y.3
  • 9
    • 1642457253 scopus 로고    scopus 로고
    • The effects of alternate optimal solutions in constraint-based genome-scale metabolic models
    • Mahadevan R, Schilling CH. 2003. The effects of alternate optimal solutions in constraint-based genome-scale metabolic models. Metabol Eng 5(4):264-276.
    • (2003) Metabol Eng , vol.5 , Issue.4 , pp. 264-276
    • Mahadevan, R.1    Schilling, C.H.2
  • 12
    • 3242892145 scopus 로고    scopus 로고
    • Fully integrated L-phenylalanine separation and concentration using reactive-extraction with liquid-liquid centrifuges in a fed-batch process with E-coli
    • Rüffer N, Heidersdorf U, Kretzers I, Sprenger GA, Raeven L, Takors R. 2004. Fully integrated L-phenylalanine separation and concentration using reactive-extraction with liquid-liquid centrifuges in a fed-batch process with E-coli. Bioproc Biosyst Eng 26(4):239-248.
    • (2004) Bioproc Biosyst Eng , vol.26 , Issue.4 , pp. 239-248
    • Rüffer, N.1    Heidersdorf, U.2    Kretzers, I.3    Sprenger, G.A.4    Raeven, L.5    Takors, R.6
  • 13
    • 0034447725 scopus 로고    scopus 로고
    • Combining pathway analysis with flux balance analysis for the comprehensive study of metabolic systems
    • Schilling CH, Edwards JS, Letscher D, Palsson BO. 2000. Combining pathway analysis with flux balance analysis for the comprehensive study of metabolic systems. Biotechnol Bioeng 71(4):286-306.
    • (2000) Biotechnol Bioeng , vol.71 , Issue.4 , pp. 286-306
    • Schilling, C.H.1    Edwards, J.S.2    Letscher, D.3    Palsson, B.O.4
  • 16
    • 0031594984 scopus 로고    scopus 로고
    • C-13-NMR, MS and metabolic flux balancing in biotechnology research
    • Szyperski T. 1998. C-13-NMR, MS and metabolic flux balancing in biotechnology research. Q Rev Biophys 31(1):41-106.
    • (1998) Q Rev Biophys , vol.31 , Issue.1 , pp. 41-106
    • Szyperski, T.1
  • 17
    • 0027572102 scopus 로고
    • Metabolic flux distributions in corynebacterium-glutamicum during growth and lysine overproduction
    • Vallino J, Stephanopoulos G. 1993. Metabolic flux distributions in corynebacterium-glutamicum during growth and lysine overproduction. Biotechnol Bioeng 41(6):633-646.
    • (1993) Biotechnol Bioeng , vol.41 , Issue.6 , pp. 633-646
    • Vallino, J.1    Stephanopoulos, G.2
  • 18
    • 0028764687 scopus 로고
    • Linear constraint relations in biochemical reaction systems. 1. Classification of the calculability and the balanceability of conversion rates
    • Vanderheijden R, Heijnen J, Hellinga C, Romein B, Luyben K. 1994. Linear constraint relations in biochemical reaction systems. 1. Classification of the calculability and the balanceability of conversion rates. Biotechnol Bioeng 43(1):3-10.
    • (1994) Biotechnol Bioeng , vol.43 , Issue.1 , pp. 3-10
    • Vanderheijden, R.1    Heijnen, J.2    Hellinga, C.3    Romein, B.4    Luyben, K.5
  • 19
    • 0027223982 scopus 로고
    • Stoichiometric interpretation of Escherichia coli glucose catabolism under various oxygenation rates
    • Varma A, Boesch BW, Palsson BO. 1993. Stoichiometric interpretation of Escherichia coli glucose catabolism under various oxygenation rates. Appl Environ Microbiol 59(8):2465-2473.
    • (1993) Appl Environ Microbiol , vol.59 , Issue.8 , pp. 2465-2473
    • Varma, A.1    Boesch, B.W.2    Palsson, B.O.3
  • 20
    • 2942756043 scopus 로고    scopus 로고
    • Serial C-13-based flux analysis of an L-phenylaianine-producing E-coli strain using the sensor reactor
    • Wahl A, El Massaoudi M, Schipper D, Wiechert W, Takors R. 2004. Serial C-13-based flux analysis of an L-phenylaianine-producing E-coli strain using the sensor reactor. Biotechnol Progr 20(3):706-714.
    • (2004) Biotechnol Progr , vol.20 , Issue.3 , pp. 706-714
    • Wahl, A.1    El Massaoudi, M.2    Schipper, D.3    Wiechert, W.4    Takors, R.5
  • 21
    • 0034741983 scopus 로고    scopus 로고
    • C-13 metabolic flux analysis
    • Wiechert W. 2001. C-13 metabolic flux analysis. Metabol Eng 3(3):195-206.
    • (2001) Metabol Eng , vol.3 , Issue.3 , pp. 195-206
    • Wiechert, W.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.