Temperature dependent gene expression induced by PNIPAM-based copolymers: Potential of hyperthermia in gene transfer

Bioconjugate Chemistry

Volumn 17, Issue 3, 2006, Pages 766-772

  Zintchenko, Arkadi ^a   Ogris, Manfred ^a   Wagner, Ernst ^a  

^a UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACRYLIC MONOMERS; BLOCK COPOLYMERS; EFFICIENCY; GENE TRANSFER; HYDROPHILICITY; MOLECULAR BIOLOGY;

BLOCK CO POLYMERS; GENE DELIVERY VECTORS; GENES EXPRESSION; HIGHER EFFICIENCY; HYDROPHILIC MONOMERS; POLY(ETHYLENEIMINE); POLY(N-ISOPROPYLACRYAMIDE); STATISTICAL COPOLYMERS; TEMPERATURE DEPENDENT; TRANSFECTION EFFICIENCY;

GENE EXPRESSION;

1 VINYL 2 PYRROLIDINONE; ACRYLAMIDE; COPOLYMER; DNA; MONOMER; POLY(N ISOPROPYLACRYLAMIDE); POLYETHYLENEIMINE;

ARTICLE; COMPLEX FORMATION; DRUG FORMULATION; GENE DELIVERY SYSTEM; GENE EXPRESSION; GENETIC TRANSFECTION; HEAT TREATMENT; HYDROPHILICITY; POLYMERIZATION; SURFACE CHARGE; SYNTHESIS; TEMPERATURE DEPENDENCE;

EID: 33646902955     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc050292z     Document Type: Article

References (33)

1. Wagner, E., Kircheis, R., and Walker, G. F. (2004) Targeted nucleic acid deliver into tumors: new avenues for cancer therapy. Biomed. Pharmacother 58, 152-161.
2. Anwer, K., Kao, G., Proctor, B., Anscombe, I., Florack, V., Earls, R., Wilson, E., McCreery, T., Unger, E., Rolland, A., and Sullivan, S. M. (2000) Ultrasound enhancement of cationic lipid-mediated gene transfer to primary tumors following systemic administration. Gene Ther. 7, 1833-1839.
3. Huber, P. E., and Pfisterer, P. (2000) In vitro and in vivo transfection of plasmid DNA in the Dunning prostate tumor R3327-AT1 is enhanced by focused ultrasound. Gene Ther. 7, 1516-1525.
4. Scherer, F., Anton, M., Schillinger, U., Henke, J., Bergemann, C., Kruger A., Gansbacher, B., and Plank, C. (2002) Magnetofection: enhancing and targeting gene delivery by magnetic force in vitro and in vivo. Gene Ther. 9, 102-109.
5. Aihara, H., and Miyazaki, J. (1998) Gene transfer into muscle by electroporation in vivo. Nat. Biotechnol. 16, 867-870.
6. Mathiesen, I. (1999) Electropermeabilization of skeletal muscle enhances gene transfer in vivo. Gene Ther. 6, 508-514.
7. Chang, E., Chalikonda, S., Friedl, J., Xu, H., Phan, G. Q., Marincola, F. M., Alexander, H. R., and Bartlett, D. L. (2005) Targeting vaccinia to solid tumors with local hyperthermia. Hum. Gene Ther. 16, 435-444.
8. Li, C. Y., and Dewhirst, M. W. (2002) Hyperthermia-regulated immunogene therapy. Int. J. Hyperthermia 18, 586-596.
9. Prasmickaite, L., Hogset, A., Tjelle, T. E., Olsen V. M., and Berg, K. (2000) Role of endosomes in gene transfection mediated by photochemical internalisation. J. Gene. Med. 2, 477-488.
10. Kloeckner, J., Prasmickaite, L., Hogset, A., Berg, K., and Wagner, E. (2004) Photochemically enhanced gene delivery of EGF receptor-targeted DNA polyplexes. J. Drug Target. 12, 205-213.
11. Schlemmer, M., Lindner, L. H., Abdel-Rahman, S., and Issels, R. D. (2004) Principles, technology and indication of hyperthermia and part body hyperthermia. Radiologe 44, 301-309.
12. Lindner, L. H., Eichhorn, M. E., Eibl, H., Teichert, N., Schmitt-Sody, M., Issels, R. D., and Dellian, M. (2004) Novel temperature-sensitive liposomes with prolonged circulation time. Clin. Cancer Res. 10, 2168-2178.
13. Kong, G., and Dewhirst, M. W. (1999) Hyperthermia and liposomes. Int. J. Hyperthermia 15, 345-370.
14. Kurisawa, M., Yokoyama, M., and Okano, T. (2000) Transfection efficiency increases by incorporating hydrophobic monomer units into polymeric gene carriers. J. Controlled Release, 68, 1-8.
15. Kurisawa, M., Yokoyama, M., and Okano, T. (2000) Gene expression control by temperature with thermo-responsive polymeric gene carriers. J. Controlled Release 69, 127-137.
16. Sun, S. J., Liu, W. G., Cheng, N., Zhang, B. Q., Cao, Z. Q., Yao, K. D., Liang, D. C., Zuo, A. J., Guo, G., and Zhang, J. Y. (2005) A thermoresponsive chitosan-NIPAAm/vinyl laurate copolymer vector for gene transfection. Bioconjugate Chem. 16, 972-980.
17. Yoshino, K., Kadowaki, A., Takagishi, T., and Kono, K. (2004) Temperature sensitization of liposomes by use of N-isopropylacrylamide copolymers with varying transition endotherms. Bioconjugate Chem. 15, 1102-1109.
18. Yildiz, B., Isik, B., and Kis, M. (2002) Thermoresponsive poly-(N-isopropylacrylamide-co-acrylamide-co-2-hydroxyethyl methacrylate) hydrogels. React. Funct. Polym. 52, 3-10.
19. Siu, M., Zhang, G. Z., and Wu, C. (2002) Effect of comonomer distribution on the coil-to-globule transition of a single AB copolymer chain in dilute solution. Macromolecules 35, 2723-2727.
20. Roux, E., Francis, M., Winnik, F. M., and Leroux, J. C. (2002) Polymer based pH-sensitive carriers as a means to improve the cytoplasmic delivery of drugs. Int. J. Pharm. 242, 25-36.
21. Roux, E., Zignani, M., Daigle, C., Moreau, P., Drummond, D. C., Hong, K., and Leroux J. C. (2000) pH-sensitive gel phase liposomes. Proc. Int. Symp. Controlled Release Bioact. Mater. 27, 215.
22. Plank, C., Zatloukal, K., Gotten, M., Mechtler K., and Wagner, E. (1992) Gene transfer into hepatocytes using asialoglycoprotein receptor mediated endocytosis of DNA complexed with an artificial tetra-antennary galactose ligand. Bioconjugate Chem. 3, 533-539.
23. Snyder, S. L., and Sobocinski, P. Z. (1975) Improved 2,4,6- trinitrobenzenesulfonic acid method for determination of amines. Anal. Biochem. 64, 284-288.
24. von Harpe, A., Petersen, H., Li, Y. X., and Kissel, T. (2000) Characterization of commercially available and synthesized polyethylenimines for gene delivery. J. Controlled Release 69, 309-322.
25. Kircheis, R., Wightman, L., Schreiber, A., Robitza, B., Rossler, V., Kursa, M., and Wagner, E. (2001) Polyethylenimine/DNA complexes shielded by transferrin target gene expression to tumors after systemic application. Gene Ther. 8, 28-40.
26. Kursa, M., Walker, G. F., Roessler, V., Ogris, M., Roedl, W., Kircheis, R., and Wagner, E. (2003) Novel shielded transferrin-polyethylene glycol-polyethylenimine/DNA complexes for systemic tumor-targeted gene transfer. Bioconjugate Chem. 14, 222-231.
27. Feng, X. D., Guo, X. Q., and Qiu, K. Y. (1988) Study of the initiation mechanism of the vinyl polymerization with the system persulfate N, N, N′,N′-tetramethylethylenediamine. Makromol. Chem. 189, 77-83.
28. Guo, X. Q., Qiu, K. Y., and Feng, X. D. (1990) Studies on the kinetics and initiation mechanism of acrylamide polymerization using persulfate aliphatic diamine systems as initiator. Makromol. Chem. 191, 577-587.
29. Mishra, S., Webster, P., and Davis, M. E. (2004) PEGylation significantly affects cellular uptake and intracellular trafficking of nonviral gene delivery particles. Eur. J. Cell Biol. 83, 97-111.
30. Ogris, M., Brunner, S., Schuller, S., Kircheis, R., and Wagner, E. (1999) PEGylated DNA/transferrin-PEI complexes: reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery. Gene Ther. 6, 595-605.
31. Ogris, M., Steinlein, P., Kursa, M., Mechtler, K., Kircheis, R., and Wagner, E. (1998) The size of DNA/transferrin-PEI complexes is an important factor for gene expression in cultured cells. Gene Ther. 5, 1425-1433.
32. Sonawane, N. D., Szoka, F. C., and Verkman, A. S. (2003) Chloride accumulation and swelling in endosomes enhances DNA transfer by polyamine-DNA polyplexes. J. Biol. Chem. 278, 44826-44831.
33. Rejman, J., Bragonzi, A., and Conese, M. (2005) Role of clathrin-and caveolae-mediated endocytosis in gene transfer mediated by lipo- and polyplexes. Mol. Ther. 12, 468-74.