Role of endosomes in gene transfection mediated by photochemical internalisation (PCI)

Journal of Gene Medicine

Volumn 2, Issue 6, 2000, Pages 477-488

  Prasmickaite, Lina ^a   Høgset, Anders ^a   Tjelle, Torunn E ^a   Olsen, Vibeke M ^a   Berg, Kristian ^a  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

Cytosolic delivery; Endocytosis; Gene therapy; Photochemical treatment

Indexed keywords

AMMONIUM CHLORIDE; ANTIINFECTIVE AGENT; BAFILOMYCIN A1; CHLOROQUINE; DNA; GREEN FLUORESCENT PROTEIN; MACROLIDE; PHOTOPROTEIN; RECOMBINANT DNA;

ARTICLE; CELL CULTURE; DRUG EFFECT; ENDOCYTOSIS; ENDOSOME; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; HUMAN; LIGHT; METABOLISM; METHODOLOGY; PHYSIOLOGY; PLASMID; RADIATION EXPOSURE; TEMPERATURE; TIME;

AMMONIUM CHLORIDE; ANTI-BACTERIAL AGENTS; CHLOROQUINE; DNA; DNA, RECOMBINANT; ENDOCYTOSIS; ENDOSOMES; GENE EXPRESSION REGULATION; GREEN FLUORESCENT PROTEINS; HUMANS; LIGHT; LUMINESCENT PROTEINS; MACROLIDES; PLASMIDS; TEMPERATURE; TIME FACTORS; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0347685883     PISSN: 1099498X     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-2254(200011/12)2:6<477::AID-JGM137>3.0.CO;2-B     Document Type: Article

References (47)

1. Anderson WF. Human gene therapy. Science 1992; 256: 808-813.
2. Verma IM, Somia N. Gene therapy - promises, problems and prospects. Nature 1997; 389: 239-242.
3. Blau H, Khavari P. Gene therapy: progress, problems, prospects. Nat Med 1997; 3: 612-613.
4. Robbins PD, Tahara H, Ghivizzani SC. Viral vectors for gene therapy. Trends Biotechnol 1998; 16: 35-40.
5. Ledley FD. Nonviral gene therapy: the promise of genes as pharmaceutical products. Hum Gene Ther 1995; 6: 1129-1144.
6. Emi N, Kidoaki S, Yoshikawa K, et al. Gene transfer mediated by polyarginine requires a formation of big carrier-complex of DNA aggregate. Biochem Biophys Res Commun 1997; 231: 421-424.
7. Leonetti JP, Degols G, Lebleu B. Biological activity of oligonucleotide-poly(L-lysine) conjugates: mechanism of cell uptake. Bioconjug Chem 1990; 1: 149-153.
8. Lee RJ, Huang L. Lipidic vector systems for gene transfer. Crit Rev Ther Drug Carrier Syst 1997; 14: 173-206.
9. Zhou X, Huang L. DNA transfection mediated by cationic liposomes containing lipopolylysine: characterization and mechanism of action. Biochim Biophys Acta 1994; 1189: 195-203.
10. Zabner J, Fasbender AJ, Moninger T, et al. Cellular and molecular barriers to gene transfer by a cationic lipid. J Biol Chem 1995; 270: 18997-19007.
11. Friend DS, Papahadjopoulos D, Debs RJ. Endocytosis and intracellular processing accompanying transfection mediated by cationic liposomes. Biochim Biophys Acta 1996; 1278: 41-50.
12. Plank C, Oberhauser B, Mechtler K, et al. The influence of endosome-disruptive peptides on gene transfer using synthetic virus-like gene transfer systems. J Biol Chem 1994; 269: 12918-12924.
13. Midoux P, Mendes C, Legrand A, et al. Specific gene transfer mediated by lactosylated poly-L-lysine into hepatoma cells. Nucleic Acids Res 1993; 21: 871-878.
14. Bongartz JP, Aubertin AM, Milhaud PG, et al. Improved biological activity of antisense oligonucleotides conjugated to a fusogenic peptide. Nucleic Acids Res 1994; 22: 4681-4688.
15. Wagner E, Zatloukal K, Cotten M, et al. Coupling of adenovirus to transferrin-polylysine/DNA complexes greatly enhances receptor-mediated gene delivery and expression of transfected genes. Proc Natl Acad Sci U S A 1992; 89: 6099-6103.
16. Erbacher P, Roche AC, Monsigny M, et al. Putative role of chloroquine in gene transfer into a human hepatoma cell line by DNA/lactosylated polylysine complexes. Exp Cell Res 1996; 225: 186-194.
17. Zauner W, Kichler A, Schmidt W, et al. Glycerol and polylysine synergize in their ability to rupture vesicular membranes: a mechanism for increased transferrin-polylysine-mediated gene transfer. Exp Cell Res 1997; 232: 137-145.
18. Farhood H, Serbina N, Huang L. The role of dioleoyl phosphatidylethanolamine in cationic liposome mediated gene transfer. Biochim Biophys Acta 1995; 1235: 289-295.
19. Xu Y, Szoka FC. Mechanism of DNA release from cationic liposome/DNA complexes used in cell transfection. Biochemistry 1996; 35: 5616-5623.
20. Zelphati O, Szoka FC. Mechanism of oligonucleotide release from cationic liposomes. Proc Natl Acad Sci U S A 1996; 93: 11493-11498.
21. Stegmann T, Legendre JY. Gene transfer mediated by cationic lipids: lack of a correlation between lipid mixing and transfection. Biochim Biophys Acta 1997; 1325: 71-79.
22. Wattiaux R, Jadot M, Laurent N, et al. Cationic lipids delay the transfer of plasmid DNA to lysosomes. Biochem Biophys Res Commun 1996; 227: 448-454.
23. Laurent N, Wattiaux-De Coninck S, Mihaylova E, et al. Uptake by rat liver and intracellular fate of plasmid DNA complexed with poly-L-lysine or poly-D-lysine. FEBS Lett 1999; 443: 61-65.
24. Vitiello L, Chonn A, Wasserman JD, et al. Condensation of plasmid DNA with polylysine improves liposome-mediated gene transfer into established and primary muscle cells. Gene Ther 1996; 3: 396-404.
25. Zauner W, Brunner S, Buschle M, et al. Differential behaviour of lipid based and polycation based gene transfer systems in transfecting primary human fibroblasts: a potential role of polylysine in nuclear transport. Biochim Biophys Acta 1999; 1428: 57-67.
26. Berg K, Selbo PK, Prasmickaite L, et al. Photochemical internalization: a novel technology for delivery of macromolecules into cytosol. Cancer Res 1999; 59: 1180-1183.
27. Berg K, Moan J. Lysosomes and microtubules as targets for photochemotherapy of cancer. Photochem Photobiol 1997; 65: 403-409.
28. Berg K, Moan J. Lysosomes as photochemical targets. Int J Cancer 1994; 59: 814-822.
29. Høgset A, Prasmickaite L, Tjelle TE, et al. Photochemical transfection: a new technology for light-induced, site-directed gene delivery. Hum Gene Ther 2000; 11: 869-880.
30. Aamdal S, Fodstad O, Kaalhus O, et al. Chemosensitivity profiles of human cancers assessed by the 6-day SRC assay on serially xenografted tumors. Int J Cancer 1986; 37: 579-587.
31. Rodal GH, Rodal SK, Moan J, et al. Liposome-bound Zn (II)-phthalocyanine. Mechanisms for cellular uptake and photosensitization. J Photochem Photobiol 1998; 45: 150-159.
32. Boussif O, Lezoualc'h F, Zanta MA, et al. A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine. Proc Natl Acad Sci U S A 1995; 92: 7297-7301.
33. Tseng WC, Haselton FR, Giorgio TD. Transfection by cationic liposomes using simultaneous single cell measurements of plasmid delivery and transgene expression. J Biol Chem 1997; 272: 25641-25647.
34. Marsh M. The entry of enveloped viruses into cells by endocytosis. Biochem J 1984; 218: 1-10.
35. Wagner E, Zenke M, Cotten M, et al. Transferrin-polycation conjugates as carriers for DNA uptake into cells. Proc Natl Acad Sci U S A 1990; 87: 3410-3414.
36. Maxfield FR. Weak bases and ionophores rapidly and reversibly raise the pH of endocytic vesicles in cultured mouse fibroblasts. J Cell Biol 1982; 95: 676-681.
37. Gao X, Huang L. Cationic liposome-mediated gene transfer. Gene Ther 1995; 2: 710-722.
38. Clague MJ, Urbe S, Aniento F, et al. Vacuolar ATPase activity is required for endosomal carrier vesicle formation. J Biol Chem 1994; 269: 21-24.
39. van Deurs B, Holm PK, Sandvig K. Inhibition of the vacuolar H(+)-ATPase with bafilomycin reduces delivery of internalized molecules from mature multivesicular endosomes to lysosomes in HEp-2 cells. Eur J Cell Biol 1996; 69: 343-350.
40. Yoshimori T, Yamamoto A, Moriyama Y, et al. Bafilomycin A1, a specific inhibitor of vacuolar-type H(+)-ATPase, inhibits acidification and protein degradation in lysosomes of cultured cells. J Biol Chem 1991; 266: 17707-17712.
41. Erbacher P, Bousser MT, Raimond J, et al. Gene transfer by DNA/glycosylated polylysine complexes into human blood monocyte-derived macrophages. Hum Gene Ther 1996; 7: 721-729.
42. Dunn WA, Hubbard AL, Aronson NN. Low temperature selectively inhibits fusion between pinocytic vesicles and lysosomes during heterophagy of 125I-asialofetuin by the perfused rat liver. J Biol Chem 1980; 255: 5971-5978.
43. van Weert AW, Dunn KW, Gueze HJ, et al. Transport from late endosomes to lysosomes, but not sorting of integral membrane proteins in endosomes, depends on the vacuolar proton pump. J Cell Biol 1995; 130: 821-834.
44. Leopold PL, Ferris B, Grinberg I, et al. Fluorescent virions: dynamic tracking of the pathway of adenoviral gene transfer vectors in living cells. Hum Gene Ther 1998; 9: 367-378.
45. Pollard H, Remy JS, Loussouarn G, et al. Polyethylenimine but not cationic lipids promotes transgene delivery to the nucleus in mammalian cells. J Biol Chem 1998; 273: 7507-7511.
46. Tseng WC, Haselton FR, Giorgio TD. Mitosis enhances transgene expression of plasmid delivered by cationic liposomes. Biochim Biophys Acta 1999; 1445: 53-64.
47. Berg K, Moan J. Mitotic inhibition by phenylporphines and tetrasulfonated aluminium phthalocyanine in combination with light. Photochem Photobiol 1992; 56: 333-339.