Assorted effects of TGFβ and chondroitinsulfate on p38 and ERK1/2 activation levels in human articular chondrocytes stimulated with LPS

Osteoarthritis and Cartilage

Volumn 14, Issue 6, 2006, Pages 519-525

  Holzmann, J ^a   Brandl, N ^a   Zemann, A ^a   Schabus, R ^b   Marlovits, S ^b   Cowburn, R ^c   Huettinger, M ^a  

^a Department of Pathophysiology   (Austria)

^b GENERAL HOSPITAL   (Austria)

^c KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Chondrocyte; Chondroitinsulfate; ERK1 2; LPS; Metalloproteinases; p38; Signal transduction; TGF

Indexed keywords

CHONDROITIN SULFATE; COLLAGENASE 3; GELATINASE A; LIPOPOLYSACCHARIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; STROMELYSIN; TRANSFORMING GROWTH FACTOR BETA; COLLAGENASE; MITOGEN ACTIVATED PROTEIN KINASE; MMP13 PROTEIN, HUMAN;

ARTICLE; ARTICULAR CARTILAGE; CARTILAGE CELL; CELL METABOLISM; CELL STIMULATION; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFICACY; DRUG MECHANISM; DRUG TARGETING; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FEEDBACK SYSTEM; HUMAN; HUMAN CELL; HYPOTHESIS; IMMUNOBLOTTING; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; CELL CULTURE; CYTOLOGY; ENZYMOLOGY; GENE EXPRESSION; METABOLISM; PHYSIOLOGY;

CARTILAGE, ARTICULAR; CELLS, CULTURED; CHONDROCYTES; CHONDROITIN SULFATES; COLLAGENASES; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION; HUMANS; LIPOPOLYSACCHARIDES; MATRIX METALLOPROTEINASE 13; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 3; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; P38 MITOGEN-ACTIVATED PROTEIN KINASES; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA;

EID: 33646874427     PISSN: 10634584     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.joca.2005.12.005     Document Type: Article

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