Differential patterns of response to doxycycline and transforming growth factor β1 in the down-regulation of collagenases in osteoarthritic and normal human chondrocytes

Arthritis and Rheumatism

Volumn 42, Issue 4, 1999, Pages 719-727

  Shlopov, Boris V ^a,d   Smith Jr , Gerald N ^b   Cole, Ada A ^c   Hasty, Karen A ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c RUSH UNIVERSITY MEDICAL CENTER   (United States)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGENASE; DOXYCYCLINE; MESSENGER RNA; NEUTROPHIL COLLAGENASE; PHORBOL 13 ACETATE 12 MYRISTATE; TRANSFORMING GROWTH FACTOR BETA1;

ADULT; AGED; ARTICLE; CARTILAGE CELL; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG RESPONSE; ENZYME ANALYSIS; ENZYME REGULATION; ENZYME SYNTHESIS; HUMAN; HUMAN TISSUE; OSTEOARTHRITIS; PRIORITY JOURNAL;

AGED; ANTI-BACTERIAL AGENTS; BLOTTING, NORTHERN; BLOTTING, WESTERN; CARCINOGENS; CELLS, CULTURED; CHONDROCYTES; COLLAGENASES; DOXYCYCLINE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MATRIX METALLOPROTEINASE 1; MATRIX METALLOPROTEINASE 13; MATRIX METALLOPROTEINASE 8; MIDDLE AGED; OSTEOARTHRITIS; RNA, MESSENGER; SYNOVIAL MEMBRANE; TETRADECANOYLPHORBOL ACETATE; TRANSFORMING GROWTH FACTOR BETA;

EID: 0032908329     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/1529-0131(199904)42:4<719::AID-ANR15>3.0.CO;2-T     Document Type: Article

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