메뉴 건너뛰기




Volumn 82, Issue 967, 2006, Pages 338-342

Clinical outcome of patients with Helicobacter pylori infection: The bug, the host, or the environment?

Author keywords

[No Author keywords available]

Indexed keywords

ADHESIN; CAGA PROTEIN; HEAT SHOCK PROTEIN 60; INTERLEUKIN 8; METAL; UREASE; VACUOLATING TOXIN;

EID: 33646873252     PISSN: 00325473     EISSN: None     Source Type: Journal    
DOI: 10.1136/pgmj.2005.038273     Document Type: Review
Times cited : (26)

References (51)
  • 1
    • 0030344912 scopus 로고    scopus 로고
    • Helicobacter pylori infection, a paradigm for chronic mucosal inflammation: Pathogenesis and implications for eradication and prevention
    • Cover TL, Blaser MJ. Helicobacter pylori infection, a paradigm for chronic mucosal inflammation: pathogenesis and implications for eradication and prevention. Adv Int Med 1996;41:85-117.
    • (1996) Adv Int Med , vol.41 , pp. 85-117
    • Cover, T.L.1    Blaser, M.J.2
  • 2
    • 0030835739 scopus 로고    scopus 로고
    • The complete genome sequence of the gastric pathogen Helicobacter pylori
    • Tomb JF, White O, Kerlavage AR, et al. The complete genome sequence of the gastric pathogen Helicobacter pylori. Nature 1997;388:539-47.
    • (1997) Nature , vol.388 , pp. 539-547
    • Tomb, J.F.1    White, O.2    Kerlavage, A.R.3
  • 3
    • 0033552961 scopus 로고    scopus 로고
    • Genomic sequence comparison of two unrelated isolates of the human gastric pathogen Helicobacter pylori
    • Alm RA, Ling LS, Moir DT, et al. Genomic sequence comparison of two unrelated isolates of the human gastric pathogen Helicobacter pylori. Nature 1999;397:176-80.
    • (1999) Nature , vol.397 , pp. 176-180
    • Alm, R.A.1    Ling, L.S.2    Moir, D.T.3
  • 4
    • 0036128606 scopus 로고    scopus 로고
    • Helicobacter pylori uses motility for initial colonization and to attain robust infection
    • Ottemann MK, Lowenthal AK. Helicobacter pylori uses motility for initial colonization and to attain robust infection. Infect Immun 2002;70:1984-90.
    • (2002) Infect Immun , vol.70 , pp. 1984-1990
    • Ottemann, M.K.1    Lowenthal, A.K.2
  • 5
    • 0029086241 scopus 로고
    • Inability of an isogenic urease negative mutant strain of Helicobacter mustelae to colonize me ferret stomach
    • Andrutis KA, Fox JG, Schauer DB, et al. Inability of an isogenic urease negative mutant strain of Helicobacter mustelae to colonize me ferret stomach. Infect Immun 1995;63:3722-5.
    • (1995) Infect Immun , vol.63 , pp. 3722-3725
    • Andrutis, K.A.1    Fox, J.G.2    Schauer, D.B.3
  • 6
    • 0033846363 scopus 로고    scopus 로고
    • Local pH elevation mediated by the intrabacterial urease of Helicobacter pylori cocultured with gastric cells
    • Athmann C, Zeng N, Kang T, et al. Local pH elevation mediated by the intrabacterial urease of Helicobacter pylori cocultured with gastric cells. J Clin Invest 2000;106:339-47.
    • (2000) J Clin Invest , vol.106 , pp. 339-347
    • Athmann, C.1    Zeng, N.2    Kang, T.3
  • 7
    • 0031658740 scopus 로고    scopus 로고
    • Influence of pH on metabolism and urease activity of Helicobacter pylori
    • Rektorschek M, Weeks D, Sachs G, et al. Influence of pH on metabolism and urease activity of Helicobacter pylori. Gastroenterology 1998;115:628-41.
    • (1998) Gastroenterology , vol.115 , pp. 628-641
    • Rektorschek, M.1    Weeks, D.2    Sachs, G.3
  • 8
    • 0033958917 scopus 로고    scopus 로고
    • Expression of the Hp urel gene is required for acidic pH activation of cytoplasmic urease
    • Scott DR, Marcus EA, Weeks DL, et al. Expression of the Hp urel gene is required for acidic pH activation of cytoplasmic urease. Infect Immun 2000;68:470-7
    • (2000) Infect Immun , vol.68 , pp. 470-477
    • Scott, D.R.1    Marcus, E.A.2    Weeks, D.L.3
  • 9
    • 0030034805 scopus 로고    scopus 로고
    • Helicobacter pylori attachment to gastric cells induces cytoskeletal rearrangements and tyrosine phosphorylahon of host cell proteins
    • Segal ED, Falkow S, Tomkins LS. Helicobacter pylori attachment to gastric cells induces cytoskeletal rearrangements and tyrosine phosphorylahon of host cell proteins. Proc Natl Acad Sci U S A 1996;93:1259-64.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 1259-1264
    • Segal, E.D.1    Falkow, S.2    Tomkins, L.S.3
  • 10
    • 0032960698 scopus 로고    scopus 로고
    • Mechanisms of Helicobacter pylori infection; bacterial factors
    • Mc Gee DJ, Mobley HL. Mechanisms of Helicobacter pylori infection; bacterial factors. Curr Top Microbiol Immunol 1999;241:155-80.
    • (1999) Curr Top Microbiol Immunol , vol.241 , pp. 155-180
    • Mc Gee, D.J.1    Mobley, H.L.2
  • 11
    • 0030772159 scopus 로고    scopus 로고
    • Helicobacter pylori infection activates NF-kappaB in gastric epithelial cells
    • Keates S, Hitti YS, Upton M, et al. Helicobacter pylori infection activates NF-kappaB in gastric epithelial cells. Gastroenterology 1997;113:1099-109.
    • (1997) Gastroenterology , vol.113 , pp. 1099-1109
    • Keates, S.1    Hitti, Y.S.2    Upton, M.3
  • 12
    • 0033607258 scopus 로고    scopus 로고
    • Clinical relevance of the Helicobacter pylori gene for blood group antigen-binding adhesin
    • Gerhard M, Lehn N, Neumayer N, et al. clinical relevance of the Helicobacter pylori gene for blood group antigen-binding adhesin. Proc Natl Acad Sci U S A 1999;96:12778-83
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 12778-12783
    • Gerhard, M.1    Lehn, N.2    Neumayer, N.3
  • 13
    • 0032983194 scopus 로고    scopus 로고
    • Genetic and functional characterization of the alpAB gene locus essential for the adhesion of Helicobacter pylori to human gastric tissue
    • Odenbreit S, Till M, Hofreuter D, et al. Genetic and functional characterization of the alpAB gene locus essential for the adhesion of Helicobacter pylori to human gastric tissue. Mol Microbiol 1999;31:1537-48.
    • (1999) Mol Microbiol , vol.31 , pp. 1537-1548
    • Odenbreit, S.1    Till, M.2    Hofreuter, D.3
  • 14
    • 0037178771 scopus 로고    scopus 로고
    • Helicobacter pylori SabA adhesin in persistent infection and chronic inflammation
    • Mandavi J, Sonden B, Hurtig, et al. Helicobacter pylori SabA adhesin in persistent infection and chronic inflammation. Science 2002;297:573-8.
    • (2002) Science , vol.297 , pp. 573-578
    • Mandavi, J.1    Sonden, B.2    Hurtig3
  • 15
    • 0032587295 scopus 로고    scopus 로고
    • Helicobacter pylori heat shock protein A: Serologic responses and genetic diversity
    • Ng EKW, Thompson SA, Pérez-Pérez GI, et al. Helicobacter pylori heat shock protein A: serologic responses and genetic diversity. Clin Diagn Lab Immun 1999;6:377-82.
    • (1999) Clin Diagn Lab Immun , vol.6 , pp. 377-382
    • Ng, E.K.W.1    Thompson, S.A.2    Pérez-Pérez, G.I.3
  • 16
    • 0033007931 scopus 로고    scopus 로고
    • Antibodies to human gastric epithelial cells and heat shock protein 60 in Helicobacter pylori positive mucosa associated lymphoid tissue lymphoma
    • Kawahara Y, Yokota K, Mizuno M, et al. Antibodies to human gastric epithelial cells and heat shock protein 60 in Helicobacter pylori positive mucosa associated lymphoid tissue lymphoma. Gut 1999;45:20-3.
    • (1999) Gut , vol.45 , pp. 20-23
    • Kawahara, Y.1    Yokota, K.2    Mizuno, M.3
  • 17
    • 0034767124 scopus 로고    scopus 로고
    • Immunoglobulin G1 antibody response to Helicobacter pylori heat shock protein 60 is closely associated with low-grade gastric mucosa-associated lymphoid tissue lymphoma
    • Yamaguchi H, Osaki T, Kai M, et al. Immunoglobulin G1 antibody response to Helicobacter pylori heat shock protein 60 is closely associated with low-grade gastric mucosa-associated lymphoid tissue lymphoma. Clin Diagn Lab Immun 2001;8:1056-9.
    • (2001) Clin Diagn Lab Immun , vol.8 , pp. 1056-1059
    • Yamaguchi, H.1    Osaki, T.2    Kai, M.3
  • 18
    • 0344172832 scopus 로고    scopus 로고
    • Opening the iron-box: Transcriptional metalloregulation by the fur protein
    • Escolar L, Perez-Martin J, de Lorenzo V. Opening the iron-box: transcriptional metalloregulation by the Fur protein. J Bacteriol 1999;181:6223-9.
    • (1999) J Bacteriol , vol.181 , pp. 6223-6229
    • Escolar, L.1    Perez-Martin, J.2    De Lorenzo, V.3
  • 19
    • 0036084419 scopus 로고    scopus 로고
    • Essential role of ferritin Pfr in Helicobacter pylori iron metabolism and gastric colonization
    • Waidner B, Greiner S, Odenbreit S, et al. Essential role of ferritin Pfr in Helicobacter pylori iron metabolism and gastric colonization. Infect Immun 2002;70:3923-9.
    • (2002) Infect Immun , vol.70 , pp. 3923-3929
    • Waidner, B.1    Greiner, S.2    Odenbreit, S.3
  • 20
    • 0033799935 scopus 로고    scopus 로고
    • Acute gastritis with hypochlorhydria: Report of 35 cases with long term follow up
    • Harford WV, Barnett C, Lee E, et al. Acute gastritis with hypochlorhydria: report of 35 cases with long term follow up. Gut 2000;47:467-72.
    • (2000) Gut , vol.47 , pp. 467-472
    • Harford, W.V.1    Barnett, C.2    Lee, E.3
  • 22
    • 0036271268 scopus 로고    scopus 로고
    • Oxidative-stress resistance mutants of Helicobacter pylori
    • Olczak AA, Olson JW, Maier RJ. Oxidative-stress resistance mutants of Helicobacter pylori. J Bacteriol 2002;184:3186-93.
    • (2002) J Bacteriol , vol.184 , pp. 3186-3193
    • Olczak, A.A.1    Olson, J.W.2    Maier, R.J.3
  • 23
    • 0031839083 scopus 로고    scopus 로고
    • Chemokines in the gastric mucosa in Helicobacter pylori infection
    • Yamaoka Y, Kita M, Kodama T, et al. Chemokines in the gastric mucosa in Helicobacter pylori infection. Gut 1998;42:609-17.
    • (1998) Gut , vol.42 , pp. 609-617
    • Yamaoka, Y.1    Kita, M.2    Kodama, T.3
  • 24
    • 0033591290 scopus 로고    scopus 로고
    • Helicobacter pylori virulence and genetic geography
    • Covacci A, Telford JL, DelGiudice G, et al. Helicobacter pylori virulence and genetic geography. Science 1999;284:1328-33.
    • (1999) Science , vol.284 , pp. 1328-1333
    • Covacci, A.1    Telford, J.L.2    Delgiudice, G.3
  • 25
    • 0345222477 scopus 로고    scopus 로고
    • The interrelationship between Helicobacter pylori vacuolating cytotoxin and gastric carcinoma
    • de Figueiredo Soares T, de Magalhaes Queiroz DM, Mendes EN, et al. The interrelationship between Helicobacter pylori vacuolating cytotoxin and gastric carcinoma. Am J Gastroenterol 1998;93:1841-7.
    • (1998) Am J Gastroenterol , vol.93 , pp. 1841-1847
    • De Figueiredo Soares, T.1    De Magalhaes Queiroz, D.M.2    Mendes, E.N.3
  • 26
    • 0031927042 scopus 로고    scopus 로고
    • Frequency of vacA genotypes and cytotoxin activity in Helicobacter pylori associated with low-grade gastric mucosa associated lymphoid tissue lymphoma
    • Miehlke S, Meining A, Morgner A, et al. Frequency of vacA genotypes and cytotoxin activity in Helicobacter pylori associated with low-grade gastric mucosa associated lymphoid tissue lymphoma. J Clin Microbiol 1998;36:2369-70.
    • (1998) J Clin Microbiol , vol.36 , pp. 2369-2370
    • Miehlke, S.1    Meining, A.2    Morgner, A.3
  • 27
    • 13144253096 scopus 로고    scopus 로고
    • The m2 form of the Helicobacter pylori cytotoxin has cell type specific vacuolating activity
    • Pagliaccia C, de Bernard M, Lupetti P, et al. The m2 form of the Helicobacter pylori cytotoxin has cell type specific vacuolating activity. Proc Natl Acad Sci U S A 1998;95:10212-17.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 10212-10217
    • Pagliaccia, C.1    De Bernard, M.2    Lupetti, P.3
  • 28
    • 0032253792 scopus 로고    scopus 로고
    • Relationship of vacA genotypes of Helicobacter pylori to cagA status, cytotoxin production, and clinical outcome
    • Yamaoka Y, Kodama T, Kita M, et al. Relationship of vacA genotypes of Helicobacter pylori to cagA status, cytotoxin production, and clinical outcome. Helicobacter 1998;4:241-53.
    • (1998) Helicobacter , vol.4 , pp. 241-253
    • Yamaoka, Y.1    Kodama, T.2    Kita, M.3
  • 29
    • 0031741917 scopus 로고    scopus 로고
    • Identification of the Helicobacter pylori vacA toxin domain active in the cell cytosol
    • de Bernard M, Burroni D, Papini E, et al. Identification of the Helicobacter pylori vacA toxin domain active in the cell cytosol. Infect Immun 1998;66:6014-16.
    • (1998) Infect Immun , vol.66 , pp. 6014-6016
    • De Bernard, M.1    Burroni, D.2    Papini, E.3
  • 30
    • 0032528956 scopus 로고    scopus 로고
    • Selective increase of the permeability of polarized epithelial cell monolayers by Helicobacter pylori vacuolating toxin
    • Papini E, Satin B, Norais N, et al. Selective increase of the permeability of polarized epithelial cell monolayers by Helicobacter pylori vacuolating toxin. J Clin Invest 1998;102:813-20.
    • (1998) J Clin Invest , vol.102 , pp. 813-820
    • Papini, E.1    Satin, B.2    Norais, N.3
  • 31
    • 0032795772 scopus 로고    scopus 로고
    • A genetic basis for atrophy: Dominant non-responsiveness and Helicobacter induced gastritis in F1 hybrid mice
    • Sutton P, Wilson J, Genta R, et al. A genetic basis for atrophy: dominant non-responsiveness and Helicobacter induced gastritis in F1 hybrid mice. Gut 1999;45:335-40.
    • (1999) Gut , vol.45 , pp. 335-340
    • Sutton, P.1    Wilson, J.2    Genta, R.3
  • 32
    • 0036197721 scopus 로고    scopus 로고
    • The neutrophil-activating protein of Helicobacter pylori
    • Dundon WG, Nishioka H, Polenghi A, et al. The neutrophil-activating protein of Helicobacter pylori. Int J Med Microbiol 2002;291:545-50.
    • (2002) Int J Med Microbiol , vol.291 , pp. 545-550
    • Dundon, W.G.1    Nishioka, H.2    Polenghi, A.3
  • 33
    • 0029963677 scopus 로고    scopus 로고
    • CagA pathogenicity island of Helicobacter pylori encodes type-I specific and disease associated virulence factors
    • Censini S, Lange C, Xiang Z, et al. CagA pathogenicity island of Helicobacter pylori encodes type-I specific and disease associated virulence factors. Proc Natl Acad Sci U S A 1996;93:14648-53.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 14648-14653
    • Censini, S.1    Lange, C.2    Xiang, Z.3
  • 34
    • 0033615661 scopus 로고    scopus 로고
    • Activation of activator protein 1 and stress response kinases in epithelial cells colonized by Helicobacter pylori encoding the cag pathogenicity island
    • Naumann M, Wessler S, Bartsch C, et al. Activation of activator protein 1 and stress response kinases in epithelial cells colonized by Helicobacter pylori encoding the cag pathogenicity island. J Biol Chem 1999;274:31655-62.
    • (1999) J Biol Chem , vol.274 , pp. 31655-31662
    • Naumann, M.1    Wessler, S.2    Bartsch, C.3
  • 35
    • 0032587923 scopus 로고    scopus 로고
    • Relationship between Helicobacter pylori iceA, cagA, and vacA status and clinical outcome: Studies in four different countries
    • Yamaoka Y, Kodama T, Gutierrez O, et al. Relationship between Helicobacter pylori iceA, cagA, and vacA status and clinical outcome: studies in four different countries. J Clin Microbiol 1999;37:2274-9.
    • (1999) J Clin Microbiol , vol.37 , pp. 2274-2279
    • Yamaoka, Y.1    Kodama, T.2    Gutierrez, O.3
  • 36
    • 0031750247 scopus 로고    scopus 로고
    • Clinical relevance of cagA, vacA and iceA status of Helicobacter pylori
    • van Doorn LJ, Figueiredo C, Sanna R, et al. Clinical relevance of cagA, vacA and iceA status of Helicobacter pylori. Gastroenterology 1998;115:58-66.
    • (1998) Gastroenterology , vol.115 , pp. 58-66
    • Van Doorn, L.J.1    Figueiredo, C.2    Sanna, R.3
  • 37
    • 0033963843 scopus 로고    scopus 로고
    • Evaluation of the clinical relevance of the iceA1 gene in patients with Helicobacter pylori infection in Japan
    • Nishiya D, Shimoyama T, Fukuda S, et al. Evaluation of the clinical relevance of the iceA1 gene in patients with Helicobacter pylori infection in Japan. Scand J Gastroenterol 2000;35:36-9.
    • (2000) Scand J Gastroenterol , vol.35 , pp. 36-39
    • Nishiya, D.1    Shimoyama, T.2    Fukuda, S.3
  • 38
    • 0032774855 scopus 로고    scopus 로고
    • Host, heredity and helicobacter
    • Nedrud JG, Czinn SJ. Host, heredity and helicobacter. Gut 1999;45:323-4.
    • (1999) Gut , vol.45 , pp. 323-324
    • Nedrud, J.G.1    Czinn, S.J.2
  • 39
    • 0012218357 scopus 로고    scopus 로고
    • Disease specific Helicobacter pylori virulence factors; the unfulfilled promise
    • Graham, Yamaoka Y. Disease specific Helicobacter pylori virulence factors; the unfulfilled promise. Aliment Pharm Ther 2000;5(suppl 1):S3-9.
    • (2000) Aliment Pharm Ther , vol.5 , Issue.SUPPL. 1
    • Graham1    Yamaoka, Y.2
  • 40
    • 0026669803 scopus 로고
    • Helicobacter pylori in Hispanics: Comparison with blacks and whites of similar age and socioeconomic class
    • Malaty HM, Evans DG, Evans DJ, et al. Helicobacter pylori in Hispanics: comparison with blacks and whites of similar age and socioeconomic class. Gastroenterology 1992;103:813-16.
    • (1992) Gastroenterology , vol.103 , pp. 813-816
    • Malaty, H.M.1    Evans, D.G.2    Evans, D.J.3
  • 41
    • 0030823022 scopus 로고    scopus 로고
    • Racial differences in Helicobacter pylori seroprevalence in Singapore: Correlation with differences in peptic ulcer frequency
    • Kang JY, Yeoh KJ, Ho KY, et al. Racial differences in Helicobacter pylori seroprevalence in Singapore: correlation with differences in peptic ulcer frequency. J Gastroenterol Hepatol 1997;12:655-9.
    • (1997) J Gastroenterol Hepatol , vol.12 , pp. 655-659
    • Kang, J.Y.1    Yeoh, K.J.2    Ho, K.Y.3
  • 42
    • 0028243163 scopus 로고
    • Helicobacter pylori infection: Genetic and environmental influences. A study of twins
    • Malaty HM, Engstrand L, Pedersen NL, et al. Helicobacter pylori infection: genetic and environmental influences. A study of twins. Ann Intern Med 1994;120:982-6.
    • (1994) Ann Intern Med , vol.120 , pp. 982-986
    • Malaty, H.M.1    Engstrand, L.2    Pedersen, N.L.3
  • 43
    • 0031929342 scopus 로고    scopus 로고
    • Is there significant variation in the risk of gastric cancer associated with Helicobacter pylori infection?
    • Forman G. Is there significant variation in the risk of gastric cancer associated with Helicobacter pylori infection? Aliment Pharm Ther 1998;12(suppl 1):3-7.
    • (1998) Aliment Pharm Ther , vol.12 , Issue.SUPPL. 1 , pp. 3-7
    • Forman, G.1
  • 44
    • 0029925994 scopus 로고    scopus 로고
    • Helicobacter pylori and disturbance of gastric function associated with duodenal ulcer disease and gastric cancer
    • McColl KEL, El-Omar E. Helicobacter pylori and disturbance of gastric function associated with duodenal ulcer disease and gastric cancer. Scand J Gastroenterol 1996;31(suppl 215):32-7.
    • (1996) Scand J Gastroenterol , vol.31 , Issue.SUPPL. 215 , pp. 32-37
    • Kel, M.1    El-Omar, E.2
  • 45
    • 0035856015 scopus 로고    scopus 로고
    • Helicobacter pylori- not a good bug after all
    • Fox JG, Wang TC. Helicobacter pylori- not a good bug after all. N Engl J Med 2001;345:829-32.
    • (2001) N Engl J Med , vol.345 , pp. 829-832
    • Fox, J.G.1    Wang, T.C.2
  • 46
    • 0033960131 scopus 로고    scopus 로고
    • Synergistic interaction between hypergastrinaemia and Helicobacter infection in a mouse model of gastric cancer
    • Wang TC, Dangler CA, Chen D, et al. Synergistic interaction between hypergastrinaemia and Helicobacter infection in a mouse model of gastric cancer. Gastroenterology 2000;118:36-47.
    • (2000) Gastroenterology , vol.118 , pp. 36-47
    • Wang, T.C.1    Dangler, C.A.2    Chen, D.3
  • 47
    • 0034704880 scopus 로고    scopus 로고
    • Interleukin-1 polymorphisms associated with increased risk of gastric cancer
    • El-Omar EM, Carrington M, Chow WII, et al. Interleukin-1 polymorphisms associated with increased risk of gastric cancer. Nature 2000;404:398-402.
    • (2000) Nature , vol.404 , pp. 398-402
    • El-Omar, E.M.1    Carrington, M.2    Chow, W.I.I.3
  • 48
    • 0030775979 scopus 로고    scopus 로고
    • Helicobacter pylori infection in the pathogenesis of duodenal ulcer and gastric cancer: A model
    • Graham DY, Helicobacter pylori infection in the pathogenesis of duodenal ulcer and gastric cancer: a model. Gastroenterology 1997;113:1983-91.
    • (1997) Gastroenterology , vol.113 , pp. 1983-1991
    • Graham, D.Y.1
  • 49
    • 0029901047 scopus 로고    scopus 로고
    • Dietary salt, nitrate and stomach cancer mortality in 24 countries
    • Joosens JV, Hill MJ, Elliott P, et al. Dietary salt, nitrate and stomach cancer mortality in 24 countries. Int J Epidemiol 1996;25:494-504.
    • (1996) Int J Epidemiol , vol.25 , pp. 494-504
    • Joosens, J.V.1    Hill, M.J.2    Elliott, P.3
  • 51
    • 0036305789 scopus 로고    scopus 로고
    • Chinese tea consumption and lower risk of Helicobacter infection
    • Yee YK, Koo MW, Szeto ML. Chinese tea consumption and lower risk of Helicobacter infection. J Gastroenterol Hepatol 2002;17:552-5.
    • (2002) J Gastroenterol Hepatol , vol.17 , pp. 552-555
    • Yee, Y.K.1    Koo, M.W.2    Szeto, M.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.