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Volumn 14, Issue 14, 2006, Pages 4718-4730
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Design, synthesis, and biological activity of N6-substituted-4′-thioadenosines at the human A3 adenosine receptor
a
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Author keywords
Antagonist; G protein coupled receptor; Nucleoside; Partial agonist; Purines; Radioligand binding
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Indexed keywords
2,6 CHLORO 9 (4 THIO BETA DELTA RIBOFURANOSYL)PURINE;
2,6 DICHLORO 9 [2,3 O ISOPROPYLIDENE) 4 THIO BETA DELTA RIBOFURANOSYL]PURINE;
4' THIOADENOSINE DERIVATIVE;
6 (1 NAPHTHYLMETHYL)AMINO 9 (4 THIO BETA DELTA RIBOFURANOSYL)PURINE;
6 (1,2 DIPHENYLETHYL)AMINO 9 (4 THIO BETA DELTA RIBOFURANOSYL)PURINE;
6 (2 PHENYL CYCLOPROPYL)AMINO 9 (4 THIO BETA DELTA RIBOFURANOSYL)PURINE;
6 (3 CHLOROBENZYL)AMINO 9 (4 THIO BETA DELTA RIBOFURANOSYL)PURINE;
6 (3 FLUOROBENZYL)AMINO 9 (4 THIO BETA DELTA RIBOFURANOSYL)PURINE;
6 (3 FLUOROPHENETHYL)AMINO 9 (4 THIO BETA DELTA RIBOFURANOSYL)PURINE;
6 (3 IODOBENZYL)AMINO 9 (4 THIO BETA DELTA RIBOFURANOSYL)PURINE;
6 (3 METHYLBENZYL)AMINO 9 (4 THIO BETA DELTA RIBOFURANOSYL)PURINE;
6 (3 METHYLBUTYL)AMINO 9 (4 THIO BETA DELTA RIBOFURANOSYL)PURINE;
6 (3 TRIFLUOROMETHYLBENZYL)AMINO 9 (4 THIO BETA DELTA RIBOFURANOSYL)PURINE;
6 (3,3 DIPHENYLPROPYL)AMINO 9 (4 THIO BETA DELTA RIBOFURANOSYL)PURINE;
6 (CYCLOPROPYLMETHYL)AMINO 9 (4 THIO BETA DELTA RIBOFURANOSYL)PURINE;
6 (PIPERIDIN 1 YL)AMINO 9 (4 THIO BETA DELTA RIBOFURANOSYL)PURINE;
6 AMINO 9 (4 THIO BETA DELTA RIBOFURANOSYL)PURINE;
6 BENZYLAMINO 9 (4 THIO BETA DELTA RIBOFURANOSYL)PURINE;
6 CHLORO 9 (4 THIO BETA DELTA RIBOFURANOSYL)PURINE;
6 CHLORO 9 [2,3 O ISOPROPYLIDENE) 4 THIO BETA DELTA RIBOFURANOSYL]PURINE;
6 CHLORO 9 [5 O BENZOYL 2,3 O ISOPROPYLIDENE) 4 THIO BETA DELTA RIBOFURANOSYL]PURINE;
6 CYCLOBUTYLAMINO 9 (4 THIO BETA DELTA RIBOFURANOSYL)PURINE;
6 CYCLOPROPYLAMINO 9 (4 THIO BETA DELTA RIBOFURANOSYL)PURINE;
6 DICHLORO 9 [5 O BENZOYL 2,3 O ISOPROPYLIDENE) 4 THIO BETA DELTA RIBOFURANOSYL]PURINE;
6 METHYLAMINO 9 (4 THIO BETA DELTA RIBOFURANOSYL)PURINE;
6 PHENETHYLAMINO 9 (4 THIO BETA DELTA RIBOFURANOSYL)PURINE;
ADENOSINE A3 RECEPTOR;
ADENOSINE DERIVATIVE;
GAMMA LACTONE DERIVATIVE;
UNCLASSIFIED DRUG;
UNINDEXED DRUG;
ARTICLE;
BIOLOGICAL ACTIVITY;
DRUG DESIGN;
DRUG POTENCY;
DRUG SYNTHESIS;
STRUCTURE ACTIVITY RELATION;
ADENOSINE;
ANIMALS;
CHO CELLS;
CRICETINAE;
CYCLIC AMP;
DRUG DESIGN;
HUMANS;
KINETICS;
LIGANDS;
MAGNETIC RESONANCE SPECTROSCOPY;
RECEPTOR, ADENOSINE A1;
RECEPTOR, ADENOSINE A2A;
RECEPTOR, ADENOSINE A3;
RECOMBINANT PROTEINS;
STRUCTURE-ACTIVITY RELATIONSHIP;
THIONUCLEOSIDES;
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EID: 33646865696
PISSN: 09680896
EISSN: None
Source Type: Journal
DOI: 10.1016/j.bmc.2006.03.030 Document Type: Article |
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Times cited : (23)
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References (24)
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