Murine leukemia virus vector integration favors promoter regions and regional hot spots in a human T-cell line

Biochemical and Biophysical Research Communications

Volumn 345, Issue 3, 2006, Pages 1099-1107

  Tsukahara, Tomonori ^a   Agawa, Hideyuki ^a   Matsumoto, Sayori ^a   Matsuda, Mizuho ^a   Ueno, Shuichi ^a   Yamashita, Yuki ^a   Yamada, Koichiro ^a   Tanaka, Nobuyuki ^b   Kojima, Katsuhiko ^a   Takeshita, Toshikazu ^a  

^a SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Gene therapy; Insertional mutagenesis; Leukemia; MLV vector; Oncogenes; T cells; X SCID

Indexed keywords

MESSENGER RNA; VIRUS VECTOR;

ARTICLE; CELL CLONE; CELL LINE; CONTROLLED STUDY; CPG ISLAND; GENE SEQUENCE; GENE TARGETING; GENE TRANSFER; HELA CELL; HUMAN; HUMAN CELL; INTRON; MURINE LEUKEMIA VIRUS; MURINE LEUKEMIA VIRUS VECTOR; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTO ONCOGENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; T LYMPHOCYTE; TRANSCRIPTION REGULATION; VIRAL GENE THERAPY; VIRUS DNA CELL DNA INTERACTION;

CELL LINE; CLONING, MOLECULAR; CPG ISLANDS; GENE THERAPY; GENETIC VECTORS; HUMANS; LEUKEMIA VIRUS, MURINE; MUTAGENESIS; PROMOTER REGIONS (GENETICS); REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; T-LYMPHOCYTES; TRANSCRIPTION INITIATION SITE; VIRUS INTEGRATION;

MURINE LEUKEMIA VIRUS;

EID: 33646826974     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2006.05.007     Document Type: Article

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