A review of the interaction of Bacillus anthracis with cells of the innate immune response

Berliner und Munchener Tierarztliche Wochenschrift

Volumn 119, Issue 5-6, 2006, Pages 216-221

  Mayer Scholl, Anne ^a  

^a MAX PLANCK INSTITUTE FOR INFECTION BIOLOGY   (Germany)

Author keywords

Anthrax; B. anthracis; Dendritic cells; Innate immunity; Macrophages; Neutrophils

Indexed keywords

ALPHA DEFENSIN; CYTOKINE;

ANIMAL; ANTHRAX; BACILLUS ANTHRACIS; DENDRITIC CELL; HUMAN; IMMUNOLOGY; INNATE IMMUNITY; MACROPHAGE; MICROBIOLOGY; MOUSE; NEUTROPHIL; PATHOGENICITY; REVIEW;

ALPHA-DEFENSINS; ANIMALS; ANTHRAX; BACILLUS ANTHRACIS; CYTOKINES; DENDRITIC CELLS; HUMANS; IMMUNITY, NATURAL; MACROPHAGES; MICE; NEUTROPHILS;

BACILLUS ANTHRACIS; BACTERIA (MICROORGANISMS);

EID: 33646788458     PISSN: 00059366     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (71)

1. Abramova, F. A., L. M. Grinberg, O. V. Yampolskaya, D. H. Walker (1993): Pathology of inhalational anthrax in 42 cases from the Sverdlovsk outbreak of 1979. Proc. Natl. Acad. Sci. U S A. 90, 2291-2294.
2. Agrawal, A., J. Lingappa, S. H. Leppla, S. Agrawal, A. Jabbar, C. Quinn, B. Pulendran (2003): Impairment of dendritic cells and adaptive immunity by anthrax lethal toxin. Nature 424, 329-334.
3. th edn. Whitehouse Station: Merck + Co, Inc, 432-435.
4. Albrink, W. S., S. M. Brooks, R. E. Biron, M. Kopel (1960): Human inhalation anthrax. A report of three fatal cases. Am. J. Pathol. 36, 147-171.
5. Alexeyev, O. A., V. G. Morozov, T. V. Suzdaltseva, A. S. Mishukov, L. A. Steinberg (1994): Impaired neutrophil function in the cutaneous form of anthrax. Infection 22, 281-282.
6. Alileche, A., E. R. Serfass, S. M. Muehlbauer, S. A. Porcelli, J. Brojatsch (2005): Anthrax lethal toxin-mediated killing of human and murine dendritic cells impairs the adaptive immune response. PLoS Pathog. 1, e19.
7. Berdjis, C. C., C. A. Gleiser (1964): Experimental Subcutaneous Anthrax in Chimpanzees. Exp. Mol. Pathol. 33, 63-75.
8. Borregaard, N., J. B. Cowland (1997): Granules of the human neutrophilic polymorphonuclear leukocyte. Blood 89, 3503-3521.
9. Brachman, P. S. (1980): Inhalation anthrax. Ann N Y Acad Sci. 353, 83-93.
10. Bradley, K. A., J. Mogridge, M. Mourez, R. J. Collier, J. A. Young (2001): Identification of the cellular receptor for anthrax toxin. Nature 414, 225-229.
11. Brittingham, K. C., G. Ruthel, R. G. Panchal, C. L. Fuller, W. J. Ribot, T. A. Hoover, H. A. Young, A. O. Anderson, S. Bavari (2005): Dendritic cells endocytose Bacillus anthracis spores: implications for anthrax pathogenesis. J. Immunol. 174, 5545-5552.
12. Cordoba-Rodriguez, R., H. Fang, C. S. Lankford, D. M. Frucht (2004): Anthrax lethal toxin rapidly activates caspase-1/ICE and induces extracellular release of interleukin (IL)-1beta and IL-18. J. Biol. Chem. 279, 20563-20566.
13. Cote, C. K., K. M. Rea, S. L. Norris, N. van Rooijen, S. L. Welkos (2004): The use of a model of in vivo macrophage depletion to study the role of macrophages during infection with Bacillus anthracis spores. Microb. Pathog. 37, 169-175.
14. Cromartie, W. J., W. L. Bloom, D. W. Watson (1947): Studies in infection with Bacillus anthracis. J. Inf. Dis. 80, 1-13.
15. Cui, X., M. Moayeri, Y. Li, X. Li, M. Haley, Y. Fitz, R. Correa-Araujo, S. M. Banks, S. H. Leppla, P. Q. Eichacker (2004): Lethality during continuous anthrax lethal toxin infusion is associated with circulatory shock but not inflammatory cytokine or nitric oxide release in rats. Am. J. Physiol. Regul. Integr. Comp. Physiol. 286, R699-709.
16. Dang, O., L. Navarro, K. Anderson, M. David (2004): Cutting edge: anthrax lethal toxin inhibits activation of IFN-regulatory factor 3 by lipopolysaccharide. J. Immunol. 172, 747-751.
17. Dixon, T. C., A. A. Fadl, T. M. Koehler, J. A. Swanson, P. C. Hanna (2000): Early Bacillus anthracis-macrophage interactions: intracellular survival survival and escape. Cell. Microbiol. 2, 453-463.
18. Dixon, T. C., M. Meselson, J. Guillemin, P. C. Hanna (1999): Anthrax. N. Engl. J. Med. 341, 815-826.
19. Drysdale, M., S. Heninger, J. Hutt, Y. Chen, C. R. Lyons, T. M. Koehler (2005): Capsule synthesis by Bacillus anthracis is required for dissemination in murine inhalation anthrax. Embo J. 24, 221-227.
20. Duesbery, N. S., C. P. Webb, S. H. Leppla, V. M. Gordon, K. R. Klimpel, T. D. Copeland, N. G. Ahn, M. K. Oskarsson, K. Fukasawa, K. D. Paull, G. F. Vande Woude (1998): Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor. Science 280, 734-737.
21. Dutz, W., E. Kohout (1971): Anthrax. Pathol. Annu. 6, 209-248.
22. Erwin, J. L., L. M. DaSilva, S. Bavari, S. F. Little, A. M. Friedlander, T. C. Chanh (2001): Macrophage-derived cell lines do not express proinflammatory cytokines after exposure to Bacillus anthracis lethal toxin. Infect. Immun. 69, 1175-1177.
23. Ezzell, J. W., S. L. Welkos (1999): The capsule of bacillus anthracis, a review. J. Appl. Microbiol. 87, 250.
24. Faurschou, M., N. Borregaard (2003): Neutrophil granules and secretory vesicles in inflammation. Microbes Infect. 5, 1317-1327.
25. Fukao, T. (2004): Immune system paralysis by anthrax lethal toxin: the roles of innate and adaptive immunity. Lancet Infect. Dis. 4, 166-170.
26. Gleiser, C. A., W. S. Gochenour, Jr., M. K. Ward (1968): Pulmonary lesions in dogs and pigs exposed to a cloud of anthrax spores. J. Comp. Pathol. 78, 445-448.
27. Gold, J. A., Y. Hoshino, S. Hoshino, M. B. Jones, A. Nolan, M. D. Weiden (2004): Exogenous gamma and alpha/beta interferon rescues human macrophages from cell death induced by Bacillus anthracis. Infect. Immun. 72, 1291-1297.
28. Guidi-Rontani, C. (2002): The alveolar macrophage: the Trojan horse of Bacillus anthracis. Trends Microbiol. 10, 405-409.
29. Guidi-Rontani, C., M. Mock (2002): Macrophage interactions. Curr. Top. Microbiol. Immunol. 271, 115-141.
30. Guidi-Rontani, C., M. Weber-Levy, E. Labruyere, M. Mock (1999): Germination of Bacillus anthracis spores within alveolar macrophages. Mol. Microbiol. 31, 9-17.
31. Hampton, M. B., A. J. Kettle, C. C. Winterbourn (1998): Inside the neutrophil phagosome: oxidants, myeloperoxidase, and bacterial killing. Blood 92, 3007-3017.
32. Hanna, P. C., D. Acosta, R. J. Collier (1993): On the role of macrophages in anthrax. Proc. Natl. Acad. Sci. U S A 90, 10198-10201.
33. Hanna, P. C., B. A. Kruskal, R. A. Ezekowitz, B. R. Bloom, R. J. Collier (1994): Role of macrophage oxidative burst in the action of anthrax lethal toxin. Mol. Med. 1, 7-18.
34. Hugh-Jones, M. E., V. de Vos (2002): Anthrax and wildlife. Rev. Sci. Tech. 21, 359-383.
35. Kagan, B. L., M. E. Selsted, T. Ganz, R. I. Lehrer (1990): Antimicrobial defensin peptides form voltage-dependent ion-permeable channels in planar lipid bilayer membranes. Proc. Natl. Acad. Sci. U S A 87, 210-214.
36. Kang, T. J., M. J. Fenton, M. A. Weiner, S. Hibbs, S. Basu, L. Baillie, A. S. Cross (2005): Murine macrophages kill the vegetative form of Bacillus anthracis. Infect. Immun. 73, 7495-7501.
37. Keppie, J., P. W. Harris-Smith, H. Smith (1963): The Chemical Basis of the Virulence of Bacillus Anthracis. Ix. Its Aggressins and Their Mode of Action. Br. J. Exp. Pathol. 44, 446-453.
38. Kim, C., N. Gajendran, H. W. Mittrucker, M. Weiwad, Y. H. Song, R. Hurwitz, M. Wilmanns, G. Fischer, S. H. Kaufmann (2005): Human alpha-defensins neutralize anthrax lethal toxin and protect against its fatal consequences. Proc. Natl. Acad. Sci. U S A 102, 4830-1835.
39. Kim, S. O., Q. Jing, K. Hoebe, B. Beutler, N. S. Duesbery, J. Han (2003): Sensitizing anthrax lethal toxin-resistant macrophages to lethal toxin-induced killing by tumor necrosis factor-alpha. J. Biol. Chem. 278, 7413-7421.
40. Kirby, J. E. (2004): Anthrax lethal toxin induces human endothelial cell apoptosis. Infect. Immun. 72, 430-439.
41. Lebowich, R. J., B. G. McKillip, J. R. Conboy (1943): Cutaneous Anthrax: a pathological study with clinical correlation. Am. J. Clin. Pathol. 13, 505-515.
42. Lee, W. L., R. E. Harrison, S. Grinstein (2003): Phagocytosis by neutrophils. Microbes Infect. 5, 1299-1306.
43. Leppla, S. H. (1982): Anthrax toxin edema factor: a bacterial adenylate cyclase that increases cyclic AMP concentrations of eukaryotic cells. Proc. Natl. Acad. Sci. U S A 79, 3162-3166.
44. Lin, C. G., Y. T. Kao, W. T. Liu, H. H. Huang, K. C. Chen, T. M. Wang, H. C. Lin (1996): Cytotoxic effects of anthrax lethal toxin on macrophage-like cell line J774A.1. Curr. Microbiol. 33, 224-227.
45. Makino, S., M. Watarai, H. I. Cheun, T. Shirahata, I. Uchida (2002): Effect of the lower molecular capsule released from the cell surface of Bacillus anthracis on the pathogenesis of anthrax. J. Infect. Dis. 186, 227-233.
46. Mayer-Scholl, A., R. Hurwitz, V. Brinkmann, M. Schmid, P. Jungblut, Y. Weinrauch, A. Zychlinsky (2005): Human neutrophils kill Bacillus anthracis. PLoS Pathog. 1, e23.
47. Meselson, M., J. Guillemin, M. Hugh-Jones, A. Langmuir, I. Popova, A. Shelokov, O. Yampolskaya (1994): The Sverdlovsk anthrax outbreak of 1979. Science 266, 1202-1208.
48. Moayeri, M., D. Haines, H. A. Young, S. H. Leppla (2003): Bacillus anthracis lethal toxin induces TNF-alpha-independent hypoxia-mediated toxicity in mice. J. Clin. Invest. 112, 670-682.
49. Mock, M., A. Fouet (2001): Anthrax. Annu. Rev. Microbiol. 55, 647-671.
50. O'Brien, J., A. Friedlander, T. Dreier, J. Ezzell, S. Leppla (1985): Effects of anthrax toxin components on human neutrophils. Infect. Immun. 47, 306-310.
51. Park, J. M., F. R. Greten, Z. W. Li, M. Karin (2002): Macrophage apoptosis by anthrax lethal factor through p38 MAP kinase inhibition. Science 297, 2048-2051.
52. Pellizzari, R., C. Guidi-Rontani, G. Vitale, M. Mock, C. Montecucco (1999): Anthrax lethal factor cleaves MKK3 in macrophages and inhibits the LPS/IFNgamma-induced release of NO and TNFalpha. FEBS Lett. 462, 199-204.
53. Pellizzari, R., C. Guidi-Rontani, G. Vitale, M. Mock, C. Montecucco (2000): Lethal factor of Bacillus anthracis cleaves the N-terminus of MAPKKs: analysis of the intracellular consequences in macrophages. Int. J. Med. Microbiol. 290, 421-427.
54. Pickering, A. K., T. J. Merkel (2004): Macrophages release tumor necrosis factor alpha and interleukin-12 in response to intracellular Bacillus anthracis spores. Infect. Immun. 72, 3069-3072.
55. Pickering, A. K., M. Osorio, G. M. Lee, V. K. Grippe, M. Bray, T. J. Merkel (2004): Cytokine response to infection with Bacillus anthracis spores. Infect. Immun. 72, 6382-6389.
56. Popov, S. G., T. G. Popova, E. Grene, F. Klotz, J. Cardwell, C. Bradburne, Y. Jama, M. Maland, J. Wells, A. Nalca, T. Voss, C. Bailey, K. Alibek (2004): Systemic cytokine response in murine anthrax. Cell. Microbiol. 6, 225-233.
57. Rescigno, M. (2002): Dendritic cells and the complexity of microbial infection. Trends Microbiol. 10, 425-461.
58. Roos, D., R. van Bruggen, C. Meischl (2003): Oxidative killing of microbes by neutrophils. Microbes Infect. 5, 1307-1315.
59. Roos, D., C. C. Winterbourn (2002): Immunology. Lethal weapons. Science 296, 669-671.
60. Scobie, H. M., G. J. Rainey, K. A. Bradley, J. A. Young (2003): Human capillary morphogenesis protein 2 functions as an anthrax toxin receptor. Proc. Natl. Acad. Sci. U S A 100, 5170-5174.
61. Swartz, M. N. (2001): Recognition and management of anthrax - an update. N. Engl. J. Med. 345, 1621-1626.
62. Tournier, J. N., A. Quesnel-Hellmann, J. Mathieu, C. Montecucco, W. J. Tang, M. Mock, D. R. Vidal, P. L. Goossens (2005): Anthrax edema toxin cooperates with lethal toxin to impair cytokine secretion during infection of dendritic cells. J. Immunol. 174, 4934-4941.
63. Vitale, G., L. Bernardi, G. Napolitani, M. Mock, C. Montecucco (2000): Susceptibility of mitogen-activated protein kinase kinase family members to proteolysis by anthrax lethal factor. Biochem. J. 352 Pt 3, 739-745.
64. Vitale, G., R. Pellizzari, C. Recchi, G. Napolitani, M. Mock, C. Montecucco (1999): Anthrax lethal factor cleaves the N-terminus of MAPKKS and induces tyrosine/threonine phosphorylation of MAPKS in cultured macrophages. J. Appl. Microbiol. 87, 288.
65. Watters, J. W., K. Dewar, J. Lehoczky, V. Boyartchuk, W. F. Dietrich (2001): Kif1C, a kinesin-like motor protein, mediates mouse macrophage resistance to anthrax lethal factor. Curr. Biol. 11, 1503-1511.
66. Welkos, S., A. Friedlander, S. Weeks, S. Little, I. Mendelson (2002): In-vitro characterisation of the phagocytosis and fate of anthrax spores in macrophages and the effects of anti-PA antibody. J. Med. Microbiol. 51, 821-831.
67. Welkos, S. L. (1991): Plasmid-associated virulence factors of non-toxigenic (pX01-) Bacillus anthracis. Microb. Pathog. 10, 183-198.
68. Welkos, S. L., R. W. Trotter, D. M. Becker, G. O. Nelson (1989): Resistance to the Sterne strain of B. anthracis: phagocytic cell responses of resistant and susceptible mice. Microb. Pathog. 7, 15-35.
69. WHO, http://www.who.int/csr/resources/publications/anthrax/WHO_ EMC_ZDI_98_6/en/
70. Wright G. G., G. L. Mandell (1986): Anthrax toxin blocks priming of neutrophils by lipopolysaccharide and by muramyl dipeptide. J. Exp. Med. 164, 1700-1709.
71. Zaucha, G. M., L. M. Pitt, J. Estep, B. E. Ivins, A. M. Friedlander (1998): The pathology of experimental anthrax in rabbits exposed by inhalation and subcutaneous inoculation. Arch. Pathol. Lab. Med. 122, 982-992.