-
1
-
-
29844433234
-
Overview of molecular relationships in the voltage-gated ion channel superfamily
-
Yu, F. H.; Yarov-Yarovoy, V.; Gutman, G. A.; Catterall, W. A. Overview of molecular relationships in the voltage-gated ion channel superfamily. Pharmacol. Rev. 2005, 57, 387-395.
-
(2005)
Pharmacol. Rev.
, vol.57
, pp. 387-395
-
-
Yu, F.H.1
Yarov-Yarovoy, V.2
Gutman, G.A.3
Catterall, W.A.4
-
2
-
-
0242657337
-
Potassium channels
-
MacKinnon, R. Potassium channels. FEBS Lett. 2003, 555, 62-65.
-
(2003)
FEBS Lett.
, vol.555
, pp. 62-65
-
-
MacKinnon, R.1
-
3
-
-
29844437655
-
LIII. Nomenclature and molecular relationships of voltage-gated potassium channels
-
International Union of Pharmacology
-
Gutman, G. A.; Chandy, K. G.; Grissmer, S.; Lazdunski, M.; McKinnon, D.; Pardo, L. A.; Robertson, G. A.; Rudy, B.; Sanguinetti, M. C.; Stuhmer, W.; Wang, X. International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels. Pharmacol. Rev. 2005, 57, 473-508.
-
(2005)
Pharmacol. Rev.
, vol.57
, pp. 473-508
-
-
Gutman, G.A.1
Chandy, K.G.2
Grissmer, S.3
Lazdunski, M.4
McKinnon, D.5
Pardo, L.A.6
Robertson, G.A.7
Rudy, B.8
Sanguinetti, M.C.9
Stuhmer, W.10
Wang, X.11
-
4
-
-
29844438166
-
XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels
-
International Union of Pharmacology
-
Catterall, W. A.; Goldin, A. L.; Waxman, S. G. International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels. Pharmacol. Rev. 2005, 57, 397-409.
-
(2005)
Pharmacol. Rev.
, vol.57
, pp. 397-409
-
-
Catterall, W.A.1
Goldin, A.L.2
Waxman, S.G.3
-
5
-
-
29844439240
-
XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels
-
International Union of Pharmacology
-
Catterall, W. A.; Perez-Reyes, E.; Snutch, T. P.; Striessnig, J. International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels. Pharmacol. Rev. 2005, 57, 411-425.
-
(2005)
Pharmacol. Rev.
, vol.57
, pp. 411-425
-
-
Catterall, W.A.1
Perez-Reyes, E.2
Snutch, T.P.3
Striessnig, J.4
-
6
-
-
0032478818
-
+ conduction and selectivity
-
+ conduction and selectivity. Science 1998, 280, 69-77.
-
(1998)
Science
, vol.280
, pp. 69-77
-
-
Doyle, D.A.1
Morais Cabral, J.2
Pfuetzner, R.A.3
Kuo, A.4
Gulbis, J.M.5
Cohen, S.L.6
Chait, B.T.7
MacKinnon, R.8
-
7
-
-
0027497515
-
Molecular evolution of voltage-sensitive ion channel genes: On the origins of electrical excitability
-
Strong, M.; Chandy, K. G.; Gutman, G. A. Molecular evolution of voltage-sensitive ion channel genes: on the origins of electrical excitability. Mol. Biol. Evol. 1993, 10, 221-242.
-
(1993)
Mol. Biol. Evol.
, vol.10
, pp. 221-242
-
-
Strong, M.1
Chandy, K.G.2
Gutman, G.A.3
-
9
-
-
30444434227
-
A short history of voltage-gated calcium channels
-
Dolphin, A. C. A short history of voltage-gated calcium channels. Br. J. Pharmacol. 2006, 147, S56-S62.
-
(2006)
Br. J. Pharmacol.
, vol.147
-
-
Dolphin, A.C.1
-
11
-
-
0345185172
-
Beta subunits of voltage-gated calcium channels
-
Dolphin, A. C. Beta subunits of voltage-gated calcium channels. J. Bioenerg. Biomembr. 2003, 35, 599-620.
-
(2003)
J. Bioenerg. Biomembr.
, vol.35
, pp. 599-620
-
-
Dolphin, A.C.1
-
12
-
-
0037022783
-
Structure and function of voltage-dependent ion channel regulatory beta subunits
-
Hanlon, M. R.; Wallace, B. A. Structure and function of voltage-dependent ion channel regulatory beta subunits. Biochemistry 2002, 41, 2886-2894.
-
(2002)
Biochemistry
, vol.41
, pp. 2886-2894
-
-
Hanlon, M.R.1
Wallace, B.A.2
-
14
-
-
0031698217
-
Structures and functions of calcium channel β subunits
-
Birnbaumer, L.; Qin, N.; Olcese, R.; Tareilus, E.; Platano, D.; Costantin, J.; Stefani, E. Structures and functions of calcium channel β subunits. J. Bioenerg. Biomembr. 1998, 30, 357-375.
-
(1998)
J. Bioenerg. Biomembr.
, vol.30
, pp. 357-375
-
-
Birnbaumer, L.1
Qin, N.2
Olcese, R.3
Tareilus, E.4
Platano, D.5
Costantin, J.6
Stefani, E.7
-
15
-
-
9444251020
-
Hypotensive agents from snake venoms
-
Joseph, R.; Pahari, S.; Hodgson, W. C.; Kini, R. M. Hypotensive agents from snake venoms. Curr. Drug Targets Cardiovasc. Haematol. Disord. 2004, 4, 437-459.
-
(2004)
Curr. Drug Targets Cardiovasc. Haematol. Disord.
, vol.4
, pp. 437-459
-
-
Joseph, R.1
Pahari, S.2
Hodgson, W.C.3
Kini, R.M.4
-
16
-
-
0018900234
-
The potent excitatory effect of a novel polypeptide, anthopleurin-B, isolated from a sea anemone (Anthopleura xanthogrammica) on the frog spinal cord
-
Kudo, Y.; Shibata, S. The potent excitatory effect of a novel polypeptide, anthopleurin-B, isolated from a sea anemone (Anthopleura xanthogrammica) on the frog spinal cord. J. Pharmacol. Exp. Ther. 1980, 214, 443-448.
-
(1980)
J. Pharmacol. Exp. Ther.
, vol.214
, pp. 443-448
-
-
Kudo, Y.1
Shibata, S.2
-
17
-
-
9144242506
-
Sodium channel toxins - Receptor targeting and therapeutic potential
-
French, R. J.; Terlau, H. Sodium channel toxins - receptor targeting and therapeutic potential. Curr. Med. Chem. 2004, 11, 3053-3064.
-
(2004)
Curr. Med. Chem.
, vol.11
, pp. 3053-3064
-
-
French, R.J.1
Terlau, H.2
-
18
-
-
0347989461
-
Conus venoms: A rich source of novel ion channel-targeted peptides
-
Terlau, H.; Olivera, B. M. Conus venoms: a rich source of novel ion channel-targeted peptides. Physiol. Rev. 2004, 84, 41-68.
-
(2004)
Physiol. Rev.
, vol.84
, pp. 41-68
-
-
Terlau, H.1
Olivera, B.M.2
-
19
-
-
33646804559
-
Conotoxins: Therapeutic potential and application
-
Layer, R.T.; McIntosh, J.M. Conotoxins: therapeutic potential and application. Mar. Drugs 2006, 4, 82-118.
-
(2006)
Mar. Drugs
, vol.4
, pp. 82-118
-
-
Layer, R.T.1
McIntosh, J.M.2
-
20
-
-
33144485759
-
Peptide Toxins in Sea Anemones: Structural and Functional Aspects
-
Honma, T.; Shiomi, K. Peptide Toxins in Sea Anemones: Structural and Functional Aspects. Mar. Biotechnol. 2006, 8, 1-10.
-
(2006)
Mar. Biotechnol.
, vol.8
, pp. 1-10
-
-
Honma, T.1
Shiomi, K.2
-
21
-
-
17144385848
-
Evolutionary diversification of TTX-resistant sodium channels in a predator-prey interaction
-
Geffeney, S. L.; Fujimoto, E.; Brodie, E. D. 3rd; Brodie, E. D.; Ruben, P. C. Evolutionary diversification of TTX-resistant sodium channels in a predator-prey interaction. Nature 2005, 434, 759-763.
-
(2005)
Nature
, vol.434
, pp. 759-763
-
-
Geffeney, S.L.1
Fujimoto, E.2
Brodie III, E.D.3
Brodie, E.D.4
Ruben, P.C.5
-
22
-
-
33646806510
-
New conotoxin SO-3 targeting N-type voltage-sensitive calcium channels
-
Wen, L.; Yang, S.; Zhou, W.; Zhang, Y.; Huang, P. New conotoxin SO-3 targeting N-type voltage-sensitive calcium channels. Mar. Drugs 2006, 4, 215-227.
-
(2006)
Mar. Drugs
, vol.4
, pp. 215-227
-
-
Wen, L.1
Yang, S.2
Zhou, W.3
Zhang, Y.4
Huang, P.5
-
23
-
-
26444555081
-
Tropical marine neurotoxins: Venoms to drugs
-
Watters, M. R. Tropical marine neurotoxins: venoms to drugs. Semin. Neurol. 2005, 25, 278-289.
-
(2005)
Semin. Neurol.
, vol.25
, pp. 278-289
-
-
Watters, M.R.1
-
24
-
-
0002866731
-
Sea anemone polypeptide toxins affecting sodium channels: Initial structure-activity investigations
-
Hall, S. and Strichartz, G., Editor. Washington, D.C.: American Chemical Society
-
Kem, W. R.; Pennington, M. W.; Dunn, B. M. Sea anemone polypeptide toxins affecting sodium channels: Initial structure-activity investigations. Hall, S. and Strichartz, G., Editor. Marine Toxins: Origin, Structure, and Molecular Pharmacology. Washington, D.C.: American Chemical Society; 1990; pp. 279-289.
-
(1990)
Marine Toxins: Origin, Structure, and Molecular Pharmacology
, pp. 279-289
-
-
Kem, W.R.1
Pennington, M.W.2
Dunn, B.M.3
-
25
-
-
0025915724
-
Structure and structure-function relationships of sea anemone proteins that interact with the sodium channel
-
Norton, R. S. Structure and structure-function relationships of sea anemone proteins that interact with the sodium channel. Toxicon 1991, 29, 1051-1084.
-
(1991)
Toxicon
, vol.29
, pp. 1051-1084
-
-
Norton, R.S.1
-
26
-
-
33646764233
-
Marine toxins that target voltage-gated sodium channels
-
Ahmed, A-S.; McArthur, J.; Ostroumov, V.; French, R.J. Marine toxins that target voltage-gated sodium channels. Mar. Drugs 2006, 4, 157-192.
-
(2006)
Mar. Drugs
, vol.4
, pp. 157-192
-
-
Ahmed, A.-S.1
McArthur, J.2
Ostroumov, V.3
French, R.J.4
-
27
-
-
0017103673
-
Amino-acid sequence of a coelenterate toxin: Toxin II from Anemonia sulcata
-
Wunderer, G.; Fritz, H.; Wachter, E.; Machleidt, W. Amino-acid sequence of a coelenterate toxin: toxin II from Anemonia sulcata. Eur. J. Biochem. 1976, 68, 193-198.
-
(1976)
Eur. J. Biochem.
, vol.68
, pp. 193-198
-
-
Wunderer, G.1
Fritz, H.2
Wachter, E.3
Machleidt, W.4
-
28
-
-
0017617014
-
Amino acid sequence of the Anthopleura xanthogrammica heart stimulant, anthopleurin A
-
Tanaka, M.; Hainu, M.; Yasunobu, K. T.; Norton, T. R. Amino acid sequence of the Anthopleura xanthogrammica heart stimulant, anthopleurin A. Biochemistry 1977, 16, 204-208.
-
(1977)
Biochemistry
, vol.16
, pp. 204-208
-
-
Tanaka, M.1
Hainu, M.2
Yasunobu, K.T.3
Norton, T.R.4
-
29
-
-
0022345864
-
Amino acid sequence of the Anthopleura xanthogrammica heart stimulant, anthopleurin-B
-
Reimer, N. S.; Yasunobu, C. L.; Yasunobu, K. T.; Norton, T. R. Amino acid sequence of the Anthopleura xanthogrammica heart stimulant, anthopleurin-B. J. Biol. Chem. 1985, 260, 8690-8693.
-
(1985)
J. Biol. Chem.
, vol.260
, pp. 8690-8693
-
-
Reimer, N.S.1
Yasunobu, C.L.2
Yasunobu, K.T.3
Norton, T.R.4
-
30
-
-
19944386547
-
Primary structure, behavioral and electroencephalographic effects of an epileptogenic peptide from the sea anemone Bunodosoma cangicum
-
Cunha, R. B.; Santana, A. N.; Amaral, P. C.; Carvalho, M. D.; Carvalho, D. M.; Cavalheiro, E. A.; Maigret, B.; Ricart, C. A.; Cardi, B. A.; Sousa, M. V.; Carvalho, K. M. Primary structure, behavioral and electroencephalographic effects of an epileptogenic peptide from the sea anemone Bunodosoma cangicum. Toxicon 2005, 45, 207-217.
-
(2005)
Toxicon
, vol.45
, pp. 207-217
-
-
Cunha, R.B.1
Santana, A.N.2
Amaral, P.C.3
Carvalho, M.D.4
Carvalho, D.M.5
Cavalheiro, E.A.6
Maigret, B.7
Ricart, C.A.8
Cardi, B.A.9
Sousa, M.V.10
Carvalho, K.M.11
-
31
-
-
0024535465
-
Calitoxin, a neurotoxic peptide from the sea anemone Calliactis parasitica: Amino acid sequence and electrophysiological properties
-
Cariello, L.; de Santis, A.; Fiore, F.; Piccoli, R.; Spagnuolo, A.; Zanetti, L.; Parente, A. Calitoxin, a neurotoxic peptide from the sea anemone Calliactis parasitica: amino acid sequence and electrophysiological properties. Biochemistry 1989, 28, 2484-2489.
-
(1989)
Biochemistry
, vol.28
, pp. 2484-2489
-
-
Cariello, L.1
De Santis, A.2
Fiore, F.3
Piccoli, R.4
Spagnuolo, A.5
Zanetti, L.6
Parente, A.7
-
32
-
-
0028330246
-
Isolation and characterization of two genes encoding calitoxins, neurotoxic peptides from Calliactis parasitica (Cnidaria)
-
Spagnuolo, A.; Zanetti, L.; Cariello, L.; Piccoli, R. Isolation and characterization of two genes encoding calitoxins, neurotoxic peptides from Calliactis parasitica (Cnidaria). Gene 1994, 138, 187-191.
-
(1994)
Gene
, vol.138
, pp. 187-191
-
-
Spagnuolo, A.1
Zanetti, L.2
Cariello, L.3
Piccoli, R.4
-
33
-
-
0037305692
-
An epidermal growth factor-like toxin and two sodium channel toxins from the sea anemone Stichodactyla gigantea
-
Shiomi, K.; Honma, T.; Ide, M.; Nagashima, Y.; Ishida, M.; Chino, M. An epidermal growth factor-like toxin and two sodium channel toxins from the sea anemone Stichodactyla gigantea. Toxicon 2003, 41, 229-236.
-
(2003)
Toxicon
, vol.41
, pp. 229-236
-
-
Shiomi, K.1
Honma, T.2
Ide, M.3
Nagashima, Y.4
Ishida, M.5
Chino, M.6
-
34
-
-
0017172276
-
Isolation and characterization of the cardiotonic polypeptide anthopleurin-A from the sea anemone Anthopleura xanthogrammica
-
Norton, T. R.; Shibata, S.; Kashiwagi, M.; Bentley, J. Isolation and characterization of the cardiotonic polypeptide anthopleurin-A from the sea anemone Anthopleura xanthogrammica. J. Pharm. Sci. 1976, 65, 1368-1374.
-
(1976)
J. Pharm. Sci.
, vol.65
, pp. 1368-1374
-
-
Norton, T.R.1
Shibata, S.2
Kashiwagi, M.3
Bentley, J.4
-
35
-
-
0016424832
-
Isolation and characterisation of three polypeptides with neurotoxic activity from Anemonia sulcata
-
Beress, L.; Beress, R.; Wunderer, G. Isolation and characterisation of three polypeptides with neurotoxic activity from Anemonia sulcata. FEBS Lett. 1975, 50, 311-314.
-
(1975)
FEBS Lett.
, vol.50
, pp. 311-314
-
-
Beress, L.1
Beress, R.2
Wunderer, G.3
-
36
-
-
49549134070
-
Decreased rate of sodium conductance inactivation in the node of Ranvier induced by a polypeptide toxin from sea anemone
-
Bergman, C.; Dubois, J. M.; Rojas, E.; Rathmayer, W. Decreased rate of sodium conductance inactivation in the node of Ranvier induced by a polypeptide toxin from sea anemone. Biochim. Biophys. Acta 1976, 455, 173-184.
-
(1976)
Biochim. Biophys. Acta
, vol.455
, pp. 173-184
-
-
Bergman, C.1
Dubois, J.M.2
Rojas, E.3
Rathmayer, W.4
-
37
-
-
0018135405
-
Sea anemone toxin and scorpion toxin share a common receptor site associated with the action potential sodium ionophore
-
Catterall, W. A.; Beress, L. Sea anemone toxin and scorpion toxin share a common receptor site associated with the action potential sodium ionophore. J. Biol. Chem. 1978, 253, 7393-7396.
-
(1978)
J. Biol. Chem.
, vol.253
, pp. 7393-7396
-
-
Catterall, W.A.1
Beress, L.2
-
38
-
-
0018872762
-
Binding of sea anemone toxin to receptor sites associated with gating system of sodium channel in synaptic nerve endings in vitro
-
Vincent, J. P.; Balerna, M.; Barhanin, J.; Fosset, M.; Lazdunski, M. Binding of sea anemone toxin to receptor sites associated with gating system of sodium channel in synaptic nerve endings in vitro. Proc. Natl. Acad. Sci. U.S.A. 1980 77, 1646-1650.
-
(1980)
Proc. Natl. Acad. Sci. U.S.A.
, vol.77
, pp. 1646-1650
-
-
Vincent, J.P.1
Balerna, M.2
Barhanin, J.3
Fosset, M.4
Lazdunski, M.5
-
39
-
-
0019784023
-
Purification and pharmacological properties of eight sea anemone toxins from Anemonia sulcata, Anthopleura xanthogrammica, Stoichactis giganteus, and Actinodendron plumosum
-
Schweitz, H.; Vincent, J. P.; Barhanin, J.; Frelin, C.; Linden, G.; Hugues, M.; Lazdunski, M. Purification and pharmacological properties of eight sea anemone toxins from Anemonia sulcata, Anthopleura xanthogrammica, Stoichactis giganteus, and Actinodendron plumosum. Biochemistry 1981, 20, 5245-5252.
-
(1981)
Biochemistry
, vol.20
, pp. 5245-5252
-
-
Schweitz, H.1
Vincent, J.P.2
Barhanin, J.3
Frelin, C.4
Linden, G.5
Hugues, M.6
Lazdunski, M.7
-
40
-
-
0023908369
-
Binding properties of sea anemone toxins to sodium channels in the crayfish giant axon
-
Warashina, A.; Ogura, T.; Fujita, S. Binding properties of sea anemone toxins to sodium channels in the crayfish giant axon. Comp. Biochem. Physiol. C 1988, 90, 351-359.
-
(1988)
Comp. Biochem. Physiol. C
, vol.90
, pp. 351-359
-
-
Warashina, A.1
Ogura, T.2
Fujita, S.3
-
41
-
-
0033731909
-
Molecular mechanisms of neurotoxin action on voltage-gated sodium channels
-
Cestele, S.; Catterall, W. A. Molecular mechanisms of neurotoxin action on voltage-gated sodium channels. Biochimie 2000, 82, 883-892.
-
(2000)
Biochimie
, vol.82
, pp. 883-892
-
-
Cestele, S.1
Catterall, W.A.2
-
43
-
-
0031972937
-
A specific interaction between the cardiac sodium channel and site-3 toxin anthopleurin B
-
Benzinger, G. R.; Kyle, J. W.; Blumenthal, K. M.; Hanck, D. A. A specific interaction between the cardiac sodium channel and site-3 toxin anthopleurin B. J. Biol. Chem. 1998, 273, 80-84.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 80-84
-
-
Benzinger, G.R.1
Kyle, J.W.2
Blumenthal, K.M.3
Hanck, D.A.4
-
44
-
-
4043067199
-
Binding specificity of sea anemone toxins to Nav 1.1-1.6 sodium channels: Unexpected contributions from differences in the IV/S3-S4 outer loop
-
Oliveira, J. S.; Redaelli, E.; Zaharenko, A. J.; Cassulini, R. R.; Konno, K.; Pimenta, D. C.; Freitas, J. C.; Clare, J. J.; Wanke, E. Binding specificity of sea anemone toxins to Nav 1.1-1.6 sodium channels: unexpected contributions from differences in the IV/S3-S4 outer loop. J. Biol. Chem. 2004, 279, 33323-33335.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 33323-33335
-
-
Oliveira, J.S.1
Redaelli, E.2
Zaharenko, A.J.3
Cassulini, R.R.4
Konno, K.5
Pimenta, D.C.6
Freitas, J.C.7
Clare, J.J.8
Wanke, E.9
-
45
-
-
0024240855
-
Site of covalent attachment of alpha-scorpion toxin derivatives in domain I of the sodium channel alpha subunit
-
Tejedor, F. J.; Catterall, W. A. Site of covalent attachment of alpha-scorpion toxin derivatives in domain I of the sodium channel alpha subunit. Proc. Natl. Acad. Sci. U.S.A. 1988, 85, 8742-8746.
-
(1988)
Proc. Natl. Acad. Sci. U.S.A.
, vol.85
, pp. 8742-8746
-
-
Tejedor, F.J.1
Catterall, W.A.2
-
46
-
-
0024811112
-
Localization of the receptor site for alpha-scorpion toxins by antibody mapping: Implications for sodium channel topology
-
Thomsen, W. J.; Catterall, W. A. Localization of the receptor site for alpha-scorpion toxins by antibody mapping: implications for sodium channel topology. Proc. Natl. Acad. Sci. U.S.A. 1989, 86, 10161-10165.
-
(1989)
Proc. Natl. Acad. Sci. U.S.A.
, vol.86
, pp. 10161-10165
-
-
Thomsen, W.J.1
Catterall, W.A.2
-
47
-
-
15744403398
-
Differential phospholipid binding by site 3 and site 4 toxins. Implications for structural variability between voltage-sensitive sodium channel domains
-
Smith, J. J.; Alphy, S.; Seibert, A. L.; Blumenthal, K. M. Differential phospholipid binding by site 3 and site 4 toxins. Implications for structural variability between voltage-sensitive sodium channel domains. J. Biol. Chem. 2005, 280, 11127-11133.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 11127-11133
-
-
Smith, J.J.1
Alphy, S.2
Seibert, A.L.3
Blumenthal, K.M.4
-
48
-
-
0029645290
-
Solution structure of the cardiostimulant polypeptide anthopleurin-B and comparison with anthopleurin-A
-
Monks, S. A.; Pallaghy, P. K.; Scanlon, M. J.; Norton, R. S. Solution structure of the cardiostimulant polypeptide anthopleurin-B and comparison with anthopleurin-A. Structure 1995, 3, 791-803.
-
(1995)
Structure
, vol.3
, pp. 791-803
-
-
Monks, S.A.1
Pallaghy, P.K.2
Scanlon, M.J.3
Norton, R.S.4
-
49
-
-
0346850582
-
Arg-14 loop of site 3 anemone toxins: Effects of glycine replacement on toxin affinity
-
Seibert, A. L.; Liu, J.; Hanck, D. A.; Blumenthal, K. M. Arg-14 loop of site 3 anemone toxins: effects of glycine replacement on toxin affinity. Biochemistry 2003, 42, 14515-14521.
-
(2003)
Biochemistry
, vol.42
, pp. 14515-14521
-
-
Seibert, A.L.1
Liu, J.2
Hanck, D.A.3
Blumenthal, K.M.4
-
50
-
-
0029035945
-
Multiple cationic residues of anthopleurin B that determine high affinity and channel isoform discrimination
-
Khera, P. K.; Benzinger, G. R.; Lipkind, G.; Drum, C. L.; Hanck, D. A.; Blumenthal, K. M. Multiple cationic residues of anthopleurin B that determine high affinity and channel isoform discrimination. Biochemistry 1995, 34, 8533-8541.
-
(1995)
Biochemistry
, vol.34
, pp. 8533-8541
-
-
Khera, P.K.1
Benzinger, G.R.2
Lipkind, G.3
Drum, C.L.4
Hanck, D.A.5
Blumenthal, K.M.6
-
51
-
-
0028245287
-
Positively charged amino acid residues located similarly in sea anemone and scorpion toxins
-
Loret, E. P.; del Valle, R. M.; Mansuelle, P.; Sampieri, F.; Rochat, H. Positively charged amino acid residues located similarly in sea anemone and scorpion toxins. J. Biol. Chem. 1994, 269, 16785-16788.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 16785-16788
-
-
Loret, E.P.1
Del Valle, R.M.2
Mansuelle, P.3
Sampieri, F.4
Rochat, H.5
-
52
-
-
0024973385
-
Isolation, characterization, and amino acid sequence of a polypeptide neurotoxin occurring in the sea anemone Stichodactyla helianthus
-
Kem, W. R.; Parten, B.; Pennington, M. W.; Price, D. A.; Dunn, B. M. Isolation, characterization, and amino acid sequence of a polypeptide neurotoxin occurring in the sea anemone Stichodactyla helianthus. Biochemistry 1989, 28, 3483-3489.
-
(1989)
Biochemistry
, vol.28
, pp. 3483-3489
-
-
Kem, W.R.1
Parten, B.2
Pennington, M.W.3
Price, D.A.4
Dunn, B.M.5
-
53
-
-
0021814796
-
Purification, sequence, and pharmacological properties of sea anemone toxins from Radianthus paumotensis. A new class of sea anemone toxins acting on the sodium channel
-
Schweitz, H.; Bidard, J. N.; Frelin, C.; Pauron, D.; Vijverberg, H. P.; Mahasneh, D. M.; Lazdunski, M.; Vilbois, F.; Tsugita, A. Purification, sequence, and pharmacological properties of sea anemone toxins from Radianthus paumotensis. A new class of sea anemone toxins acting on the sodium channel. Biochemistry 1985, 24, 3554-3561.
-
(1985)
Biochemistry
, vol.24
, pp. 3554-3561
-
-
Schweitz, H.1
Bidard, J.N.2
Frelin, C.3
Pauron, D.4
Vijverberg, H.P.5
Mahasneh, D.M.6
Lazdunski, M.7
Vilbois, F.8
Tsugita, A.9
-
54
-
-
0023662404
-
The amino acid sequence of toxin RpIII from the sea anemone, Radianthus paumotensis
-
Metrione, R. M.; Schweitz, H.; Walsh, K. A. The amino acid sequence of toxin RpIII from the sea anemone, Radianthus paumotensis. FEBS Lett. 1987, 218, 59-62.
-
(1987)
FEBS Lett.
, vol.218
, pp. 59-62
-
-
Metrione, R.M.1
Schweitz, H.2
Walsh, K.A.3
-
55
-
-
0023820861
-
Amino acid sequence of neurotoxin II from the sea anemone Radianthus macrodactylus
-
Zykova, T. A.; Kozlovskaia, E. P.; Eliakov, G. B. Amino acid sequence of neurotoxin II from the sea anemone Radianthus macrodactylus. Bioorg. Khim. 1988, 14, 878-882.
-
(1988)
Bioorg. Khim.
, vol.14
, pp. 878-882
-
-
Zykova, T.A.1
Kozlovskaia, E.P.2
Eliakov, G.B.3
-
56
-
-
0022098713
-
Amino acid sequence of a sea anemone toxin from Parasicyonis actinostoloides
-
Nishida, S.; Fujita, S.; Warashina, A.; Satake, M.; Tamiya, N. Amino acid sequence of a sea anemone toxin from Parasicyonis actinostoloides. Eur. J. Biochem. 1985, 150, 171-173.
-
(1985)
Eur. J. Biochem.
, vol.150
, pp. 171-173
-
-
Nishida, S.1
Fujita, S.2
Warashina, A.3
Satake, M.4
Tamiya, N.5
-
57
-
-
0017695282
-
Toxin III from Anemonia sulcata: Primary structure
-
Martinez, G.; Kopeyan, C. Toxin III from Anemonia sulcata: primary structure. FEBS Lett. 1977, 84, 247-252.
-
(1977)
FEBS Lett.
, vol.84
, pp. 247-252
-
-
Martinez, G.1
Kopeyan, C.2
-
58
-
-
0029878263
-
Solution structure of ShK toxin, a novel potassium channel inhibitor from a sea anemone
-
Tudor, J. E.; Pallaghy, P. K.; Pennington, M. W.; Norton, R. S. Solution structure of ShK toxin, a novel potassium channel inhibitor from a sea anemone. Nat. Struct. Biol. 1996, 3, 317-320.
-
(1996)
Nat. Struct. Biol.
, vol.3
, pp. 317-320
-
-
Tudor, J.E.1
Pallaghy, P.K.2
Pennington, M.W.3
Norton, R.S.4
-
59
-
-
6544276937
-
On the convergent evolution of animal toxins. Conservation of a diad of functional residues in potassium channel-blocking toxins with unrelated structures
-
Dauplais, M.; Lecoq, A.; Song, J.; Cotton, J.; Jamin, N.; Gilquin, B.; Roumestand, C.; Vita, C.; de Medeiros, C. L.; Rowan, E. G.; Harvey, A. L.; Menez, A. On the convergent evolution of animal toxins. Conservation of a diad of functional residues in potassium channel-blocking toxins with unrelated structures. J. Biol. Chem. 1997, 272, 4302-4309.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 4302-4309
-
-
Dauplais, M.1
Lecoq, A.2
Song, J.3
Cotton, J.4
Jamin, N.5
Gilquin, B.6
Roumestand, C.7
Vita, C.8
De Medeiros, C.L.9
Rowan, E.G.10
Harvey, A.L.11
Menez, A.12
-
60
-
-
3943076416
-
An essential binding surface for ShK toxin interaction with rat brain potassium channels
-
Pennington, M. W.; Mahnir, V. M.; Khaytin, I.; Zaydenberg, I.; Byrnes, M. E.; Kem, W. R. An essential binding surface for ShK toxin interaction with rat brain potassium channels. Biochemistry 1996, 35, 16407-16411.
-
(1996)
Biochemistry
, vol.35
, pp. 16407-16411
-
-
Pennington, M.W.1
Mahnir, V.M.2
Khaytin, I.3
Zaydenberg, I.4
Byrnes, M.E.5
Kem, W.R.6
-
61
-
-
0033544906
-
Mapping the functional anatomy of BgK on Kv1.1, Kv1.2, and Kv1.3. Clues to design analogs with enhanced selectivity
-
Alessandri-Haber, N.; Lecoq, A.; Gasparini, S.; Grangier-Macmath, G.; Jacquet, G.; Harvey, A. L.; de Medeiros, C.; Rowan, E. G.; Gola, M.; Menez, A.; Crest, M. Mapping the functional anatomy of BgK on Kv1.1, Kv1.2, and Kv1.3. Clues to design analogs with enhanced selectivity. J. Biol. Chem. 1999, 274, 35653-35661.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 35653-35661
-
-
Alessandri-Haber, N.1
Lecoq, A.2
Gasparini, S.3
Grangier-Macmath, G.4
Jacquet, G.5
Harvey, A.L.6
De Medeiros, C.7
Rowan, E.G.8
Gola, M.9
Menez, A.10
Crest, M.11
-
62
-
-
0037020077
-
Structure of the BgK-Kv1.1 complex based on distance restraints identified by double mutant cycles. Molecular basis for convergent evolution of Kv1 channel blockers
-
Gilquin, B.; Racape, J.; Wrisch, A.; Visan, V.; Lecoq, A.; Grissmer, S.; Menez, A.; Gasparini, S. Structure of the BgK-Kv1.1 complex based on distance restraints identified by double mutant cycles. Molecular basis for convergent evolution of Kv1 channel blockers. J. Biol. Chem. 2002, 277, 37406-37413.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 37406-37413
-
-
Gilquin, B.1
Racape, J.2
Wrisch, A.3
Visan, V.4
Lecoq, A.5
Grissmer, S.6
Menez, A.7
Gasparini, S.8
-
63
-
-
9144254527
-
Potassium channel blockade by the sea anemone toxin ShK for the treatment of multiple sclerosis and other autoimmune diseases
-
Norton, R. S.; Pennington, M. W.; Wulff, H. Potassium channel blockade by the sea anemone toxin ShK for the treatment of multiple sclerosis and other autoimmune diseases. Curr. Med. Chem. 2004, 11, 3041-3052.
-
(2004)
Curr. Med. Chem.
, vol.11
, pp. 3041-3052
-
-
Norton, R.S.1
Pennington, M.W.2
Wulff, H.3
-
64
-
-
0028865859
-
+ channels
-
+ channels. J. Biol. Chem. 1995, 270, 25121-25126.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 25121-25126
-
-
Schweitz, H.1
Bruhn, T.2
Guillemare, E.3
Moinier, D.4
Lancelin, J.M.5
Beress, L.6
Lazdunski, M.7
-
65
-
-
0032549630
-
Sea anemone peptides with a specific blocking activity against the fast inactivating potassium channel Kv3.4
-
Diochot, S.; Schweitz, H.; Beress, L; Lazdunski, M. Sea anemone peptides with a specific blocking activity against the fast inactivating potassium channel Kv3.4. J. Biol. Chem. 1998, 273, 6744-6749.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 6744-6749
-
-
Diochot, S.1
Schweitz, H.2
Beress, L.3
Lazdunski, M.4
-
66
-
-
0037899621
-
APETx1, a new toxin from the sea anemone Anthopleura elegantissima, blocks voltage-gated human ether-a-go-go-related gene potassium channels
-
Diochot, S.; Loret, E.; Bruhn, T.; Beress, L.; Lazdunski, M. APETx1, a new toxin from the sea anemone Anthopleura elegantissima, blocks voltage-gated human ether-a-go-go-related gene potassium channels. Mol. Pharmacol. 2003, 64, 59-69.
-
(2003)
Mol. Pharmacol.
, vol.64
, pp. 59-69
-
-
Diochot, S.1
Loret, E.2
Bruhn, T.3
Beress, L.4
Lazdunski, M.5
-
67
-
-
0029018362
-
Characterization of a potassium channel toxin from the Caribbean Sea anemone Stichodactyla helianthus
-
Castaneda, O.; Sotolongo, V.; Amor, A. M.; Stocklin, R.; Anderson, A. J.; Harvey, A. L.; Engstrom, A.; Wernstedt, C.; Karlsson, E. Characterization of a potassium channel toxin from the Caribbean Sea anemone Stichodactyla helianthus. Toxicon 1995, 33, 603-613.
-
(1995)
Toxicon
, vol.33
, pp. 603-613
-
-
Castaneda, O.1
Sotolongo, V.2
Amor, A.M.3
Stocklin, R.4
Anderson, A.J.5
Harvey, A.L.6
Engstrom, A.7
Wernstedt, C.8
Karlsson, E.9
-
68
-
-
0027263569
-
A potassium channel toxin from the secretion of the sea anemone Bunodosoma granulifera. Isolation, amino acid sequence and biological activity
-
Aneiros, A.; Garcia, I.; Martinez, J. R.; Harvey, A. L.; Anderson, A. J.; Marshall, D. L.; Engstrom, A.; Hellman, U.; Karlsson, E. A potassium channel toxin from the secretion of the sea anemone Bunodosoma granulifera. Isolation, amino acid sequence and biological activity. Biochim. Biophys. Acta. 1993, 1157, 86-92.
-
(1993)
Biochim. Biophys. Acta.
, vol.1157
, pp. 86-92
-
-
Aneiros, A.1
Garcia, I.2
Martinez, J.R.3
Harvey, A.L.4
Anderson, A.J.5
Marshall, D.L.6
Engstrom, A.7
Hellman, U.8
Karlsson, E.9
-
69
-
-
8044235836
-
A potassium-channel toxin from the sea anemone Bunodosoma granulifera, an inhibitor for Kv1 channels. Revision of the amino acid sequence, disulfide-bridge assignment, chemical synthesis, and biological activity
-
Cotton, J.; Crest, M.; Bouet, F.; Alessandri, N.; Gola, M.; Forest, E.; Karlsson, E.; Castaneda, O.; Harvey, A. L.; Vita, C.; Menez, A. A potassium-channel toxin from the sea anemone Bunodosoma granulifera, an inhibitor for Kv1 channels. Revision of the amino acid sequence, disulfide-bridge assignment, chemical synthesis, and biological activity. Eur. J. Biochem. 1997, 244, 192-202.
-
(1997)
Eur. J. Biochem.
, vol.244
, pp. 192-202
-
-
Cotton, J.1
Crest, M.2
Bouet, F.3
Alessandri, N.4
Gola, M.5
Forest, E.6
Karlsson, E.7
Castaneda, O.8
Harvey, A.L.9
Vita, C.10
Menez, A.11
-
70
-
-
0030885670
-
A new potassium channel toxin from the sea anemone Heteractis magnifica: Isolation, cDNA cloning, and functional expression
-
Gendeh, G. S.; Young, L. C.; de Medeiros, C. L.; Jeyaseelan, K.; Harvey, A. L.; Chung, M. C. A new potassium channel toxin from the sea anemone Heteractis magnifica: isolation, cDNA cloning, and functional expression. Biochemistry 1997, 36, 11461-11471.
-
(1997)
Biochemistry
, vol.36
, pp. 11461-11471
-
-
Gendeh, G.S.1
Young, L.C.2
De Medeiros, C.L.3
Jeyaseelan, K.4
Harvey, A.L.5
Chung, M.C.6
-
71
-
-
0032079657
-
Primary structure of a potassium channel toxin from the sea anemone Actinia equina
-
Minagawa, S.; Ishida, M.; Nagashima, Y.; Shiomi, K. Primary structure of a potassium channel toxin from the sea anemone Actinia equina. FEBS Lett. 1998, 427, 149-151.
-
(1998)
FEBS Lett.
, vol.427
, pp. 149-151
-
-
Minagawa, S.1
Ishida, M.2
Nagashima, Y.3
Shiomi, K.4
-
72
-
-
0031461181
-
Effects of a toxin from the mucus of the Caribbean sea anemone (Bunodosoma granulifera) on the ionic currents of single ventricular mammalian cardiomyocytes
-
Salinas, E. M.; Cebada, J.; Valdes, A.; Garateix, A.; Aneiros, A.; Alvarez, J. L. Effects of a toxin from the mucus of the Caribbean sea anemone (Bunodosoma granulifera) on the ionic currents of single ventricular mammalian cardiomyocytes. Toxicon 1997, 35, 1699-1709.
-
(1997)
Toxicon
, vol.35
, pp. 1699-1709
-
-
Salinas, E.M.1
Cebada, J.2
Valdes, A.3
Garateix, A.4
Aneiros, A.5
Alvarez, J.L.6
-
73
-
-
0031916271
-
Autonomic neurotoxicity of jellyfish and marine animal venoms
-
Burnett, J.W.; Weinrich, D.; Williamson, J.A.; Fenner, P.J.; Lutz, L.L.; Bloom, D.A. Autonomic neurotoxicity of jellyfish and marine animal venoms. Clin. Autonomic Res. 1998, 8, 125-130.
-
(1998)
Clin. Autonomic Res.
, vol.8
, pp. 125-130
-
-
Burnett, J.W.1
Weinrich, D.2
Williamson, J.A.3
Fenner, P.J.4
Lutz, L.L.5
Bloom, D.A.6
-
74
-
-
0036229004
-
Calcium-dependent smooth muscle excitatory effect elicited by the venom of the hydrocoral Millepora complanata
-
Rojas, A.; Torres, M.; Rojas, J.I; Feregrino, A.; Heimer-de la Cotera, E. Calcium-dependent smooth muscle excitatory effect elicited by the venom of the hydrocoral Millepora complanata. Toxicon 2002, 40, 777-785.
-
(2002)
Toxicon
, vol.40
, pp. 777-785
-
-
Rojas, A.1
Torres, M.2
Rojas, J.I.3
Feregrino, A.4
Heimer-de La Cotera, E.5
-
75
-
-
0024266338
-
Effect of sea nettle (Chrysaora quinquecirrha) venom on isolated rat aorta
-
Lin, W.W; Lee, C.Y.; Burnett, J.W. Effect of sea nettle (Chrysaora quinquecirrha) venom on isolated rat aorta. Toxicon 1988, 26, 1209-1212.
-
(1988)
Toxicon
, vol.26
, pp. 1209-1212
-
-
Lin, W.W.1
Lee, C.Y.2
Burnett, J.W.3
-
76
-
-
0020611550
-
Ionic channels induced by sea nettle toxin in the nodal membrane
-
Dubois, J.M.; Tanguy, J; Burnett, J.W. Ionic channels induced by sea nettle toxin in the nodal membrane. Biophys. J. 1983, 42, 199-202.
-
(1983)
Biophys. J.
, vol.42
, pp. 199-202
-
-
Dubois, J.M.1
Tanguy, J.2
Burnett, J.W.3
|