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Volumn 27, Issue 4, 2006, Pages 201-210

Effects of HER2-binding affibody molecules on intracellular signaling pathways

Author keywords

Affibody; Akt; Erk; HER2; PLC 1; Signal transduction

Indexed keywords

(Z HER2:4) 2 AFFIBODY; AFFIBODY; EPIDERMAL GROWTH FACTOR RECEPTOR 2; HER2 BINDING AFFIBODY; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHOLIPASE C GAMMA1; PROTEIN KINASE B; TRASTUZUMAB; TYROSINE KINASE RECEPTOR; UNCLASSIFIED DRUG; Z HER2:342 AFFIBODY;

EID: 33646739287     PISSN: 10104283     EISSN: None     Source Type: Journal    
DOI: 10.1159/000093023     Document Type: Article
Times cited : (25)

References (28)
  • 1
    • 0042203565 scopus 로고    scopus 로고
    • SH2 and PTB domains in tyrosine kinase signaling
    • Schlessinger J, Lemmon MA: SH2 and PTB domains in tyrosine kinase signaling. Sci STKE 2003;2003:RE12.
    • (2003) Sci STKE , vol.2003
    • Schlessinger, J.1    Lemmon, M.A.2
  • 3
    • 0032752063 scopus 로고    scopus 로고
    • Cellular survival: A play in three Akts
    • Datta SR, Brunet A, Greenberg ME: Cellular survival: a play in three Akts. Genes Dev 1999;13:2905-2927.
    • (1999) Genes Dev , vol.13 , pp. 2905-2927
    • Datta, S.R.1    Brunet, A.2    Greenberg, M.E.3
  • 4
    • 0347997608 scopus 로고    scopus 로고
    • MAPK signal pathways in the regulation of cell proliferation in mammalian cells
    • Zhang W, Liu HT: MAPK signal pathways in the regulation of cell proliferation in mammalian cells. Cell Res 2002;12:9-18.
    • (2002) Cell Res , vol.12 , pp. 9-18
    • Zhang, W.1    Liu, H.T.2
  • 5
    • 0037862104 scopus 로고    scopus 로고
    • Phospholipase C-gamma1 in tumor progression
    • Wells A, Grandis JR: Phospholipase C-gamma1 in tumor progression. Clin Exp Metastasis 2003;20:285-290.
    • (2003) Clin Exp Metastasis , vol.20 , pp. 285-290
    • Wells, A.1    Grandis, J.R.2
  • 6
    • 0141592701 scopus 로고    scopus 로고
    • Epidermal growth factor receptor-stimulated activation of phospholipase Cgamma-1 promotes invasion of head and neck squamous cell carcinoma
    • Thomas SM, Coppelli FM, Wells A, Gooding WE, Song J, Kassis J, Drenning SD, Grandis JR: Epidermal growth factor receptor-stimulated activation of phospholipase Cgamma-1 promotes invasion of head and neck squamous cell carcinoma. Cancer Res 2003;63:5629-5635.
    • (2003) Cancer Res , vol.63 , pp. 5629-5635
    • Thomas, S.M.1    Coppelli, F.M.2    Wells, A.3    Gooding, W.E.4    Song, J.5    Kassis, J.6    Drenning, S.D.7    Grandis, J.R.8
  • 8
    • 0025687686 scopus 로고
    • The normal erbB-2 product is an atypical receptor-like tyrosine kinase with constitutive activity in the absence of ligand
    • Lonardo F, Di Marco E, King CR, Pierce JH, Segatto O, Aaronson SA, Di Fiore PP: The normal erbB-2 product is an atypical receptor-like tyrosine kinase with constitutive activity in the absence of ligand. New Biol 1990;2:992-1003.
    • (1990) New Biol , vol.2 , pp. 992-1003
    • Lonardo, F.1    Di Marco, E.2    King, C.R.3    Pierce, J.H.4    Segatto, O.5    Aaronson, S.A.6    Di Fiore, P.P.7
  • 9
    • 0037699294 scopus 로고    scopus 로고
    • Strategies to target HER2/neu overexpression for cancer therapy
    • Chen JS, Lan K, Hung MC: Strategies to target HER2/neu overexpression for cancer therapy. Drug Resist Updat 2003;6:129-136.
    • (2003) Drug Resist Updat , vol.6 , pp. 129-136
    • Chen, J.S.1    Lan, K.2    Hung, M.C.3
  • 11
    • 0141645488 scopus 로고    scopus 로고
    • Mechanism of action of anti-HER2 monoclonal antibodies: Scientific update on trastuzumab and 2C4
    • Albanell J, Codony J, Rovira A, Mellado B, Gascon P: Mechanism of action of anti-HER2 monoclonal antibodies: scientific update on trastuzumab and 2C4. Adv Exp Med Biol 2003;532:253-268.
    • (2003) Adv Exp Med Biol , vol.532 , pp. 253-268
    • Albanell, J.1    Codony, J.2    Rovira, A.3    Mellado, B.4    Gascon, P.5
  • 14
    • 22344445345 scopus 로고    scopus 로고
    • In vitro characterization of a bivalent anti-HER-2 affibody with potential for radionuclide based diagnostics
    • Steffen AC, Wikman M, Tolmachev V, Adams G, Ståhl S, Carlsson J: In vitro characterization of a bivalent anti-HER-2 affibody with potential for radionuclide based diagnostics. Cancer Biother Radiopharm 2005;20:233-242.
    • (2005) Cancer Biother Radiopharm , vol.20 , pp. 233-242
    • Steffen, A.C.1    Wikman, M.2    Tolmachev, V.3    Adams, G.4    Ståhl, S.5    Carlsson, J.6
  • 16
    • 0033619142 scopus 로고    scopus 로고
    • Phosphorylation of Shc by Src family kinases is necessary for stem cell factor receptor/c-kit mediated activation of the Ras/MAP kinase pathway and c-fos induction
    • Lennartsson J, Blume-Jensen P, Hermanson M, Ponten E, Carlberg M, Ronnstrand L: Phosphorylation of Shc by Src family kinases is necessary for stem cell factor receptor/c-kit mediated activation of the Ras/MAP kinase pathway and c-fos induction. Oncogene 1999;18:5546-5553.
    • (1999) Oncogene , vol.18 , pp. 5546-5553
    • Lennartsson, J.1    Blume-Jensen, P.2    Hermanson, M.3    Ponten, E.4    Carlberg, M.5    Ronnstrand, L.6
  • 17
    • 0038297647 scopus 로고    scopus 로고
    • Overactivation of phospholipase C-gammal renders platelet-derived growth factor beta-receptor-expressing cells independent of the phosphatidylinositol 3-kinase pathway for chemotaxis
    • Ronnstrand L, Siegbahn A, Rorsman C, Johnell M, Hansen K, Heldin CH: Overactivation of phospholipase C-gammal renders platelet-derived growth factor beta-receptor-expressing cells independent of the phosphatidylinositol 3-kinase pathway for chemotaxis. J Biol Chem 1999;274:22089-22094.
    • (1999) J Biol Chem , vol.274 , pp. 22089-22094
    • Ronnstrand, L.1    Siegbahn, A.2    Rorsman, C.3    Johnell, M.4    Hansen, K.5    Heldin, C.H.6
  • 18
    • 0036835585 scopus 로고    scopus 로고
    • EGF and dextran-conjugated EGF induces differential phosphorylation of the EGF receptor
    • Hagg M, Liljegren A, Carlsson J, Ronnstrand L, Lennartsson J: EGF and dextran-conjugated EGF induces differential phosphorylation of the EGF receptor. Int J Mol Med 2002;10:655-659.
    • (2002) Int J Mol Med , vol.10 , pp. 655-659
    • Hagg, M.1    Liljegren, A.2    Carlsson, J.3    Ronnstrand, L.4    Lennartsson, J.5
  • 20
    • 0034630167 scopus 로고    scopus 로고
    • Induction of apoptosis by cancer chemotherapy
    • Kaufmann SH, Earnshaw WC: Induction of apoptosis by cancer chemotherapy. Exp Cell Res 2000;256:42-49.
    • (2000) Exp Cell Res , vol.256 , pp. 42-49
    • Kaufmann, S.H.1    Earnshaw, W.C.2
  • 22
    • 12544250381 scopus 로고    scopus 로고
    • Genes affecting the cell cycle, growth, maintenance, and drug sensitivity are preferentially regulated by anti-HER2 antibody through phosphatidylinositol 3-kinase-AKT signaling
    • Le XF, Lammayot A, Gold D, Lu Y, Mao W, Chang T, Patel A, Mills GB, Bast RC Jr: Genes affecting the cell cycle, growth, maintenance, and drug sensitivity are preferentially regulated by anti-HER2 antibody through phosphatidylinositol 3-kinase-AKT signaling. J Biol Chem 2005;280:2092-2104.
    • (2005) J Biol Chem , vol.280 , pp. 2092-2104
    • Le, X.F.1    Lammayot, A.2    Gold, D.3    Lu, Y.4    Mao, W.5    Chang, T.6    Patel, A.7    Mills, G.B.8    Bast Jr., R.C.9
  • 23
    • 3242686392 scopus 로고    scopus 로고
    • Sensitization of breast cancer cells to radiation by trastuzumab
    • Liang K, Lu Y, Jin W, Ang KK, Milas L, Fan Z: Sensitization of breast cancer cells to radiation by trastuzumab. Mol Cancer Ther 2003;2:1113-1120.
    • (2003) Mol Cancer Ther , vol.2 , pp. 1113-1120
    • Liang, K.1    Lu, Y.2    Jin, W.3    Ang, K.K.4    Milas, L.5    Fan, Z.6
  • 24
    • 0035977185 scopus 로고    scopus 로고
    • Association of c-Raf expression with survival and its targeting with antisense oligonucleotides in ovarian cancer
    • McPhillips F, Mullen P, Monia BP, Ritchie AA, Dorr FA, Smyth JF, Langdon SP: Association of c-Raf expression with survival and its targeting with antisense oligonucleotides in ovarian cancer. Br J Cancer 2001;85:1753-1758.
    • (2001) Br J Cancer , vol.85 , pp. 1753-1758
    • McPhillips, F.1    Mullen, P.2    Monia, B.P.3    Ritchie, A.A.4    Dorr, F.A.5    Smyth, J.F.6    Langdon, S.P.7
  • 25
    • 0029791504 scopus 로고    scopus 로고
    • Mutation of a Src phosphorylation site in the PDGF beta-receptor leads to increased PDGF-stimulated chemotaxis but decreased mitogenesis
    • Hansen K, Johnell M, Siegbahn A, Rorsman C, Engstrom U, Wernstedt C, Heldin CH, Ronnstrand L: Mutation of a Src phosphorylation site in the PDGF beta-receptor leads to increased PDGF-stimulated chemotaxis but decreased mitogenesis. EMBO J 1996;15:5299-5313.
    • (1996) EMBO J , vol.15 , pp. 5299-5313
    • Hansen, K.1    Johnell, M.2    Siegbahn, A.3    Rorsman, C.4    Engstrom, U.5    Wernstedt, C.6    Heldin, C.H.7    Ronnstrand, L.8
  • 26
    • 0842346270 scopus 로고    scopus 로고
    • Do phosphoinositide 3-kinases direct lymphocyte navigation?
    • Ward SG: Do phosphoinositide 3-kinases direct lymphocyte navigation? Trends Immunol 2004;25:67-74.
    • (2004) Trends Immunol , vol.25 , pp. 67-74
    • Ward, S.G.1
  • 27
    • 21444454939 scopus 로고    scopus 로고
    • Blocking of PI3K/Akt pathway enhances apoptosis induced by SN-38, an active form of CPT-11, in human hepatoma cells
    • Koizumi N, Hatano E, Nitta T, Tada M, Harada N, Taura K, Ikai I, Shimahara Y: Blocking of PI3K/Akt pathway enhances apoptosis induced by SN-38, an active form of CPT-11, in human hepatoma cells. Int J Oncol 2005;26:1301-1306.
    • (2005) Int J Oncol , vol.26 , pp. 1301-1306
    • Koizumi, N.1    Hatano, E.2    Nitta, T.3    Tada, M.4    Harada, N.5    Taura, K.6    Ikai, I.7    Shimahara, Y.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.