Mutation of a Src phosphorylation site in the PDGF β-receptor leads to increased PDGF-stimulated chemotaxis but decreased mitogenesis

EMBO Journal

Volumn 15, Issue 19, 1996, Pages 5299-5313

  Hansen, Klaus ^a,c   Johnell, Matilda ^b   Siegbahn, Agneta ^b   Rorsman, Charlotte ^a   Engström, Ulla ^a   Wernstedt, Christer ^a   Heldin, Carl Henrik ^a   Rönnstrand, Lars ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b UPPSALA UNIVERSITY HOSPITAL   (Sweden)

^c DANISH CANCER SOCIETY RESEARCH CENTER   (Denmark)

Author keywords

c Src; Chemotaxis; PDGF receptor; Phospholipase C ; Phosphorylation

Indexed keywords

ACTIN; MUTANT PROTEIN; PHENYLALANINE; PHOSPHATIDYLINOSITOL KINASE; PHOSPHOLIPASE C; PLATELET DERIVED GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR RECEPTOR; PROTEIN KINASE C; PROTEIN TYROSINE KINASE; TYROSINE;

ARTICLE; CELL MOTILITY; CHEMOTAXIS; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; GENE MUTATION; HUMAN; HUMAN CELL; MITOGENESIS; MITOGENICITY; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

EID: 0029791504     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1002/j.1460-2075.1996.tb00915.x     Document Type: Article

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