Disruption of the long-range GPIIIa Cys5-Cys435 disulfide bond results in the production of constitutively active GPIIb-IIIa (αIIbβ3) integrin complexes

Blood

Volumn 100, Issue 6, 2002, Pages 2094-2101

  Sun, Qi Hong ^a,b   Liu, Chao Yan ^a,b   Wang, Ronggang ^a,b   Paddock, Cathy ^a,b   Newman, Peter J ^a,b  

^a BLOOD RESEARCH INSTITUTE   (United States)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE; FIBRINOGEN; FIBRINOGEN RECEPTOR; INTEGRIN; MONOCLONAL ANTIBODY; THROMBOCYTE ANTIBODY; VON WILLEBRAND FACTOR;

ANIMAL CELL; ARTICLE; BINDING SITE; CELL ADHESION; CHO CELL; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; DISULFIDE BOND; GENETIC TRANSFECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN PHOSPHORYLATION; RECEPTOR UPREGULATION; THROMBOCYTE AGGREGATION;

EID: 0037105364     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2002-02-0418     Document Type: Article

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