Calcium is a cofactor of polymerization but inhibits pyrophosphorolysis by the Sulfolobus solfataricus DNA polymerase Dpo4

Biochemistry

Volumn 45, Issue 19, 2006, Pages 5949-5956

  Irimia, Adriana ^a   Zang, Hong ^a   Loukachevitch, Lioudmila V ^a   Eoff, Robert L ^a   Guengerich, F Peter ^a   Egli, Martin ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; COMPLEXATION; DNA; ENZYMES; MICROSTRUCTURE; POLYMERIZATION;

DNA POLYMERASE DPO4; EXONUCLEASE ACTIVITY; PYROPHOSPHOROLYSIS; SULFOLOBUS SOLFATARICUS;

CALCIUM COMPOUNDS;

8 HYDROXYGUANINE; BARIUM ION; CALCIUM; COBALT; COPPER ION; DNA POLYMERASE; DNA POLYMERASE DPO4; EXONUCLEASE; MAGNESIUM ION; NICKEL; UNCLASSIFIED DRUG; ZINC ION;

ARTICLE; COMPLEX FORMATION; CRYSTAL STRUCTURE; DNA TEMPLATE; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME POLYMORPHISM; ENZYME SUBSTRATE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN DNA BINDING; PROTEIN FAMILY; SULFOLOBUS SOLFATARICUS;

BASE SEQUENCE; BIOPOLYMERS; CALCIUM; CATIONS, DIVALENT; DIPHOSPHATES; DNA PRIMERS; DNA-DIRECTED DNA POLYMERASE; MODELS, MOLECULAR; SULFOLOBUS SOLFATARICUS;

EUKARYOTA; SULFOLOBUS SOLFATARICUS;

EID: 33646594153     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi052511+     Document Type: Article

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