Neuropilin1 is a direct downstream target of Nurr1 in the developing brain stem

Journal of Neurochemistry

Volumn 97, Issue 5, 2006, Pages 1403-1411

  Hermanson, Elisabet ^a   Borgius, Lotta ^a   Bergsland, Maria ^a   Joodmardi, Eliza ^a   Perlmann, Thomas ^a,b  

^a LUDWIG INSTITUTE FOR CANCER RESEARCH   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Brain stem; Development; Gene expression; Neuropilin1; Nurr1; Orphan nuclear receptor

Indexed keywords

NEUROPILIN; NUCLEAR RECEPTOR RELATED FACTOR 1;

ANGIOGENESIS; ANIMAL CELL; ARTICLE; BINDING SITE; BRAIN DEVELOPMENT; BRAIN STEM; CELL FUNCTION; CELL LINE; CELL STRAIN MN9D; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; GENE; GENE CONTROL; GENE EXPRESSION; GENE IDENTIFICATION; IN SITU HYBRIDIZATION; MESENCEPHALON; MOUSE; NERVE CELL DIFFERENTIATION; NERVE FIBER GROWTH; NONHUMAN; NRP1 GENE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING; PROTEIN EXPRESSION; RESPIRATORY FUNCTION; SIGNAL TRANSDUCTION;

ANIMALS; BINDING SITES; BRAIN STEM; CELL DIFFERENTIATION; CELL LINE; DNA-BINDING PROTEINS; DOWN-REGULATION; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GROWTH CONES; MICE; MICE, KNOCKOUT; NEOVASCULARIZATION, PHYSIOLOGIC; NEUROPILIN-1; PROMOTER REGIONS (GENETICS); TRANSCRIPTION FACTORS; UP-REGULATION; VAGUS NERVE;

EID: 33646587985     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2006.03829.x     Document Type: Article

References (40)

1. Aranda A Pascual A 2001 Nuclear hormone receptors and gene expression PhysiolRev 81 1269 1304
2. Arkenbout EK van Bragt M Eldering E van Bree C Grimbergen JM Quax PH Pannekoek H de Vries CJ 2003 TR3 orphan receptor is expressed in vascular endothelial cells and mediates cell cycle arrest Arterioscler Thromb Vasc Biol 23 1535 1540
3. Castillo SO Baffi JS Palkovits M Goldstein DS Kopin IJ Witta J Magnuson MA Nikodem VM 1998 Dopamine biosynthesis is selectively abolished in substantia nigra/ventral tegmental area but not in hypothalamic neurons in mice with targeted disruption of the Nurr1 gene Mol Cell Neurosci 11 36 46
4. Castro DS Hermanson E Joseph B Wallen A Aarnisalo P Heller A Perlmann T 2001 Induction of cell cycle arrest and morphological differentiation by Nurr1 and retinoids in dopamine MN9D cells JBiolChem 276 43 277 43 284
5. Chen C Li M Chai H Yang H Fisher WE Yao Q 2005 Roles of Neuropilins in Neuronal Development, Angiogenesis, and Cancers World JSurg 29 271 275
6. Choi HK Won LA Kontur PJ Hammond DN Fox AP Wainer BH Hoffmann PC Heller A 1991 Immortalization of embryonic mesencephalic dopaminergic neurons by somatic cell fusion Brain Res 552 67 76
7. Crispino M Tocco G Feldman JD Herschman HR Baudry M 1998 Nurr1 mRNA expression in neonatal and adult rat brain following kainic acid-induced seizure activity Brain ResMol Brain Res 59 178 188
8. Forman BM Umesono K Chen J Evans RM 1995 Unique response pathways are established by allosteric interactions among nuclear hormone receptors Cell 81 541 550
9. Hermanson E Joseph B Castro D Lindqvist E Aarnisalo P Wallen A Benoit G Hengerer B Olson L Perlmann T 2003 Nurr1 regulates dopamine synthesis and storage in MN9D dopamine cells Exp Cell Res 288 324 334
10. Joseph B Wallen-Mackenzie A Benoit G Murata T Joodmardi E Okret S Perlmann T 2003 p57 (Kip2) cooperates with Nurr1 in developing dopamine cells ProcNatl AcadSciUSA 100 15 619 15 624
11. Kawakami A Kitsukawa T Takagi S Fujisawa H 1996 Developmentally regulated expression of a cell surface protein, neuropilin, in the mouse nervous system JNeurobiol 29 1 17
12. Kawasaki T Kitsukawa T Bekku Y Matsuda Y Sanbo M Yagi T Fujisawa H 1999 A requirement for neuropilin-1 in embryonic vessel formation Development 126 4895 4902
13. Kitsukawa T Shimizu M Sanbo M Hirata T Taniguchi M Bekku Y Yagi T Fujisawa H 1997 Neuropilin-semaphorin III/ d -mediated chemorepulsive signals play a crucial role in peripheral nerve projection in mice Neuron 19 995 1005
14. Kitsukawa T Shimono A Kawakami A Kondoh H Fujisawa H 1995 Overexpression of a membrane protein, neuropilin, in chimeric mice causes anomalies in the cardiovascular system, nervous system and limbs Development 121 4309 4318
15. Kliewer SA Lehmann JM Willson TM 1999 Orphan nuclear receptors: shifting endocrinology into reverse Science 284 757 760
16. Law SW Conneely OM DeMayo FJ O'Malley BW 1992 Identification of a new brain-specific transcription factor, NURR1 Mol Endocrinol 6 2129 2135
17. Lin TN Chen JJ Wang SJ Cheng JT Chi SI Shyu AB Sun GY Hsu CY 1996 Expression of NGFI-B mRNA in a rat focal cerebral ischemia-reperfusion model Brain ResMol Brain Res 43 149 156
18. Liu D Jia H Holmes DI Stannard A Zachary I 2003 Vascular endothelial growth factor-regulated gene expression in endothelial cells: KDR-mediated induction of Egr3 and the related nuclear receptors Nur77, Nurr1, and Nor1 Arterioscler Thromb Vasc Biol 23 2002 2007
19. Mangelsdorf DJ Thummel C Beato M Herrlich P Schutz G Umesono K Blumberg B Kastner P Mark M Chambon P et al. 1995 The nuclear receptor superfamily: the second decade Cell 83 835 839
20. Matthews J Wihlen B Thomsen J Gustafsson JA 2005 Aryl hydrocarbon receptor-mediated transcription: ligand-dependent recruitment of estrogen receptor alpha to 2,3,7,8-tetrachlorodibenzo-p-dioxin-responsive promoters Mol Cell Biol 25 5317 5328
21. Milbrandt J 1988 Nerve growth factor induces a gene homologous to the glucocorticoid receptor gene Neuron 1 183 188
22. Nsegbe E Wallen-Mackenzie A Dauger S Roux JC Shvarev Y Lagercrantz H Perlmann T Herlenius E 2004 Congenital hypoventilation and impaired hypoxic response in Nurr1 mutant mice J Physiol 556 43 59
23. Pellagatti A Vetrie D Langford CF Gama S Eagleton H Wainscoat JS Boultwood J 2003 Gene expression profiling in polycythemia vera using cDNA microarray technology Cancer Res 63 3940 3944
24. Perlmann T Jansson L 1995 A novel pathway for vitamin A signaling mediated by RXR heterodimerization with NGFI-B and NURR1 Genes Dev 9 769 782
25. Philips A Lesage S Gingras R Maira MH Gauthier Y Hugo P Drouin J 1997 Novel dimeric Nur77 signaling mechanism in endocrine and lymphoid cells Mol Cell Biol 17 5946 5951
26. Sacchetti P Brownschidle LA Granneman JG Bannon MJ 1999 Characterization of the 5′-flanking region of the human dopamine transporter gene Brain ResMol Brain Res 74 167 174
27. Sacchetti P Mitchell TR Granneman JG Bannon MJ 2001 Nurr1 enhances transcription of the human dopamine transporter gene through a novel mechanism JNeurochem 76 1565 1572
28. Sakurada K Ohshima-Sakurada M Palmer TD Gage FH 1999 Nurr1, an orphan nuclear receptor, is a transcriptional activator of endogenous tyrosine hydroxylase in neural progenitor cells derived from the adult brain Development 126 4017 4026
29. Saucedo-Cardenas O Conneely OM 1996 Comparative distribution of NURR1 and NUR77 nuclear receptors in the mouse central nervous system JMol Neurosci 7 51 63
30. Saucedo-Cardenas O Quintana-Hau JD Le WD Smidt MP Cox JJ De Mayo F Burbach JP Conneely OM 1998 Nurr1 is essential for the induction of the dopaminergic phenotype and the survival of ventral mesencephalic late dopaminergic precursor neurons ProcNatl AcadSciUSA 95 4013 4018
31. Soker S 2001 Neuropilin in the midst of cell migration and retraction IntJBiochemCell Biol 33 433 437
32. Soker S Takashima S Miao HQ Neufeld G Klagsbrun M 1998 Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor Cell 92 735 745
33. Spender LC Cornish GH Sullivan A Farrell PJ 2002 Expression of transcription factor AML-2 (RUNX3, CBF (alpha)-3) is induced by Epstein-Barr virus EBNA-2 and correlates with the B-cell activation phenotype JVirol 76 4919 4927
34. Wallen AA Castro DS Zetterstrom RH Karlen M Olson L Ericson J Perlmann T 2001 Orphan nuclear receptor nurr1 is essential for ret expression in midbrain dopamine neurons and in the brain stem Mol Cell Neurosci 18 649 663
35. Wang Z Benoit G Liu J Prasad S Aarnisalo P Liu X Xu H Walker NP Perlmann T 2003 Structure and function of Nurr1 identifies a class of ligand-independent nuclear receptors Nature 423 555 560
36. de Wet JR Wood KV DeLuca M Helinski DR Subramani S 1987 Firefly luciferase gene: structure and expression in mammalian cells Mol Cell Biol 7 725 737
37. Wilson TE Fahrner TJ Johnston M Milbrandt J 1991 Identification of the DNA binding site for NGFI-B by genetic selection in yeast Science 252 1296 1300
38. Wilson TE Fahrner TJ Milbrandt J 1993 The orphan receptors NGFI-B and steroidogenic factor 1 establish monomer binding as a third paradigm of nuclear receptor-DNA interaction Mol Cell Biol 13 5794 5804
39. Zetterstrom RH Solomin L Jansson L Hoffer BJ Olson L Perlmann T 1997 Dopamine neuron agenesis in Nurr1-deficient mice Science 276 248 250
40. Zetterstrom RH Solomin L Mitsiadis T Olson L Perlmann T 1996 Retinoid X receptor heterodimerization and developmental expression distinguish the orphan nuclear receptors NGFI-B, Nurr1, and Nor1 Mol Endocrinol 10 1656 1666