메뉴 건너뛰기




Volumn 33, Issue 4, 2006, Pages 555-563

The serotonin transporter in rhesus monkey brain: comparison of DASB and citalopram binding sites

Author keywords

Autoradiography; Citalopram; DASB; Rhesus monkey; SERT; SSRI

Indexed keywords

CARBON 11; CITALOPRAM H 3; FLUOXETINE; N,N DIMETHYL 2 (2 AMINO 4 CYANOPHENYLTHIO)BENZYLAMINE C 11; N,N DIMETHYL 2 (2 AMINO 4 CYANOPHENYLTHIO)BENZYLAMINE H 3; RADIOLIGAND; SEROTONIN TRANSPORTER; SEROTONIN UPTAKE INHIBITOR; UNCLASSIFIED DRUG;

EID: 33646587965     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2006.02.007     Document Type: Article
Times cited : (19)

References (34)
  • 1
    • 0028671921 scopus 로고
    • Development of PET/SPECT ligands for the serotonin transporter
    • Scheffel U., et al. Development of PET/SPECT ligands for the serotonin transporter. NIDA Res Monogr 138 (1994) 111-130
    • (1994) NIDA Res Monogr , vol.138 , pp. 111-130
    • Scheffel, U.1
  • 2
    • 7444220628 scopus 로고    scopus 로고
    • Advances in in vivo imaging of serotonergic neurons in neuropsychiatric disorders
    • Hesse S., et al. Advances in in vivo imaging of serotonergic neurons in neuropsychiatric disorders. Neurosci Biobehav Rev 28 6 (2004) 547-563
    • (2004) Neurosci Biobehav Rev , vol.28 , Issue.6 , pp. 547-563
    • Hesse, S.1
  • 3
    • 10044278067 scopus 로고    scopus 로고
    • Brain serotonin transporter binding potential measured with carbon 11-labeled DASB positron emission tomography: effects of major depressive episodes and severity of dysfunctional attitudes
    • Meyer J.H., et al. Brain serotonin transporter binding potential measured with carbon 11-labeled DASB positron emission tomography: effects of major depressive episodes and severity of dysfunctional attitudes. Arch Gen Psychiatry 61 12 (2004) 1271-1279
    • (2004) Arch Gen Psychiatry , vol.61 , Issue.12 , pp. 1271-1279
    • Meyer, J.H.1
  • 4
    • 13844313475 scopus 로고    scopus 로고
    • Potential of [11C]DASB for measuring endogenous serotonin with PET: binding studies
    • Lundquist P., et al. Potential of [11C]DASB for measuring endogenous serotonin with PET: binding studies. Nucl Med Biol 32 2 (2005) 129-136
    • (2005) Nucl Med Biol , vol.32 , Issue.2 , pp. 129-136
    • Lundquist, P.1
  • 5
    • 0033765742 scopus 로고    scopus 로고
    • Imaging the serotonin transporter with positron emission tomography: initial human studies with [11C]DAPP and [11C]DASB
    • Houle S., et al. Imaging the serotonin transporter with positron emission tomography: initial human studies with [11C]DAPP and [11C]DASB. Eur J Nucl Med 27 11 (2000) 1719-1722
    • (2000) Eur J Nucl Med , vol.27 , Issue.11 , pp. 1719-1722
    • Houle, S.1
  • 6
    • 0034632763 scopus 로고    scopus 로고
    • Novel radiotracers for imaging the serotonin transporter by positron emission tomography: synthesis, radiosynthesis, and in vitro and ex vivo evaluation of (11)C-labeled 2-(phenylthio)araalkylamines
    • Wilson A.A., et al. Novel radiotracers for imaging the serotonin transporter by positron emission tomography: synthesis, radiosynthesis, and in vitro and ex vivo evaluation of (11)C-labeled 2-(phenylthio)araalkylamines. J Med Chem 43 16 (2000) 3103-3110
    • (2000) J Med Chem , vol.43 , Issue.16 , pp. 3103-3110
    • Wilson, A.A.1
  • 7
    • 0035999180 scopus 로고    scopus 로고
    • In vitro and in vivo characterisation of [11C]-DASB: a probe for in vivo measurements of the serotonin transporter by positron emission tomography
    • Wilson A.A., et al. In vitro and in vivo characterisation of [11C]-DASB: a probe for in vivo measurements of the serotonin transporter by positron emission tomography. Nucl Med Biol 29 5 (2002) 509-515
    • (2002) Nucl Med Biol , vol.29 , Issue.5 , pp. 509-515
    • Wilson, A.A.1
  • 8
    • 4444332553 scopus 로고    scopus 로고
    • DASB - in vitro binding characteristics on human recombinant monoamine transporters with regard to its potential as positron emission tomography (PET) tracer
    • Hummerich R., et al. DASB - in vitro binding characteristics on human recombinant monoamine transporters with regard to its potential as positron emission tomography (PET) tracer. J Neurochem 90 5 (2004) 1218-1226
    • (2004) J Neurochem , vol.90 , Issue.5 , pp. 1218-1226
    • Hummerich, R.1
  • 9
    • 1642498182 scopus 로고    scopus 로고
    • Pharmacological and genetic characterization of two selective serotonin transporter ligands: 2-[2-(dimethylaminomethylphenylthio)]-5-fluoromethylphenylamine (AFM) and 3-amino-4-[2-(dimethylaminomethyl-phenylthio)]benzonitrile (DASB)
    • Li Q., et al. Pharmacological and genetic characterization of two selective serotonin transporter ligands: 2-[2-(dimethylaminomethylphenylthio)]-5-fluoromethylphenylamine (AFM) and 3-amino-4-[2-(dimethylaminomethyl-phenylthio)]benzonitrile (DASB). J Pharmacol Exp Ther 308 2 (2004) 481-486
    • (2004) J Pharmacol Exp Ther , vol.308 , Issue.2 , pp. 481-486
    • Li, Q.1
  • 10
    • 0036842463 scopus 로고    scopus 로고
    • Comparative evaluation in nonhuman primates of five PET radiotracers for imaging the serotonin transporters: [11C]McN 5652, [11C]ADAM, [11C]DASB, [11C]DAPA, and [11C]AFM
    • Huang H.D., Narendran R., Sudo Y., Chatterjee R., Bae S.A., Mawlawi O., et al. Comparative evaluation in nonhuman primates of five PET radiotracers for imaging the serotonin transporters: [11C]McN 5652, [11C]ADAM, [11C]DASB, [11C]DAPA, and [11C]AFM. J Cereb Blood Flow Metab 22 11 (2002) 1377-1398
    • (2002) J Cereb Blood Flow Metab , vol.22 , Issue.11 , pp. 1377-1398
    • Huang, H.D.1    Narendran, R.2    Sudo, Y.3    Chatterjee, R.4    Bae, S.A.5    Mawlawi, O.6
  • 11
    • 10644297481 scopus 로고    scopus 로고
    • Biodistribution and radiation dosimetry of [11C]DASB in baboons
    • Belanger M.J., et al. Biodistribution and radiation dosimetry of [11C]DASB in baboons. Nucl Med Biol 31 8 (2004) 1097-1102
    • (2004) Nucl Med Biol , vol.31 , Issue.8 , pp. 1097-1102
    • Belanger, M.J.1
  • 12
    • 0035157572 scopus 로고    scopus 로고
    • Occupancy of serotonin transporters by paroxetine and citalopram during treatment of depression: a [(11)C]DASB PET imaging study
    • Meyer J.H., et al. Occupancy of serotonin transporters by paroxetine and citalopram during treatment of depression: a [(11)C]DASB PET imaging study. Am J Psychiatry 158 11 (2001) 1843-1849
    • (2001) Am J Psychiatry , vol.158 , Issue.11 , pp. 1843-1849
    • Meyer, J.H.1
  • 13
    • 2442457724 scopus 로고    scopus 로고
    • Serotonin transporter occupancy of five selective serotonin reuptake inhibitors at different doses: an [11C]DASB positron emission tomography study
    • Meyer J.H., et al. Serotonin transporter occupancy of five selective serotonin reuptake inhibitors at different doses: an [11C]DASB positron emission tomography study. Am J Psychiatry 161 5 (2004) 826-835
    • (2004) Am J Psychiatry , vol.161 , Issue.5 , pp. 826-835
    • Meyer, J.H.1
  • 14
    • 2542492338 scopus 로고    scopus 로고
    • Comparative evaluation of serotonin transporter radioligands 11C-DASB and 11C-McN 5652 in healthy humans
    • Frankle W.G., et al. Comparative evaluation of serotonin transporter radioligands 11C-DASB and 11C-McN 5652 in healthy humans. J Nucl Med 45 4 (2004) 682-694
    • (2004) J Nucl Med , vol.45 , Issue.4 , pp. 682-694
    • Frankle, W.G.1
  • 15
    • 20444418603 scopus 로고    scopus 로고
    • Serotonin transporter availability in patients with schizophrenia: a positron emission tomography imaging study with [11C]DASB
    • Frankle W.G., et al. Serotonin transporter availability in patients with schizophrenia: a positron emission tomography imaging study with [11C]DASB. Biol Psychiatry 57 12 (2005) 1510-1516
    • (2005) Biol Psychiatry , vol.57 , Issue.12 , pp. 1510-1516
    • Frankle, W.G.1
  • 16
    • 0037216396 scopus 로고    scopus 로고
    • Pharmacological characterization of N,N-dimethyl-2-(2-amino-4-methylphenyl thio)benzylamine as a ligand of the serotonin transporter with high affinity and selectivity
    • Chalon S., et al. Pharmacological characterization of N,N-dimethyl-2-(2-amino-4-methylphenyl thio)benzylamine as a ligand of the serotonin transporter with high affinity and selectivity. J Pharmacol Exp Ther 304 1 (2003) 81-87
    • (2003) J Pharmacol Exp Ther , vol.304 , Issue.1 , pp. 81-87
    • Chalon, S.1
  • 17
    • 1942536500 scopus 로고    scopus 로고
    • Selectivity of (3)H-MADAM binding to 5-hydroxytryptamine transporters in vitro and in vivo in mice; correlation with behavioural effects
    • Larsen A.K., et al. Selectivity of (3)H-MADAM binding to 5-hydroxytryptamine transporters in vitro and in vivo in mice; correlation with behavioural effects. Br J Pharmacol 141 6 (2004) 1015-1023
    • (2004) Br J Pharmacol , vol.141 , Issue.6 , pp. 1015-1023
    • Larsen, A.K.1
  • 18
    • 27744488922 scopus 로고    scopus 로고
    • Quantification of 11C-MADAM binding to the serotonin transporter in the human brain
    • Lundberg J., et al. Quantification of 11C-MADAM binding to the serotonin transporter in the human brain. J Nucl Med 46 9 (2005) 1505-1515
    • (2005) J Nucl Med , vol.46 , Issue.9 , pp. 1505-1515
    • Lundberg, J.1
  • 19
    • 26644455497 scopus 로고    scopus 로고
    • [(11)C]MADAM, a new serotonin transporter radioligand characterized in the monkey brain by PET
    • Halldin C., et al. [(11)C]MADAM, a new serotonin transporter radioligand characterized in the monkey brain by PET. Synapse 58 3 (2005) 173-183
    • (2005) Synapse , vol.58 , Issue.3 , pp. 173-183
    • Halldin, C.1
  • 20
    • 0023186425 scopus 로고
    • Selective labeling of serotonin uptake sites in rat brain by [3H]citalopram contrasted to labeling of multiple sites by [3H]imipramine
    • D'Amato R.J., et al. Selective labeling of serotonin uptake sites in rat brain by [3H]citalopram contrasted to labeling of multiple sites by [3H]imipramine. J Pharmacol Exp Ther 242 1 (1987) 364-371
    • (1987) J Pharmacol Exp Ther , vol.242 , Issue.1 , pp. 364-371
    • D'Amato, R.J.1
  • 21
    • 0025918672 scopus 로고
    • [3H]paroxetine binding and serotonin content of rat and rabbit cortical areas, hippocampus, neostriatum, ventral mesencephalic tegmentum, and midbrain raphe nuclei region
    • Dewar K.M., et al. [3H]paroxetine binding and serotonin content of rat and rabbit cortical areas, hippocampus, neostriatum, ventral mesencephalic tegmentum, and midbrain raphe nuclei region. Synapse 9 1 (1991) 14-26
    • (1991) Synapse , vol.9 , Issue.1 , pp. 14-26
    • Dewar, K.M.1
  • 22
    • 0026610622 scopus 로고
    • [3H]paroxetine binding and serotonin content of rat cortical areas, hippocampus, neostriatum, ventral mesencephalic tegmentum, and midbrain raphe nuclei region following p-chlorophenylalanine and p-chloroamphetamine treatment
    • Dewar K.M., et al. [3H]paroxetine binding and serotonin content of rat cortical areas, hippocampus, neostriatum, ventral mesencephalic tegmentum, and midbrain raphe nuclei region following p-chlorophenylalanine and p-chloroamphetamine treatment. J Neurochem 58 1 (1992) 250-257
    • (1992) J Neurochem , vol.58 , Issue.1 , pp. 250-257
    • Dewar, K.M.1
  • 23
    • 0028063106 scopus 로고
    • Validation of the transporter ligand cyanoimipramine as a marker of serotonin innervation density in brain
    • Soucy J.P., et al. Validation of the transporter ligand cyanoimipramine as a marker of serotonin innervation density in brain. J Nucl Med 35 11 (1994) 1822-1830
    • (1994) J Nucl Med , vol.35 , Issue.11 , pp. 1822-1830
    • Soucy, J.P.1
  • 24
    • 0026539075 scopus 로고
    • The pharmacological effect of citalopram residues in the (S)-(+)- enantiomer
    • Hyttel J., et al. The pharmacological effect of citalopram residues in the (S)-(+)- enantiomer. J Neural Transm Gen Sect 88 2 (1992) 157-160
    • (1992) J Neural Transm Gen Sect , vol.88 , Issue.2 , pp. 157-160
    • Hyttel, J.1
  • 25
    • 0000164769 scopus 로고    scopus 로고
    • The antidepressant effects of citalopram are mediated by the S-(+)- and not the R-(-)-enantiomer
    • Hogg S., and Sanchez C. The antidepressant effects of citalopram are mediated by the S-(+)- and not the R-(-)-enantiomer. Eur Neuropsychopharmacol 9 Suppl 1 (1999) S213
    • (1999) Eur Neuropsychopharmacol , vol.9 , Issue.SUPPL. 1
    • Hogg, S.1    Sanchez, C.2
  • 26
    • 3142756613 scopus 로고    scopus 로고
    • Escitalopram versus citalopram: the surprising role of the R-enantiomer
    • Sanchez C., et al. Escitalopram versus citalopram: the surprising role of the R-enantiomer. Psychopharmacology (Berl) 174 2 (2004) 163-176
    • (2004) Psychopharmacology (Berl) , vol.174 , Issue.2 , pp. 163-176
    • Sanchez, C.1
  • 27
    • 13244262698 scopus 로고    scopus 로고
    • The S-enantiomer of R,S-citalopram, increases inhibitor binding to the human serotonin transporter by an allosteric mechanism. Comparison with other serotonin transporter inhibitors
    • Chen F., et al. The S-enantiomer of R,S-citalopram, increases inhibitor binding to the human serotonin transporter by an allosteric mechanism. Comparison with other serotonin transporter inhibitors. Eur Neuropsychopharmacol 15 2 (2005) 193-198
    • (2005) Eur Neuropsychopharmacol , vol.15 , Issue.2 , pp. 193-198
    • Chen, F.1
  • 28
    • 13244283466 scopus 로고    scopus 로고
    • Characterization of an allosteric citalopram-binding site at the serotonin transporter
    • Chen F., et al. Characterization of an allosteric citalopram-binding site at the serotonin transporter. J Neurochem 92 1 (2005) 21-28
    • (2005) J Neurochem , vol.92 , Issue.1 , pp. 21-28
    • Chen, F.1
  • 29
    • 20444413791 scopus 로고    scopus 로고
    • High- and low-affinity binding of S-citalopram to the human serotonin transporter mutated at 20 putatively important amino acid positions
    • Plenge P., and Wiborg O. High- and low-affinity binding of S-citalopram to the human serotonin transporter mutated at 20 putatively important amino acid positions. Neurosci Lett 383 3 (2005) 203-208
    • (2005) Neurosci Lett , vol.383 , Issue.3 , pp. 203-208
    • Plenge, P.1    Wiborg, O.2
  • 30
    • 33644856545 scopus 로고    scopus 로고
    • Tyr-95 and ile-172 in transmembrane segments 1 and 3 of human serotonin transporters interact to establish high affinity recognition of antidepressants
    • Henry L.K., et al. Tyr-95 and ile-172 in transmembrane segments 1 and 3 of human serotonin transporters interact to establish high affinity recognition of antidepressants. J Biol Chem 281 4 (2006) 2012-2023
    • (2006) J Biol Chem , vol.281 , Issue.4 , pp. 2012-2023
    • Henry, L.K.1
  • 31
    • 0032588744 scopus 로고    scopus 로고
    • Distribution of [3H]citalopram binding sites in the nonhuman primate brain
    • Smith H.R., et al. Distribution of [3H]citalopram binding sites in the nonhuman primate brain. Ann NY Acad Sci 877 (1999) 700-702
    • (1999) Ann NY Acad Sci , vol.877 , pp. 700-702
    • Smith, H.R.1
  • 32
    • 3042776615 scopus 로고    scopus 로고
    • Autoradiographic distribution of serotonin transporters and receptor subtypes in human brain
    • Varnas K., Halldin C., and Hall H. Autoradiographic distribution of serotonin transporters and receptor subtypes in human brain. Hum Brain Mapp 22 3 (2004) 246-260
    • (2004) Hum Brain Mapp , vol.22 , Issue.3 , pp. 246-260
    • Varnas, K.1    Halldin, C.2    Hall, H.3
  • 33
    • 0035910939 scopus 로고    scopus 로고
    • Cloning of dopamine, norepinephrine and serotonin transporters from monkey brain: relevance to cocaine sensitivity
    • Miller G.M., et al. Cloning of dopamine, norepinephrine and serotonin transporters from monkey brain: relevance to cocaine sensitivity. Brain Res Mol Brain Res 87 1 (2001) 124-143
    • (2001) Brain Res Mol Brain Res , vol.87 , Issue.1 , pp. 124-143
    • Miller, G.M.1
  • 34
    • 0026947242 scopus 로고
    • Evaluation of S-[11C]citalopram as a radioligand for in vivo labelling of 5-hydroxytryptamine uptake sites
    • Hume S.P., et al. Evaluation of S-[11C]citalopram as a radioligand for in vivo labelling of 5-hydroxytryptamine uptake sites. Int J Radiat Appl Instrum B Nucl Med Biol 19 8 (1992) 851-855
    • (1992) Int J Radiat Appl Instrum B Nucl Med Biol , vol.19 , Issue.8 , pp. 851-855
    • Hume, S.P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.