-
1
-
-
0037395780
-
The role of genomics in antimicrobial discovery
-
Mills, S. D. 2003. The role of genomics in antimicrobial discovery. J. Antimicrob. Chemother: 51: 749-752.
-
(2003)
J. Antimicrob. Chemother
, vol.51
, pp. 749-752
-
-
Mills, S.D.1
-
2
-
-
10044239624
-
A novel genomics approach for the identification of drug targets in pathogens, with special reference to Pseudomonas aeruginosa
-
Sakharkar, K. R., M. K. Sakharkar, and V. T. K. Chow. 2004. A novel genomics approach for the identification of drug targets in pathogens, with special reference to Pseudomonas aeruginosa. In Silico Biol. 4: 355-360.
-
(2004)
Silico Biol.
, vol.4
, pp. 355-360
-
-
Sakharkar, K.R.1
Sakharkar, M.K.2
Chow, V.T.K.3
-
3
-
-
0036078078
-
Essential genes are more evolutionarily conserved than are nonessential genes in bacteria
-
Jordan, I. K., I. B. Rogozin, Y. I. Wolf, and E. V. Koonin. 2002. Essential genes are more evolutionarily conserved than are nonessential genes in bacteria. Genome Res. 12: 962-968.
-
(2002)
Genome Res.
, vol.12
, pp. 962-968
-
-
Jordan, I.K.1
Rogozin, I.B.2
Wolf, Y.I.3
Koonin, E.V.4
-
4
-
-
4444333240
-
Major Fe-superoxide dimutase (FeSOD) activity in Pseudomonas putida is essential for survival under conditions of oxidative stress during microbial challenge and nutrient limitation
-
Kim, Y. C., C. S. Kim, B. H. Cho, and A. J. Anderson. 2004. Major Fe-superoxide dimutase (FeSOD) activity in Pseudomonas putida is essential for survival under conditions of oxidative stress during microbial challenge and nutrient limitation. J. Microbiol. Biotechnol. 14: 859-862.
-
(2004)
J. Microbiol. Biotechnol.
, vol.14
, pp. 859-862
-
-
Kim, Y.C.1
Kim, C.S.2
Cho, B.H.3
Anderson, A.J.4
-
5
-
-
0345668475
-
Essential Bacillus subtilis genes
-
Kobayashi, K., S. D. Ehrlich, A. Albertini, G. Amati, K. K. Andersen, M. Arnaud, K. Asai, S. Ashikaga, S. Aymerich, P. Bessieres, F. Boland, S. C. Brignell, S. Bron, K. Bunai, J. Chapuis, L. C. Christiansen, A. Danchin, M. Debarbouille, E. Dervyn, E. Deuerling, K. Devine, S. K. Devine, O. Dreesen, J. Errington, S. Fillinger, S. J. Foster, Y. Fujita, A. Galizzi, R. Gardan, C. Eschevins, T. Fukushima, K. Haga, C. R. Harwood, M. Hecker, D. Hosoya, M. F. Hullo, H. Kakeshita, D. Karamata, Y. Kasahara, F. Kawamura, K. Koga, P. Koski, R. Kuwana, D. Imamura, M. Ishimaru, S. Ishikawa, I. Ishio, D. Le Coq, A. Masson, C. Mauel, R. Meima, R. P. Mellado, A. Moir, S. Moriya, E. Nagakawa, H. Nanamiya, S. Nakai, P. Nygaard, M. Ogura, T. Ohanan, M. O'Reilly, M. O'Rourke, Z. Pragai, H. M. Pooley, G. Rapoport, J. P. Rawlins, L. A. Rivas, C. Rivolta, A. Sadaie, Y. Sadaie, M. Sarvas, T. Sato, H. H. Saxild, E. Scanlan, W. Schumann, J. F. Seegers, J. Sekiguchi, A. Sekowska, S. J. Seror, M. Simon, P. Stragier, R. Studer, H. Takamatsu, T. Tanaka, M. Takeuchi, H. B. Thomaides, V. Vagner, J. M. van Dijl, K. Watabe, A. Wipat, H. Yamamoto, M. Yamamoto, Y. Yamamoto, K. Yamane, K. Yata, K. Yoshida, H. Yoshikawa, U. Zuber, and N. Ogasawara. 2003. Essential Bacillus subtilis genes. Proc. Natl. Acad. Sci. USA 100: 4678-4683.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 4678-4683
-
-
Kobayashi, K.1
Ehrlich, S.D.2
Albertini, A.3
Amati, G.4
Andersen, K.K.5
Arnaud, M.6
Asai, K.7
Ashikaga, S.8
Aymerich, S.9
Bessieres, P.10
Boland, F.11
Brignell, S.C.12
Bron, S.13
Bunai, K.14
Chapuis, J.15
Christiansen, L.C.16
Danchin, A.17
Debarbouil, D.M.18
Dervyn, E.19
Deuerling, E.20
Devine, K.21
Devine, S.K.22
Dreesen, O.23
Errington, J.24
Fillinger, S.25
Foster, J.26
Fujita, Y.27
Galizzi, A.28
Gardan, R.29
Eschevins, C.30
Fukushima, T.31
Haga, K.32
Harwood, C.R.33
Hecker, M.34
Hosoya, D.35
Hullo, M.F.36
Kakeshita, H.37
Karamata, D.38
Kasahara, Y.39
Kawamura, F.40
Koga, K.41
Koski, P.42
Kuwana, R.43
Imamura, D.44
Ishimaru, M.45
Ishikawa, S.46
Ishio, I.47
Le Le Coq, D.48
Masson, A.49
Mauel, C.50
Meima, R.51
Mellado, R.P.52
Moir, A.53
Moriya, S.54
Nagakawa, E.55
Nanamiya, H.56
Nakai, S.57
Nygaard, P.58
Ogura, M.59
Ohanan, T.60
O'Reilly, M.61
O'Rourke, M.62
Pragai, Z.63
Pooley, H.M.64
Rapoport, G.65
Rawlins, J.P.66
Rivas, L.A.67
Rivolta, C.68
Sadaie, A.69
Sadaie, Y.70
Sarvas, M.71
Sato, T.72
Saxild, H.H.73
Scanlan, E.74
Schumann, W.75
Seegers, J.F.76
Sekiguchi, J.77
Sekowska, A.78
Seror, S.J.79
Simon, M.80
Stragier, P.81
Studer, R.82
Takamatsu, H.83
Tanaka, T.84
Takeuchi, M.85
Thomaides, M.B.86
Vagner, V.87
van Dijl, J.M.88
Watabe, K.89
Wipat, A.90
Yama Amamoto, H.91
Yamamoto, M.92
Yamamoto, Y.93
Yamane, K.94
Yata, K.95
Yoshida, K.96
Yoshikawa, H.97
Zuber, U.98
Ogasawara, N.99
more..
-
6
-
-
0031784044
-
A genome-based approach for the identification of essential bacterial genes
-
Arigoni, F., F. Talabot, M. Peitsch, M. D. Degerton, E. Meldrum, E. Allet, R. Fish, T. Jamotte, M. L. Curchod, and H. Loferer. 1998. A genome-based approach for the identification of essential bacterial genes. Nat. Biotechnol. 16: 851-858.
-
(1998)
Nat. Biotechnol.
, vol.16
, pp. 851-858
-
-
Arigoni, F.1
Talabot, F.2
Peitsch, M.3
Degerton, M.D.4
Meldrum, E.5
Allet, E.6
Fish, R.7
Jamotte, T.8
Curchod, M.L.9
Loferer, H.10
-
8
-
-
0036271625
-
A genome-wide strategy for the identification of essential genes in Staphylococcus aureus
-
Forsyth, R. A., R. J. Haselbeck, K. L. Ohlsen, R. T. Yamamoto, H. Xu, J. d. Trawick, D. Wall, L. Wang, V. Brown-Driver, J. M. Froelich, P. King, M. McCarthy, C. Malone, B. Misiner, D. Robbins, Z. Tan, Z. Y. Zhu, G. Carr, D. A. Mosca, C. Zamudio, J. G. Foulkes, and J. W. Zyskind. 2002. A genome-wide strategy for the identification of essential genes in Staphylococcus aureus. Mol. Microbiol. 43: 1387-1400.
-
(2002)
Mol. Microbiol.
, vol.43
, pp. 1387-1400
-
-
Forsyth, R.A.1
Haselbeck, R.J.2
Ohlsen, K.L.3
Yamamoto, R.T.4
Xu, H.5
Trawick, J.D.6
Wall, D.7
Wang, L.8
Brown-Driver, V.9
Froelich, J.M.10
King, P.11
McCarthy, M.12
Malone, C.13
Misiner, B.14
Robbins, D.15
Tan, Z.16
Zhu, Z.Y.17
Carr, G.18
Mosca, D.A.19
Zamudio, C.20
Foulkes, J.G.21
Zyskind, J.W.22
more..
-
9
-
-
0035929121
-
Identification of critical staphylococcal genes using conditional phenotypes generated by antisense RNA
-
Ji, Y., B. Zhang, S. F. Van Horn, P. Warren, G. Woodnutt, M. K. R. Burnham, and M. Rosenberg. 2001. Identification of critical staphylococcal genes using conditional phenotypes generated by antisense RNA. Science 293: 2266-2269.
-
(2001)
Science
, vol.293
, pp. 2266-2269
-
-
Ji, Y.1
Zhang, B.2
Van Horn, S.F.3
Warren, P.4
Woodnutt, G.5
Burnham, M.K.R.6
Rosenberg, M.7
-
10
-
-
27944510200
-
Synergistic killing effect of synthetic peptide P20 and cefotaxime on methicillin-resistant nosocomial isolates of Staphylococcus aureus
-
Jung, H. J., K. S. Choi, and D. G. Lee. 2005. Synergistic killing effect of synthetic peptide P20 and cefotaxime on methicillin-resistant nosocomial isolates of Staphylococcus aureus. J. Microbiol. Biotechnol. 15: 1039-1046.
-
(2005)
J. Microbiol. Biotechnol.
, vol.15
, pp. 1039-1046
-
-
Jung, H.J.1
Choi, K.S.2
Lee, D.G.3
-
11
-
-
0035925904
-
Whole genome sequencing of methicillin-resistant Staphylococcus aureus
-
Kuroda, M., T. Ohta, I. Uchiyama, T. Baba, H. Yuzawa, I. Kobayashi, L. Cui, A. Oguchi, K. Aoki, Y. Nagai, J. Lian, T. Ito, M. Kanamori, H. Matsumaru, A. Maruyama, H. Murakami, A. Hosoyama, Y. Mizutani-Ui, N. K. Takahashi, T. Sawano, R. Inoue, C. Kaito, K. Sekimizu, H. Hirakawa, S. Kuhara, S. Goto, J. Yabuzaki, M. Kanehisa, A. Yamashita, K. Oshima, K. Furuya, C. Yoshino, T. Shiba, M. Hattori, N. Ogasawara, H. Hayashi, and K. Hiramatsu. 2001. Whole genome sequencing of methicillin-resistant Staphylococcus aureus. Lancet 357: 1225-1240.
-
(2001)
Lancet
, vol.357
, pp. 1225-1240
-
-
Kuroda, M.1
Ohta, T.2
Uchiyama, I.3
Baba, T.4
Yuzawa, H.5
Kobayashi, I.6
Cui, L.7
Oguchi, A.8
Aoki, K.9
Nagai, Y.10
Lian, J.11
Ito, T.12
Kanamori, M.13
Matsumaru, H.14
Maruyama, A.15
Murakami, H.16
Hosoyama, A.17
Mizutani-Ui, Y.18
Takahashi, N.K.19
Sawano, T.20
Inoue, R.21
Kaito, C.22
Sekimizu, K.23
Hirakawa, H.24
Kuhara, S.25
Goto, S.26
Yabuzaki, J.27
Kanehisa, M.28
Yamashita, A.29
Oshima, K.30
Furuya, K.31
Yoshino, C.32
Shiba, T.33
Hattori, M.34
Ogasawara, N.35
Hayashi, H.36
Hiramatsu, K.37
more..
-
12
-
-
27244451533
-
Identification of essential genes in Streptococcus pneumoniae using allelic replacement mutagenesis
-
Song, J.-H., K. S. Ko, J.-Y. Lee, J. Y. Baek, W. S. Oh, H. S. Yoon, J.-Y. Jeong, and J. Chun. 2005. Identification of essential genes in Streptococcus pneumoniae using allelic replacement mutagenesis. Mol. Cells 19: 365-374.
-
(2005)
Mol. Cells
, vol.19
, pp. 365-374
-
-
Song, J.-H.1
Ko, K.S.2
Lee, J.-Y.3
Baek, J.Y.4
Oh, W.S.5
Yoon, H.S.6
Jeong, J.-Y.7
Chun, J.8
-
13
-
-
33646555924
-
Profiling pyocins and competitive growth advantages of various Pseudomonas aeruginosa strains
-
Heo, Y.-J., K. S. Ko, J.-H. Song, and Y.-H. Cho. 2005. Profiling pyocins and competitive growth advantages of various Pseudomonas aeruginosa strains. J. Microbiol. Biotechnol. 15: 1368-1376.
-
(2005)
J. Microbiol. Biotechnol.
, vol.15
, pp. 1368-1376
-
-
Heo, Y.-J.1
Ko, K.S.2
Song, J.-H.3
Cho, Y.-H.4
-
14
-
-
0029187253
-
Electrotransformation of Staphylococci
-
Nickoloff, J. A. (ed.), Humana Press, Totowa, NJ
-
Lee J. C. 1995. Electrotransformation of Staphylococci, p. 209. In Nickoloff, J. A. (ed.), Methods in Molecular Biology, 47. Humana Press, Totowa, NJ.
-
(1995)
Methods in Molecular Biology
, vol.47
, pp. 209
-
-
Lee, J.C.1
-
15
-
-
0018287541
-
High frequency transformation of Bacillus subtilis protoplasts by plasmid DNA
-
Chang, S. and S. H. Cohen. 1979. High frequency transformation of Bacillus subtilis protoplasts by plasmid DNA. Mol. Gen. Genet. 168: 111-115.
-
(1979)
Mol. Gen. Genet.
, vol.168
, pp. 111-115
-
-
Chang, S.1
Cohen, S.H.2
-
16
-
-
0037100683
-
Identification of 113 conserved essential genes using a high-throughput gene disruption system in Streptococcus pneumoniae
-
Thanassi, J. A., S. L. Hartman-Neumann, T. J. Dougherty, B. A. Dougherty, and M. J. Pucci. 2002. Identification of 113 conserved essential genes using a high-throughput gene disruption system in Streptococcus pneumoniae. Nucleic Acids Res. 30: 3152-3162.
-
(2002)
Nucleic Acids Res.
, vol.30
, pp. 3152-3162
-
-
Thanassi, J.A.1
Hartman-Neumann, S.L.2
Dougherty, T.J.3
Dougherty, B.A.4
Pucci, M.J.5
-
17
-
-
0037154255
-
A genome-scale analysis for identification of genes required for growth or survival of Haemophilus influenzae
-
Akerley, B. J., E. J. Rubin, V. L. Novick, K. Amaya, N. Judson, and J. J. Mekalanos. 2002. A genome-scale analysis for identification of genes required for growth or survival of Haemophilus influenzae. Proc. Natl. Acad. Sci. USA 99: 966-971.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 966-971
-
-
Akerley, B.J.1
Rubin, E.J.2
Novick, V.L.3
Amaya, K.4
Judson, N.5
Mekalanos, J.J.6
-
18
-
-
0032764518
-
Global transposon mutagenesis and a minimal Mycoplasma genome
-
Hutchison, C. A., S. N. Pterson, S. R. Gill, R. T. Cline, O. White, C. M. Fraser, H. O. Smith, and J. C. Venter. 1999. Global transposon mutagenesis and a minimal Mycoplasma genome. Science 286: 2165-2169.
-
(1999)
Science
, vol.286
, pp. 2165-2169
-
-
Hutchison, C.A.1
Pterson, S.N.2
Gill, S.R.3
Cline, R.T.4
White, O.5
Fraser, C.M.6
Smith, H.O.7
Venter, J.C.8
-
19
-
-
0035143428
-
Systematic identification of selective essential genes in Helicobacter pylori by genome prioritization and allelic replacement mutagenesis
-
Chalker, A. F., H. W. Minehart, N. J. Hughes, K. K. Koretke, M. A. Lonetto, K. K. Brinkman, P. V. Warren, A. Lupas, M. J. Stanhope, J. R. Brown, and P. S. Hoffman. 2001. Systematic identification of selective essential genes in Helicobacter pylori by genome prioritization and allelic replacement mutagenesis. J. Bacteriol. 183: 1259-1268.
-
(2001)
J. Bacteriol.
, vol.183
, pp. 1259-1268
-
-
Chalker, A.F.1
Minehart, H.W.2
Hughes, N.J.3
Koretke, K.K.4
Lonetto, M.A.5
Brinkman, K.K.6
Warren, P.V.7
Lupas, A.8
Stanhope, M.J.9
Brown, J.R.10
Hoffman, P.S.11
-
20
-
-
0035940515
-
Comprehensive identification of conditionally essential genes in mycobacteria
-
Sassetti, C. M., D. H. Boyd, and E. J. Rubin. 2001. Comprehensive identification of conditionally essential genes in mycobacteria. Proc. Natl. Acad. Sci. USA 98: 12712-12717.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 12712-12717
-
-
Sassetti, C.M.1
Boyd, D.H.2
Rubin, E.J.3
-
21
-
-
3242795072
-
Engineering recombinant Streptomyces coelicolor malate synthase with improved thermal properties by directed mutagensis
-
Koh, R., L.-L. Goh, and T.-S. Sim. 2004. Engineering recombinant Streptomyces coelicolor malate synthase with improved thermal properties by directed mutagensis. J. Microbiol. Biotechnol. 14: 547-552.
-
(2004)
J. Microbiol. Biotechnol.
, vol.14
, pp. 547-552
-
-
Koh, R.1
Goh, L.-L.2
Sim, T.-S.3
-
23
-
-
12144291286
-
A global approach to identify novel broad-spectrum antibacterial targets among proteins of unknown function
-
Zalacain, M., S. Biswas, K. A. Ingraham, J. Ambrad, A. Bryant, A. F. Chalker, S. Iordanescu, J. Fan, F. Fan, R. D. Lunsford, K. O'Dwyer, L. M. Palmer, C. So, D. Sylvester, C. Volker, P. Warren, D. McDevitt, J. R. Brown, D. J. Holmes, and M. K. Burnham. 2004. A global approach to identify novel broad-spectrum antibacterial targets among proteins of unknown function. J. Mol. Microbiol. Biotechnol. 6: 109-126.
-
(2004)
J. Mol. Microbiol. Biotechnol.
, vol.6
, pp. 109-126
-
-
Zalacain, M.1
Biswas, S.2
Ingraham, K.A.3
Ambrad, J.4
Bryant, A.5
Chalker, A.F.6
Iordanescu, S.7
Fan, J.8
Fan, F.9
Lunsford, R.D.10
O'Dwyer, K.11
Palmer, L.M.12
So, C.13
Sylvester, D.14
Volker, C.15
Warren, P.16
McDevitt, D.17
Brown, J.R.18
Holmes, D.J.19
Burnham, M.K.20
more..
-
24
-
-
0030660581
-
A genomic perspective on protein families
-
Tatusov, R. L., E. V. Koonin, and D. J. Lipman. 1997. A genomic perspective on protein families. Science 278: 631-637.
-
(1997)
Science
, vol.278
, pp. 631-637
-
-
Tatusov, R.L.1
Koonin, E.V.2
Lipman, D.J.3
-
25
-
-
0347915666
-
Transcriptional regulation of the Staphylococcus aureus thioredoxin and thioredoxin reductase genes in response to oxygen and disulfide stress
-
Uziel, O., I. Borovok, R. Schreiber, G. Cohen, and Y. Aharonowitz. 2004. Transcriptional regulation of the Staphylococcus aureus thioredoxin and thioredoxin reductase genes in response to oxygen and disulfide stress. J. Bacteriol. 186: 326-334.
-
(2004)
J. Bacteriol.
, vol.186
, pp. 326-334
-
-
Uziel, O.1
Borovok, I.2
Schreiber, R.3
Cohen, G.4
Aharonowitz, Y.5
-
26
-
-
0035081426
-
Essential role for cellular phosphoglucomutase in virulence of type 3 Streptococcus pneumoniae
-
Hardy, G. G., A. D. Magee, C. L. Ventura, M. J. Caimano, and J. Yother. 2001. Essential role for cellular phosphoglucomutase in virulence of type 3 Streptococcus pneumoniae. Infect. Immun. 69: 2309-2317.
-
(2001)
Infect. Immun.
, vol.69
, pp. 2309-2317
-
-
Hardy, G.G.1
Magee, A.D.2
Ventura, C.L.3
Caimano, M.J.4
Yother, J.5
-
27
-
-
0030055855
-
A phosphoglucomutase-like gene essential for the optimal expression of methicilloin resistance in Staphylococcus aureus: Molecular cloning and DNA sequencing
-
Wu, S., H. de Lencastre, A. Sali, and A. Tomasz. 1996. A phosphoglucomutase-like gene essential for the optimal expression of methicilloin resistance in Staphylococcus aureus: Molecular cloning and DNA sequencing. Microb. Drug Resist. 2: 277-286.
-
(1996)
Microb. Drug Resist.
, vol.2
, pp. 277-286
-
-
Wu, S.1
de Lencastre, H.2
Sali, A.3
Tomasz, A.4
-
29
-
-
21844435978
-
0-ATP synthase of Mycobacterium smegmatis is essential for growth
-
0-ATP synthase of Mycobacterium smegmatis is essential for growth. J. Bacteriol. 187: 5023-5028.
-
(2005)
J. Bacteriol.
, vol.187
, pp. 5023-5028
-
-
Tran, S.L.1
Cook, G.M.2
|