Proteomic analysis of MCF-7 cell lines expressing the zinc-finger or the proline-rich domain of retinoblastoma-interacting-zinc-finger protein

Journal of Proteome Research

Volumn 5, Issue 5, 2006, Pages 1176-1185

  Chambery, Angela ^a   Farina, Annarita ^a   Di Maro, Antimo ^a   Rossi, Mariangela ^a   Abbondanza, Ciro ^a   Moncharmont, Bruno ^c   Malorni, Livia ^b   Cacace, Giuseppina ^b   Pocsfalvi, Gabriella ^b   Malorni, Antonio ^b   Parente, Augusto ^a  

^a SECOND UNIVERSITY OF NAPLES   (Italy)

^b CNR   (Italy)

^c UNIVERSITY OF MOLISE   (Italy)

Author keywords

Mass spectrometry; Peptide mass fingerprint; Proteomics; RIZ domain; Two dimensional gel electrophoresis

Indexed keywords

ALPHA ENOLASE; CATHEPSIN D; DESMUSLIN; GENE PRODUCT; HEAT SHOCK PROTEIN 27; KERATIN; NUCLEOSIDE DIPHOSPHATE KINASE A; PROLINE; PROTEIN DISULFIDE ISOMERASE; RETINOBLASTOMA INTERACTING ZINC FINGER PROTEIN; RNA; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; BREAST CANCER; CELL DIFFERENTIATION; CELL GROWTH; CELL PROLIFERATION; CELL STRAIN MCF 7; CONTROLLED STUDY; CYTOSKELETON; ENERGY METABOLISM; HUMAN; HUMAN CELL; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEOMICS; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; RNA METABOLISM; TWO DIMENSIONAL GEL ELECTROPHORESIS;

BREAST NEOPLASMS; CATHEPSIN D; CELL LINE, TUMOR; CYTOSKELETON; DNA-BINDING PROTEINS; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; ENERGY METABOLISM; FEMALE; HUMANS; NUCLEAR PROTEINS; PHOSPHOPYRUVATE HYDRATASE; PROTEIN ISOFORMS; PROTEIN STRUCTURE, TERTIARY; PROTEOMICS; RNA; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TRANSCRIPTION FACTORS; TUMOR MARKERS, BIOLOGICAL; TUMOR SUPPRESSOR PROTEINS;

EID: 33646562489     PISSN: 15353893     EISSN: None     Source Type: Journal    
DOI: 10.1021/pr0504743     Document Type: Article

References (71)

1. Liu, L.; Shao, G.; Steele-Perkins, G.; Huang, S. The retinoblastoma interacting zinc finger gene RIZ produces a PR domain-lacking product through an internal promoter. J. Biol. Chem. 1997, 272, 2984-2991.
2. Chadwick, R. B.; Jiang, G. L.; Bennington, G. A.; Yuan, B.; Johnson, C. K.; Stevens, M. W.; et al. Candidate tumor suppressor RIZ is frequently involved in colorectal carcinogenesis. Proc. Nat'l Acad. Sci. U.S.A. 2000, 97, 2662-2667.
3. Piao, Z.; Fang, W.; Malkhosyan, S.; Kim, H.; Horii, A.; Perucho, M.; Huang, S. Frequent frameshift mutations of RIZ in sporadic gastrointestinal and endometrial carcinomas with microsatellite instability. Cancer Res. 2000, 60, 4701-4704.
4. Huang, S. The retinoblastoma protein-interacting zinc finger gene RIZ in 1p36-linked cancers. Front. Biosci. 1999, 4, D528-D532.
5. Buyse, I. M.; Huang, S. In vitro analysis of the E1A homologous sequences of RIZ. J. Virol. 1997, 71, 6200-6203.
6. Abbondanza, C., Medici, N., et al. The retinoblastoma interacting zinc finger protein RIZ is a downstream effector of estrogen action. Proc. Nat'l Acad. Sci., U.S.A. 2000, 97 (7), 3130-3135.
7. Rossi, M.; Abbondanza, C.; D'Arcangelo, A.; Gazzerro, P.; Medici, N.; Moncharmont, B.; Puca, G. A. The Zn-finger domain of RIZ protein promotes MCF-7 cell proliferation. Cancer Lett. 2004, 215 (2), 229-237.
8. ImageMaster 2D Elite v3.1 manual, Nonlinear Dynamics.
9. Mayeda, A.; Zahler, A. M.; Krainer, A. R.; Roth, M. B. Two members of a conserved family of nuclear phosphoproteins are involved in pre-mRNA splicing. Proc. Nat'l Acad. Sci., U.S.A. 1992, 89 (4), 1301-1304.
10. Carting, T.; Kim, K.-C.; Yang, X.-H.; Gu, J.; Zhang, X.-K.; Huang, S. A Histone Methyltransferase Is Required for Maximal Response to Female Sex Hormones Mol. Cell. Biol. 2004, 24 (16), 7032-7042.
11. Gazzerro, P.; Abbondanza, C.; D'Arcangelo, A.; Rossi, M.; Medici, N.; Moncharmont, B.; Puca, G. A. Modulation of RIZ gene expression is associated to estradiol control of MCF-7 breast cancer cell proliferation. Exp. Cell Res. 2006, 312(3), 340-349.
12. Trask, D. K.; Band, V.; Zajchowski, D. A.; Yaswen, P.; Sun, T.; Sager, R. Keratins as markers that distinguish normal and tumor-derived mammary epithelial cells. Proc. Nat'l Acad. Sci., U.S.A. 1990, 87(6), 2319-2323.
13. Giometti, C. S.; Tollaksen, S. L.; Chubb, C.; Williams, C.; Huberman, E. Analysis of proteins from human breast epithelial cells using two-dimensional gel electrophoresis Electrophoresis 1995, 16, 1215-1224.
14. Oh, J. M.; Brichory, F.; Puravs, E.; Kuick, R.; Wood, C.; Rouillard, J. M.; Tra, J.; Kardia, S.; Beer, D.; Hanash, S. A database of protein expression in lung cancer. Proteomics 2001, 1, 1303-1319.
15. Hanash, S.; Brichory, F.; Beer, D. A proteomic approach to the identification of lung cancer markers. Dis. Markers 2001, 17, 295-300.
16. Pancholi V. Multifunctional alpha-enolase: its role in diseases. Cell. Mol. Life Sci. 2001, 53 (7), 902-920.
17. Jeffery, C. J. Moonlighting proteins. Trends Biochem. Sci. 1999, 24, 8-11.
18. Seow, T. K.; Ong, S. E.; Liang, R. C.; Ren, E. C.; Chan, L.; Ou, K.; et al. Two-dimensional electrophoresis map of the human hepatocellular carcinoma cell line, HCC-M, and identification of the separated proteins by mass spectrometry. Electrophoresis 2000, 21 (9), 1787-1813.
19. Feo, S.; Arcuri, D.; Piddini, E.; Passantino, R.; Giallongo, A. ENO1 gene product binds to the c-myc promoter and acts as a transcriptional repressor: relationship with Myc promoter-binding protein 1 (MBP-1). FEBS Lett. 2000, 473 (1), 47-52.
20. Subramanian, A.; Miller, D. M. Structural analysis of alpha-enolase. Mapping the functional domains involved in down-regulation of the c-myc protooncogene. J. Biol. Chem. 2000, 275 (8), 5958-5965.
21. Warburg, O. On the origin of cancer cells. Science 1956, 123, 309-314.
22. Wang, T.; Marquardt, C.; Foker, J. Aerobic glycolysis during lymphocyte proliferation. Nature 1976, 261, 702-705.
23. Schwaller, M.; Wilkinson, B.; Gilbert, H. F. Reduction-reoxidation cycles contribute to catalysis of disulfide isomerisation by protein-disulflde isomerase. J. Biol. Chem. 2003, 278, 7154-7159.
24. Freedman, R. B.; Happa, P.; Ruddock, L. W. Catalytic and binding domains in the mechanism and specificty of protein disulphide isomerases: a theme with variations. EMBO Rep. 2002, 3, 136-140.
25. Ferrari, D. M.; Söling, H. D. The protein disulphide-isomerase family: unraveling a string of folds. Biochem. J. 1999, 339, 1-10.
26. Ellgaard, L.; Ruddock, L. W. The human protein disulphide isomerase family: substrate interactions and functional properties. EMBO Rep. 2005, 6 (1), 28-32.
27. Zapun, A.; Darby, N. J.; Tessier, D. C.; Michalak, M.; Bergeron, J. J. M.; Thomas, D. Y.; Enhanced catalysis of ribonuclease B folding by the interaction of calnexin or calreticulin with Erp57. J. Biol. Chem. 1998, 273, 6009-6012.
28. Oliver, J. D.; van der Wal, F. J.; Bulleid, N. J.; High, S. Interaction of the thioldependent reductase ERp57 with nascent glycoproteins. Science 1997, 275, 86-88.
29. Turano, C.; Coppari, S.; Allied, F.; Ferraro, A. Proteins of the PDI family: unpredicted non-ER locations and functions. J. Cell Physiol. 2002, 193, 154-163.
30. Cunnea, P. M. et al. ERdj5, an endoplasmic reticulum (ER)-resident protein containing DnaJ and thioredoxin domains, is expressed in secretory cells or following ER stress. J. Biol. Chem. 2003, 278, 1059-1066.
31. Hosoda, A.; Kimata, Y.; Tsuru, A.; Kohno, K. JPD1, a novel endoplasmic reticulum-resident protein containing both a BiP-interacting J-domain and thioredoxin-like motifs. J. Biol. Chem. 2003, 278, 2669-2676.
32. Meunier, L.; Usherwood, Y. K.; Chung, K. T.; Hendershot, L. M. A subset of chaperones and folding enzymes form multiprotein complexes in endoplasmic reticulum to bind nascent proteins. Mol. Biol. Cell 2002, 13, 4456-4469.
33. Nigam, S. K.; Goldberg, A. L.; Ho, S.; Rohde, M. F.; Bush, K. T.; Sherman, M. Y. A set of endoplasmic reticulum proteins possessing properties of molecular chaperones includes Ca(2.)-binding proteins and members of the thioredoxin superfamily. J. Biol. Chem. 1994, 269, 1744-1749.
34. Graven, K. K.; Molvar, C.; Roncarati, J. S.; Mahn, B. D.; Lowrey, S.; Farber, H. W. Identification of protein disulfide isomerase as an endothelial hypoxic stress protein. Am. J. Physiol. Lung Cell Mol. Physiol. 2002, 282, 996-1003.
35. Miyaishi, O.; Kozaki, K.; Iida, K.; Isobe, K.; Hashizume, Y.; Saga, S. Elevated expression of PDI family proteins during differentiation of mouse F9 teratocarcinoma cells. J. Cell Biochem. 1998, 63, 436-445.
36. Hirano, N.; Shibasaki, F.; Sakai, R.; Tanaka, T.; Nishida, J.; Yazaki, Y.; Takenawa, T.; Hiral, H. Molecular cloning of the human glucose-regulated protein ERp57/GRP58, a thiol-dependent reductase. Identification of its secretory form and inducible expression by the oncogenic transformation. Eur. J. Biochem. 1995, 234, 336-342.
37. Gromova, I.; Gromov, P.; Celis, J. E. Identification of true differentially expressed mRNAs in a pair of human bladder transitional cell carcinomas using an improved differential display procedure. Electrophoresis 1999, 20, 241-248.
38. Skrzydlewska, E.; Sulkowska, M.; Koda, M.; Sulkowski, S. Proteolytic-antiproteolytic balance and its regulation in carcinogenesis. World J. Gastroenterol. 2005, 11 (9), 1251-1266.
39. Nomura, T.; Katunuma, N. Involvement of cathepsins in the invasion, metastasis and proliferation of cancer ells. J. Med. Invest. 2005, 52 (1-2), 1-9.
40. Rochefort, H.; Cathepsin D in breast cancer: A tissue marker associated with metastasis. Eur. J. Cancer 1992, 28A, 1780-1783.
41. Capony, F.; Rougeot, C.; Montcourrier, P.; Cavailles, V.; Salazar, G.; Rochefort, H. Increased secretion, altered processing and glycosylation of pro-cathepsin D in human mammary cancer cells. Cancer Res. 1989, 49, 3904-3909.
42. Cavailles, V.; Garcia, M.; Rochefort, H. Regulation of cathepsin D and pS2 gene expression by growth factors in MCF7 human breast cancer cells. Mol. Endocrinol. 1989, 3, 552-558.
43. Rochefort, H.; Cavailles, V.; Augereau, P.; Capony, V.; Augereau, P.; Brizzo, P.; Vingon, F. Overexpression and hormonal regulation of procathepsin D in mammary and endometrial cancer. J. Steroid Biochem. 1989, 34, 177-182.
44. Chabowski, A.; Sulkowska, M.; Sulkowski, S.; Famulski, W.; Skrzydlewska, E.; Kisielewski, W. Immunohistochemical evaluation of cathepsin D expression in colorectal cancer. Folia Histochem. Cytobiol. 2001, 39, 153-154.
45. Rochefort, H.; Garcia, M., Glondu, M.; Laurent, V.; Liaudet, E.; Rey, J. M.; Roger, P. Cathepsin D in breast cancer: Mechanisms and clinical applications, a 1999 overview. Clin. Chim. Acta 2000, 291, 157-170.
46. Oh-e, H.; Tanaka, S.; Kitadai, Y.; Shimamoto, F.; Yoshihara, M.; Haruma, K. Cathepsin D expression as a possible predictor of lymph node metastasis in submucosal colorectal cancer. Eur. J. Cancer 2001, 37, 180-188.
47. Ikeguchi, M.; Fukuda, K.; Oka, S.; Yamaguchi, K.; Hisamitsu, K.; Tsujitani, S.; Sakatanl, T.; Ueda, T.; Kaibara, N. Clinicopathological significance of cathepsin D expression in gastric adenocarcinoma. Oncology 2001, 61, 71-78.
48. Ioachim, E.; Charchanti, A.; Stavropoulos, N.; Athanassiou, E.; Bafa, M.; Agnantis, N. J. Expression of cathepsin D in urothelial carcinoma of the urinary bladder: An immunohistochemical study including correlations with extracellular matrix components, CD44, p53, Rb, c-erbB-2 and the proliferation indices. Anticancer Res. 2002, 22, 3383-3388.
49. Sebzda, T.; Saleh, Y.; Gburek, J.; Andrzejak, R.; Gnus, J.; Siewinski, M.; Grzebieniak, Z. Cathepsin D expression in human colorectal cancer: relationship with tumour type and tissue differentiation grade. J. Exp. Ther. Oncol. 2005, 5(2), 145-150.
50. Bercham, G.; Glondu, M.; Gleizes, M.; Brouillet, J. P.; Vignon, F.; Garcia, M.; Liaudet-Coopman, E. Cathepsin-D affects multiple tumor progression steps in vivo: Proliferation, angiogenesis and apoptosis. Oncogene 2002, 21, 5951-5955.
51. Westley, B.; Rochefort, H. A secreted glycoprotein induced by estrogen in human breast cancer cell lines. Cell 1980, 20, 353-362.
52. Westley, B. R.; May, F. E. Cathepsin D and breast cancer. Eur. J. Cancer 1996, 32A (1), 15-24.
53. Foekens, J. A.; Look, M. P.; Bolt-de Vries, J.; Meijer-van Gelder, M. E.; van Putten, W. L.; Klijn, J. G.; Cathepsin-D in primary breast cancer: prognostic evaluation involving 2810 patients. Brit. J. Cancer. 1999, 79 (2), 300-307.
54. Ferrandina, G.; Scambia, G.; Bardelli, F.; Benedetti Panici, P.; Mancuso, S.; Messori, A. Relationship between cathepsin-D content and disease-free survival in node-negative breast cancer patients: a meta-analysis. Brit. J. Cancer. 1997, 76 (5), 661-666.
55. Gendler, S. J.; Dermer, G. B.; Silverman, L. M.; Tokes, Z. A. Synthesis of alpha 1-antichymotrypsin and alpha 1-acid glycoprotein by human breast epithelial cells. Cancer Res. 1982, 42 (11), 4567-4573.
56. Mercatante, D.; Kole, R. Modification of alternative splicing pathways as a potential approach to chemotherapy. Pharmacol. Ther. 2000, 85, 237-243.
57. Dreyfuss, G.; Kim, V. N.; Kataoka, N. Messenger-RNA-binding proteins and the messages they carry. Nat. Rev. Mol. Cell Biol. 2002, 3, 195-205.
58. Black, D. L. Mechanisms of alternative pre-messenger RNA splicing. Annu. Rev. Biochem. 2003, 72, 291-336.
59. Wang, Z. N.; Lo, H. S.; Yang, H.; et al. Computational analysis and experimental validation of tumor-associated alternative RNA splicing in human cancer. Cancer Res. 2003, 63, 655-657.
60. Stickeler, E.; Kittrell, F.; Medina, D.; Berget, S. M. Stagespecific changes in SR splicing factors and alternative splicing in mammary tumorigenesis. Oncogene 1999, 18, 3574-3582.
61. Zerbe, L. K.; Pino, I.; Pio, R.; Cosper, P. F.; Dwyer-Nield, L. D.; Meyer, A. M.; Port, J. D.; Montuenga, L. M.; Malkinson, A. M. Relative amounts of antagonistic splicing factors, hnRNP A1 and ASF/SF2, change during neoplastic lung growth: implications for pre-mRNA processing. Mol. Carcinogen. 2004, 41 (4), 187-196.
62. Cao, W.; Jamison, S. F.; Garcia-Blanco, M. A. Both phosphorylation and dephosphorylation of ASF/SF2 are required for pre-mRNA splicing in vitro. RNA 1997, 3, 1456-1467.
63. Xiao, S. H.; Manley, J. L. Phosphorylation-dephosphorylation differentially affects activities of splicing factor ASF/SF2. EMBO J. 1998, 17, 6359-6367.
64. Prasad, J.; Colwill, K.; Pawson, T.; Manley, J. L. The protein kinase Clk/Sty directly modulates SR protein activity: Both hyper- and hypophosphorylation inhibit splicing. Mol. Cell. Biol. 1999, 19, 6991-7000.
65. Utz, P. J.; Hottelet, M.; van Venrooij, W. J.; Anderson, P. Association of phosphorylated serine/arginine (SR) splicing factors with the U1-small ribonucleoprotein (snRNP) autoantigen complex accompanies apoptotic cell death. J. Exp. Med. 1998, 187, 547-560.
66. Ghigna, C.; Giordano, S.; Shen, H.; Benvenuto, F.; Castiglioni, F.; Comoglio, P. M.; Green, M. R.; Riva, S.; Biamonti, G. Cell motility is controlled by SF2/ASF through alternative splicing of the Ron protooncogene. Mol. Cell. 2005, 20 (6), 881-890.
67. Longman, D.; Johnstone, I. L; Caceres, J. F. Functional characterization of SR and SR-related genes in Caenorhabditis elegans. EMBO J. 2000, 19, 1625-1637.
68. Stierum, R.; Gaspari, M.; Dommels, Y.; Ouatas, T.; Pluk, H.; Jespersen, S.; Vogels, J.; Verhoeckx, K.; Groten, J.; van Ommen, B. Proteome analysis reveals novel proteins associated with proliferation and differentiation of the colorectal cancer cell line Caco-2. Biochim. Biophys. Acta. 2003, 1650 (1-2), 73-91.
69. Cipollini, G.; Berti, A.; Fiore, L.; Rainaldi, G.; Basolo, F.; Merlo, G. et al. Down-regulation of the nm23.h1 gene inhibits cell proliferation. Int. J. Cancer 1997, 73 (2), 297-302.
70. Caligo, M. A.; Cipollini, G.; Petrini, M.; Valentini, P.; Bevilacqua, G. Down regulation of NM23.H1, NM23.H2 and c-myc genes during differentiation induced by 1, 25 dihydroxyvitamin D3. Leuk. Res. 1996, 20 (2), 161-167.
71. Olsen, E.; Rasmussen, H. H.; Cells, J. E. Identification of proteins that are abnormally regulated in differentiated cultured human keratinocytes. Electrophoresis 1995, 16 (12), 2241-2248.