ADME related profiling in 96 and 384 well plate format - A novel and robust HT-assay for the determination of lipophilicity and serum albumin binding

Current Drug Delivery

Volumn 3, Issue 2, 2006, Pages 181-192

  Hartmann, Thorsten ^a   Schmitt, Johannes ^a   Röhring, Cornelia ^a   Nimptsch, Daniel ^a   Nöller, Joachim ^a   Mohr, Christoph ^a  

^a NIMBUS Biotechnologie GmbH   (Germany)

Author keywords

384 well plates; 96 well plates; ADME; High throughput; Lipophilicity; Prediction; Serum protein binding

Indexed keywords

ALBUMIN; BETAXOLOL; CAFFEINE; CAPTOPRIL; CEFALEXIN; CHLORPROMAZINE; CLOMIPRAMINE; CLOZAPINE; DILTIAZEM; DOXORUBICIN; ENALAPRIL; FUROSEMIDE; GUANABENZ; HALOPERIDOL; HYDROCORTISONE BUTYRATE; IMIPRAMINE; LISINOPRIL; METHYLPREDNISOLONE; METOLAZONE; ONDANSETRON; PINDOLOL; PIROXICAM; PREDNISOLONE; PROGESTERONE; PROMAZINE; PROPRANOLOL; QUINIDINE; SCOPOLAMINE; SOTALOL; UNINDEXED DRUG;

ACCELERATION; ALBUMIN BLOOD LEVEL; ARTICLE; DRUG DETERMINATION; DRUG SOLUBILITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIPID COMPOSITION; LIPOPHILICITY; ORGAN DISTRIBUTION; PLASMA PROTEIN BINDING; PRIORITY JOURNAL; REPRODUCIBILITY;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; LIPID BILAYERS; MASS SPECTROMETRY; PHARMACEUTICAL PREPARATIONS; PROTEIN BINDING; REPRODUCIBILITY OF RESULTS; SERUM ALBUMIN; SOLUBILITY;

EID: 33646558303     PISSN: 15672018     EISSN: None     Source Type: Journal    
DOI: 10.2174/156720106776359177     Document Type: Article

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