Increased macrophage inflammatory protein-1α and macrophage inflammatory protein-1β levels in bronchoalveolar lavage fluid of patients affected by different stages of pulmonary sarcoidosis

American Journal of Respiratory and Critical Care Medicine

Volumn 165, Issue 2, 2002, Pages 236-241

  Capelli, Armando ^a,b   Stefano, Antonino D I ^a   Lusuardi, Mirco ^a   Gnemmi, Isabella ^a   Donner, Claudio F ^a  

^a IRCCS   (Italy)

^b Centro Medico di Riabilitazione   (Italy)

Author keywords

Bronchoalveolar lavage; CCR5; Macrophage inflammatory protein 1 ; Macrophage inflammatory protein 1 ; Sarcoidosis

Indexed keywords

BETA CHEMOKINE; CHEMOKINE RECEPTOR CCR5; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA;

ADULT; AGED; ARTICLE; CHEMOTAXIS; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; LUNG ALVEOLUS MACROPHAGE; LUNG SARCOIDOSIS; LYMPHOCYTE; LYMPHOCYTE MIGRATION; MALE; NEUTROPHIL; PRIORITY JOURNAL;

EID: 0037080753     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.165.2.2106084     Document Type: Article

References (30)

1. Statement on Sarcoidosis
2. Pulmonary sarcoidosis: A disorder mediated by excess helper T-lymphocyte activity at sites of disease activity
3. CD8 alveolitis in sarcoidosis: Incidence, phenotypic characteristics, and clinical features
4. Spontaneous expression of the interleukin 2 receptor gene and presence of functional interleukin 2 receptors on T lymphocytes in the blood of individuals with active pulmonary sarcoidosis
5. Gamma interferon is spontaneously released by alveolar macrophages and lung T lymphocytes in patients with pulmonary sarcoidosis
6. Enhanced expression of IL-12 associated with Th1 cytokine profiles in active pulmonary sarcoidosis
7. Role of IL-15, IL-2, and their receptors in the development of T cell alveolitis in pulmonary sarcoidosis
8. Sarcoidosis: Immunopathogenetic concepts and their clinical application
9. C-C chemokine: Novel mediators of the profibrotic inflammatory response to bleomycin challenge
10. Preferential migration of activated CD4+ and CDS+ T cells in response to MIP-1 alpha and M1P-1 beta
11. Interaction of chemokine receptor CCR5 with its ligands: Multiple domains for HIV-1 gp 120 binding and a single domain for chemokine binding
12. CCR5 is characteristic of Th1 lymphocytes
13. The roentgenographic staging of sarcoidosis
14. Acid phosphatase (E.C. 3.1.3.2.) activity in alveolar macrophages from patients with active sarcoidosis
15. Pulmonary sarcoidosis: Alteration in bronchoalveolar lymphocytes and T cell subsets
16. Prognostic value of bronchoalveolar lavage in sarcoidosis: The critical influence of disease presentation
17. Th1 cytokine pattern in sarcoidosis is expressed by bronchoalveolar CD4+ and CD8+ T cells
18. T cell independence of bleomycin-induced pulmonary fibrosis
19. Synthesis of the CC-chemokines MIP-1alpha, MIP-1beta, and RANTES is associated with the type 1 immune response
20. Increased expression of proinflammatory chemokines in bronchoalveolar lavage cells of patients with progressing idiopathic pulmonary fibrosis and sarcoidosis
21. Production and function of murine macrophage inflammatory protein-1α bleomycin-induced lung injury
22. Hyaluronan (HA) fragments induce chemokine gene expression in alveolar macrophages
23. Identification of RANTES, MIP-1α, and MIP-1β as the major HIV-suppressive factors produced by CD8+ T cell
24. Elevated chemokine levels in bronchoalveolar lavage fluid of patients with eosinophilic pneumonia
25. Role of CC chemokines (macrophages inflammatory protein-1β, monocyte chemoattractant protein-1, RANTES) in acute lung injury in rats
26. CC Chemokine receptor gene polymorphisms in Czech patients with pulmonary sarcoidosis
27. The chemokine system: Redundancy for robust outputs
28. Th1 and Th2 responses regulate experimental lung granuloma development
29. Downregulation of CCR5 receptor expression in lymphocytes and alveolar macrophages of smokers with chronic obstructive pulmonary disease (COPD)
30. Cleavage of lymphocyte surface antigens CD2, CD4, CD8 by polymorphonuclear leukocyte elastase and cathepsin G in patients with cystic fibrosis