Expression of a dominant negative SHP-2 in transgenic mice induces insulin resistance

Journal of Biological Chemistry

Volumn 274, Issue 42, 1999, Pages 30236-30243

  Maegawa, Hiroshi ^a   Hasegawa, Masaaki ^a   Sugai, Satoshi ^b   Obata, Toshiyuki ^a   Ugi, Satoshi ^a   Morino, Katsutaro ^a   Egawa, Katsuya ^a   Fujita, Toshiki ^a   Sakamoto, Takahiko ^b   Nishio, Yoshihiko ^a   Kojima, Hideto ^a   Haneda, Masakazu ^a   Yasuda, Hitoshi ^a   Kikkawa, Ryuichi ^a   Kashiwagi, Atsunori ^a  

^a SHIGA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

^b ONO PHARMACEUTICAL CO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPOSE TISSUE; ANIMAL CELL; ARTICLE; DROSOPHILA MELANOGASTER; ENZYME INDUCTION; ENZYME SUBSTRATE; GENE EXPRESSION REGULATION; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; INSULIN RESISTANCE; INSULIN SENSITIVITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN;

ANIMALS; ENZYME ACTIVATION; GENES, DOMINANT; GLUCOSE; GLYCOGEN SYNTHASE; INSULIN; INSULIN RESISTANCE; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MICE; MICE, TRANSGENIC; MITOGEN-ACTIVATED PROTEIN KINASES; MUSCLE, SKELETAL; PROTEIN-TYROSINE-PHOSPHATASE; SHP1 PROTEIN TYROSINE PHOSPHATASE; SIGNAL TRANSDUCTION;

ANIMALIA; DROSOPHILA MELANOGASTER; MELANOGASTER; MUS MUSCULUS; RODENTIA;

EID: 0033570225     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.42.30236     Document Type: Article

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