Tetrabutylammonium fluoride-mediated rapid alkylation reaction in microtiter plates for the discovery of enzyme inhibitors in situ

ChemBioChem

Volumn 6, Issue 12, 2005, Pages 2176-2180

  Wu, Chung Yi ^a,b   Brik, Ashraf ^a   Wang, Sheng Kai ^a   Chen, Yu Hsien ^a   Wong, Chi Huey ^a,b  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b GENOMICS RESEARCH CENTER   (Taiwan)

Author keywords

Alkylation; Chemistry esterification; Combinatorial; Inhibitors; TBAF

Indexed keywords

AMINE; ARYL SULFOTRANSFERASE; BENZOIC ACID; BENZOTRIAZOLE DERIVATIVE; CARBOXYLASE; CARBOXYLIC ACID DERIVATIVE; CASPASE 3; CATHEPSIN B; ENZYME INHIBITOR; ESTER DERIVATIVE; FLUORIDE; HALIDE; ISATIN DERIVATIVE; NITROGEN; NUCLEOSIDE; PROTEINASE; PURINE DERIVATIVE; QUINIC ACID; SHIKIMIC ACID; SULFONAMIDE; TETRABUTYLAMMONIUM; TRIAZOLE DERIVATIVE; CARBOXYLIC ACID; QUATERNARY AMMONIUM DERIVATIVE; SOLVENT;

ALKYLATION; AQUEOUS SOLUTION; ARTICLE; CATALYSIS; CHEMICAL STRUCTURE; ESTERIFICATION; MICROTITER PLATE ASSAY; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN TARGETING; STOICHIOMETRY; SYNTHESIS; CHEMISTRY; DRUG SCREENING; METHODOLOGY; MICROARRAY ANALYSIS;

ALKYLATION; AMINES; CARBOXYLIC ACIDS; DRUG EVALUATION, PRECLINICAL; ENZYME INHIBITORS; MICROARRAY ANALYSIS; QUATERNARY AMMONIUM COMPOUNDS; SOLVENTS; SULFONAMIDES; TRIAZOLES;

EID: 33646529851     PISSN: 14394227     EISSN: 14397633     Source Type: Journal    
DOI: 10.1002/cbic.200500295     Document Type: Article

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