Selective terminal heck arylation of vinyl ethers with aryl chlorides: A combined experimental-computational approach including synthesis of betaxolol

Journal of Organic Chemistry

Volumn 71, Issue 10, 2006, Pages 3896-3903

  Datta, Gopal K ^a   Von Schenck, Henrik ^a   Hallberg, Anders ^a   Larhed, Mats ^a  

^a UPPSALA UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ARYL CHLORIDES; ARYLATION; BETAXOLOL; VINYL ETHERS;

CATALYSIS; CHLORINE COMPOUNDS; COMPUTATIONAL METHODS; PALLADIUM; PHENOLS; REACTION KINETICS; STEREOCHEMISTRY; SYNTHESIS (CHEMICAL);

ETHERS;

4 [2 (CYCLOPROPYLMETHOXY)ETHYL]PHENOL; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BETAXOLOL; CHLORIDE DERIVATIVE; CHLORNITROFEN; ETHER DERIVATIVE; MACROGOL 200; N,N DIMETHYLFORMAMIDE; PALLADIUM COMPLEX; POLYCYCLIC AROMATIC HYDROCARBON DERIVATIVE; UNCLASSIFIED DRUG; VINYL DERIVATIVE;

ARTICLE; ARYLATION; BETA ADRENERGIC RECEPTOR BLOCKING; CATALYSIS; CHEMICAL REACTION KINETICS; DENSITY FUNCTIONAL THEORY; DRUG SYNTHESIS; ELECTRON TRANSPORT; HEATING; HECK REACTION; MATHEMATICAL COMPUTING; MICROWAVE RADIATION; PROCESS OPTIMIZATION; STEREOCHEMISTRY;

BETAXOLOL; CHLORIDES; COMBINATORIAL CHEMISTRY TECHNIQUES; MODELS, MOLECULAR; MOLECULAR STRUCTURE; VINYL COMPOUNDS;

EID: 33646498748     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo0602367     Document Type: Article

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