-
1
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D, Weinberg RA: The hallmarks of cancer. Cell 100(1):57-70, 2000
-
(2000)
Cell
, vol.100
, Issue.1
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
2
-
-
0031466305
-
Cyclin-dependent kinases: Engines, clocks, and microprocessors
-
Morgan DO: Cyclin-dependent kinases: Engines, clocks, and microprocessors. Annu Rev Cell Dev Biol 13:261-291, 1997
-
(1997)
Annu Rev Cell Dev Biol
, vol.13
, pp. 261-291
-
-
Morgan, D.O.1
-
3
-
-
0034887884
-
Cell cycle-mediated drug resistance: An emerging concept in cancer therapy
-
Shah MA, Schwartz GK: Cell cycle-mediated drug resistance: An emerging concept in cancer therapy. Clin Cancer Res 7(8):2168-2181, 2001
-
(2001)
Clin Cancer Res
, vol.7
, Issue.8
, pp. 2168-2181
-
-
Shah, M.A.1
Schwartz, G.K.2
-
4
-
-
0034162636
-
Preclinical and clinical development of cyclin-dependent kinase modulators
-
Senderowicz AM, Sausville EA: Preclinical and clinical development of cyclin-dependent kinase modulators. J Natl Cancer Inst 92(5):376-387, 2000
-
(2000)
J Natl Cancer Inst
, vol.92
, Issue.5
, pp. 376-387
-
-
Senderowicz, A.M.1
Sausville, E.A.2
-
5
-
-
0035055595
-
Mechanisms of action of flavopiridol
-
Sedlacek HH: Mechanisms of action of flavopiridol. Crit Rev Oncol Hematol 38(2):139-170, 2001
-
(2001)
Crit Rev Oncol Hematol
, vol.38
, Issue.2
, pp. 139-170
-
-
Sedlacek, H.H.1
-
6
-
-
0033568521
-
Down-regulation of cyclin D1 by transcriptional repression in MCF-7 human breast carcinoma cells induced by flavopiridol
-
Carlson B, Lahusen T, Singh S, Loaiza-Perez A, Worland PJ, Pestell R, Albanese C, Sausville EA, Senderowicz: Down-regulation of cyclin D1 by transcriptional repression in MCF-7 human breast carcinoma cells induced by flavopiridol. Cancer Res 59(18):4634-4641, 1999
-
(1999)
Cancer Res
, vol.59
, Issue.18
, pp. 4634-4641
-
-
Carlson, B.1
Lahusen, T.2
Singh, S.3
Loaiza-Perez, A.4
Worland, P.J.5
Pestell, R.6
Albanese, C.7
Sausville, E.A.8
Senderowicz9
-
7
-
-
0033960068
-
Induction of apoptosis and inhibition of c-erbB-2 in breast cancer cells by flavopiridol
-
Li Y, Bhuiyan M, Alhasan S, Senderowicz AM, Sarkar FH: Induction of apoptosis and inhibition of c-erbB-2 in breast cancer cells by flavopiridol. Clin Cancer Res 6(1):223-229, 2000
-
(2000)
Clin Cancer Res
, vol.6
, Issue.1
, pp. 223-229
-
-
Li, Y.1
Bhuiyan, M.2
Alhasan, S.3
Senderowicz, A.M.4
Sarkar, F.H.5
-
8
-
-
0029665778
-
Flavopiridol induces G1 arrest with inhibition of cyclin-dependent kinase (CDK) 2 and CDK4 in human breast carcinoma cells
-
Carlson BA, Dubay MM, Sausville EA, Brizuela L, Worland PJ: Flavopiridol induces G1 arrest with inhibition of cyclin-dependent kinase (CDK) 2 and CDK4 in human breast carcinoma cells. Cancer Res 56(13):2973-2978, 1996
-
(1996)
Cancer Res
, vol.56
, Issue.13
, pp. 2973-2978
-
-
Carlson, B.A.1
Dubay, M.M.2
Sausville, E.A.3
Brizuela, L.4
Worland, P.J.5
-
9
-
-
0348075994
-
Flavopiridol enhances the effects of docetaxel in vitro and in vivo in human gastric cancer cells
-
Motwani M, Rizzo C, Sirotnak F, She Y, Schwartz GK: Flavopiridol enhances the effects of docetaxel in vitro and in vivo in human gastric cancer cells. Mol Cancer Ther 2(6):549-555, 2003
-
(2003)
Mol Cancer Ther
, vol.2
, Issue.6
, pp. 549-555
-
-
Motwani, M.1
Rizzo, C.2
Sirotnak, F.3
She, Y.4
Schwartz, G.K.5
-
10
-
-
0032804733
-
Sequential dependent enhancement of caspase activation and apoptosis by flavopiridol on paclitaxel-treated human gastric and breast cancer cells
-
Motwani M, Delohery TM, Schwartz GK: Sequential dependent enhancement of caspase activation and apoptosis by flavopiridol on paclitaxel-treated human gastric and breast cancer cells. Clin Cancer Res 5(7):1876-1883, 1999
-
(1999)
Clin Cancer Res
, vol.5
, Issue.7
, pp. 1876-1883
-
-
Motwani, M.1
Delohery, T.M.2
Schwartz, G.K.3
-
11
-
-
0031670668
-
Phase I trial of continuous infusion flavopiridol, a novel cyclin-dependent kinase inhibitor, in patients with refractory neoplasms
-
Senderowicz AM, Headlee D, Stinson SF, Lush RM, Kalil N, Villalba L, Hill K, Steinberg SM, Figg WD, Tompkins A, Arbuck SG, Sausville EA: Phase I trial of continuous infusion flavopiridol, a novel cyclin-dependent kinase inhibitor, in patients with refractory neoplasms. J Clin Oncol 16(9):2986-2999, 1998
-
(1998)
J Clin Oncol
, vol.16
, Issue.9
, pp. 2986-2999
-
-
Senderowicz, A.M.1
Headlee, D.2
Stinson, S.F.3
Lush, R.M.4
Kalil, N.5
Villalba, L.6
Hill, K.7
Steinberg, S.M.8
Figg, W.D.9
Tompkins, A.10
Arbuck, S.G.11
Sausville, E.A.12
-
12
-
-
0036450831
-
Phase I clinical and pharmacokinetic trial of the cyclin-dependent kinase inhibitor flavopiridol
-
Thomas JP, Tutsch KD, Cleary JF, Bailey HH, Arzoomanian R, Alberti D, Simon K, Feierabend C, Binger K, Marnocha R, Dresen A, Wilding G : Phase I clinical and pharmacokinetic trial of the cyclin-dependent kinase inhibitor flavopiridol. Cancer Chemother Pharmacol 50(6):465-472, 2002
-
(2002)
Cancer Chemother Pharmacol
, vol.50
, Issue.6
, pp. 465-472
-
-
Thomas, J.P.1
Tutsch, K.D.2
Cleary, J.F.3
Bailey, H.H.4
Arzoomanian, R.5
Alberti, D.6
Simon, K.7
Feierabend, C.8
Binger, K.9
Marnocha, R.10
Dresen, A.11
Wilding, G.12
-
13
-
-
0037089691
-
Phase I study of the cyclin-dependent kinase inhibitor flavopiridol in combination with paclitaxel in patients with advanced solid tumors. J
-
Schwartz GK, O'Reilly E, Ilson D, Saltz L, Sharma S, Tong W, Maslak P, Stoltz M, Eden L, Perkins P, Endres S, Barazzoul J, Spriggs D, Kelsen D: Phase I study of the cyclin-dependent kinase inhibitor flavopiridol in combination with paclitaxel in patients with advanced solid tumors. J Clin Oncol 20(8):2157-2170, 2002
-
(2002)
Clin Oncol
, vol.20
, Issue.8
, pp. 2157-2170
-
-
Schwartz, G.K.1
O'Reilly, E.2
Ilson, D.3
Saltz, L.4
Sharma, S.5
Tong, W.6
Maslak, P.7
Stoltz, M.8
Eden, L.9
Perkins, P.10
Endres, S.11
Barazzoul, J.12
Spriggs, D.13
Kelsen, D.14
-
14
-
-
0029100273
-
Taxanes: A new class of antitumor agents
-
Huizing MT, Misser VH, Pieters RC, ten Bokkel Huinink WW, Veenhof CH, Vermorken JB, Pinedo HM, Beijnen JH: Taxanes: A new class of antitumor agents. Cancer Invest 13(4):381-404, 1995
-
(1995)
Cancer Invest
, vol.13
, Issue.4
, pp. 381-404
-
-
Huizing, M.T.1
Misser, V.H.2
Pieters, R.C.3
Ten Bokkel Huinink, W.W.4
Veenhof, C.H.5
Vermorken, J.B.6
Pinedo, H.M.7
Beijnen, J.H.8
-
15
-
-
0037430246
-
Comparison of antiangiogenic activities using paclitaxel (taxol) and docetaxel (taxotere)
-
Grant DS, Williams TL, Zahaczewsky M, Dicker AP: Comparison of antiangiogenic activities using paclitaxel (taxol) and docetaxel (taxotere). Int J Cancer 104(1):121-129, 2003
-
(2003)
Int J Cancer
, vol.104
, Issue.1
, pp. 121-129
-
-
Grant, D.S.1
Williams, T.L.2
Zahaczewsky, M.3
Dicker, A.P.4
-
16
-
-
0035026002
-
Docetaxel: Overview of an active drug for breast cancer
-
Crown J: Docetaxel: Overview of an active drug for breast cancer. Oncologist 6(Suppl 3):1-4, 2001
-
(2001)
Oncologist
, vol.6
, Issue.3 SUPPL.
, pp. 1-4
-
-
Crown, J.1
-
18
-
-
0033047742
-
Rapid and sensitive determination of paclitaxel in mouse plasma by high-performance liquid chromatography
-
Lee SH, Yoo SD, Lee KH: Rapid and sensitive determination of paclitaxel in mouse plasma by high-performance liquid chromatography. J Chromatogr B Biomed Sci Appl 724(2):357-363, 1999
-
(1999)
J Chromatogr B Biomed Sci Appl
, vol.724
, Issue.2
, pp. 357-363
-
-
Lee, S.H.1
Yoo, S.D.2
Lee, K.H.3
-
19
-
-
0035300684
-
Phase II study of the cyclin-dependent kinase inhibitor flavopiridol administered to patients with advanced gastric carcinoma
-
Schwartz GK, Ilson D, Saltz L, O'Reilly E, Tong W, Maslak P, Werner J, Perkins P, Stoltz M, Kelsen D: Phase II study of the cyclin-dependent kinase inhibitor flavopiridol administered to patients with advanced gastric carcinoma. J Clin Oncol 19(7): 1985-1992, 2001
-
(2001)
J Clin Oncol
, vol.19
, Issue.7
, pp. 1985-1992
-
-
Schwartz, G.K.1
Ilson, D.2
Saltz, L.3
O'Reilly, E.4
Tong, W.5
Maslak, P.6
Werner, J.7
Perkins, P.8
Stoltz, M.9
Kelsen, D.10
-
20
-
-
0033955395
-
Flavopiridol, a novel cyclin-dependent kinase inhibitor, in metastatic renal cancer: A University of Chicago Phase II Consortium study
-
Stadler WM, Vogelzang NJ, Amato R, Sosman J, Taber D, Liebowitz D, Vokes EE: Flavopiridol, a novel cyclin-dependent kinase inhibitor, in metastatic renal cancer: A University of Chicago Phase II Consortium study. J Clin Oncol 18(2):371-375, 2000
-
(2000)
J Clin Oncol
, vol.18
, Issue.2
, pp. 371-375
-
-
Stadler, W.M.1
Vogelzang, N.J.2
Amato, R.3
Sosman, J.4
Taber, D.5
Liebowitz, D.6
Vokes, E.E.7
-
21
-
-
0034900178
-
A phase II trial of the cyclin-dependent kinase inhibitor flavopiridol in patients with previously untreated stage IV non-small cell lung cancer
-
Shapiro GI, Supko JG, Patterson A, A phase II trial of the cyclin-dependent kinase inhibitor flavopiridol in patients with previously untreated stage IV non-small cell lung cancer. Clin Cancer Res 7(6):1590-1599, 2001
-
(2001)
Clin Cancer Res
, vol.7
, Issue.6
, pp. 1590-1599
-
-
Shapiro, G.I.1
Supko, J.G.2
Patterson, A.3
-
22
-
-
0033034008
-
Clinical pharmackokinetics of docetaxel
-
Clarke SJ, Rivory LP: Clinical pharmackokinetics of docetaxel. Clin Pharmacokinetics 36(2):99-114, 1999
-
(1999)
Clin Pharmacokinetics
, vol.36
, Issue.2
, pp. 99-114
-
-
Clarke, S.J.1
Rivory, L.P.2
-
23
-
-
0027516128
-
Phase I and pharmacokinetic study of Taxotere (RP 56976; NSC 628503) given as a short intravenous infusion
-
Extra JM, Rousseau F, Bruno R, Clavel M, Le Bail N, Marty M: Phase I and pharmacokinetic study of Taxotere (RP 56976; NSC 628503) given as a short intravenous infusion. Cancer Res 53(5):1037-1042, 1993
-
(1993)
Cancer Res
, vol.53
, Issue.5
, pp. 1037-1042
-
-
Extra, J.M.1
Rousseau, F.2
Bruno, R.3
Clavel, M.4
Le Bail, N.5
Marty, M.6
-
24
-
-
0033974846
-
Pharmacokinetics and metabolism of docetaxel administered as a 1-h intravenous infusion
-
Rosing H, Lustig V, van Warmerdam LJ, Huizing MT, ten Bokkel Huinink WW, Schellens JH, Rodenhuis S, Bult A, Beijnene JH: Pharmacokinetics and metabolism of docetaxel administered as a 1-h intravenous infusion. Cancer Chemother Pharmacol 45(3):213-218, 2000
-
(2000)
Cancer Chemother Pharmacol
, vol.45
, Issue.3
, pp. 213-218
-
-
Rosing, H.1
Lustig, V.2
Van Warmerdam, L.J.3
Huizing, M.T.4
Ten Bokkel Huinink, W.W.5
Schellens, J.H.6
Rodenhuis, S.7
Bult, A.8
Beijnene, J.H.9
-
25
-
-
0031471976
-
Pharmacokinetic and pharmacodynamic properties of docetaxel: Results of phase I and phase II trials
-
Bruno R, Riva A, Hille D, Lebecq A, Thomas L: Pharmacokinetic and pharmacodynamic properties of docetaxel: Results of phase I and phase II trials. Am J Health Syst Pharm 54(24 Suppl 2):S16-S19, 1997
-
(1997)
Am J Health Syst Pharm
, vol.54
, Issue.24 SUPPL. 2
-
-
Bruno, R.1
Riva, A.2
Hille, D.3
Lebecq, A.4
Thomas, L.5
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