-
1
-
-
0000391746
-
Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis
-
Bergers G, Brekken R, McMahon G, Vu TH, Itoh T, Tamaki K, Tanzawa K, Thorpe P, Itohara S, Werb Z, Hanahan D. Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis. Nat Cell Biol 2000;10:737-44.
-
(2000)
Nat Cell Biol
, vol.10
, pp. 737-744
-
-
Bergers, G.1
Brekken, R.2
McMahon, G.3
Vu, T.H.4
Itoh, T.5
Tamaki, K.6
Tanzawa, K.7
Thorpe, P.8
Itohara, S.9
Werb, Z.10
Hanahan, D.11
-
2
-
-
0024549349
-
Induction of angiogenesis during the transition from hyperplasia to neoplasia
-
Folkman J, Watson K, Ingber D, Hanahan D. Induction of angiogenesis during the transition from hyperplasia to neoplasia. Nature 1989;6219:58-61.
-
(1989)
Nature
, vol.6219
, pp. 58-61
-
-
Folkman, J.1
Watson, K.2
Ingber, D.3
Hanahan, D.4
-
3
-
-
0033119833
-
Tumor-derived expression of vascular endothelial growth factor is a critical factor in tumor expansion and vascular function
-
Grunstein J, Roberts WG, Mathieu-Costello O, Hanahan D, Johnson RS. Tumor-derived expression of vascular endothelial growth factor is a critical factor in tumor expansion and vascular function. Cancer Res 1999;7:592-8.
-
(1999)
Cancer Res
, vol.7
, pp. 592-598
-
-
Grunstein, J.1
Roberts, W.G.2
Mathieu-Costello, O.3
Hanahan, D.4
Johnson, R.S.5
-
4
-
-
0027479424
-
Genistein arrests cell cycle progression at G2-M
-
Matsukawa Y, Marui N, Sakai T, Satomi Y, Yoshida M, Matsumoto K, Nishino H, Aoike A. Genistein arrests cell cycle progression at G2-M. Cancer Res 1993;53:1328-31.
-
(1993)
Cancer Res
, vol.53
, pp. 1328-1331
-
-
Matsukawa, Y.1
Marui, N.2
Sakai, T.3
Satomi, Y.4
Yoshida, M.5
Matsumoto, K.6
Nishino, H.7
Aoike, A.8
-
5
-
-
0028928687
-
Genistein as an inducer of tumour cell differentiation: Possible mechanisms of action
-
Constantinou A, Huberman E. Genistein as an inducer of tumour cell differentiation: possible mechanisms of action. Proc Soc Exp Biol Med 1995;208:109-115.
-
(1995)
Proc Soc Exp Biol Med
, vol.208
, pp. 109-115
-
-
Constantinou, A.1
Huberman, E.2
-
6
-
-
0025363503
-
Induction of differentiation and DNA strand breakage in human HL-60 and K-562 leukemia cells by genistein
-
Constantinou A, Kiguchi K, Huberman E. Induction of differentiation and DNA strand breakage in human HL-60 and K-562 leukemia cells by genistein. Cancer Res 1990;50:2618-24.
-
(1990)
Cancer Res
, vol.50
, pp. 2618-2624
-
-
Constantinou, A.1
Kiguchi, K.2
Huberman, E.3
-
7
-
-
0026035529
-
Induction of in vitro differentiation of mouse erythroleukemia cells by genistein, an inhibitor of tyrosine protein kinases
-
Watanabe T, Kondo K, Oishi M. Induction of in vitro differentiation of mouse erythroleukemia cells by genistein, an inhibitor of tyrosine protein kinases. Cancer Res 1991;51:764-8.
-
(1991)
Cancer Res
, vol.51
, pp. 764-768
-
-
Watanabe, T.1
Kondo, K.2
Oishi, M.3
-
8
-
-
0028985934
-
Biotherapy of B-cell precursor leukemia by targeting genistein to CD19-associated tyrosine kinases
-
Uckun FM, Evans WE, Forsyth CJ, Waddick KG, Ahlgren LT, Chelstrom LM, Burkhardt A, Bolen J, Myers DE. Biotherapy of B-cell precursor leukemia by targeting genistein to CD19-associated tyrosine kinases. Science 1995;267:886-91.
-
(1995)
Science
, vol.267
, pp. 886-891
-
-
Uckun, F.M.1
Evans, W.E.2
Forsyth, C.J.3
Waddick, K.G.4
Ahlgren, L.T.5
Chelstrom, L.M.6
Burkhardt, A.7
Bolen, J.8
Myers, D.E.9
-
9
-
-
0026471968
-
Effects of genistein on the growth and cell cycle progression of normal human lymphocytes and human leukemic MOLT-4 and HL-60 cells
-
Tragonos F, Ardelt B, Halko N, Bruno S, Darzynkiewicz Z. Effects of genistein on the growth and cell cycle progression of normal human lymphocytes and human leukemic MOLT-4 and HL-60 cells. Cancer Res 1992;52:6200-08.
-
(1992)
Cancer Res
, vol.52
, pp. 6200-6208
-
-
Tragonos, F.1
Ardelt, B.2
Halko, N.3
Bruno, S.4
Darzynkiewicz, Z.5
-
10
-
-
0026044563
-
Genistein inhibition of the growth of human breast cancer cells: Independence from estrogen receptors and the multi-drug resistance gene
-
Peterson G, Barnes S. Genistein inhibition of the growth of human breast cancer cells: independence from estrogen receptors and the multi-drug resistance gene. Biochem Biophys Res Commun 1991;179:661-7.
-
(1991)
Biochem Biophys Res Commun
, vol.179
, pp. 661-667
-
-
Peterson, G.1
Barnes, S.2
-
11
-
-
0028895694
-
Genistein, a dietary ingested isoflavonoid, inhibits cell proliferation and in vitro angiogenesis
-
Fotsis T, Pepper M, Adlercreutz H, Hase T, Montesano R, Schweigerer L. Genistein, a dietary ingested isoflavonoid, inhibits cell proliferation and in vitro angiogenesis. J Nutr 1995;125:790S-797S.
-
(1995)
J Nutr
, vol.125
-
-
Fotsis, T.1
Pepper, M.2
Adlercreutz, H.3
Hase, T.4
Montesano, R.5
Schweigerer, L.6
-
12
-
-
0029961485
-
Genistein-stimulated adherence of prostate cancer cells is associated with the binding of coal adhesion kinase to β-1-integrin
-
Bergan R, Kyle E, Nguyen P, Trepel J, Ingui C, Neckers L. Genistein-stimulated adherence of prostate cancer cells is associated with the binding of coal adhesion kinase to β-1-integrin. Clin Exp Metastasis 1996;14:389-98.
-
(1996)
Clin Exp Metastasis
, vol.14
, pp. 389-398
-
-
Bergan, R.1
Kyle, E.2
Nguyen, P.3
Trepel, J.4
Ingui, C.5
Neckers, L.6
-
13
-
-
0026586723
-
Identification in human urine of a natural growth inhibitor for cells derived from solid paediatric tumours
-
Schweigerer L, Christeleit K, Fleischmann G, Adlercreutz H, Wahala K, Hase T, Schwab M, Ludwig R, Fotsis T. Identification in human urine of a natural growth inhibitor for cells derived from solid paediatric tumours. Fur J Clin Invest 1992;22:260-4.
-
(1992)
Fur J Clin Invest
, vol.22
, pp. 260-264
-
-
Schweigerer, L.1
Christeleit, K.2
Fleischmann, G.3
Adlercreutz, H.4
Wahala, K.5
Hase, T.6
Schwab, M.7
Ludwig, R.8
Fotsis, T.9
-
14
-
-
0037854571
-
Phenoxodiol - An isoflavon analogue-induces apoptosis in chemo-resistant ovarian cancer cells
-
Kamsteeg M, Rutherford T, Sapi E, Hanczaruk B, Shahabi S, Flick M, Brown D, Mor G. Phenoxodiol-an isoflavon analogue-induces apoptosis in chemo-resistant ovarian cancer cells. Oncogene 2003;22:2611-20.
-
(2003)
Oncogene
, vol.22
, pp. 2611-2620
-
-
Kamsteeg, M.1
Rutherford, T.2
Sapi, E.3
Hanczaruk, B.4
Shahabi, S.5
Flick, M.6
Brown, D.7
Mor, G.8
-
15
-
-
0027371722
-
Sphingosine-1-phosphate as second messenger in cell proliferation induced by PDGF and FCS mitogens
-
Olivera A, Spiegel S. Sphingosine-1-phosphate as second messenger in cell proliferation induced by PDGF and FCS mitogens. Nature 1993;365:557-60.
-
(1993)
Nature
, vol.365
, pp. 557-560
-
-
Olivera, A.1
Spiegel, S.2
-
16
-
-
0026049696
-
Sphingosine-1-phosphate, a novel lipid, involved in cellular proliferation
-
Zhang H, Desai NN, Olivera A, Seki T, Brooker G, Spiegel S. Sphingosine-1-phosphate, a novel lipid, involved in cellular proliferation. J Cell Biol 1991;114:155-67.
-
(1991)
J Cell Biol
, vol.114
, pp. 155-167
-
-
Zhang, H.1
Desai, N.N.2
Olivera, A.3
Seki, T.4
Brooker, G.5
Spiegel, S.6
-
17
-
-
17344394207
-
Dual actions of sphingosine-1-phosphate: Extracellular through the Gi-coupled receptor Edg-1 and intracellular to regulate proliferation and survival
-
Van Brocklyn JR, Lee MJ, Menzeleev R, Olivera A, Edsall L, Cuvillier O, Thomas DM, Coopman PJ, Thangada S, Liu CH, Hla T, Spiegel S. Dual actions of sphingosine-1-phosphate: extracellular through the Gi-coupled receptor Edg-1 and intracellular to regulate proliferation and survival. J Cell Biol 1998;142:229-40.
-
(1998)
J Cell Biol
, vol.142
, pp. 229-240
-
-
Van Brocklyn, J.R.1
Lee, M.J.2
Menzeleev, R.3
Olivera, A.4
Edsall, L.5
Cuvillier, O.6
Thomas, D.M.7
Coopman, P.J.8
Thangada, S.9
Liu, C.H.10
Hla, T.11
Spiegel, S.12
-
18
-
-
0033230364
-
Sphingosine kinase expression increases intracellular sphingosine-1-phosphate and promotes cell growth and survival
-
Olivera A, Kohama T, Edsall L, Nava V, Cuvillier O, Poulton S, Spiegel S. Sphingosine kinase expression increases intracellular sphingosine-1-phosphate and promotes cell growth and survival [In Process Citation]. J Cell Biol 1999;147:545-58.
-
(1999)
J Cell Biol
, vol.147
, pp. 545-558
-
-
Olivera, A.1
Kohama, T.2
Edsall, L.3
Nava, V.4
Cuvillier, O.5
Poulton, S.6
Spiegel, S.7
-
19
-
-
0032746381
-
Sphingosine-1-phosphate modulates growth and adhesion of ovarian cancer cells
-
Hong G, Baudhuin LM, Xu Y. Sphingosine-1-phosphate modulates growth and adhesion of ovarian cancer cells. FEBS Lett 1999;460:513-18.
-
(1999)
FEBS Lett
, vol.460
, pp. 513-518
-
-
Hong, G.1
Baudhuin, L.M.2
Xu, Y.3
-
20
-
-
0034735916
-
An oncogenic role of sphingosine kinase
-
Xia P, Gamble JR, Wang L, Pitson SM, Moretti PAB, Wattenberg BW, D'Andrea RJ, Vadas MA. An oncogenic role of sphingosine kinase. Current Biol 2000;10:1527-30.
-
(2000)
Current Biol
, vol.10
, pp. 1527-1530
-
-
Xia, P.1
Gamble, J.R.2
Wang, L.3
Pitson, S.M.4
Moretti, P.A.B.5
Wattenberg, B.W.6
D'Andrea, R.J.7
Vadas, M.A.8
-
21
-
-
0036841720
-
Sphingosine kinase mediates vascular endothelial growth factor-induced activation of ras and mitogen-activated protein kinases
-
Shu X, Wu W, Mosteller RD, Broek D. Sphingosine kinase mediates vascular endothelial growth factor-induced activation of ras and mitogen-activated protein kinases. Mol Cell Biol 2002;22:7758-68.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 7758-7768
-
-
Shu, X.1
Wu, W.2
Mosteller, R.D.3
Broek, D.4
-
22
-
-
0036436697
-
Sphingosine kinase type 1 promotes estrogen-dependent tumorigenesis of breast cancer MCF-7 cells
-
Nava VE, Hobson JP, Murthy S, Milstien S, Spiegel S. Sphingosine kinase type 1 promotes estrogen-dependent tumorigenesis of breast cancer MCF-7 cells. Exp Cell Res 2002;281:115-27.
-
(2002)
Exp Cell Res
, vol.281
, pp. 115-127
-
-
Nava, V.E.1
Hobson, J.P.2
Murthy, S.3
Milstien, S.4
Spiegel, S.5
-
23
-
-
0142056955
-
Sphingosine kinase transmits oestrogen signaling in human breast cancer cells
-
Sukocheva OA, Wang L, Albanese N, Pitson SM, Vadas MA, Xia P. Sphingosine kinase transmits oestrogen signaling in human breast cancer cells. Mol Endocrinol 2003;17:2002-4.
-
(2003)
Mol Endocrinol
, vol.17
, pp. 2002-2004
-
-
Sukocheva, O.A.1
Wang, L.2
Albanese, N.3
Pitson, S.M.4
Vadas, M.A.5
Xia, P.6
-
24
-
-
0141507968
-
Discovery and evaluation of inhibitors of human sphingosine kinase
-
French KJ, Schrecengost RS, Lee BD, Zhuang Y, Smith SN, Eberly JL, Yun JK, Smith CD. Discovery and evaluation of inhibitors of human sphingosine kinase. Cancer Res 2003;63:5962-9.
-
(2003)
Cancer Res
, vol.63
, pp. 5962-5969
-
-
French, K.J.1
Schrecengost, R.S.2
Lee, B.D.3
Zhuang, Y.4
Smith, S.N.5
Eberly, J.L.6
Yun, J.K.7
Smith, C.D.8
-
25
-
-
13144254221
-
Tumour necrosis factor-α induces adhesion molecule expression through the sphingosine kinase pathway
-
Xia P, Gamble JR, Rye K-A, Wang L, Hii CST, Cockerill P, Khew-Goodall Y, Bert AG, Barter PJ, Vadas MA. Tumour necrosis factor-α induces adhesion molecule expression through the sphingosine kinase pathway. Proc Natl Acad Scie USA 1998;95:14196-201.
-
(1998)
Proc Natl Acad Scie USA
, vol.95
, pp. 14196-14201
-
-
Xia, P.1
Gamble, J.R.2
Rye, K.-A.3
Wang, L.4
Hii, C.S.T.5
Cockerill, P.6
Khew-Goodall, Y.7
Bert, A.G.8
Barter, P.J.9
Vadas, M.A.10
-
26
-
-
0033607517
-
Activation of sphingosine kinase by tumour necrosis factor-α inhibits apoptosis in human endothelial cells
-
Xia P, Wang L, Gamble JR, Vadas MA. Activation of sphingosine kinase by tumour necrosis factor-α inhibits apoptosis in human endothelial cells. J Biol Chem 1999;274:34499-505.
-
(1999)
J Biol Chem
, vol.274
, pp. 34499-34505
-
-
Xia, P.1
Wang, L.2
Gamble, J.R.3
Vadas, M.A.4
-
27
-
-
0033517823
-
Sphingosine-1-phosphate induces angiogenesis: Its angiogenic action and signaling mechanism in human umbilical vein endothelial cells
-
Lee OH, Kim YM, Lee YM, Moon EJ, Lee DJ, Kim JH, Kim KW, Kwon YG. Sphingosine-1-phosphate induces angiogenesis: its angiogenic action and signaling mechanism in human umbilical vein endothelial cells. Biochem Biophys Res Commun 1999;264:743-50.
-
(1999)
Biochem Biophys Res Commun
, vol.264
, pp. 743-750
-
-
Lee, O.H.1
Kim, Y.M.2
Lee, Y.M.3
Moon, E.J.4
Lee, D.J.5
Kim, J.H.6
Kim, K.W.7
Kwon, Y.G.8
-
28
-
-
0033452587
-
Induction of endothelial cell chemotaxis by sphingosine 1-phosphate and stabilization of endothelial monolayer barrier function by lysophosphatidic acid, potential mediators of hematopoietic angiogenesis
-
English D, Kovala AT, Welch Z, Harvey KA, Siddiqui RA, Brindley DN, Garcia JG. Induction of endothelial cell chemotaxis by sphingosine 1-phosphate and stabilization of endothelial monolayer barrier function by lysophosphatidic acid, potential mediators of hematopoietic angiogenesis. J Hematother Stem Cell Res 1999;8:627-34.
-
(1999)
J Hematother Stem Cell Res
, vol.8
, pp. 627-634
-
-
English, D.1
Kovala, A.T.2
Welch, Z.3
Harvey, K.A.4
Siddiqui, R.A.5
Brindley, D.N.6
Garcia, J.G.7
-
29
-
-
0037155259
-
Extracellular export of sphingosine kinase-1 enzyme. Sphingosine 1-phosphate generation and the induction of angiogenic vascular maturation
-
Ancellin N, Colmont C, Su J, Li Q, Mittereder N, Chae SS, Stefansson S, Liau G, Hla T. Extracellular export of sphingosine kinase-1 enzyme. Sphingosine 1-phosphate generation and the induction of angiogenic vascular maturation. J Biol Chem 2002;277:6667-75.
-
(2002)
J Biol Chem
, vol.277
, pp. 6667-6675
-
-
Ancellin, N.1
Colmont, C.2
Su, J.3
Li, Q.4
Mittereder, N.5
Chae, S.S.6
Stefansson, S.7
Liau, G.8
Hla, T.9
-
30
-
-
0032723117
-
High density lipoproteins (HDL) interrupt the sphingosine kinase signaling pathway. A possible mechanism for protection against atherosclerosis by HDL
-
Xia P, Vadas MA, Rye KA, Barter PJ, Gamble JR. High density lipoproteins (HDL) interrupt the sphingosine kinase signaling pathway. A possible mechanism for protection against atherosclerosis by HDL. J Biol Chem 1999;274:33143-7.
-
(1999)
J Biol Chem
, vol.274
, pp. 33143-33147
-
-
Xia, P.1
Vadas, M.A.2
Rye, K.A.3
Barter, P.J.4
Gamble, J.R.5
-
31
-
-
0033783522
-
Edg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation
-
Liu Y, Wada R, Yamashita T, Mi Y, Deng C-X, Hobson JP, Rosenfeldt HM, Nava VE, Chae S-K, Lee M-J, Liu CH, Hla T, et al. Edg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation. J Clin Invest 2000;106:951-61.
-
(2000)
J Clin Invest
, vol.106
, pp. 951-961
-
-
Liu, Y.1
Wada, R.2
Yamashita, T.3
Mi, Y.4
Deng, C.-X.5
Hobson, J.P.6
Rosenfeldt, H.M.7
Nava, V.E.8
Chae, S.-K.9
Lee, M.-J.10
Liu, C.H.11
Hla, T.12
-
32
-
-
17044371645
-
Sphingosine kinase-1 enhances endothelial cell survival through a PECAM-1 dependent activation of P13K/Akt and regulation of Bcl-2 family members
-
Limaye V, Li X, Hahn C, Xia P, Berndt MC, Vadas MA, Gamble TR. Sphingosine kinase-1 enhances endothelial cell survival through a PECAM-1 dependent activation of P13K/Akt and regulation of Bcl-2 family members. Blood 2005;105:3169-77.
-
(2005)
Blood
, vol.105
, pp. 3169-3177
-
-
Limaye, V.1
Li, X.2
Hahn, C.3
Xia, P.4
Berndt, M.C.5
Vadas, M.A.6
Gamble, T.R.7
-
33
-
-
0027262209
-
Regulation of in vitro capillary tube formation by anti-integrin antibodies
-
Gamble JR, Matthias LJ, Meyer G, Kaur P, Russ G, Faull R, Berndt MC, Vadas MA. Regulation of in vitro capillary tube formation by anti-integrin antibodies. J Cell Biol 1993;121:931-43.
-
(1993)
J Cell Biol
, vol.121
, pp. 931-943
-
-
Gamble, J.R.1
Matthias, L.J.2
Meyer, G.3
Kaur, P.4
Russ, G.5
Faull, R.6
Berndt, M.C.7
Vadas, M.A.8
-
34
-
-
0027513593
-
Integrin β- and β3-mediated endothelial cell migration is triggered through distinct signaling mechanisms
-
Leavesley DI, Schwartz MA, Rosenfeld M, Cheresh DA. Integrin β- and β3-mediated endothelial cell migration is triggered through distinct signaling mechanisms. J Cell Biol 1993;121:163-70.
-
(1993)
J Cell Biol
, vol.121
, pp. 163-170
-
-
Leavesley, D.I.1
Schwartz, M.A.2
Rosenfeld, M.3
Cheresh, D.A.4
-
35
-
-
0033257007
-
β1 integrin activation inhibits in vitro tube formation: Effects on cell migration, vacuole coalescence and lumen formation
-
Gamble J, Meyer G, Noack L, Furze J, Matthias L, Kovach N, Harlan J, Vadas MA. β1 integrin activation inhibits in vitro tube formation: effects on cell migration, vacuole coalescence and lumen formation. Endothelium 1999;7:23-34.
-
(1999)
Endothelium
, vol.7
, pp. 23-34
-
-
Gamble, J.1
Meyer, G.2
Noack, L.3
Furze, J.4
Matthias, L.5
Kovach, N.6
Harlan, J.7
Vadas, M.A.8
-
37
-
-
0038407310
-
Angiopoietin-1 inhibits vascular permeability, angiogenesis, and growth of hepatic colon cancer tumours
-
Stoeltzing O, Ahmad SA, Liu W, McCarty MF, Wey JS, Parikh AA, Fan F, Reinmuth N, Kawaguchi M, Bucana CD, Ellis LM. Angiopoietin-1 inhibits vascular permeability, angiogenesis, and growth of hepatic colon cancer tumours. Cancer Res 2003;63:3370-7.
-
(2003)
Cancer Res
, vol.63
, pp. 3370-3377
-
-
Stoeltzing, O.1
Ahmad, S.A.2
Liu, W.3
McCarty, M.F.4
Wey, J.S.5
Parikh, A.A.6
Fan, F.7
Reinmuth, N.8
Kawaguchi, M.9
Bucana, C.D.10
Ellis, L.M.11
-
38
-
-
0035576820
-
Inhibition of angiogenesis and metastasis in two murine models by the matrix metalloproteinase inhibitor, BMS-275291
-
Naglich JG, Jure-Kunkel M, Gupta E, Fargnoli J, Henderson AJ, Lewin AC, Talbott R, Baxter A, Bird J, Savopoulos R, Wills R, Kramer RA, et al. Inhibition of angiogenesis and metastasis in two murine models by the matrix metalloproteinase inhibitor, BMS-275291. Cancer Res 2001;61:8480-5.
-
(2001)
Cancer Res
, vol.61
, pp. 8480-8485
-
-
Naglich, J.G.1
Jure-Kunkel, M.2
Gupta, E.3
Fargnoli, J.4
Henderson, A.J.5
Lewin, A.C.6
Talbott, R.7
Baxter, A.8
Bird, J.9
Savopoulos, R.10
Wills, R.11
Kramer, R.A.12
-
39
-
-
0032488895
-
Three-dimensional type I collagen lattices induce coordinate expression of matrix metalloproteinases MT1-MMP and MMP-2 in microvascular endothelial cells
-
Haas TL, Davis SJ, Madri JA. Three-dimensional type I collagen lattices induce coordinate expression of matrix metalloproteinases MT1-MMP and MMP-2 in microvascular endothelial cells. J Biol Chem 1998;273:3604-10.
-
(1998)
J Biol Chem
, vol.273
, pp. 3604-3610
-
-
Haas, T.L.1
Davis, S.J.2
Madri, J.A.3
-
40
-
-
0034635995
-
Matrix metalloproteinase-2 is required for the switch to the angiogenic phenotype in a tumour model
-
Fang J, Shing Y, Wiederschain D, Van L, Butterfield C, Jackson G, Harper J, Tamvakopoulos G, Moses MA. Matrix metalloproteinase-2 is required for the switch to the angiogenic phenotype in a tumour model. Proc Natl Acad Sci USA 2000;97:3884-9.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 3884-3889
-
-
Fang, J.1
Shing, Y.2
Wiederschain, D.3
Van, L.4
Butterfield, C.5
Jackson, G.6
Harper, J.7
Tamvakopoulos, G.8
Moses, M.A.9
-
41
-
-
0036719311
-
Interleukin-1α promotes angiogenesis in vivo via VEGFR-2 pathway by inducing inflammatory cell VEGF synthesis and secretion
-
Salven P, Hattori K, Heissig B, Rafii S. Interleukin-1α promotes angiogenesis in vivo via VEGFR-2 pathway by inducing inflammatory cell VEGF synthesis and secretion. FASEB J 2002;16:1471-3.
-
(2002)
FASEB J
, vol.16
, pp. 1471-1473
-
-
Salven, P.1
Hattori, K.2
Heissig, B.3
Rafii, S.4
-
42
-
-
0036315845
-
α5-β1-integrin activates and NF-κB-dependent program of gene expression important for angiogenesis and inflammation
-
Klein S, de Fougerolles AR, Blaikie P, Khan L, Pepe A, Green CD, Koteliansky V, Giancotti FG. α5-β1-integrin activates and NF-κB-dependent program of gene expression important for angiogenesis and inflammation. Mol Cell Biol 2002;22:5912-22.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 5912-5922
-
-
Klein, S.1
De Fougerolles, A.R.2
Blaikie, P.3
Khan, L.4
Pepe, A.5
Green, C.D.6
Koteliansky, V.7
Giancotti, F.G.8
-
43
-
-
0023664272
-
Genistein, a specific inhibitor of tyrosine-specific protein kinases
-
Akiyama T, Ishida J, Nakagawa S, Ogawara H, Watanabe S, Itoh N, Shibuya M, Fukami Y. Genistein, a specific inhibitor of tyrosine-specific protein kinases. J Biol Chem 1987;262:5592-5.
-
(1987)
J Biol Chem
, vol.262
, pp. 5592-5595
-
-
Akiyama, T.1
Ishida, J.2
Nakagawa, S.3
Ogawara, H.4
Watanabe, S.5
Itoh, N.6
Shibuya, M.7
Fukami, Y.8
-
44
-
-
0028948804
-
Flavonoids as DNA topoisomerase antagonists and poisons: Structure-activity relationships
-
Constantinou A, Mehta R, Runyan C, Rao K, Vaughan A, Moon R. Flavonoids as DNA topoisomerase antagonists and poisons: structure-activity relationships. J Nat Prod 1995;58:217-25.
-
(1995)
J Nat Prod
, vol.58
, pp. 217-225
-
-
Constantinou, A.1
Mehta, R.2
Runyan, C.3
Rao, K.4
Vaughan, A.5
Moon, R.6
-
45
-
-
0024431747
-
Inhibitory effects of the tyrosine kinase inhibitor genistein on mammalian DNA topoisomerase II
-
Markovits J, Linassier C, Fosse P, Couprie J, Pierre J, Jacquemin-Sablon A, Saucier JM, Le Pecq JB, Larsen AK. Inhibitory effects of the tyrosine kinase inhibitor genistein on mammalian DNA topoisomerase II. Cancer Res 1989;49:5111-17.
-
(1989)
Cancer Res
, vol.49
, pp. 5111-5117
-
-
Markovits, J.1
Linassier, C.2
Fosse, P.3
Couprie, J.4
Pierre, J.5
Jacquemin-Sablon, A.6
Saucier, J.M.7
Le Pecq, J.B.8
Larsen, A.K.9
-
46
-
-
0022896243
-
Topoisomerase II: A specific marker for cell proliferation
-
Heck MM, Earnshaw WC. Topoisomerase II: a specific marker for cell proliferation. J Cell Biol 1986;103:2569-81.
-
(1986)
J Cell Biol
, vol.103
, pp. 2569-2581
-
-
Heck, M.M.1
Earnshaw, W.C.2
-
47
-
-
0036765911
-
Phenoxodiol 2H-1-benzopyran-7-0,1,3-(4-hydroxyphenyl), a novel isoflavone derivative, inhibits DNA topoisomerase II by stabilizing the cleavable complex
-
Constantinou AI, Husband A. Phenoxodiol (2H-1-benzopyran-7-0,1,3-(4- hydroxyphenyl), a novel isoflavone derivative, inhibits DNA topoisomerase II by stabilizing the cleavable complex. Anticancer Res 2002;22,2581-5.
-
(2002)
Anticancer Res
, vol.22
, pp. 2581-2585
-
-
Constantinou, A.I.1
Husband, A.2
-
48
-
-
0034662612
-
Sphingosine enhances apoptosis of radiation-resistant prostate cancer cells
-
Nava VE, Cuvillier O, Edsall LC, Kimura K, Milstein S, Gelmann EP, Spiegel S. Sphingosine enhances apoptosis of radiation-resistant prostate cancer cells. Cancer Res 2000;60:4468-74.
-
(2000)
Cancer Res
, vol.60
, pp. 4468-4474
-
-
Nava, V.E.1
Cuvillier, O.2
Edsall, L.C.3
Kimura, K.4
Milstein, S.5
Gelmann, E.P.6
Spiegel, S.7
-
49
-
-
0029948396
-
Suppression of ceramide mediated programme cell death by sphingosine-1-phosphate
-
Cuvillier O, Prianov G, Kleuser B, Vanek PG, Coso O, Gutkind S, Spiegel S. Suppression of ceramide mediated programme cell death by sphingosine-1- phosphate. Nature (London) 1996;381:800-03.
-
(1996)
Nature (London)
, vol.381
, pp. 800-803
-
-
Cuvillier, O.1
Prianov, G.2
Kleuser, B.3
Vanek, P.G.4
Coso, O.5
Gutkind, S.6
Spiegel, S.7
-
50
-
-
0038118495
-
VEGF receptor expression and signaling in human bladder tumors
-
Wu W, Shu X, Hovsepyan H, Mosteller RD, Broek D. VEGF receptor expression and signaling in human bladder tumors. Oncogene 2003;22:3361-70.
-
(2003)
Oncogene
, vol.22
, pp. 3361-3370
-
-
Wu, W.1
Shu, X.2
Hovsepyan, H.3
Mosteller, R.D.4
Broek, D.5
-
51
-
-
0036841720
-
Sphingosine kinase mediates vascular endothelial growth factor-induced activation of ras and mitogen-activated protein kinases
-
Shu X, Wu W, Mosteller RD, Broek D. Sphingosine kinase mediates vascular endothelial growth factor-induced activation of ras and mitogen-activated protein kinases. Mol Cell Biol 2002;22:7758-68.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 7758-7768
-
-
Shu, X.1
Wu, W.2
Mosteller, R.D.3
Broek, D.4
-
52
-
-
0035992417
-
Inhibition of nuclear factor κB activation in PC3 cells by genistein is mediated via Akt signaling pathway
-
Li Y, Sarkar FH. Inhibition of nuclear factor κB activation in PC3 cells by genistein is mediated via Akt signaling pathway. Clin Cancer Res 2002;8:2369-77.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 2369-2377
-
-
Li, Y.1
Sarkar, F.H.2
-
53
-
-
0041589149
-
Inactivation of NF-κB by genistein is mediated via Akt signaling pathway in breast cancer cells
-
Gong L, Nedeljkovic-Kurepa A, Sarkar FH. Inactivation of NF-κB by genistein is mediated via Akt signaling pathway in breast cancer cells. Oncogene 2003;22:4702-9.
-
(2003)
Oncogene
, vol.22
, pp. 4702-4709
-
-
Gong, L.1
Nedeljkovic-Kurepa, A.2
Sarkar, F.H.3
-
54
-
-
11844254414
-
Normalization of tumor vasculature: An emerging concept in antiangiogenic therapy
-
Rakesh KJ. Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy. Science 2005;307:58-62.
-
(2005)
Science
, vol.307
, pp. 58-62
-
-
Rakesh, K.J.1
|