How NKG2D Ligands Trigger Autoimmunity?

Human Immunology

Volumn 67, Issue 3, 2006, Pages 204-207

  Caillat Zucman, Sophie ^a  

^a HÔPITAL SAINT VINCENT DE PAUL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

LIGAND; MAJOR HISTOCOMPATIBILITY ANTIGEN; NATURAL KILLER CELL RECEPTOR NKG2D;

ARTICLE; AUTOIMMUNE DISEASE; AUTOIMMUNITY; CELIAC DISEASE; DISEASE ASSOCIATION; DISEASE COURSE; DISEASE PREDISPOSITION; HUMAN; IMMUNE RESPONSE; INNATE IMMUNITY; INSULIN DEPENDENT DIABETES MELLITUS; PATHOGENESIS; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; T LYMPHOCYTE ACTIVATION;

ANIMALS; ARTHRITIS, RHEUMATOID; AUTOIMMUNE DISEASES; CD4-POSITIVE T-LYMPHOCYTES; CELIAC DISEASE; DIABETES MELLITUS, TYPE 1; GLIADIN; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; IMMUNITY, ACTIVE; IMMUNITY, NATURAL; INTERLEUKIN-15; LIGANDS; RECEPTORS, IMMUNOLOGIC;

EID: 33646364339     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humimm.2006.02.013     Document Type: Article

References (17)

1. Lanier L.L. NK cell recognition. Annu Rev Immunol 23 (2005) 225
2. Bauer S., Groh V., Wu J., Steinle A., Phillips J.H., Lanier L.L., and Spies T. Activation of NK cells and T cells by NKG2D, a receptor for stress- inducible MICA. Science 285 5428 (1999) 727
3. Groh V., Bruhl A., El-Gabalawy H., Nelson J.L., and Spies T. Stimulation of T cell autoreactivity by anomalous expression of NKG2D and its MIC ligands in rheumatoid arthritis. Proc Natl Acad Sci USA 100 16 (2003) 9452
4. Warrington K.J., Vallejo A.N., Weyand C.M., and Goronzy J.J. CD28 loss in senescent CD4+ T cells. reversal by interleukin-12 stimulation. Blood 101 9 (2003) 3543
5. Sollid L.M. Coeliac disease. dissecting a complex inflammatory disorder. Nat Rev Immunol 2 9 (2002) 647
6. Schuppan D., Dieterich W., and Riecken E.O. Exposing gliadin as a tasty food for lymphocytes. Nat Med 4 6 (1998) 666
7. Hue S., Mention J.J., Monteiro R.C., Zhang S., Cellier C., Schmitz J., Verkarre V., Fodil N., Bahram S., Cerf-Bensussan N., and Caillat-Zucman S. A direct role for NKG2D/MICA interaction in villous atrophy during celiac disease. Immunity 21 3 (2004) 367
8. Marsh M.N., and Crowe P.T. Morphology of the mucosal lesion in gluten sensitivity. Baillieres Clin Gastroenterol 9 2 (1995) 273
9. Maiuri L., Ciacci C., Ricciardelli I., Vacca L., Raia V., Auricchio S., Picard J., Osman M., Quaratino S., and Londei M. Association between innate response to gliadin and activation of pathogenic T cells in coeliac disease. Lancet 362 9377 (2003) 30
10. Maiuri L., Ciacci C., Auricchio S., Brown V., Quaratino S., and Londei M. Interleukin 15 mediates epithelial changes in celiac disease. Gastroenterology 119 4 (2000) 996
11. Mention J.J., Ben Ahmed M., Begue B., Barbe U., Verkarre V., Asnafi V., Colombel J.F., Cugnenc P.H., Ruemmele F.M., McIntyre E., Brousse N., Cellier C., and Cerf-Bensussan N. Interleukin 15. a key to disrupted intraepithelial lymphocyte homeostasis and lymphomagenesis in celiac disease. Gastroenterology 125 3 (2003) 730
12. Meresse B., Chen Z., Ciszewski C., Tretiakova M., Bhagat G., Krausz T.N., Raulet D.H., Lanier L.L., Groh V., Spies T., Ebert E.C., Green P.H., and Jabri B. Coordinated induction by IL15 of a TCR-independent NKG2D signaling pathway converts CTL into lymphokine-activated killer cells in celiac disease. Immunity 21 3 (2004) 357
13. Delovitch T.L., and Singh B. The nonobese diabetic mouse as a model of autoimmune diabetes. immune dysregulation gets the NOD. Immunity 7 6 (1997) 727
14. Ogasawara K., Hamerman J.A., Hsin H., Chikuma S., Bour-Jordan H., Chen T., Pertel T., Carnaud C., Bluestone J.A., and Lanier L.L. Impairment of NK cell function by NKG2D modulation in NOD mice. Immunity 18 1 (2003) 41
15. Diefenbach A., Tomasello E., Lucas M., Jamieson A.M., Hsia J.K., Vivier E., and Raulet D.H. Selective associations with signaling proteins determine stimulatory versus costimulatory activity of NKG2D. Nat Immunol 3 12 (2002) 1142
16. Bilbao J.R., Martin-Pagola A., Vitoria J.C., Zubillaga P., Ortiz L., and Castano L. HLA-DRB1 and MHC class 1 chain-related A haplotypes in Basque families with celiac disease. Tissue Antigens 60 1 (2002) 71
17. Gupta M., Nikitina-Zake L., Zarghami M., Landin-Olsson M., Kockum I., Lernmark A., and Sanjeevi C.B. Association between the transmembrane region polymorphism of MHC class I chain related gene-A and type 1 diabetes mellitus in Sweden. Hum Immunol 64 5 (2003) 553