Association between the transmembrane region polymorphism of MHC class I chain related gene-A and type 1 diabetes mellitus in Sweden

Human Immunology

Volumn 64, Issue 5, 2003, Pages 553-561

  Gupta, Manu ^a   Nikitina Zake, Liene ^a   Zarghami, Marjan ^c   Landin Olsson, Mona ^b   Kockum, Ingrid ^a   Lernmark, Åke ^c   Sanjeevi, Carani B ^a,d  

^a KAROLINSKA INSTITUTE   (Sweden)

^b LUND UNIVERSITY   (Sweden)

^c UNIVERSITY OF WASHINGTON   (United States)

^d KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Age; Autoimmune disease; Gender; HLA; Swedish population

Indexed keywords

GENE PRODUCT; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1;

ADOLESCENT; ADULT; AGE DISTRIBUTION; ARTICLE; AUTOIMMUNITY; CAUCASIAN; CONTROLLED STUDY; DISEASE COURSE; FEMALE; GENE LOCUS; GENETIC POLYMORPHISM; GENOTYPE; HETEROZYGOSITY; HLA TYPING; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MAJOR HISTOCOMPATIBILITY COMPLEX CLASS 1 CHAIN RELATED GENE A; MALE; ONSET AGE; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; SEX DIFFERENCE; SWEDEN;

EID: 0037404664     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0198-8859(03)00035-1     Document Type: Article

References (48)

1. Lernmark Å, Falorni A: Textbook of Diabetes. Oxford: Blackwell Science, 1997.
2. Sanjeevi CB, Lybrand TP, DeWeese C, Landin-Olsson M, Kockum I, Dahlquist G, Sundkvist G, Stenger D, Lernmark A: Polymorphic amino acid variations in HLA-DQ are associated with systematic physical property changes and occurrence of IDDM. Members of the Swedish Childhood Diabetes Study. Diabetes 44:125, 1995.
3. Ronningen KS, Spurkland A, Iwe T, Vartdal F, Thorsby E: Distribution of HLA-DRB1, -DQA1 and -DQB1 alleles and DQA1-DQB1 genotypes among Norwegian patients with insulin-dependent diabetes mellitus. Tissue Antigens 37:105, 1991.
4. Davies JL, Kawaguchi Y, Bennett ST, Copeman JB, Cordell HJ, Pritchard LE, Reed PW, Gough SC, Jenkins SC, Palmer SM, et al: A genome-wide search for human type 1 diabetes susceptibility genes. Nature 371:130, 1994.
5. Hashimoto L, Habita C, Beressi JP, Delepine M, Besse C, Cambon-Thomsen A, Deschamps I, Rotter JI, Djoulah S, James MR, et al: Genetic mapping of a susceptibility locus for insulin-dependent diabetes mellitus on chromosome 11q. Nature 371:161, 1994.
6. Field LL, Tobias R, Magnus T: A locus on chromosome 15q26 (IDDM3) produces susceptibility to insulin-dependent diabetes mellitus. Nat Genet 8:189, 1994.
7. Owerbach D, Gabbay KH: The HOXD8 locus (2q31) is linked to type I diabetes. Interaction with chromosome 6 and 11 disease susceptibility genes. Diabetes 44:132, 1995.
8. Nistico L, Buzzetti R, Pritchard LE, Van der Auwera B, Giovannini C, Bosi E, Larrad MT, Rios MS, Chow CC, Cockram CS, Jacobs K, Mijovic C, Bain SC, Barnett AH, Vandewalle CL, Schuit F, Gorus FK, Tosi R, Pozzilli P, Todd JA: The CTLA-4 gene region of chromosome 2q33 is linked to, and associated with, type 1 diabetes. Belgian Diabetes Registry. Hum Mol Genet 5:1075, 1996.
9. Bahram S, Bresnahan M, Geraghty DE, Spies T: A second lineage of mammalian major histocompatibility complex class I genes. Proc Natl Acad Sci USA 91:6259, 1994.
10. Bahram S, Spies T: The MIC gene family. Res Immunol 147:328, 1996.
11. Ota M, Katsuyama Y, Mizuki N, Ando H, Furihata K, Ono S, Pivetti-Pezzi P, Tabbara KF, Palimeris GD, Nikbin B, Davatchi F, Chams H, Geng Z, Bahram S, Inoko H: Trinucleotide repeat polymorphism within exon 5 of the MICA gene (MHC class I chain-related gene A): allele frequency data in the nine population groups Japanese, Northern Han, Hui, Uygur, Kazakhstan, Iranian, Saudi Arabian, Greek and Italian. Tissue Antigens 49:448, 1997.
12. Braud VM, Allan DS, McMichael AJ: Functions of non-classical MHC and non-MHC-encoded class I molecules. Curr Opin Immunol 11:100, 1999.
13. Groh V, Steinle A, Bauer S, Spies T: Recognition of stress-induced MHC molecules by intestinal epithelial gammadelta T cells. Science 279:1737, 1998.
14. Gambelunghe G, Ghaderi M, Cosentino A, Falorni A, Brunetti P, Sanjeevi CB: Association of MHC Class I chain-related A (MIC-A) gene polymorphism with type I diabetes. Diabetologia 43:507, 2000.
15. Gambelunghe G, Ghaderi M, Tortoioli C, Falorni A, Santeusanio F, Brunetti P, Sanjeevi CB: Two distinct MICA gene markers discriminate major autoimmune diabetes types. J Clin Endocrinol Metab 86:3754, 2001.
16. Kawabata Y, Ikegami H, Kawaguchi Y, Fujisawa T, Hotta M, Ueda H, Shintani M, Nojima K, Ono M, Nishino M, Taniguchi H, Noso S, Yamada K, Babaya N, Ogihara T: Age-related association of MHC class I chain-related gene A (MICA) with type 1 (insulin-dependent) diabetes mellitus. Hum Immunol 61:624, 2000.
17. Park Y, Lee H, Sanjeevi CB, Eisenbarth GS: MICA polymorphism is associated with type 1 diabetes in the Korean population. Diabetes Care 24:33, 2001.
18. Lee YJ, Huang FY, Wang CH, Lo FS, Tsan KW, Hsu CH, Huang CY, Chang SC, Chang JG: Polymorphism in the transmembrane region of the MICA gene and type 1 diabetes. J Pediatr Endocrinol Metab 13:489, 2000.
19. Zake LN, Ghaderi M, Park YS, Babu S, Eisenbarth G, Sanjeevi CB: MHC class I chain-related gene alleles 5 and 5.1 are transmitted more frequently to type 1 diabetes offspring in HBDI families. Ann NY Acad Sci 958:309, 2002.
20. Bahram S: MIC genes: from genetics to biology. Adv Immunol 76:1, 2000.
21. Gambelunghe G, Falorni A, Ghaderi M, Laureti S, Tortoioli C, Santeusanio F, Brunetti P, Sanjeevi CB: Microsatellite polymorphism of the MHC class I chain-related (MIC-A and MIC-B) genes marks the risk for autoimmune Addison's disease. J Clin Endocrinol Metab 84:3701, 1999.
22. Nikitina Zake L, Cimdina I, Rumba I, Dabadghao P, Sanjeevi CB: Major histocompatibility complex class I chain related (MIC) A gene, TNFa microsatellite alleles and TNFB alleles in juvenile idiopathic arthritis patients from Latvia. Hum Immunol 63:418, 2002.
23. Graham J, Kockum I, Sanjeevi CB, Landin-Olsson M, Nystrom L, Sundkvist G, Arnqvist H, Blohme G, Lithner F, Littorin B, Schersten B, Wibell L, Ostman J, Lernmark A, Breslow N, Dahlquist G: Negative association between type 1 diabetes and HLA DQB1*0602- DQA1*0102 is attenuated with age at onset. Swedish Childhood Diabetes Study Group. Eur J Immunogenet 26:117, 1999.
24. Landin-Olsson M, Palmer JP, Lernmark A, Blom L, Sundkvist G, Nystrom L, Dahlquist G: Predictive value of islet cell and insulin autoantibodies for type 1 (insulin-dependent) diabetes mellitus in a population-based study of newly-diagnosed diabetic and matched control children. Diabetologia 35:1068, 1992.
25. Landin-Olsson M, Karlsson FA, Lernmark A, Sundkvist G: Islet cell and thyrogastric antibodies in 633 consecutive 15- to 34-yr-old patients in the diabetes incidence study in Sweden. Diabetes 41:1022, 1992.
26. Kockum I, Sanjeevi CB, Eastman S, Landin-Olsson M, Dahlquist G, Lernmark A: Complex interaction between HLA DR and DQ in conferring risk for childhood type 1 diabetes. Eur J Immunogenet 26:361, 1999.
27. Sanjeevi CB, Landin-Olsson M, Kockum I, Dahlquist G, Lernmark A: Effects of the second HLA-DQ haplotype on the association with childhood insulin-dependent diabetes mellitus. Tissue Antigens 45:148, 1995.
28. Graham J, Hagopian WA, Kockum I, Li LS, Sanjeevi CB, Lowe RM, Schaefer JB, Zarghami M, Day HL, Landin-Olsson M, Palmer JP, Janer-Villanueva M, Hood L, Sundkvist G, Lernmark A, Breslow N, Dahlquist G, Blohme G: Genetic effects on age-dependent onset and islet cell autoantibody markers in type 1 diabetes. Diabetes 51: 1346, 2002.
29. Miettinen O: Estimability and estimation in case-referent studies. Am J Epidemiol 103:226, 1976.
30. Woolf: On estimating the relation between blood group and disease. Ann Hum Genet 19:226, 1955.
31. Svejgaard A, Ryder LP: HLA and disease associations: detecting the strongest association. Tissue Antigens 43: 18, 1994.
32. Undlien DE, Kockum I, Ronningen KS, Lowe R, Saanjeevi CB, Graham J, Lie BA, Akselsen HE, Lernmark A, Thorsby E: HLA associations in type 1 diabetes among patients not carrying high-risk DR3-DQ2 or DR4-DQ8 haplotypes. Tissue Antigens 54:543, 1999.
33. Laakso M, Pyorala K: Age of onset and type of diabetes. Diabetes Care 8:114, 1985.
34. Molbak AG, Christau B, Marner B, Borch-Johnsen K, Nerup J: Incidence of insulin-dependent diabetes mellitus in age groups over 30 years in Denmark. Diabet Med 11:650, 1994.
35. Betterle C, Fusari A, Presotto F, Dal Pra C, Pedini B, Lazzarotto F, Zanchetta R: Pancreatic autoantibodies in Italian patients with newly diagnosed type 1 diabetes mellitus under the age of 20 years. Ann NY Acad Sci 958:271, 2002.
36. Gorus FK, Goubert P, Semakula C, Vandewalle CL, De Schepper J, Scheen A, Christie MR, Pipeleers DG: IA-2-autoantibodies complement GAD65-autoantibodies in new-onset IDDM patients and help predict impending diabetes in their siblings. The Belgian Diabetes Registry. Diabetologia 40:95, 1997.
37. Vandewalle CL, Falorni A, Lernmark A, Goubert P, Dorchy H, Coucke W, Semakula C, Van der Auwera B, Kaufman L, Schuit FC, Pipeleers DG, Gorus FK: Associations of GAD65- and IA-2-autoantibodies with genetic risk markers in new-onset IDDM patients and their siblings. The Belgian Diabetes Registry. Diabetes Care 20: 1547, 1997.
38. Sabbah E, Savola K, Ebeling T, Kulmala P, Vahasalo P, Ilonen J, Salmela PI, Knip M: Genetic, autoimmune, and clinical characteristics of childhood- and adult-onset type 1 diabetes. Diabetes Care 23:1326, 2000.
39. Cucca F, Goy JV, Kawaguchi Y, Esposito L, Merriman ME, Wilson AJ, Cordell HJ, Bain SC, Todd JA: A male-female bias in type 1 diabetes and linkage to chromosome Xp in MHC HLA-DR3-positive patients. Nat Genet 19:301, 1998.
40. Shtauvere-Brameus A, Ghaderi M, Rumba I, Sanjeevi CB: Microsatellite allele 5 of MHC class I chain-related gene a increases the risk for insulin-dependent diabetes mellitus in Latvians. Ann NY Acad Sci 958:349, 2002.
41. Sanjeevi CB, Kanungo A, Berzina L, Shtauvere-Brameus A, Ghaderi M, Samal KC: MHC class I chain-related gene a alleles distinguish malnutrition-modulated diabetes, insulin-dependent diabetes, and non-insulin-dependent diabetes mellitus patients from eastern India. Ann NY Acad Sci 958:341, 2002.
42. Allcock R, Cheong K, Christiansen F, Witt C: Comment to: Gambelunghe, Ghaderi, Cosentino et al. Association of MHC class I chain-related A (MIC-A) gene polymorphism with type I diabetes. Diabetologia 43:507-514, 2000. Diabetologia 44:514, 2001.
43. Allcock R, Cheong K, Christiansen F, Witt C: Comment to: Gambelunghe, Ghaderi, Cosentino et al. Association of MHC class I chain-related A (MIC-A) gene polymorphism with type I diabetes. Diabetologia 43:507-514, 2000. Diabetologia 44:514, 2001.
44. Nejentsev S, Gombos Z, Laine AP, Veijola R, Knip M, Simell O, Vaarala O, Akerblom HK, Ilonen J: Non-class II HLA gene associated with type 1 diabetes maps to the 240-kb region near HLA-B. Diabetes 49:2217, 2000.
45. Bauer S, Groh V, Wu J, Steinle A, Phillips JH, Lanier LL, Spies T: Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA. Science 285:727, 1999.
46. Groh V, Rhinehart R, Randolph-Habecker J, Topp MS, Riddell SR, Spies T: Costimulation of CD8alphabeta T cells by NKG2D via engagement by MIC induced on virus-infected cells. Nat Immunol 2:255, 2001.
47. Diefenbach A, Raulet DH: Natural killer cells: stress out, turn on, tune in. Curr Biol 9:R851, 1999.
48. Suemizu H, Radosavljevic M, Kimura M, Sadahiro S, Yoshimura S, Bahram S, Inoko H: A basolateral sorting motif in the MICA cytoplasmic tail. Proc Natl Acad Sci USA 99:2971, 2002.