Leishmania major expresses a single dihydroxyacetone phosphate acyltransferase localized in the glycosome, important for rapid growth and survival at high cell density and essential for virulence

Journal of Biological Chemistry

Volumn 281, Issue 12, 2006, Pages 7952-7959

  Zufferey, Rachel ^a,b   Mamoun, Choukri Ben ^a  

^a UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

^b KANSAS STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETONE; ACYLATION; BIOCHEMISTRY; ETHERS; GENES; PATHOLOGY; PHOSPHATES; PHOSPHOLIPIDS;

CELL DENSITY; DIHYDROXYACETONE PHOSPHATES; PEROXISOME; PROTOZOAN PARASITES;

CELL CULTURE;

DIHYDROXYACETONE PHOSPHATE ACYLTRANSFERASE; GLYCEROL 3 PHOSPHATE ACYLTRANSFERASE; PALMITOYL COENZYME A; ACYLTRANSFERASE; GLYCEROL 1 PHOSPHATASE; GLYCEROL-1-PHOSPHATASE; GLYCERONE PHOSPHATE O ACYLTRANSFERASE; GLYCERONE-PHOSPHATE O-ACYLTRANSFERASE; LIPID; PHOSPHATASE; RECOMBINANT PROTEIN;

ARTICLE; CELL DENSITY; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME LOCALIZATION; ENZYME SPECIFICITY; FLOW CYTOMETRY; GENE IDENTIFICATION; LEISHMANIA MAJOR; LETHALITY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROMASTIGOTE; PROTEIN EXPRESSION; SURVIVAL TIME; VIRULENCE; AMINO ACID SEQUENCE; ANIMAL; CHEMISTRY; DOSE RESPONSE; GENETIC COMPLEMENTATION; GENETICS; GENOTYPE; KINETICS; LEISHMANIASIS; LIPID METABOLISM; METABOLISM; MICROBODY; MOLECULAR GENETICS; MOUSE; MUTATION; PARASITOLOGY; PATHOGENICITY; PLASMID; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY; TIME;

LEISHMANIA MAJOR; PROTOZOA;

ACYLTRANSFERASES; AMINO ACID SEQUENCE; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; FLOW CYTOMETRY; GENETIC COMPLEMENTATION TEST; GENOTYPE; KINETICS; LEISHMANIA MAJOR; LEISHMANIASIS; LIPID METABOLISM; LIPIDS; MICE; MICROBODIES; MOLECULAR SEQUENCE DATA; MUTATION; PALMITOYL COENZYME A; PHENOTYPE; PHOSPHORIC MONOESTER HYDROLASES; PLASMIDS; RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY, AMINO ACID; TIME FACTORS; VIRULENCE;

EID: 33646363339     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M512911200     Document Type: Article

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