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Volumn 324, Issue 3, 2006, Pages 449-456

Antimicrobial peptides are present in immune and host defense cells of the human respiratory and gastroinstestinal tracts

Author keywords

Antimicrobial peptide; Cathelicidin; Defensin; Gastrointestinal tract; Host defense; Human; Innate immunity; Lung

Indexed keywords

ANTIGEN; CATHELICIDIN; CATHELICIDIN ANTIMICROBIAL PEPTIDE LL 37; CD3 ANTIGEN; CD68 ANTIGEN; CD74 ANTIGEN; DEFENSIN; POLYPEPTIDE ANTIBIOTIC AGENT; PROTEIN HBD 1; PROTEIN HBD 2; UNCLASSIFIED DRUG;

EID: 33646340471     PISSN: 0302766X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00441-005-0127-7     Document Type: Article
Times cited : (35)

References (35)
  • 2
    • 0028942078 scopus 로고
    • FALL-39, a putative human peptide antibiotic, is cysteine-free and expressed in bone marrow and testis
    • U S A
    • Agerberth B, Gunne H, Odeberg J, Kogner P, Boman HG, Gudmundsson GH (1995) FALL-39, a putative human peptide antibiotic, is cysteine-free and expressed in bone marrow and testis. Proc Natl Acad Sci U S A 92:195-199
    • (1995) Proc Natl Acad Sci , vol.92 , pp. 195-199
    • Agerberth, B.1    Gunne, H.2    Odeberg, J.3    Kogner, P.4    Boman, H.G.5    Gudmundsson, G.H.6
  • 3
    • 0038364156 scopus 로고    scopus 로고
    • Cathelicidins - A family of multi-functional antimicrobial peptides
    • Bals R, Wilson JM (2003) Cathelicidins - a family of multi-functional antimicrobial peptides. Cell Mol Life Sci 60:711-720
    • (2003) Cell Mol Life Sci , vol.60 , pp. 711-720
    • Bals, R.1    Wilson, J.M.2
  • 4
    • 33646367271 scopus 로고
    • Morphological observations on the axial gland of Antedon bifida
    • De Ridder C, Dubois P, Lahaye M-C, Jangoux M (eds) Balkema, Rotterdam
    • Bals R, Heinzeller T, Welsch U, Rehkaemper G, Cobb J (1990) Morphological observations on the axial gland of Antedon bifida. In: De Ridder C, Dubois P, Lahaye M-C, Jangoux M (eds) Echinoderm research. Balkema, Rotterdam, pp 197-202
    • (1990) Echinoderm Research , pp. 197-202
    • Bals, R.1    Heinzeller, T.2    Welsch, U.3    Rehkaemper, G.4    Cobb, J.5
  • 5
    • 0032169557 scopus 로고    scopus 로고
    • Human beta-defensin 2 is a salt-sensitive peptide antibiotic expressed in human lung
    • Bals R, Wang X, Wu Z, Freeman, Banfa V, Zasloff M, Wilson J (1998a) Human beta-defensin 2 is a salt-sensitive peptide antibiotic expressed in human lung. J Clin Invest 102:874-880
    • (1998) J Clin Invest , vol.102 , pp. 874-880
    • Bals, R.1    Wang, X.2    Wu, Z.3    Freeman4    Banfa, V.5    Zasloff, M.6    Wilson, J.7
  • 6
    • 0032482980 scopus 로고    scopus 로고
    • The peptide antibiotic LL-37/hCAP-18 is expressed in epithelia of the human lung where it has broad antimicrobial activity at the airway surface
    • U S A
    • Bals R, Wang X, Zasloff M, Wilson JM (1998b) The peptide antibiotic LL-37/hCAP-18 is expressed in epithelia of the human lung where it has broad antimicrobial activity at the airway surface. Proc Natl Acad Sci U S A 95:9541-9546
    • (1998) Proc Natl Acad Sci , vol.95 , pp. 9541-9546
    • Bals, R.1    Wang, X.2    Zasloff, M.3    Wilson, J.M.4
  • 7
    • 0033560645 scopus 로고    scopus 로고
    • Transfer of a cathelicidin peptide antibiotic gene restores bacterial killing in a cystic fibrosis xenograft model
    • Bals R, Weiner DJ, Meegalla RL, Wilson JM (1999a) Transfer of a cathelicidin peptide antibiotic gene restores bacterial killing in a cystic fibrosis xenograft model. J Clin Invest 103:1113-1117
    • (1999) J Clin Invest , vol.103 , pp. 1113-1117
    • Bals, R.1    Weiner, D.J.2    Meegalla, R.L.3    Wilson, J.M.4
  • 8
    • 0032708355 scopus 로고    scopus 로고
    • Augmentation of innate host defense by expression of a cathelicidin antimicrobial peptide
    • Bals R, Weiner DJ, Moscioni AD, Meegalla RL, Wilson JM (1999b) Augmentation of innate host defense by expression of a cathelicidin antimicrobial peptide. Infect Immun 67:6084-6089
    • (1999) Infect Immun , vol.67 , pp. 6084-6089
    • Bals, R.1    Weiner, D.J.2    Moscioni, A.D.3    Meegalla, R.L.4    Wilson, J.M.5
  • 9
    • 0028933794 scopus 로고
    • Peptide antibiotics and their role in innate immunity
    • Boman HG (1995) Peptide antibiotics and their role in innate immunity. Annu Rev Immunol 13:61-92
    • (1995) Annu Rev Immunol , vol.13 , pp. 61-92
    • Boman, H.G.1
  • 10
    • 0036040263 scopus 로고    scopus 로고
    • Expression of beta-defensin 1 and 2 mRNA by human monocytes, macrophages and dendritic cells
    • Duits LA, Ravensbergen B, Rademaker M, Hiemstra PS, Nibbering PH (2002) Expression of beta-defensin 1 and 2 mRNA by human monocytes, macrophages and dendritic cells. Immunology 106:517-525
    • (2002) Immunology , vol.106 , pp. 517-525
    • Duits, L.A.1    Ravensbergen, B.2    Rademaker, M.3    Hiemstra, P.S.4    Nibbering, P.H.5
  • 11
    • 0030956070 scopus 로고    scopus 로고
    • The expression of the gene coding for the antibacterial peptide LL-37 is induced in human keratinocytes during inflammatory disorders
    • Frohm M, Agerberth B, Ahangari G, Stahle-Backdahl M, Liden S, Wigzell H, Gudmundsson GH (1997) The expression of the gene coding for the antibacterial peptide LL-37 is induced in human keratinocytes during inflammatory disorders. J Biol Chem 272:15258-15263
    • (1997) J Biol Chem , vol.272 , pp. 15258-15263
    • Frohm, M.1    Agerberth, B.2    Ahangari, G.3    Stahle-Backdahl, M.4    Liden, S.5    Wigzell, H.6    Gudmundsson, G.H.7
  • 14
    • 0030949875 scopus 로고    scopus 로고
    • Human beta-defensin-1 is a salt-sensitive antibiotic in lung that is inactivated in cystic fibrosis
    • Goldman MJ, Anderson GM, Stolzenberg ED, Kari UP, Zasloff M, Wilson JM (1997) Human beta-defensin-1 is a salt-sensitive antibiotic in lung that is inactivated in cystic fibrosis. Cell 88:553-560
    • (1997) Cell , vol.88 , pp. 553-560
    • Goldman, M.J.1    Anderson, G.M.2    Stolzenberg, E.D.3    Kari, U.P.4    Zasloff, M.5    Wilson, J.M.6
  • 15
    • 0029893253 scopus 로고    scopus 로고
    • The human gene FALL39 and processing of the cathelin precursor to the antibacterial peptide LL-37 in granulocytes
    • Gudmundsson GH, Agerberth B, Odeberg J, Bergman T, Olsson B, Salcedo R (1996) The human gene FALL39 and processing of the cathelin precursor to the antibacterial peptide LL-37 in granulocytes. Eur J Biochem 238:325-332
    • (1996) Eur J Biochem , vol.238 , pp. 325-332
    • Gudmundsson, G.H.1    Agerberth, B.2    Odeberg, J.3    Bergman, T.4    Olsson, B.5    Salcedo, R.6
  • 17
    • 0037335205 scopus 로고    scopus 로고
    • The cathelicidin anti-microbial peptide LL-37 is involved in re-epithelialization of human skin wounds and is lacking in chronic ulcer epithelium
    • Heilborn JD, Nilsson MF, Kratz G, Weber G, Sorensen O, Borregaard N, Stahle-Backdahl M (2003) The cathelicidin anti-microbial peptide LL-37 is involved in re-epithelialization of human skin wounds and is lacking in chronic ulcer epithelium. J Invest Dermatol 120:379-389
    • (2003) J Invest Dermatol , vol.120 , pp. 379-389
    • Heilborn, J.D.1    Nilsson, M.F.2    Kratz, G.3    Weber, G.4    Sorensen, O.5    Borregaard, N.6    Stahle-Backdahl, M.7
  • 18
    • 0037282323 scopus 로고    scopus 로고
    • Antimicrobial peptides: Current status and therapeutic potential
    • Koczulla AR, Bals R (2003) Antimicrobial peptides: current status and therapeutic potential. Drugs 63:389-406
    • (2003) Drugs , vol.63 , pp. 389-406
    • Koczulla, A.R.1    Bals, R.2
  • 20
    • 0028949278 scopus 로고
    • Human CAP18: A novel antimicrobial lipopolysaccharide-binding protein
    • Larrick J, Hirata M, Balint R, Lee J, Zhong J, Wright S (1995) Human CAP18: a novel antimicrobial lipopolysaccharide-binding protein. Infect Immun 63:1291-1297
    • (1995) Infect Immun , vol.63 , pp. 1291-1297
    • Larrick, J.1    Hirata, M.2    Balint, R.3    Lee, J.4    Zhong, J.5    Wright, S.6
  • 21
    • 0036135697 scopus 로고    scopus 로고
    • Cathelicidins: A family of endogenous antimicrobial peptides
    • Lehrer RI, Ganz T (2002) Cathelicidins: a family of endogenous antimicrobial peptides. Curr Opin Hematol 9:18-22
    • (2002) Curr Opin Hematol , vol.9 , pp. 18-22
    • Lehrer, R.I.1    Ganz, T.2
  • 22
    • 0025959114 scopus 로고
    • Defensins: Endogenous antibiotic peptides of animal cells
    • Lehrer R, Ganz T, Selsted M (1991) Defensins: endogenous antibiotic peptides of animal cells. Cell 64:229-230
    • (1991) Cell , vol.64 , pp. 229-230
    • Lehrer, R.1    Ganz, T.2    Selsted, M.3
  • 24
    • 0030912043 scopus 로고    scopus 로고
    • Separation of human alveolar macrophages by flow cytometry
    • Maus U, Rosseau S, Seeger W, Lohmeyer J (1997) Separation of human alveolar macrophages by flow cytometry. Am J Physiol 272:L566-L571
    • (1997) Am J Physiol , vol.272
    • Maus, U.1    Rosseau, S.2    Seeger, W.3    Lohmeyer, J.4
  • 25
    • 0031093274 scopus 로고    scopus 로고
    • Human airway epithelia express a beta-defensin
    • McCray PJ, Bentley L (1997) Human airway epithelia express a beta-defensin. Am J Respir Cell Mol Biol 16:343-349
    • (1997) Am J Respir Cell Mol Biol , vol.16 , pp. 343-349
    • McCray, P.J.1    Bentley, L.2
  • 27
    • 0035058454 scopus 로고    scopus 로고
    • Evaluation of the effects of peptide antibiotics human beta-defensins-1/-2 and LL-37 on histamine release and prostaglandin D(2) production from mast cells
    • Niyonsaba F, Someya A, Hirata M, Ogawa H, Nagaoka I (2001) Evaluation of the effects of peptide antibiotics human beta-defensins-1/-2 and LL-37 on histamine release and prostaglandin D(2) production from mast cells. Eur J Immunol 31:1066-1075
    • (2001) Eur J Immunol , vol.31 , pp. 1066-1075
    • Niyonsaba, F.1    Someya, A.2    Hirata, M.3    Ogawa, H.4    Nagaoka, I.5
  • 32
    • 0025630507 scopus 로고
    • Lymphoid specific gene expression of the adenovirus early region 3 promoter is mediated by NF-kB binding motifs
    • Williams J, Garcia J, Harich D, Pearson L, Wu F, Gaynor R (1990) Lymphoid specific gene expression of the adenovirus early region 3 promoter is mediated by NF-kB binding motifs. EMBO J 9:4435-4442
    • (1990) EMBO J , vol.9 , pp. 4435-4442
    • Williams, J.1    Garcia, J.2    Harich, D.3    Pearson, L.4    Wu, F.5    Gaynor, R.6
  • 34
    • 0034596945 scopus 로고    scopus 로고
    • LL-37, the neutrophil granule- and epithelial cell-derived cathelicidin, utilizes formyl peptide receptor-like 1 (FPRL1) as a receptor to chemoattract human peripheral blood neutrophils, monocytes, and T-cells
    • Yang D, Chen Q, Schmidt AP, Anderson GM, Wang JM, Wooters J, Oppenheim JJ, Chertov O (2000) LL-37, the neutrophil granule- and epithelial cell-derived cathelicidin, utilizes formyl peptide receptor-like 1 (FPRL1) as a receptor to chemoattract human peripheral blood neutrophils, monocytes, and T-cells. J Exp Med 192:1069-1074
    • (2000) J Exp Med , vol.192 , pp. 1069-1074
    • Yang, D.1    Chen, Q.2    Schmidt, A.P.3    Anderson, G.M.4    Wang, J.M.5    Wooters, J.6    Oppenheim, J.J.7    Chertov, O.8
  • 35
    • 0037165196 scopus 로고    scopus 로고
    • Antimicrobial peptides of multicellular organisms
    • Zasloff M (2002) Antimicrobial peptides of multicellular organisms. Nature 415:389-395
    • (2002) Nature , vol.415 , pp. 389-395
    • Zasloff, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.